STRINGSTRING
ENSSBOP00000000486 ENSSBOP00000000486 BAG5 BAG5 UBQLN2 UBQLN2 EPM2A EPM2A CDK2 CDK2 ENSSBOP00000039275 ENSSBOP00000039275 RNF19B RNF19B BBS7 BBS7 DNAAF4 DNAAF4 DAB2 DAB2 CLUL1 CLUL1 UBXN1 UBXN1 ENSSBOP00000038206 ENSSBOP00000038206 RNF19A RNF19A AXIN2 AXIN2 VCP VCP SMARCC1 SMARCC1 WAC WAC XPO1 XPO1 BTRC BTRC MKRN2 MKRN2 PSMC5 PSMC5 PSMC4 PSMC4 ENSSBOP00000036272 ENSSBOP00000036272 APOE APOE UBE2K UBE2K ENSSBOP00000035335 ENSSBOP00000035335 CCAR2 CCAR2 OSBPL7 OSBPL7 BAG2 BAG2 STYX STYX NOP53 NOP53 CDC20 CDC20 ENSSBOP00000033583 ENSSBOP00000033583 DAB2IP DAB2IP COMMD1 COMMD1 CSNK1E CSNK1E RNF14 RNF14 SGTA SGTA PSME2 PSME2 TRIM39-RPP21 TRIM39-RPP21 DDA1 DDA1 DVL1 DVL1 ENSSBOP00000030260 ENSSBOP00000030260 RHBDF1 RHBDF1 ENSSBOP00000029926 ENSSBOP00000029926 USP7 USP7 CLU CLU XBP1 XBP1 AXIN1 AXIN1 PSME3IP1 PSME3IP1 PIAS1 PIAS1 FOXF2 FOXF2 CAV1 CAV1 SIRT6 SIRT6 COP1 COP1 FBXW9 FBXW9 USP14 USP14 SMAD7 SMAD7 GABARAPL2 GABARAPL2 FBXW7 FBXW7 ZYG11B ZYG11B BAG6 BAG6 PARK7 PARK7 PINK1 PINK1 TRIB1 TRIB1 ENSSBOP00000023587 ENSSBOP00000023587 MAP1A MAP1A FHIT FHIT FBXO22 FBXO22 NKD2 NKD2 PITHD1 PITHD1 PKD1 PKD1 RNFT2 RNFT2 MARCHF7 MARCHF7 ENSSBOP00000021190 ENSSBOP00000021190 FMR1 FMR1 TMTC3 TMTC3 RNF185 RNF185 ENSSBOP00000020906 ENSSBOP00000020906 USP19 USP19 USP13 USP13 FBXW8 FBXW8 ENSSBOP00000020408 ENSSBOP00000020408 ZYG11A ZYG11A HECTD1 HECTD1 ENSSBOP00000019712 ENSSBOP00000019712 GABARAP GABARAP RNF217 RNF217 GIPC2 GIPC2 TTC36 TTC36 ENSSBOP00000018520 ENSSBOP00000018520 ENSSBOP00000018503 ENSSBOP00000018503 ENSSBOP00000018270 ENSSBOP00000018270 CAMLG CAMLG ENSSBOP00000017687 ENSSBOP00000017687 SVIP SVIP ENSSBOP00000017299 ENSSBOP00000017299 AQP11 AQP11 ENSSBOP00000016736 ENSSBOP00000016736 ENSSBOP00000016515 ENSSBOP00000016515 ENSSBOP00000016390 ENSSBOP00000016390 STUB1 STUB1 SH3RF2 SH3RF2 ARIH1 ARIH1 EIF3H EIF3H PSMF1 PSMF1 RNF144B RNF144B TRIB2 TRIB2 CA6-2 CA6-2 ENSSBOP00000015040 ENSSBOP00000015040 TMF1 TMF1 LRRK2 LRRK2 RAD23B RAD23B ENSSBOP00000014789 ENSSBOP00000014789 RYBP RYBP OPHN1 OPHN1 SDCBP SDCBP DESI1 DESI1 TMEM259 TMEM259 FZR1 FZR1 PSMD14 PSMD14 HSP90AB1 HSP90AB1 HERPUD1 HERPUD1 PSMC1 PSMC1 PSEN1 PSEN1 GCLC GCLC ENSSBOP00000013349 ENSSBOP00000013349 RBX1 RBX1 ANKIB1 ANKIB1 RAD23A RAD23A GABARAPL1 GABARAPL1 GSK3B GSK3B NFE2L2 NFE2L2 TCEB2 TCEB2 GSK3A GSK3A ENSSBOP00000011397 ENSSBOP00000011397 ENSSBOP00000011195 ENSSBOP00000011195 OGT OGT RACK1 RACK1 PSMC6 PSMC6 NUB1 NUB1 DET1 DET1 ENSSBOP00000010240 ENSSBOP00000010240 GIPC1 GIPC1 UBQLN4 UBQLN4 ENSSBOP00000009732 ENSSBOP00000009732 PRKCG PRKCG CDC20B CDC20B GIPC3 GIPC3 TREM2 TREM2 RNFT1 RNFT1 PLK1 PLK1 GNA12 GNA12 NUPR1 NUPR1 PSMD10 PSMD10 TRIB3 TRIB3 PSMC2 PSMC2 RPL11 RPL11 NUDT15 NUDT15 UBQLN1 UBQLN1 AKT1 AKT1 DDRGK1 DDRGK1 USP5 USP5 N4BP1 N4BP1 ENSSBOP00000005807 ENSSBOP00000005807 PRKN PRKN MAPK9 MAPK9 SH3RF3 SH3RF3 RNF144A RNF144A SIRT2 SIRT2 ZER1 ZER1 HSPBP1 HSPBP1 UFL1 UFL1 ARAF ARAF CBFA2T3 CBFA2T3 TLK2 TLK2 UCHL5 UCHL5 PABPN1L PABPN1L RNF180 RNF180 PRICKLE1 PRICKLE1 SOCS4 SOCS4 DNAJB2 DNAJB2 SOCS5 SOCS5 RCHY1 RCHY1 WNT10B WNT10B MDM2 MDM2 CSNK1D CSNK1D ENSSBOP00000002912 ENSSBOP00000002912 KLHL40 KLHL40 GLMN GLMN USP25 USP25 AURKA AURKA PSMC3 PSMC3 ENSSBOP00000001426 ENSSBOP00000001426 IL33 IL33 ENSSBOP00000000409 ENSSBOP00000000409
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSSBOP00000000486AAA domain-containing protein; Belongs to the AAA ATPase family. (216 aa)
