STRINGSTRING
TCOF1 TCOF1 KCNA5 KCNA5 ENSSBOP00000040666 ENSSBOP00000040666 CACNA1G CACNA1G DLG4 DLG4 PHF6 PHF6 ATG4B ATG4B YWHAE YWHAE GRID2 GRID2 DSP DSP KRT18 KRT18 ENSSBOP00000037867 ENSSBOP00000037867 P2RX7 P2RX7 ENSSBOP00000036393 ENSSBOP00000036393 PLCG2 PLCG2 KRT8 KRT8 ENSSBOP00000020796 ENSSBOP00000020796 ENSSBOP00000020906 ENSSBOP00000020906 CASP8 CASP8 SYK SYK ITPR2 ITPR2 LYN LYN ENSSBOP00000022867 ENSSBOP00000022867 BRAF BRAF PARK7 PARK7 ENSSBOP00000025694 ENSSBOP00000025694 SRC SRC PSAP PSAP ENSSBOP00000026965 ENSSBOP00000026965 ENSSBOP00000027488 ENSSBOP00000027488 ENSSBOP00000028148 ENSSBOP00000028148 ENSSBOP00000028747 ENSSBOP00000028747 HOMER1 HOMER1 FYN FYN BAIAP2 BAIAP2 CRIPT CRIPT NLGN1 NLGN1 ENSSBOP00000032602 ENSSBOP00000032602 LRP4 LRP4 ENSSBOP00000033214 ENSSBOP00000033214 MAP3K7 MAP3K7 ENSSBOP00000034092 ENSSBOP00000034092 CRK CRK ENSSBOP00000034299 ENSSBOP00000034299 IL6ST IL6ST CIT CIT PDE4D PDE4D ADCY5 ADCY5 ENSSBOP00000018403 ENSSBOP00000018403 ENSSBOP00000017687 ENSSBOP00000017687 ENSSBOP00000016822 ENSSBOP00000016822 XRCC6 XRCC6 DLL1 DLL1 CD163 CD163 SCN5A SCN5A CHUK CHUK ENSSBOP00000014658 ENSSBOP00000014658 CDC37 CDC37 ENSSBOP00000014288 ENSSBOP00000014288 ENSSBOP00000014203 ENSSBOP00000014203 MAP2K1 MAP2K1 CAV2 CAV2 ATP2B4 ATP2B4 IKBKB IKBKB GRM2 GRM2 TREM1 TREM1 NCK2 NCK2 NLGN3 NLGN3 TREM2 TREM2 KCNH2 KCNH2 ENSSBOP00000007146 ENSSBOP00000007146 KCNQ1 KCNQ1 CACNA1H CACNA1H SHANK1 SHANK1 NOS3 NOS3 P2RY1 P2RY1 SHANK3 SHANK3 NOS1 NOS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TCOF1Treacle ribosome biogenesis factor 1. (1519 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (602 aa)
ENSSBOP00000040666IF rod domain-containing protein; Belongs to the intermediate filament family. (257 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2377 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (763 aa)
PHF6PHD finger protein 6. (364 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (401 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (1007 aa)
DSPDesmoplakin. (2874 aa)
KRT18IF rod domain-containing protein; Belongs to the intermediate filament family. (413 aa)
ENSSBOP00000037867IF rod domain-containing protein; Belongs to the intermediate filament family. (417 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
ENSSBOP00000036393IF rod domain-containing protein; Belongs to the intermediate filament family. (347 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
KRT8IF rod domain-containing protein; Belongs to the intermediate filament family. (484 aa)
ENSSBOP00000020796IF rod domain-containing protein; Belongs to the intermediate filament family. (411 aa)
ENSSBOP00000020906DJ-1_PfpI domain-containing protein. (158 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (494 aa)
SYKNon-specific protein-tyrosine kinase. (566 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
LYNTyrosine-protein kinase. (512 aa)
ENSSBOP00000022867Ku domain-containing protein. (528 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (778 aa)
PARK7DJ-1_PfpI domain-containing protein. (189 aa)
ENSSBOP00000025694IF rod domain-containing protein; Belongs to the intermediate filament family. (471 aa)
SRCTyrosine-protein kinase. (542 aa)
PSAPProsaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. (524 aa)
ENSSBOP00000026965Ku domain-containing protein. (553 aa)
ENSSBOP00000027488IF rod domain-containing protein; Belongs to the intermediate filament family. (162 aa)
ENSSBOP00000028148Ku domain-containing protein. (545 aa)
ENSSBOP00000028747IF rod domain-containing protein; Belongs to the intermediate filament family. (265 aa)
HOMER1Homer scaffold protein 1. (357 aa)
FYNTyrosine-protein kinase. (537 aa)
BAIAP2BAI1 associated protein 2. (531 aa)
CRIPTCXXC repeat containing interactor of PDZ3 domain. (101 aa)
NLGN1Neuroligin 1. (823 aa)
ENSSBOP00000032602IF rod domain-containing protein; Belongs to the intermediate filament family. (406 aa)
LRP4LDL receptor related protein 4. (1908 aa)
ENSSBOP00000033214IF rod domain-containing protein; Belongs to the intermediate filament family. (480 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
ENSSBOP00000034092IF rod domain-containing protein; Belongs to the intermediate filament family. (152 aa)
CRKCRK proto-oncogene, adaptor protein. (249 aa)
ENSSBOP00000034299IF rod domain-containing protein; Belongs to the intermediate filament family. (166 aa)
IL6STInterleukin 6 signal transducer. (926 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2069 aa)
PDE4DPhosphodiesterase. (811 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1018 aa)
ENSSBOP00000018403Ku domain-containing protein. (505 aa)
ENSSBOP00000017687Uncharacterized protein. (136 aa)
ENSSBOP00000016822Ku_C domain-containing protein. (203 aa)
XRCC6SAP domain-containing protein. (361 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
CD163CD163 molecule. (1121 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2016 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (760 aa)
ENSSBOP00000014658IF rod domain-containing protein; Belongs to the intermediate filament family. (474 aa)
CDC37Cell division cycle 37. (336 aa)
ENSSBOP00000014288IF rod domain-containing protein; Belongs to the intermediate filament family. (424 aa)
ENSSBOP00000014203IF rod domain-containing protein; Belongs to the intermediate filament family. (420 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
CAV2Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (B [...] (162 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (750 aa)
GRM2Glutamate metabotropic receptor 2. (872 aa)
TREM1Triggering receptor expressed on myeloid cells 1. (235 aa)
NCK2Cytoplasmic protein. (380 aa)
NLGN3Neuroligin 3. (848 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (232 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1151 aa)
ENSSBOP00000007146Uncharacterized protein. (266 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (596 aa)
CACNA1HVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2291 aa)
SHANK1SH3 and multiple ankyrin repeat domains 1. (1334 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1459 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
Your Current Organism:
Saimiri boliviensis
NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis
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