STRINGSTRING
ITGB8 ITGB8 ENSSBOP00000023518 ENSSBOP00000023518 USP15 USP15 UBE2M UBE2M LTBP1 LTBP1 SMAD7 SMAD7 NEDD8 NEDD8 TGFBR2 TGFBR2 ENSSBOP00000035130 ENSSBOP00000035130 ENSSBOP00000035224 ENSSBOP00000035224 ENSSBOP00000035389 ENSSBOP00000035389 PPP1R15A PPP1R15A ENSSBOP00000036404 ENSSBOP00000036404 XPO1 XPO1 NEDD4L NEDD4L PPP1CC PPP1CC ZFYVE9 ZFYVE9 RPS27A RPS27A ITGA8 ITGA8 SMAD2 SMAD2 ITGB3 ITGB3 LTBP3 LTBP3 PPP1CB PPP1CB STRAP STRAP ENSSBOP00000003537 ENSSBOP00000003537 PMEPA1 PMEPA1 TGFB1 TGFB1 TGFBR1 TGFBR1 ENSSBOP00000005593 ENSSBOP00000005593 ENSSBOP00000006203 ENSSBOP00000006203 ITGB5 ITGB5 SMAD3 SMAD3 ENSSBOP00000009071 ENSSBOP00000009071 ITGAV ITGAV LDLRAD4 LDLRAD4 UBA52 UBA52 ENSSBOP00000014943 ENSSBOP00000014943 PCSK4 PCSK4 ITGB1 ITGB1 CBL CBL ITGB6 ITGB6 SMAD4 SMAD4 TGFB2 TGFB2 FKBP1A FKBP1A ENSSBOP00000015679 ENSSBOP00000015679 TGFB3 TGFB3 STUB1 STUB1 FBN1 FBN1 MTMR4 MTMR4 ENSSBOP00000017518 ENSSBOP00000017518 FURIN FURIN LTBP2 LTBP2 ENSSBOP00000019452 ENSSBOP00000019452 BAMBI BAMBI LTBP4 LTBP4 SMURF2 SMURF2 SMURF1 SMURF1 ENSSBOP00000020952 ENSSBOP00000020952
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITGB8Integrin beta; Belongs to the integrin beta chain family. (770 aa)
ENSSBOP00000023518WD_REPEATS_REGION domain-containing protein. (292 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
UBE2MUbiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1554 aa)
SMAD7Mothers against decapentaplegic homolog. (492 aa)
NEDD8Ubiquitin-like domain-containing protein. (81 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
ENSSBOP00000035130Ubiquitin-like domain-containing protein. (135 aa)
ENSSBOP00000035224Ubiquitin-like domain-containing protein. (65 aa)
ENSSBOP00000035389Ubiquitin-like domain-containing protein. (73 aa)
PPP1R15AProtein phosphatase 1 regulatory subunit 15A. (709 aa)
ENSSBOP00000036404Peptidylprolyl isomerase. (97 aa)
XPO1Exportin 1. (1056 aa)
NEDD4LNEDD4 like E3 ubiquitin protein ligase. (1254 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1424 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (800 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1214 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
STRAPSerine/threonine kinase receptor associated protein. (363 aa)
ENSSBOP00000003537Ubiquitin-like domain-containing protein. (155 aa)
PMEPA1Prostate transmembrane protein, androgen induced 1. (252 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (397 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
ENSSBOP00000005593Serine/threonine-protein phosphatase. (288 aa)
ENSSBOP00000006203Ubiquitin-like domain-containing protein. (156 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (875 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
ENSSBOP00000009071Ubiquitin-like domain-containing protein. (81 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1056 aa)
LDLRAD4Low density lipoprotein receptor class A domain containing 4. (306 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
ENSSBOP00000014943SER_THR_PHOSPHATASE domain-containing protein. (264 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4. (626 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
CBLCbl proto-oncogene. (748 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
FKBP1APeptidylprolyl isomerase. (128 aa)
ENSSBOP00000015679Peptidylprolyl isomerase. (127 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
STUB1STIP1 homology and U-box containing protein 1. (250 aa)
FBN1Fibrillin 1. (2872 aa)
MTMR4Myotubularin related protein 4. (1208 aa)
ENSSBOP00000017518Peptidylprolyl isomerase. (132 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa)
LTBP2Latent transforming growth factor beta binding protein 2. (1814 aa)
ENSSBOP00000019452Ubiquitin-like domain-containing protein. (135 aa)
BAMBIBMP and activin membrane bound inhibitor. (218 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1598 aa)
SMURF2E3 ubiquitin-protein ligase. (738 aa)
SMURF1E3 ubiquitin-protein ligase. (745 aa)
ENSSBOP00000020952Ubiquitin-like domain-containing protein. (140 aa)
Your Current Organism:
Saimiri boliviensis
NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis
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