BAG5BCL2 associated athanogene 5. (483 aa)
UBQLN2Ubiquilin 2. (624 aa)
EPM2AEPM2A glucan phosphatase, laforin. (193 aa)
CDK2Cyclin dependent kinase 2. (289 aa)
ENSSBOP00000039275Nudix hydrolase domain-containing protein. (162 aa)
RNF19BRing finger protein 19B. (436 aa)
BBS7Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa)
DNAAF4Dynein axonemal assembly factor 4. (376 aa)
DAB2DAB adaptor protein 2. (767 aa)
CLUL1Clusterin; Belongs to the clusterin family. (491 aa)
UBXN1UBX domain protein 1. (447 aa)
ENSSBOP00000038206Uncharacterized protein; Belongs to the universal ribosomal protein uL5 family. (176 aa)
RNF19ARBR-type E3 ubiquitin transferase. (838 aa)
AXIN2Axin 2. (842 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1040 aa)
WACWW domain containing adaptor with coiled-coil. (601 aa)
XPO1Exportin 1. (1056 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (590 aa)
MKRN2Makorin ring finger protein 2. (416 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (416 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
ENSSBOP00000036272Uncharacterized protein. (236 aa)
APOEApolipoprotein E. (261 aa)
UBE2KUbiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (209 aa)
ENSSBOP00000035335AAA domain-containing protein; Belongs to the AAA ATPase family. (395 aa)
CCAR2Cell cycle and apoptosis regulator 2. (1012 aa)
OSBPL7Oxysterol-binding protein; Belongs to the OSBP family. (850 aa)
BAG2BCL2 associated athanogene 2. (211 aa)
STYXSerine/threonine/tyrosine interacting protein. (180 aa)
NOP53Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (480 aa)
CDC20WD_REPEATS_REGION domain-containing protein. (520 aa)
ENSSBOP00000033583Uncharacterized protein. (583 aa)
DAB2IPDAB2 interacting protein. (1172 aa)
COMMD1Copper metabolism domain containing 1. (190 aa)
CSNK1EProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa)
RNF14RBR-type E3 ubiquitin transferase. (474 aa)
SGTASmall glutamine rich tetratricopeptide repeat containing alpha. (313 aa)
PSME2Proteasome activator subunit 2. (239 aa)
TRIM39-RPP21TRIM39-RPP21 readthrough. (345 aa)
DDA1DET1 and DDB1 associated 1. (102 aa)
DVL1Dishevelled segment polarity protein 1. (387 aa)
ENSSBOP00000030260HATPase_c domain-containing protein. (717 aa)
RHBDF1Rhomboid 5 homolog 1. (854 aa)
ENSSBOP00000029926AAA domain-containing protein; Belongs to the AAA ATPase family. (430 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1112 aa)
CLUClusterin. (535 aa)
XBP1BZIP domain-containing protein. (375 aa)
AXIN1Axin 1. (867 aa)
PSME3IP1Family with sequence similarity 192 member A. (254 aa)
PIAS1Protein inhibitor of activated STAT 1. (653 aa)
FOXF2Forkhead box F2. (406 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (147 aa)
SIRT6Sirtuin 6. (355 aa)
COP1COP1 E3 ubiquitin ligase. (650 aa)
FBXW9F-box and WD repeat domain containing 9. (478 aa)
USP14Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (492 aa)
SMAD7Mothers against decapentaplegic homolog. (492 aa)
GABARAPL2Uncharacterized protein. (254 aa)
FBXW7F-box and WD repeat domain containing 7. (706 aa)
ZYG11BZyg-11 family member B, cell cycle regulator. (737 aa)
BAG6BCL2 associated athanogene 6. (1129 aa)
PARK7DJ-1_PfpI domain-containing protein. (189 aa)
PINK1PTEN induced kinase 1. (550 aa)
TRIB1Tribbles pseudokinase 1. (206 aa)
ENSSBOP00000023587WD_REPEATS_REGION domain-containing protein. (467 aa)
