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| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (441 aa) |
| | ENSSBOP00000020808 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa) |
| | PSMB8 | Proteasome subunit beta. (308 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (534 aa) |
| | ENSSBOP00000020952 | Ubiquitin-like domain-containing protein. (140 aa) |
| | IL36RN | Interleukin-1. (155 aa) |
| | ENSSBOP00000021340 | Uncharacterized protein; Belongs to the SKP1 family. (163 aa) |
| | NFKB2 | Nuclear factor kappa B subunit 2. (877 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (494 aa) |
| | S100B | S_100 domain-containing protein; Belongs to the S-100 family. (93 aa) |
| | ENSSBOP00000022060 | VWFA domain-containing protein. (373 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (391 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | ENSSBOP00000022344 | Uncharacterized protein. (217 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | ENSSBOP00000023516 | CCHC NOA-type domain-containing protein. (292 aa) |
| | CARD16 | Caspase recruitment domain family member 16. (175 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (526 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (537 aa) |
| | PTPN20 | Protein tyrosine phosphatase non-receptor type 20. (430 aa) |
| | LRRC31 | Leucine rich repeat containing 31. (552 aa) |
| | LRRC74B | Leucine rich repeat containing 74B. (313 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | USP14 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (492 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (541 aa) |
| | ENSSBOP00000025824 | Uncharacterized protein; Belongs to the SKP1 family. (158 aa) |
| | IL1F10 | Interleukin-1. (152 aa) |
| | IL36B | Interleukin 36 beta. (157 aa) |
| | LRRC71 | Leucine rich repeat containing 71. (559 aa) |
| | TOLLIP | Toll interacting protein. (242 aa) |
| | PSMA7 | Proteasome endopeptidase complex. (251 aa) |
| | S100A12 | S100 calcium binding protein A12; Belongs to the S-100 family. (92 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | MAP3K3 | Uncharacterized protein. (657 aa) |
| | PSMB5 | Proteasome subunit beta. (283 aa) |
| | APP | Amyloid beta precursor protein. (767 aa) |
| | LRRC45 | Leucine rich repeat containing 45. (670 aa) |
| | VWC2 | Von Willebrand factor C domain containing 2. (325 aa) |
| | ENSSBOP00000028579 | PCI domain-containing protein. (402 aa) |
| | CTSG | Cathepsin G; Belongs to the peptidase S1 family. (266 aa) |
| | IL1R2 | Interleukin 1 receptor type 2. (404 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | PSMB10 | Proteasome subunit beta 10. (302 aa) |
| | PSMA6 | Proteasome subunit alpha type. (246 aa) |
| | ENSSBOP00000029669 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (169 aa) |
| | MFSD1 | Major facilitator superfamily domain containing 1. (471 aa) |
| | ENSSBOP00000029926 | AAA domain-containing protein; Belongs to the AAA ATPase family. (430 aa) |
| | ALPK1 | Alpha kinase 1. (1262 aa) |
| | NLRX1 | NLR family member X1. (975 aa) |
| | LRRC34 | Leucine rich repeat containing 34. (452 aa) |
| | IRAK3 | Interleukin 1 receptor associated kinase 3. (590 aa) |
| | PSMD7 | MPN domain-containing protein. (324 aa) |
| | NKIRAS2 | NFKB inhibitor interacting Ras like 2. (239 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (272 aa) |
| | PSME2 | Proteasome activator subunit 2. (239 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (953 aa) |
| | IL1RAP | Interleukin 1 receptor accessory protein. (687 aa) |
| | ENSSBOP00000033458 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa) |
| | ENSSBOP00000033593 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (88 aa) |
| | ENSSBOP00000033692 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (141 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | IL1RL1 | Interleukin 1 receptor like 1. (328 aa) |
| | IL18BP | Interleukin 18 binding protein. (197 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (440 aa) |
| | IL36G | Interleukin-1. (169 aa) |
| | TONSL | Tonsoku like, DNA repair protein. (1379 aa) |
| | ENSSBOP00000034799 | PCI domain-containing protein. (484 aa) |
| | ENSSBOP00000034838 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (215 aa) |
