STRINGSTRING
ATP2B1 ATP2B1 ENSSBOP00000010982 ENSSBOP00000010982 ITPR3 ITPR3 ENSSBOP00000010565 ENSSBOP00000010565 P2RX2 P2RX2 SLC8A1 SLC8A1 ENSSBOP00000007060 ENSSBOP00000007060 GUCY1A2 GUCY1A2 ATP2B2 ATP2B2 TRPC6 TRPC6 ENSSBOP00000005799 ENSSBOP00000005799 GUCY1B1 GUCY1B1 NOS3 NOS3 GNG3 GNG3 GNG7 GNG7 ENSSBOP00000002626 ENSSBOP00000002626 GNG5 GNG5 GNG11 GNG11 P2RX7 P2RX7 REEP2 REEP2 PDE2A PDE2A ENSSBOP00000038725 ENSSBOP00000038725 PPP2R5E PPP2R5E PTGIR PTGIR KCNMA1 KCNMA1 GNB1 GNB1 PPP2R5B PPP2R5B ATP2A2 ATP2A2 SRI SRI GNG4 GNG4 NOS1 NOS1 ENSSBOP00000002132 ENSSBOP00000002132 STIM1 STIM1 TRPC7 TRPC7 ENSSBOP00000001789 ENSSBOP00000001789 APOB APOB TRPC3 TRPC3 PPP2R1B PPP2R1B PDE1A PDE1A ATP2A1 ATP2A1 P2RX6 P2RX6 PRKG1 PRKG1 FGR FGR ENSSBOP00000034678 ENSSBOP00000034678 PPP2R5D PPP2R5D ORAI2 ORAI2 REEP4 REEP4 SLC8A2 SLC8A2 PRKG2 PRKG2 ENSSBOP00000033458 ENSSBOP00000033458 ATP2B3 ATP2B3 GNAS GNAS P2RX3 P2RX3 PPP2CB PPP2CB GNG8 GNG8 PPP2R5A PPP2R5A GNB5 GNB5 GNGT1 GNGT1 ENSSBOP00000028846 ENSSBOP00000028846 PPP2R1A PPP2R1A GNGT2 GNGT2 GNG13 GNG13 P2RX5 P2RX5 PDE10A PDE10A PLA2G4A PLA2G4A NOS2 NOS2 ENSSBOP00000025229 ENSSBOP00000025229 GNB4 GNB4 ORAI1 ORAI1 LRP8 LRP8 SLC8A3 SLC8A3 GNG2 GNG2 ENSSBOP00000023365 ENSSBOP00000023365 P2RX4 P2RX4 MAPK14 MAPK14 GUCY1A1 GUCY1A1 ITPR2 ITPR2 REEP3 REEP3 ENSSBOP00000021534 ENSSBOP00000021534 PDE9A PDE9A PDE11A PDE11A PPP2R5C PPP2R5C KCNMB1 KCNMB1 GNB2 GNB2 ATP2A3 ATP2A3 ENSSBOP00000018110 ENSSBOP00000018110 ORAI3 ORAI3 PECAM1 PECAM1 P2RX1 P2RX1 PAFAH2 PAFAH2 MRVI1 MRVI1 KCNMB2 KCNMB2 ENSSBOP00000014200 ENSSBOP00000014200 PDE1B PDE1B ENSSBOP00000013998 ENSSBOP00000013998 PTPN6 PTPN6 GNB3 GNB3 GNG12 GNG12 ENSSBOP00000013067 ENSSBOP00000013067 ATP2B4 ATP2B4 PDE5A PDE5A ITPR1 ITPR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
ENSSBOP00000010982Phosphodiesterase. (679 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2673 aa)
ENSSBOP00000010565Uncharacterized protein. (106 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (388 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
ENSSBOP00000007060PDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family. (710 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (646 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (890 aa)
ENSSBOP00000005799Uncharacterized protein. (285 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (636 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ENSSBOP00000002626Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
REEP2Receptor expression-enhancing protein. (254 aa)
PDE2APhosphodiesterase. (920 aa)
ENSSBOP00000038725Phosphodiesterase. (766 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (472 aa)
PTGIRProstaglandin I2 receptor. (386 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1267 aa)
GNB1G protein subunit beta 1. (340 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1036 aa)
SRISorcin. (238 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
ENSSBOP00000002132XRCC1_N domain-containing protein. (141 aa)
STIM1Stromal interaction molecule 1. (716 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (865 aa)
ENSSBOP00000001789Uncharacterized protein. (192 aa)
APOBApolipoprotein B. (4562 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (921 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (695 aa)
PDE1APhosphodiesterase. (545 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (949 aa)
P2RX6P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (362 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
FGRTyrosine-protein kinase. (529 aa)
ENSSBOP00000034678PDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family. (720 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (666 aa)
ORAI2ORAI calcium release-activated calcium modulator 2. (261 aa)
REEP4Receptor expression-enhancing protein. (257 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (810 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
ENSSBOP00000033458Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
GNASGNAS complex locus. (897 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
PPP2CBSerine/threonine-protein phosphatase. (275 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
GNB5G protein subunit beta 5. (357 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ENSSBOP00000028846Uncharacterized protein. (3219 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG13Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
P2RX5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (502 aa)
PDE10APhosphodiesterase. (789 aa)
PLA2G4APhospholipase A2. (655 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1161 aa)
ENSSBOP00000025229Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (61 aa)
GNB4G protein subunit beta 4. (340 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (205 aa)
LRP8LDL receptor related protein 8. (825 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (928 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
ENSSBOP00000023365Uncharacterized protein; Belongs to the transient receptor (TC 1.A.4) family. (886 aa)
P2RX4Purinergic receptor P2X 4. (343 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
REEP3Receptor expression-enhancing protein. (266 aa)
ENSSBOP00000021534PDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family. (734 aa)
PDE9APhosphodiesterase. (609 aa)
PDE11APhosphodiesterase. (910 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (579 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa)
GNB2G protein subunit beta 2. (383 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1086 aa)
ENSSBOP00000018110Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ORAI3ORAI calcium release-activated calcium modulator 3. (295 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (655 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
PAFAH2Platelet-activating factor acetylhydrolase. (399 aa)
MRVI1Murine retrovirus integration site 1 homolog. (929 aa)
KCNMB2KcnmB2_inactiv domain-containing protein. (235 aa)
ENSSBOP00000014200SER_THR_PHOSPHATASE domain-containing protein. (282 aa)
PDE1BPhosphodiesterase. (536 aa)
ENSSBOP00000013998Uncharacterized protein. (241 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
GNB3G protein subunit beta 3. (340 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ENSSBOP00000013067Serine/threonine-protein phosphatase. (332 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
PDE5APhosphodiesterase. (873 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2747 aa)
Your Current Organism:
Saimiri boliviensis
NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis
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