MAP1AMicrotubule associated protein 1A. (2804 aa)
FHITBis(5'-adenosyl)-triphosphatase. (149 aa)
FBXO22F-box protein 22. (349 aa)
NKD2NKD inhibitor of WNT signaling pathway 2. (388 aa)
PITHD1PITH domain containing 1. (211 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4166 aa)
RNFT2Ring finger protein, transmembrane 2. (444 aa)
MARCHF7Membrane associated ring-CH-type finger 7. (703 aa)
ENSSBOP00000021190Uncharacterized protein. (640 aa)
FMR1Fragile X mental retardation 1. (611 aa)
TMTC3Transmembrane O-mannosyltransferase targeting cadherins 3. (915 aa)
RNF185Ring finger protein 185. (192 aa)
ENSSBOP00000020906DJ-1_PfpI domain-containing protein. (158 aa)
USP19Ubiquitin specific peptidase 19. (1416 aa)
USP13Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (826 aa)
FBXW8F-box and WD repeat domain containing 8. (547 aa)
ENSSBOP00000020408Uncharacterized protein; Belongs to the AAA ATPase family. (360 aa)
ZYG11AZyg-11 family member A, cell cycle regulator. (680 aa)
HECTD1HECT domain E3 ubiquitin protein ligase 1. (2611 aa)
ENSSBOP00000019712RBR-type E3 ubiquitin transferase. (484 aa)
GABARAPGABA type A receptor-associated protein. (117 aa)
RNF217RBR-type E3 ubiquitin transferase. (513 aa)
GIPC2GIPC PDZ domain containing family member 2. (314 aa)
TTC36Tetratricopeptide repeat domain 36. (182 aa)
ENSSBOP00000018520Uncharacterized protein. (602 aa)
ENSSBOP00000018503Ubiquitin-like domain-containing protein. (118 aa)
ENSSBOP00000018270Ubiquitin-like domain-containing protein. (132 aa)
CAMLGCalcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (295 aa)
ENSSBOP00000017687Uncharacterized protein. (136 aa)
SVIPUncharacterized protein. (77 aa)
ENSSBOP00000017299Uncharacterized protein. (226 aa)
AQP11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)
ENSSBOP00000016736AAA domain-containing protein. (399 aa)
ENSSBOP00000016515WD_REPEATS_REGION domain-containing protein. (279 aa)
ENSSBOP00000016390HATPase_c domain-containing protein. (631 aa)
STUB1STIP1 homology and U-box containing protein 1. (250 aa)
SH3RF2SH3 domain containing ring finger 2. (729 aa)
ARIH1RBR-type E3 ubiquitin transferase. (470 aa)
EIF3HEukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (367 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
RNF144BRBR-type E3 ubiquitin transferase. (303 aa)
TRIB2Tribbles pseudokinase 2. (343 aa)
CA6-2Uncharacterized protein. (229 aa)
ENSSBOP00000015040Uncharacterized protein. (229 aa)
TMF1TATA element modulatory factor 1. (1093 aa)
LRRK2Leucine rich repeat kinase 2. (2528 aa)
RAD23BUncharacterized protein. (409 aa)
ENSSBOP00000014789Uncharacterized protein. (622 aa)
RYBPRING1 and YY1 binding protein. (222 aa)
OPHN1Oligophrenin 1. (802 aa)
SDCBPSyndecan binding protein. (317 aa)
DESI1Desumoylating isopeptidase 1. (168 aa)
TMEM259Transmembrane protein 259. (513 aa)
FZR1Fizzy and cell division cycle 20 related 1. (496 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
HSP90AB1HATPase_c domain-containing protein. (621 aa)
HERPUD1Homocysteine inducible ER protein with ubiquitin like domain 1. (451 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (448 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
GCLCGlutamate-cysteine ligase catalytic subunit. (637 aa)
ENSSBOP00000013349Uncharacterized protein. (210 aa)
RBX1Ring-box 1. (105 aa)
ANKIB1RBR-type E3 ubiquitin transferase. (1089 aa)
RAD23ARAD23 homolog A, nucleotide excision repair protein. (365 aa)
