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PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) | ||||
ENSSBOP00000040634 | CAF1C_H4-bd domain-containing protein. (121 aa) | ||||
ENSSBOP00000040527 | WD_REPEATS_REGION domain-containing protein. (413 aa) | ||||
RPS27A | Ubiquitin-like domain-containing protein. (156 aa) | ||||
PSMD8 | Proteasome 26S subunit, non-ATPase 8. (350 aa) | ||||
RRAGD | Ras related GTP binding D. (399 aa) | ||||
SNAI2 | Snail family transcriptional repressor 2. (268 aa) | ||||
LAMTOR5 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (156 aa) | ||||
LAMTOR2 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (125 aa) | ||||
ENSSBOP00000039148 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (392 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
PSMB2 | Proteasome subunit beta. (201 aa) | ||||
NPTXR | Neuronal pentraxin receptor. (438 aa) | ||||
RHEBL1 | RHEB like 1. (183 aa) | ||||
RHEB | Uncharacterized protein. (492 aa) | ||||
ENSSBOP00000037817 | Proteasome subunit alpha type. (221 aa) | ||||
PSMD9 | PDZ domain-containing protein. (223 aa) | ||||
SNAI1 | Snail family transcriptional repressor 1. (265 aa) | ||||
ENSSBOP00000037087 | Hist_deacetyl domain-containing protein. (226 aa) | ||||
ENSSBOP00000036975 | PROTEASOME_ALPHA_1 domain-containing protein. (233 aa) | ||||
MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) | ||||
MKRN2 | Makorin ring finger protein 2. (416 aa) | ||||
PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (416 aa) | ||||
PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) | ||||
PSMA1 | Proteasome endopeptidase complex. (189 aa) | ||||
ENSSBOP00000035658 | Uncharacterized protein. (102 aa) | ||||
ENSSBOP00000035335 | AAA domain-containing protein; Belongs to the AAA ATPase family. (395 aa) | ||||
ENSSBOP00000035298 | Proteasome subunit alpha type. (224 aa) | ||||
ENSSBOP00000035224 | Ubiquitin-like domain-containing protein. (65 aa) | ||||
RBBP7 | RB binding protein 7, chromatin remodeling factor. (446 aa) | ||||
ENSSBOP00000035130 | Ubiquitin-like domain-containing protein. (135 aa) | ||||
CBX8 | Chromobox 8. (414 aa) | ||||
ENSSBOP00000034838 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (215 aa) | ||||
ENSSBOP00000034799 | PCI domain-containing protein. (484 aa) | ||||
EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa) | ||||
CRYBB3 | Crystallin beta B3; Belongs to the beta/gamma-crystallin family. (211 aa) | ||||
ENSSBOP00000033331 | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (164 aa) | ||||
XIAP | X-linked inhibitor of apoptosis. (497 aa) | ||||
TXNDC11 | Thioredoxin domain containing 11. (868 aa) | ||||
CBX6 | Chromobox 6. (422 aa) | ||||
PSME2 | Proteasome activator subunit 2. (239 aa) | ||||
ENSSBOP00000032291 | RING-type domain-containing protein. (363 aa) | ||||
REST | RE1 silencing transcription factor. (1110 aa) | ||||
LAMTOR1 | Uncharacterized protein. (161 aa) | ||||
NPTX1 | Neuronal pentraxin 1. (388 aa) | ||||
LY6G5B | Uncharacterized protein. (298 aa) | ||||
PSMD7 | MPN domain-containing protein. (324 aa) | ||||
ENSSBOP00000030724 | WD_REPEATS_REGION domain-containing protein. (433 aa) | ||||
RNF141 | Ring finger protein 141. (230 aa) | ||||
ENSSBOP00000005508 | Uncharacterized protein. (1842 aa) | ||||
PSMA2 | Proteasome subunit alpha type. (234 aa) | ||||
