STRINGSTRING
SIRT6 SIRT6 PSMC6 PSMC6 NUB1 NUB1 DET1 DET1 ENSSBOP00000009732 ENSSBOP00000009732 CDC20B CDC20B TREM2 TREM2 UBQLN2 UBQLN2 RNF19B RNF19B BBS7 BBS7 DAB2 DAB2 CLUL1 CLUL1 RNF19A RNF19A AXIN2 AXIN2 VCP VCP MKRN2 MKRN2 PSMC5 PSMC5 PSMC4 PSMC4 ENSSBOP00000036272 ENSSBOP00000036272 ENSSBOP00000035335 ENSSBOP00000035335 OSBPL7 OSBPL7 BAG2 BAG2 NOP53 NOP53 CDC20 CDC20 DAB2IP DAB2IP CSNK1E CSNK1E RNF14 RNF14 SGTA SGTA DVL1 DVL1 ENSSBOP00000029926 ENSSBOP00000029926 CLU CLU XBP1 XBP1 AXIN1 AXIN1 PIAS1 PIAS1 CAV1 CAV1 RNFT1 RNFT1 PLK1 PLK1 NUPR1 NUPR1 PSMD10 PSMD10 COP1 COP1 FBXW9 FBXW9 SMAD7 SMAD7 FBXW7 FBXW7 ZYG11B ZYG11B BAG6 BAG6 TRIB1 TRIB1 ENSSBOP00000023587 ENSSBOP00000023587 FBXO22 FBXO22 NKD2 NKD2 RNFT2 RNFT2 ENSSBOP00000021190 ENSSBOP00000021190 FMR1 FMR1 TMTC3 TMTC3 RNF185 RNF185 USP13 USP13 TRIB3 TRIB3 GSK3A GSK3A FBXW8 FBXW8 ENSSBOP00000020408 ENSSBOP00000020408 ZYG11A ZYG11A HECTD1 HECTD1 ENSSBOP00000019712 ENSSBOP00000019712 GABARAP GABARAP RNF217 RNF217 ENSSBOP00000018503 ENSSBOP00000018503 ENSSBOP00000018270 ENSSBOP00000018270 ENSSBOP00000016736 ENSSBOP00000016736 ENSSBOP00000016515 ENSSBOP00000016515 STUB1 STUB1 ENSSBOP00000000409 ENSSBOP00000000409 ENSSBOP00000000486 ENSSBOP00000000486 IL33 IL33 ENSSBOP00000001426 ENSSBOP00000001426 PSMC3 PSMC3 AURKA AURKA KLHL40 KLHL40 CSNK1D CSNK1D MDM2 MDM2 RCHY1 RCHY1 SOCS5 SOCS5 DNAJB2 DNAJB2 SOCS4 SOCS4 PRICKLE1 PRICKLE1 RNF180 RNF180 CBFA2T3 CBFA2T3 HSPBP1 HSPBP1 ZER1 ZER1 SIRT2 SIRT2 RNF144A RNF144A SH3RF3 SH3RF3 MAPK9 MAPK9 PRKN PRKN USP5 USP5 DDRGK1 DDRGK1 AKT1 AKT1 PSMC2 PSMC2 SH3RF2 SH3RF2 ARIH1 ARIH1 RNF144B RNF144B TCEB2 TCEB2 NFE2L2 NFE2L2 GSK3B GSK3B GABARAPL1 GABARAPL1 RAD23A RAD23A ANKIB1 ANKIB1 RBX1 RBX1 GCLC GCLC PSEN1 PSEN1 PSMC1 PSMC1 HERPUD1 HERPUD1 FZR1 FZR1 TMEM259 TMEM259 LRRK2 LRRK2 TRIB2 TRIB2 ENSSBOP00000011195 ENSSBOP00000011195 RACK1 RACK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SIRT6Sirtuin 6. (355 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (364 aa)
NUB1Negative regulator of ubiquitin like proteins 1. (576 aa)
DET1Uncharacterized protein. (561 aa)
ENSSBOP00000009732AN1-type domain-containing protein. (184 aa)
CDC20BCell division cycle 20B. (515 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (232 aa)
UBQLN2Ubiquilin 2. (624 aa)
RNF19BRing finger protein 19B. (436 aa)
BBS7Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa)
DAB2DAB adaptor protein 2. (767 aa)
CLUL1Clusterin; Belongs to the clusterin family. (491 aa)
RNF19ARBR-type E3 ubiquitin transferase. (838 aa)
AXIN2Axin 2. (842 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
MKRN2Makorin ring finger protein 2. (416 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (416 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
ENSSBOP00000036272Uncharacterized protein. (236 aa)
ENSSBOP00000035335AAA domain-containing protein; Belongs to the AAA ATPase family. (395 aa)
OSBPL7Oxysterol-binding protein; Belongs to the OSBP family. (850 aa)
BAG2BCL2 associated athanogene 2. (211 aa)
NOP53Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (480 aa)
CDC20WD_REPEATS_REGION domain-containing protein. (520 aa)
DAB2IPDAB2 interacting protein. (1172 aa)
CSNK1EProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa)
RNF14RBR-type E3 ubiquitin transferase. (474 aa)
SGTASmall glutamine rich tetratricopeptide repeat containing alpha. (313 aa)
DVL1Dishevelled segment polarity protein 1. (387 aa)
ENSSBOP00000029926AAA domain-containing protein; Belongs to the AAA ATPase family. (430 aa)
CLUClusterin. (535 aa)
XBP1BZIP domain-containing protein. (375 aa)
AXIN1Axin 1. (867 aa)
PIAS1Protein inhibitor of activated STAT 1. (653 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (147 aa)
RNFT1Ring finger protein, transmembrane 1. (398 aa)
PLK1Serine/threonine-protein kinase PLK. (602 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (82 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
COP1COP1 E3 ubiquitin ligase. (650 aa)
FBXW9F-box and WD repeat domain containing 9. (478 aa)