| | NKIRAS1 | NFKB inhibitor interacting Ras like 1. (160 aa) |
| | ENSSBOP00000035130 | Ubiquitin-like domain-containing protein. (135 aa) |
| | ENSSBOP00000035224 | Ubiquitin-like domain-containing protein. (65 aa) |
| | ENSSBOP00000035298 | Proteasome subunit alpha type. (224 aa) |
| | ENSSBOP00000035335 | AAA domain-containing protein; Belongs to the AAA ATPase family. (395 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (406 aa) |
| | PSMA1 | Proteasome endopeptidase complex. (189 aa) |
| | PTPN13 | Protein tyrosine phosphatase non-receptor type 13. (2493 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) |
| | PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (416 aa) |
| | BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (590 aa) |
| | ENSSBOP00000036975 | PROTEASOME_ALPHA_1 domain-containing protein. (233 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (384 aa) |
| | PSMD9 | PDZ domain-containing protein. (223 aa) |
| | ENSSBOP00000037817 | Proteasome subunit alpha type. (221 aa) |
| | STAT3 | Signal transducer and activator of transcription. (721 aa) |
| | ENSSBOP00000038285 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (130 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | PTPN12 | Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (779 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (520 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (350 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (156 aa) |
| | KHNYN | KH and NYN domain containing. (770 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa) |
| | ENSSBOP00000040660 | Uncharacterized protein. (215 aa) |
| | PTPN4 | Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (942 aa) |
| | ENSSBOP00000020408 | Uncharacterized protein; Belongs to the AAA ATPase family. (360 aa) |
| | IL18R1 | Interleukin 18 receptor 1. (539 aa) |
| | NLRC5 | NLR family CARD domain containing 5. (1868 aa) |
| | ENSSBOP00000019567 | Proteasome subunit beta. (223 aa) |
| | ENSSBOP00000019452 | Ubiquitin-like domain-containing protein. (135 aa) |
| | ENSSBOP00000019441 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (231 aa) |
| | MAP3K8 | Mitogen-activated protein kinase kinase kinase 8. (467 aa) |
| | NLRP13 | NLR family pyrin domain containing 13. (1043 aa) |
| | MAP3K2 | Mitogen-activated protein kinase kinase kinase 2. (619 aa) |
| | LRRC14 | Leucine rich repeat containing 14. (493 aa) |
| | ENSSBOP00000017299 | Uncharacterized protein. (226 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (403 aa) |
| | IL13 | Interleukin 13. (145 aa) |
| | ENSSBOP00000016917 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (120 aa) |
| | ENSSBOP00000016736 | AAA domain-containing protein. (399 aa) |
| | PSME3 | Proteasome activator subunit 3. (265 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) |
| | PSMB6 | Proteasome subunit beta. (240 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (271 aa) |
| | PSMA4 | Proteasome subunit alpha type. (284 aa) |
| | IL1RL2 | Interleukin 1 receptor like 2. (575 aa) |
| | SQSTM1 | Sequestosome 1. (439 aa) |
| | CA6-2 | Uncharacterized protein. (229 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1040 aa) |
| | ENSSBOP00000015041 | Proteasome subunit alpha type. (192 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (949 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (760 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa) |
| | MAP3K20 | Mitogen-activated protein kinase kinase kinase 20. (800 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (808 aa) |
| | ENSSBOP00000013998 | Uncharacterized protein. (241 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) |
| | PTPN21 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1095 aa) |
| | PSMC1 | AAA domain-containing protein; Belongs to the AAA ATPase family. (448 aa) |
| | IL18RAP | Interleukin 18 receptor accessory protein. (594 aa) |
| | ENSSBOP00000013349 | Uncharacterized protein. (210 aa) |
| | RBX1 | Ring-box 1. (105 aa) |
| | IRAK2 | Interleukin 1 receptor associated kinase 2. (626 aa) |
| | IL1RAPL1 | Interleukin 1 receptor accessory protein like 1. (696 aa) |
| | FBXW11 | F-box and WD repeat domain containing 11. (542 aa) |