GABARAPL1GABA type A receptor associated protein like 1. (146 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (606 aa)
TCEB2Uncharacterized protein. (104 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (425 aa)
ENSSBOP00000011397Uncharacterized protein. (111 aa)
ENSSBOP00000011195Uncharacterized protein. (124 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (988 aa)
RACK1Receptor for activated C kinase 1. (317 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (364 aa)
NUB1Negative regulator of ubiquitin like proteins 1. (576 aa)
DET1Uncharacterized protein. (561 aa)
ENSSBOP00000010240Uncharacterized protein. (349 aa)
GIPC1GIPC PDZ domain containing family member 1. (335 aa)
UBQLN4Ubiquilin 4. (597 aa)
ENSSBOP00000009732AN1-type domain-containing protein. (184 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa)
CDC20BCell division cycle 20B. (515 aa)
GIPC3GIPC PDZ domain containing family member 3. (290 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (232 aa)
RNFT1Ring finger protein, transmembrane 1. (398 aa)
PLK1Serine/threonine-protein kinase PLK. (602 aa)
GNA12G protein subunit alpha 12. (318 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (82 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (472 aa)
RPL11Uncharacterized protein; Belongs to the universal ribosomal protein uL5 family. (161 aa)
NUDT15Nudix hydrolase 15. (164 aa)
UBQLN1Ubiquilin 1. (537 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (486 aa)
DDRGK1DDRGK domain containing 1. (315 aa)
USP5Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (864 aa)
N4BP1NEDD4 binding protein 1. (810 aa)
ENSSBOP00000005807HH_signal domain-containing protein. (115 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
SH3RF3SH3 domain containing ring finger 3. (711 aa)
RNF144ARBR-type E3 ubiquitin transferase. (292 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
ZER1Zyg-11 related cell cycle regulator. (748 aa)
HSPBP1HSPA (Hsp70) binding protein 1. (377 aa)
UFL1UFM1 specific ligase 1. (792 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (611 aa)
CBFA2T3Uncharacterized protein. (572 aa)
TLK2Tousled like kinase 2. (734 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (317 aa)
PABPN1LPoly(A) binding protein nuclear 1 like, cytoplasmic. (274 aa)
RNF180Ring finger protein 180. (592 aa)
PRICKLE1Prickle planar cell polarity protein 1. (831 aa)
SOCS4Suppressor of cytokine signaling 4. (440 aa)
DNAJB2DnaJ heat shock protein family (Hsp40) member B2. (324 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
RCHY1Ring finger and CHY zinc finger domain containing 1. (261 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (376 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa)
CSNK1DCasein kinase 1 delta. (419 aa)
ENSSBOP00000002912Uncharacterized protein. (77 aa)
KLHL40Kelch like family member 40. (618 aa)
GLMNGlomulin, FKBP associated protein. (595 aa)
USP25Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family. (1110 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (401 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
ENSSBOP00000001426Uncharacterized protein. (375 aa)
IL33Interleukin 33. (270 aa)
ENSSBOP00000000409AAA domain-containing protein. (370 aa)
Your Current Organism:
Saimiri boliviensis
NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis
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