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ATP2B2 ATP2B2 GABRA3 GABRA3 NECTIN3 NECTIN3 NLGN4X NLGN4X ABHD17B ABHD17B RNF10 RNF10 HTR5A HTR5A OPRD1 OPRD1 LRRC4C LRRC4C SHISA9 SHISA9 LRRTM2 LRRTM2 RGS9 RGS9 CHRNA9 CHRNA9 SORCS3 SORCS3 CACNG7 CACNG7 CHRNA10 CHRNA10 LRFN1 LRFN1 GSG1L GSG1L ARC ARC SLITRK1 SLITRK1 SCRIB SCRIB GABRB2 GABRB2 SLITRK3 SLITRK3 SIGMAR1 SIGMAR1 LRFN4 LRFN4 CDH10 CDH10 PTPRS PTPRS SHISA6 SHISA6 ADCY1 ADCY1 LIN7C LIN7C GRM1 GRM1 HSPA8 HSPA8 ENSSBOP00000033990 ENSSBOP00000033990 CACNG2 CACNG2 PLPPR4 PLPPR4 P2RX6 P2RX6 PTPRO PTPRO DLG2 DLG2 CACNG5 CACNG5 GRIN3A GRIN3A ENSSBOP00000036766 ENSSBOP00000036766 ENSSBOP00000036856 ENSSBOP00000036856 GRID1 GRID1 ADAM22 ADAM22 GRIN2B GRIN2B GRIA1 GRIA1 KPNA2 KPNA2 LRRTM3 LRRTM3 GRID2 GRID2 CHRNA1 CHRNA1 NETO1 NETO1 DLG4 DLG4 DLG1 DLG1 GRIN2C GRIN2C ABHD17C ABHD17C NPTX2 NPTX2 LRFN3 LRFN3 ENSSBOP00000026379 ENSSBOP00000026379 GRM5 GRM5 LIN7B LIN7B LRFN5 LRFN5 CNKSR2 CNKSR2 SHISA7 SHISA7 LIN7A LIN7A ERBB4 ERBB4 PRRT2 PRRT2 GLRA4 GLRA4 EFNB2 EFNB2 ACTN2 ACTN2 PRRT1 PRRT1 CHRNB1 CHRNB1 GRIN2A GRIN2A EPHA7 EPHA7 EPHA4 EPHA4 RGS7BP RGS7BP GABRA4 GABRA4 NLGN1 NLGN1 DCC DCC SLC16A3 SLC16A3 CLSTN2 CLSTN2 EFNB3 EFNB3 ENSSBOP00000022880 ENSSBOP00000022880 ABHD17A ABHD17A GRIN3B GRIN3B CACNA1C CACNA1C SORCS2 SORCS2 ENSSBOP00000020876 ENSSBOP00000020876 SEMA4C SEMA4C CNIH2 CNIH2 CHRND CHRND GPHN GPHN DAGLA DAGLA GRIN2D GRIN2D NRG1 NRG1 GABRA2 GABRA2 SYNDIG1 SYNDIG1 NLGN2 NLGN2 LRRC4 LRRC4 NRCAM NRCAM CHRNB2 CHRNB2 GABRA5 GABRA5 ENSSBOP00000011248 ENSSBOP00000011248 KCND3 KCND3 CACNG3 CACNG3 RAPSN RAPSN GRIK5 GRIK5 GRIA2 GRIA2 ENSSBOP00000009648 ENSSBOP00000009648 NLGN3 NLGN3 CACNG4 CACNG4 NPTN NPTN ENSSBOP00000007146 ENSSBOP00000007146 KCND2 KCND2 LRRTM1 LRRTM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
GABRA3Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (492 aa)
NECTIN3Nectin cell adhesion molecule 3. (503 aa)
NLGN4XNeuroligin 4 X-linked. (873 aa)
ABHD17BAbhydrolase domain containing 17B. (292 aa)
RNF10Ring finger protein 10. (755 aa)
HTR5A5-hydroxytryptamine receptor 5A. (357 aa)
OPRD1Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (331 aa)
LRRC4CLeucine rich repeat containing 4C. (640 aa)
SHISA9Shisa family member 9. (415 aa)
LRRTM2Leucine rich repeat transmembrane neuronal 2. (516 aa)
RGS9Regulator of G protein signaling 9. (680 aa)
CHRNA9Cholinergic receptor nicotinic alpha 9 subunit. (479 aa)
SORCS3Sortilin related VPS10 domain containing receptor 3. (1112 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (306 aa)
CHRNA10Cholinergic receptor nicotinic alpha 10 subunit. (450 aa)
LRFN1Leucine rich repeat and fibronectin type III domain containing 1. (1054 aa)
GSG1LGSG1 like. (195 aa)
ARCActivity regulated cytoskeleton associated protein. (398 aa)
SLITRK1SLIT and NTRK like family member 1. (696 aa)
SCRIBScribble planar cell polarity protein. (1655 aa)
GABRB2Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
SLITRK3SLIT and NTRK like family member 3. (979 aa)
SIGMAR1Sigma non-opioid intracellular receptor 1. (223 aa)
LRFN4Leucine rich repeat and fibronectin type III domain containing 4. (636 aa)
CDH10Cadherin 10; Cadherins are calcium-dependent cell adhesion proteins. (788 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1819 aa)
SHISA6Shisa family member 6. (454 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa)
LIN7CProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (197 aa)
GRM1Glutamate metabotropic receptor 1. (1194 aa)
HSPA8Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (646 aa)
ENSSBOP00000033990Importin subunit alpha; Functions in nuclear protein import. (470 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
PLPPR4Phospholipid phosphatase related 4. (715 aa)
P2RX6P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (362 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1216 aa)
DLG2Discs large MAGUK scaffold protein 2. (975 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (275 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1115 aa)
ENSSBOP00000036766Uncharacterized protein; Belongs to the heat shock protein 70 family. (562 aa)
