(12 nodes) WH1/EVH1 domain network (Saimiri boliviensis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

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protein homology

Your Input:
	SPRED2	Sprouty related EVH1 domain containing 2. (432 aa)
	EVL	Enah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (422 aa)
	HOMER2	Homer scaffold protein 2. (351 aa)
	VASP	WH1 domain-containing protein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (381 aa)
	ENSSBOP00000025090	WH1 domain-containing protein. (357 aa)
	HOMER3	WH1 domain-containing protein. (361 aa)
	HOMER1	Homer scaffold protein 1. (357 aa)
	SPRED1	Sprouty related EVH1 domain containing 1. (444 aa)
	WAS	WASP actin nucleation promoting factor. (502 aa)
	ENAH	ENAH actin regulator. (793 aa)
	SPRED3	Sprouty related EVH1 domain containing 3. (430 aa)
	WASL	WASP like actin nucleation promoting factor. (507 aa)

Your Current Organism:

Saimiri boliviensis

NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENAH	ENSSBOP00000025090	ENSSBOP00000032402	ENSSBOP00000025090	ENAH actin regulator.	WH1 domain-containing protein.	0.888
ENAH	EVL	ENSSBOP00000032402	ENSSBOP00000008876	ENAH actin regulator.	Enah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family.	0.950
ENAH	VASP	ENSSBOP00000032402	ENSSBOP00000017271	ENAH actin regulator.	WH1 domain-containing protein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family.	0.888
ENSSBOP00000025090	ENAH	ENSSBOP00000025090	ENSSBOP00000032402	WH1 domain-containing protein.	ENAH actin regulator.	0.888
ENSSBOP00000025090	EVL	ENSSBOP00000025090	ENSSBOP00000008876	WH1 domain-containing protein.	Enah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family.	0.903
EVL	ENAH	ENSSBOP00000008876	ENSSBOP00000032402	Enah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family.	ENAH actin regulator.	0.950
EVL	ENSSBOP00000025090	ENSSBOP00000008876	ENSSBOP00000025090	Enah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family.	WH1 domain-containing protein.	0.903
EVL	VASP	ENSSBOP00000008876	ENSSBOP00000017271	Enah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family.	WH1 domain-containing protein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family.	0.989
HOMER1	HOMER2	ENSSBOP00000028915	ENSSBOP00000017118	Homer scaffold protein 1.	Homer scaffold protein 2.	0.975
HOMER1	HOMER3	ENSSBOP00000028915	ENSSBOP00000028876	Homer scaffold protein 1.	WH1 domain-containing protein.	0.992
HOMER2	HOMER1	ENSSBOP00000017118	ENSSBOP00000028915	Homer scaffold protein 2.	Homer scaffold protein 1.	0.975
HOMER2	HOMER3	ENSSBOP00000017118	ENSSBOP00000028876	Homer scaffold protein 2.	WH1 domain-containing protein.	0.966
HOMER3	HOMER1	ENSSBOP00000028876	ENSSBOP00000028915	WH1 domain-containing protein.	Homer scaffold protein 1.	0.992
HOMER3	HOMER2	ENSSBOP00000028876	ENSSBOP00000017118	WH1 domain-containing protein.	Homer scaffold protein 2.	0.966
SPRED1	SPRED2	ENSSBOP00000031429	ENSSBOP00000000111	Sprouty related EVH1 domain containing 1.	Sprouty related EVH1 domain containing 2.	0.716
SPRED2	SPRED1	ENSSBOP00000000111	ENSSBOP00000031429	Sprouty related EVH1 domain containing 2.	Sprouty related EVH1 domain containing 1.	0.716
VASP	ENAH	ENSSBOP00000017271	ENSSBOP00000032402	WH1 domain-containing protein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family.	ENAH actin regulator.	0.888
VASP	EVL	ENSSBOP00000017271	ENSSBOP00000008876	WH1 domain-containing protein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family.	Enah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family.	0.989
VASP	WAS	ENSSBOP00000017271	ENSSBOP00000032249	WH1 domain-containing protein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family.	WASP actin nucleation promoting factor.	0.866
WAS	VASP	ENSSBOP00000032249	ENSSBOP00000017271	WASP actin nucleation promoting factor.	WH1 domain-containing protein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family.	0.866