ENSSBOP00000006203 | Ubiquitin-like domain-containing protein. (156 aa) | ||||
ENSSBOP00000006404 | Proteasome subunit alpha type. (244 aa) | ||||
MTA2 | Metastasis associated 1 family member 2. (668 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (486 aa) | ||||
MECOM | MDS1 and EVI1 complex locus. (1230 aa) | ||||
EED | Embryonic ectoderm development. (466 aa) | ||||
PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (472 aa) | ||||
CHD3 | Chromodomain helicase DNA binding protein 3. (2000 aa) | ||||
AGO1 | Argonaute RISC component 1; Belongs to the argonaute family. (857 aa) | ||||
ENSSBOP00000008066 | Proteasome endopeptidase complex. (151 aa) | ||||
ENSSBOP00000008293 | Uncharacterized protein. (89 aa) | ||||
PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) | ||||
CHD4 | Uncharacterized protein. (1881 aa) | ||||
PHC1 | Polyhomeotic homolog 1. (1021 aa) | ||||
LAMTOR3 | Uncharacterized protein. (124 aa) | ||||
PSMA3 | Proteasome subunit alpha type. (255 aa) | ||||
RING1 | Ring finger protein 1. (406 aa) | ||||
PSME4 | Uncharacterized protein. (1826 aa) | ||||
PSMB9 | Proteasome subunit beta. (219 aa) | ||||
PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (364 aa) | ||||
NEDD4 | NEDD4 E3 ubiquitin protein ligase. (1319 aa) | ||||
ENSSBOP00000011053 | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (249 aa) | ||||
TNKS2 | Poly [ADP-ribose] polymerase. (1166 aa) | ||||
PSMD5 | Proteasome 26S subunit, non-ATPase 5. (508 aa) | ||||
ENSSBOP00000011888 | Proteasome subunit beta. (198 aa) | ||||
ENSSBOP00000012173 | WD_REPEATS_REGION domain-containing protein. (341 aa) | ||||
PSMB3 | Proteasome subunit beta. (208 aa) | ||||
PSMA8 | Proteasome subunit alpha type. (250 aa) | ||||
PREX2 | Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2. (1606 aa) | ||||
ENSSBOP00000013349 | Uncharacterized protein. (210 aa) | ||||
ENSSBOP00000013362 | Uncharacterized protein. (447 aa) | ||||
SCML2 | Scm polycomb group protein like 2. (701 aa) | ||||
PSMC1 | AAA domain-containing protein; Belongs to the AAA ATPase family. (448 aa) | ||||
PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) | ||||
PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (808 aa) | ||||
ENSSBOP00000014361 | Uncharacterized protein. (282 aa) | ||||
MKRN1 | Makorin ring finger protein 1. (377 aa) | ||||
UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa) | ||||
TRIM7 | Tripartite motif containing 7. (319 aa) | ||||
PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (949 aa) | ||||
ENSSBOP00000015041 | Proteasome subunit alpha type. (192 aa) | ||||
CA6-2 | Uncharacterized protein. (229 aa) | ||||
FRK | Tyrosine-protein kinase. (505 aa) | ||||
PSMA4 | Proteasome subunit alpha type. (284 aa) | ||||
HDAC3 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa) | ||||
PSMF1 | Proteasome inhibitor subunit 1. (271 aa) | ||||
PSMB6 | Proteasome subunit beta. (240 aa) | ||||
PSME3 | Proteasome activator subunit 3. (265 aa) | ||||
BMI1 | RING-type domain-containing protein. (326 aa) | ||||
ENSSBOP00000030215 | Uncharacterized protein. (406 aa) | ||||
MBD3 | Methyl-CpG binding domain protein 3. (272 aa) | ||||
ENSSBOP00000029926 | AAA domain-containing protein; Belongs to the AAA ATPase family. (430 aa) | ||||
PSMA6 | Proteasome subunit alpha type. (246 aa) | ||||
PSMB10 | Proteasome subunit beta 10. (302 aa) | ||||