| | ENSSBOP00000012837 | Uncharacterized protein. (132 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | PSMA8 | Proteasome subunit alpha type. (250 aa) |
| | PSMB3 | Proteasome subunit beta. (208 aa) |
| | ALOX5 | Arachidonate 5-lipoxygenase. (674 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (750 aa) |
| | ENSSBOP00000011888 | Proteasome subunit beta. (198 aa) |
| | NFKBIA | NFKB inhibitor alpha. (310 aa) |
| | PSMD5 | Proteasome 26S subunit, non-ATPase 5. (508 aa) |
| | PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (364 aa) |
| | PTPN5 | Protein tyrosine phosphatase non-receptor type 5. (565 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | LRRC74A | Leucine rich repeat containing 74A. (482 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa) |
| | PSME4 | Uncharacterized protein. (1826 aa) |
| | NLRP6 | NLR family pyrin domain containing 6. (895 aa) |
| | CASP1 | Uncharacterized protein; Belongs to the peptidase C14A family. (404 aa) |
| | ENSSBOP00000009685 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (140 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | PELI2 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (407 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | ENSSBOP00000008293 | Uncharacterized protein. (89 aa) |
| | ENSSBOP00000008066 | Proteasome endopeptidase complex. (151 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (472 aa) |
| | TAB3 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa) |
| | ENSSBOP00000006404 | Proteasome subunit alpha type. (244 aa) |
| | ENSSBOP00000006203 | Ubiquitin-like domain-containing protein. (156 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (507 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | NLRP9 | NLR family pyrin domain containing 9. (934 aa) |
| | N4BP1 | NEDD4 binding protein 1. (810 aa) |
| | ENSSBOP00000005799 | Uncharacterized protein. (285 aa) |
| | ENSSBOP00000005716 | Uncharacterized protein; Belongs to the SKP1 family. (137 aa) |
| | PTPN18 | Protein tyrosine phosphatase non-receptor type 18. (452 aa) |
| | ENSSBOP00000005508 | Uncharacterized protein. (1842 aa) |
| | ENSSBOP00000005230 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (170 aa) |
| | SIGIRR | Single Ig and TIR domain containing. (362 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (152 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (652 aa) |
| | ENSSBOP00000004094 | Uncharacterized protein. (180 aa) |
| | ENSSBOP00000003994 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (127 aa) |
| | ENSSBOP00000003929 | Uncharacterized protein. (203 aa) |
| | ENSSBOP00000003922 | Protein kinase domain-containing protein. (688 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (395 aa) |
| | ENSSBOP00000003537 | Ubiquitin-like domain-containing protein. (155 aa) |
| | ENSSBOP00000003417 | Uncharacterized protein. (200 aa) |
| | IL1R1 | Interleukin 1 receptor type 1. (569 aa) |
| | PELI3 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (469 aa) |
| | ENSSBOP00000002616 | Uncharacterized protein. (206 aa) |
| | IL36A | Interleukin-1. (114 aa) |
| | PSME1 | Proteasome activator subunit 1. (250 aa) |
| | ENSSBOP00000001789 | Uncharacterized protein. (192 aa) |
| | PSMB11 | Proteasome subunit beta. (304 aa) |
| | IL1RN | Interleukin-1. (179 aa) |
| | SKP1 | Uncharacterized protein; Belongs to the SKP1 family. (163 aa) |
| | PTPN14 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1187 aa) |
| | PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa) |
| | ENSSBOP00000001426 | Uncharacterized protein. (375 aa) |
| | PTPN7 | Protein tyrosine phosphatase non-receptor type 7. (488 aa) |
| | ENSSBOP00000001388 | Uncharacterized protein. (161 aa) |
| | ENSSBOP00000001375 | Uncharacterized protein. (341 aa) |
| | PTPN9 | Protein tyrosine phosphatase non-receptor type 9. (556 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (359 aa) |
| | IL37 | Interleukin-1. (221 aa) |
| | IL33 | Interleukin 33. (270 aa) |
| | PTPN23 | Protein tyrosine phosphatase non-receptor type 23. (1659 aa) |
| | GSDMD | Gasdermin D. (491 aa) |
| | ENSSBOP00000000486 | AAA domain-containing protein; Belongs to the AAA ATPase family. (216 aa) |
| | ENSSBOP00000000409 | AAA domain-containing protein. (370 aa) |
| | PELI1 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa) |
