STRINGSTRING
CERS1 CERS1 DEGS2 DEGS2 ENSSBOP00000000783 ENSSBOP00000000783 SPHK1 SPHK1 SGPP2 SGPP2 SPTSSB SPTSSB PPAP2C PPAP2C OSBP OSBP PLPP1 PLPP1 PPAP2B PPAP2B ALDH3B1 ALDH3B1 ORMDL3 ORMDL3 KDSR KDSR SPNS2 SPNS2 ALDH3B2 ALDH3B2 VAPB VAPB CERS4 CERS4 PPM1L PPM1L ACER3 ACER3 ISM2 ISM2 SGMS1 SGMS1 LINS1 LINS1 CERS3 CERS3 SAMD8 SAMD8 SGMS2 SGMS2 ENSSBOP00000018609 ENSSBOP00000018609 CSNK1G1 CSNK1G1 CERS6 CERS6 SPTLC1 SPTLC1 CERT1 CERT1 PRKD3 PRKD3 ACER1 ACER1 SPTLC3 SPTLC3 SPTLC2 SPTLC2 ISM1 ISM1 CSNK1G2 CSNK1G2 DEGS1 DEGS1 FA2H FA2H SGPL1 SGPL1 SPHK2 SPHK2 ORMDL2 ORMDL2 ACER2 ACER2 ORMDL1 ORMDL1 ENSSBOP00000034297 ENSSBOP00000034297 CSNK1G3 CSNK1G3 CERS2 CERS2 SGPP1 SGPP1 CERS5 CERS5 VAPA VAPA PRKD2 PRKD2 PRKD1 PRKD1 ALDH3A2 ALDH3A2 SPTSSA SPTSSA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CERS1TLC domain-containing protein. (239 aa)
DEGS2Delta 4-desaturase, sphingolipid 2. (323 aa)
ENSSBOP00000000783Uncharacterized protein. (129 aa)
SPHK1Sphingosine kinase 1. (488 aa)
SGPP2Sphingosine-1-phosphate phosphatase 2. (353 aa)
SPTSSBSerine palmitoyltransferase small subunit B. (76 aa)
PPAP2CacidPPc domain-containing protein. (224 aa)
OSBPOxysterol-binding protein; Belongs to the OSBP family. (724 aa)
PLPP1Phospholipid phosphatase 1. (284 aa)
PPAP2BacidPPc domain-containing protein. (311 aa)
ALDH3B1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (468 aa)
ORMDL3ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
KDSR3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
SPNS2Sphingolipid transporter 2. (521 aa)
ALDH3B2Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (497 aa)
VAPBVAMP associated protein B and C. (243 aa)
CERS4Ceramide synthase 4. (400 aa)
PPM1LProtein phosphatase, Mg2+/Mn2+ dependent 1L. (360 aa)
ACER3Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (225 aa)
ISM2Isthmin 2. (553 aa)
SGMS1Sphingomyelin synthase 1. (413 aa)
LINS1Lines homolog 1. (756 aa)
CERS3Ceramide synthase 3. (382 aa)
SAMD8Sterile alpha motif domain containing 8. (500 aa)
SGMS2Sphingomyelin synthase 2. (365 aa)
ENSSBOP00000018609Uncharacterized protein. (94 aa)
CSNK1G1Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. (475 aa)
CERS6Ceramide synthase 6. (375 aa)
SPTLC1Aminotran_1_2 domain-containing protein. (498 aa)
CERT1Ceramide transporter 1. (736 aa)
PRKD3Protein kinase D3. (758 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa)
SPTLC3Serine palmitoyltransferase long chain base subunit 3. (553 aa)
SPTLC2Serine palmitoyltransferase long chain base subunit 2. (497 aa)
ISM1Isthmin 1. (418 aa)
CSNK1G2Casein kinase 1 gamma 2; Belongs to the protein kinase superfamily. (415 aa)
DEGS1Delta 4-desaturase, sphingolipid 1. (323 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (568 aa)
SPHK2Sphingosine kinase 2. (656 aa)
ORMDL2ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
ORMDL1ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
ENSSBOP00000034297Protein kinase domain-containing protein. (334 aa)
CSNK1G3Casein kinase 1 gamma 3; Belongs to the protein kinase superfamily. (455 aa)
CERS2Ceramide synthase 2. (431 aa)
SGPP1Sphingosine-1-phosphate phosphatase 1. (372 aa)
CERS5Ceramide synthase 5. (426 aa)
VAPAVAMP associated protein A. (295 aa)
PRKD2Protein kinase D2. (788 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (824 aa)
ALDH3A2Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (508 aa)
SPTSSASerine palmitoyltransferase small subunit A. (71 aa)
Your Current Organism:
Saimiri boliviensis
NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis
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