USP7 | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1112 aa) | ||||
RRAGC | Ras related GTP binding C. (333 aa) | ||||
GUF1 | Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (669 aa) | ||||
GATAD2B | GATA zinc finger domain containing 2B. (601 aa) | ||||
ENSSBOP00000028579 | PCI domain-containing protein. (402 aa) | ||||
MAPK3 | Mitogen-activated protein kinase. (322 aa) | ||||
MTA3 | Metastasis associated 1 family member 3. (621 aa) | ||||
PSMB5 | Proteasome subunit beta. (283 aa) | ||||
MTA1 | Metastasis associated 1. (697 aa) | ||||
PSMA5 | Proteasome subunit alpha type. (241 aa) | ||||
CBX4 | Chromobox 4. (507 aa) | ||||
AGO3 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa) | ||||
PSMA7 | Proteasome endopeptidase complex. (251 aa) | ||||
SALL4 | Spalt like transcription factor 4. (1053 aa) | ||||
ATN1 | Atrophin 1. (1183 aa) | ||||
TNRC6B | Trinucleotide repeat containing adaptor 6B. (1818 aa) | ||||
HDAC7 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1000 aa) | ||||
RNF146 | Uncharacterized protein. (359 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
ENSSBOP00000026258 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (379 aa) | ||||
GATAD2A | GATA zinc finger domain containing 2A. (634 aa) | ||||
PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) | ||||
PSMB1 | Proteasome subunit beta. (241 aa) | ||||
NPTX2 | Neuronal pentraxin 2. (494 aa) | ||||
ENSSBOP00000025422 | Chromo domain-containing protein. (503 aa) | ||||
RERE | Arginine-glutamic acid dipeptide repeats. (1535 aa) | ||||
KIAA1671 | KIAA1671. (1794 aa) | ||||
SALL2 | Spalt like transcription factor 2. (1009 aa) | ||||
MAPK1 | Mitogen-activated protein kinase 1. (305 aa) | ||||
MAF1 | Repressor of RNA polymerase III transcription MAF1; Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA. Belongs to the MAF1 family. (258 aa) | ||||
PSMB7 | Proteasome subunit beta. (277 aa) | ||||
RCOR1 | REST corepressor 1. (464 aa) | ||||
OTUD3 | OTU deubiquitinase 3. (337 aa) | ||||
PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) | ||||
ENSSBOP00000022373 | Uncharacterized protein. (483 aa) | ||||
ENSSBOP00000022344 | Uncharacterized protein. (217 aa) | ||||
PSMD4 | Proteasome 26S subunit, non-ATPase 4. (391 aa) | ||||
ENSSBOP00000022060 | VWFA domain-containing protein. (373 aa) | ||||
AIRE | Autoimmune regulator. (530 aa) | ||||
ENSSBOP00000021549 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (421 aa) | ||||
NR2E1 | Nuclear receptor subfamily 2 group E member 1. (421 aa) | ||||
ENSSBOP00000020952 | Ubiquitin-like domain-containing protein. (140 aa) | ||||
SLC38A9 | Solute carrier family 38 member 9. (563 aa) | ||||
PSMD3 | Proteasome 26S subunit, non-ATPase 3. (534 aa) | ||||
PSMB8 | Proteasome subunit beta. (308 aa) | ||||
PSME1 | Proteasome activator subunit 1. (250 aa) | ||||
USP13 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (826 aa) | ||||
ENSSBOP00000020408 | Uncharacterized protein; Belongs to the AAA ATPase family. (360 aa) | ||||
RPTOR | Regulatory associated protein of MTOR complex 1. (1335 aa) | ||||
AGO4 | Argonaute RISC component 4; Belongs to the argonaute family. (855 aa) | ||||
HDAC5 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1088 aa) | ||||
CSNK2A2 | Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (337 aa) | ||||