ENSSBOP00000036856Importin subunit alpha; Functions in nuclear protein import. (515 aa)
GRID1Glutamate ionotropic receptor delta type subunit 1. (982 aa)
ADAM22ADAM metallopeptidase domain 22. (906 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1483 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (915 aa)
KPNA2Uncharacterized protein. (319 aa)
LRRTM3Leucine rich repeat transmembrane neuronal 3. (581 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (1007 aa)
CHRNA1Cholinergic receptor nicotinic alpha 1 subunit. (494 aa)
NETO1Neuropilin and tolloid like 1. (533 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (763 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (926 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1057 aa)
ABHD17CAbhydrolase domain containing 17C. (182 aa)
NPTX2Neuronal pentraxin 2. (494 aa)
LRFN3Leucine rich repeat and fibronectin type III domain containing 3. (626 aa)
ENSSBOP00000026379Uncharacterized protein; Belongs to the heat shock protein 70 family. (640 aa)
GRM5Glutamate metabotropic receptor 5. (1211 aa)
LIN7BLin-7 homolog B, crumbs cell polarity complex component. (194 aa)
LRFN5Leucine rich repeat and fibronectin type III domain containing 5. (750 aa)
CNKSR2Connector enhancer of kinase suppressor of Ras 2. (1034 aa)
SHISA7Shisa family member 7. (376 aa)
LIN7AProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (233 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
PRRT2Proline rich transmembrane protein 2. (340 aa)
GLRA4Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (452 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (336 aa)
ACTN2Actinin alpha 2. (791 aa)
PRRT1Uncharacterized protein. (83 aa)
CHRNB1Cholinergic receptor nicotinic beta 1 subunit. (501 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
EPHA7EPH receptor A7. (998 aa)
EPHA4EPH receptor A4. (949 aa)
RGS7BPRegulator of G protein signaling 7 binding protein. (257 aa)
GABRA4Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (553 aa)
NLGN1Neuroligin 1. (823 aa)
DCCDCC netrin 1 receptor. (1447 aa)
SLC16A3Solute carrier family 16 member 3. (462 aa)
CLSTN2Calsyntenin 2. (932 aa)
EFNB3Ephrin B3; Belongs to the ephrin family. (340 aa)
ENSSBOP00000022880Importin subunit alpha; Functions in nuclear protein import. (522 aa)
ABHD17AAbhydrolase domain containing 17A. (341 aa)
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (894 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2169 aa)
SORCS2Sortilin related VPS10 domain containing receptor 2. (1030 aa)
ENSSBOP00000020876Uncharacterized protein. (415 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (820 aa)
CNIH2Cornichon family AMPA receptor auxiliary protein 2. (160 aa)
CHRNDCholinergic receptor nicotinic delta subunit. (498 aa)
GPHNGephyrin. (809 aa)
DAGLADiacylglycerol lipase alpha. (1037 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (826 aa)
NRG1Neuregulin 1. (713 aa)
GABRA2Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (511 aa)
SYNDIG1Synapse differentiation inducing 1. (258 aa)
NLGN2Neuroligin 2. (850 aa)
LRRC4Leucine rich repeat containing 4. (609 aa)
NRCAMNeuronal cell adhesion molecule. (1304 aa)
CHRNB2Cholinergic receptor nicotinic beta 2 subunit. (502 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
ENSSBOP00000011248Importin subunit alpha; Functions in nuclear protein import. (479 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (655 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
RAPSNReceptor associated protein of the synapse. (412 aa)
GRIK5Glutamate ionotropic receptor kainate type subunit 5. (947 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
ENSSBOP00000009648Importin subunit alpha; Functions in nuclear protein import. (446 aa)
NLGN3Neuroligin 3. (848 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (299 aa)
NPTNNeuroplastin. (398 aa)
ENSSBOP00000007146Uncharacterized protein. (266 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa)
LRRTM1Leucine rich repeat transmembrane neuronal 1. (522 aa)
Your Current Organism:
Saimiri boliviensis
NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis
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