SMAD7Mothers against decapentaplegic homolog. (492 aa)
FBXW7F-box and WD repeat domain containing 7. (706 aa)
ZYG11BZyg-11 family member B, cell cycle regulator. (737 aa)
BAG6BCL2 associated athanogene 6. (1129 aa)
TRIB1Tribbles pseudokinase 1. (206 aa)
ENSSBOP00000023587WD_REPEATS_REGION domain-containing protein. (467 aa)
FBXO22F-box protein 22. (349 aa)
NKD2NKD inhibitor of WNT signaling pathway 2. (388 aa)
RNFT2Ring finger protein, transmembrane 2. (444 aa)
ENSSBOP00000021190Uncharacterized protein. (640 aa)
FMR1Fragile X mental retardation 1. (611 aa)
TMTC3Transmembrane O-mannosyltransferase targeting cadherins 3. (915 aa)
RNF185Ring finger protein 185. (192 aa)
USP13Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (826 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (425 aa)
FBXW8F-box and WD repeat domain containing 8. (547 aa)
ENSSBOP00000020408Uncharacterized protein; Belongs to the AAA ATPase family. (360 aa)
ZYG11AZyg-11 family member A, cell cycle regulator. (680 aa)
HECTD1HECT domain E3 ubiquitin protein ligase 1. (2611 aa)
ENSSBOP00000019712RBR-type E3 ubiquitin transferase. (484 aa)
GABARAPGABA type A receptor-associated protein. (117 aa)
RNF217RBR-type E3 ubiquitin transferase. (513 aa)
ENSSBOP00000018503Ubiquitin-like domain-containing protein. (118 aa)
ENSSBOP00000018270Ubiquitin-like domain-containing protein. (132 aa)
ENSSBOP00000016736AAA domain-containing protein. (399 aa)
ENSSBOP00000016515WD_REPEATS_REGION domain-containing protein. (279 aa)
STUB1STIP1 homology and U-box containing protein 1. (250 aa)
ENSSBOP00000000409AAA domain-containing protein. (370 aa)
ENSSBOP00000000486AAA domain-containing protein; Belongs to the AAA ATPase family. (216 aa)
IL33Interleukin 33. (270 aa)
ENSSBOP00000001426Uncharacterized protein. (375 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (401 aa)
KLHL40Kelch like family member 40. (618 aa)
CSNK1DCasein kinase 1 delta. (419 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa)
RCHY1Ring finger and CHY zinc finger domain containing 1. (261 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
DNAJB2DnaJ heat shock protein family (Hsp40) member B2. (324 aa)
SOCS4Suppressor of cytokine signaling 4. (440 aa)
PRICKLE1Prickle planar cell polarity protein 1. (831 aa)
RNF180Ring finger protein 180. (592 aa)
CBFA2T3Uncharacterized protein. (572 aa)
HSPBP1HSPA (Hsp70) binding protein 1. (377 aa)
ZER1Zyg-11 related cell cycle regulator. (748 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
RNF144ARBR-type E3 ubiquitin transferase. (292 aa)
SH3RF3SH3 domain containing ring finger 3. (711 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
USP5Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (864 aa)
DDRGK1DDRGK domain containing 1. (315 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (486 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (472 aa)
SH3RF2SH3 domain containing ring finger 2. (729 aa)
ARIH1RBR-type E3 ubiquitin transferase. (470 aa)
RNF144BRBR-type E3 ubiquitin transferase. (303 aa)
TCEB2Uncharacterized protein. (104 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (606 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
GABARAPL1GABA type A receptor associated protein like 1. (146 aa)
RAD23ARAD23 homolog A, nucleotide excision repair protein. (365 aa)
ANKIB1RBR-type E3 ubiquitin transferase. (1089 aa)
RBX1Ring-box 1. (105 aa)
GCLCGlutamate-cysteine ligase catalytic subunit. (637 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (448 aa)
HERPUD1Homocysteine inducible ER protein with ubiquitin like domain 1. (451 aa)
FZR1Fizzy and cell division cycle 20 related 1. (496 aa)
TMEM259Transmembrane protein 259. (513 aa)
LRRK2Leucine rich repeat kinase 2. (2528 aa)
TRIB2Tribbles pseudokinase 2. (343 aa)
ENSSBOP00000011195Uncharacterized protein. (124 aa)
RACK1Receptor for activated C kinase 1. (317 aa)
Your Current Organism:
Saimiri boliviensis
NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis
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