ENSSBOP00000019567 | Proteasome subunit beta. (223 aa) | ||||
TRIM27 | Tripartite motif containing 27. (440 aa) | ||||
SNAI3 | Snail family transcriptional repressor 3. (282 aa) | ||||
EZH1 | Enhancer of zeste 1 polycomb repressive complex 2 subunit. (751 aa) | ||||
ENSSBOP00000019452 | Ubiquitin-like domain-containing protein. (135 aa) | ||||
CBX7 | Chromobox 7. (251 aa) | ||||
ENSSBOP00000019441 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (231 aa) | ||||
OTUD4 | OTU deubiquitinase 4. (1102 aa) | ||||
SUZ12 | SUZ12 polycomb repressive complex 2 subunit. (542 aa) | ||||
HDAC2 | Hist_deacetyl domain-containing protein. (314 aa) | ||||
MLST8 | MTOR associated protein, LST8 homolog. (326 aa) | ||||
CRYGN | Crystallin gamma N; Belongs to the beta/gamma-crystallin family. (147 aa) | ||||
EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa) | ||||
RBBP4 | CAF1C_H4-bd domain-containing protein. (134 aa) | ||||
HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) | ||||
ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (507 aa) | ||||
KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (883 aa) | ||||
ENSSBOP00000017299 | Uncharacterized protein. (226 aa) | ||||
SCML1 | Scm polycomb group protein like 1. (319 aa) | ||||
ENSSBOP00000016736 | AAA domain-containing protein. (399 aa) | ||||
STUB1 | STIP1 homology and U-box containing protein 1. (250 aa) | ||||
RNF2 | Ring finger protein 2. (336 aa) | ||||
LAMTOR4 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (99 aa) | ||||
ENSSBOP00000000409 | AAA domain-containing protein. (370 aa) | ||||
ENSSBOP00000000486 | AAA domain-containing protein; Belongs to the AAA ATPase family. (216 aa) | ||||
CHD5 | Chromodomain helicase DNA binding protein 5. (1908 aa) | ||||
PSMD6 | Proteasome 26S subunit, non-ATPase 6. (441 aa) | ||||
ENSSBOP00000000870 | Uncharacterized protein. (183 aa) | ||||
MOV10 | Mov10 RISC complex RNA helicase. (1003 aa) | ||||
ENSSBOP00000001426 | Uncharacterized protein. (375 aa) | ||||
PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa) | ||||
PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa) | ||||
RRAGA | Uncharacterized protein. (313 aa) | ||||
PSMB11 | Proteasome subunit beta. (304 aa) | ||||
ENSSBOP00000001749 | CAF1C_H4-bd domain-containing protein. (96 aa) | ||||
ENSSBOP00000001989 | RING-type domain-containing protein. (262 aa) | ||||
CSNK2A1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (385 aa) | ||||
ENSSBOP00000002041 | Uncharacterized protein. (199 aa) | ||||
PHC3 | Polyhomeotic homolog 3. (983 aa) | ||||
RRAGB | Ras related GTP binding B. (374 aa) | ||||
PHC2 | Polyhomeotic homolog 2. (852 aa) | ||||
PML | Promyelocytic leukemia. (806 aa) | ||||
ENSSBOP00000003417 | Uncharacterized protein. (200 aa) | ||||
ENSSBOP00000003537 | Ubiquitin-like domain-containing protein. (155 aa) | ||||
PSMD13 | Proteasome 26S subunit, non-ATPase 13. (395 aa) | ||||
ENSSBOP00000004204 | WD_REPEATS_REGION domain-containing protein. (379 aa) | ||||
TNKS | Poly [ADP-ribose] polymerase. (1325 aa) | ||||
ENSSBOP00000004490 | Uncharacterized protein. (359 aa) | ||||
SCMH1 | Scm polycomb group protein homolog 1. (659 aa) | ||||
ENSSBOP00000004997 | Uncharacterized protein. (147 aa) | ||||
WWP2 | E3 ubiquitin-protein ligase. (870 aa) | ||||
AGO2 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (874 aa) |