STRINGSTRING
PSMB4 PSMB4 ENSSBOP00000040634 ENSSBOP00000040634 ENSSBOP00000040527 ENSSBOP00000040527 RPS27A RPS27A PSMD8 PSMD8 RRAGD RRAGD SNAI2 SNAI2 LAMTOR5 LAMTOR5 LAMTOR2 LAMTOR2 ENSSBOP00000039148 ENSSBOP00000039148 AKT2 AKT2 PSMB2 PSMB2 NPTXR NPTXR RHEBL1 RHEBL1 RHEB RHEB ENSSBOP00000037817 ENSSBOP00000037817 PSMD9 PSMD9 SNAI1 SNAI1 ENSSBOP00000037087 ENSSBOP00000037087 ENSSBOP00000036975 ENSSBOP00000036975 MTOR MTOR MKRN2 MKRN2 PSMC5 PSMC5 PSMC4 PSMC4 PSMA1 PSMA1 ENSSBOP00000035658 ENSSBOP00000035658 ENSSBOP00000035335 ENSSBOP00000035335 ENSSBOP00000035298 ENSSBOP00000035298 ENSSBOP00000035224 ENSSBOP00000035224 RBBP7 RBBP7 ENSSBOP00000035130 ENSSBOP00000035130 CBX8 CBX8 ENSSBOP00000034838 ENSSBOP00000034838 ENSSBOP00000034799 ENSSBOP00000034799 EGR1 EGR1 CRYBB3 CRYBB3 ENSSBOP00000033331 ENSSBOP00000033331 XIAP XIAP TXNDC11 TXNDC11 CBX6 CBX6 PSME2 PSME2 ENSSBOP00000032291 ENSSBOP00000032291 REST REST LAMTOR1 LAMTOR1 NPTX1 NPTX1 LY6G5B LY6G5B PSMD7 PSMD7 ENSSBOP00000030724 ENSSBOP00000030724 RNF141 RNF141 ENSSBOP00000005508 ENSSBOP00000005508 PSMA2 PSMA2 ENSSBOP00000006203 ENSSBOP00000006203 ENSSBOP00000006404 ENSSBOP00000006404 MTA2 MTA2 AKT1 AKT1 MECOM MECOM EED EED PSMC2 PSMC2 CHD3 CHD3 AGO1 AGO1 ENSSBOP00000008066 ENSSBOP00000008066 ENSSBOP00000008293 ENSSBOP00000008293 PSMD10 PSMD10 CHD4 CHD4 PHC1 PHC1 LAMTOR3 LAMTOR3 PSMA3 PSMA3 RING1 RING1 PSME4 PSME4 PSMB9 PSMB9 PSMC6 PSMC6 NEDD4 NEDD4 ENSSBOP00000011053 ENSSBOP00000011053 TNKS2 TNKS2 PSMD5 PSMD5 ENSSBOP00000011888 ENSSBOP00000011888 ENSSBOP00000012173 ENSSBOP00000012173 PSMB3 PSMB3 PSMA8 PSMA8 PREX2 PREX2 ENSSBOP00000013349 ENSSBOP00000013349 ENSSBOP00000013362 ENSSBOP00000013362 SCML2 SCML2 PSMC1 PSMC1 PSMD14 PSMD14 PSMD2 PSMD2 ENSSBOP00000014361 ENSSBOP00000014361 MKRN1 MKRN1 UBA52 UBA52 TRIM7 TRIM7 PSMD1 PSMD1 ENSSBOP00000015041 ENSSBOP00000015041 CA6-2 CA6-2 FRK FRK PSMA4 PSMA4 HDAC3 HDAC3 PSMF1 PSMF1 PSMB6 PSMB6 PSME3 PSME3 BMI1 BMI1 ENSSBOP00000030215 ENSSBOP00000030215 MBD3 MBD3 ENSSBOP00000029926 ENSSBOP00000029926 PSMA6 PSMA6 PSMB10 PSMB10 USP7 USP7 RRAGC RRAGC GUF1 GUF1 GATAD2B GATAD2B ENSSBOP00000028579 ENSSBOP00000028579 MAPK3 MAPK3 MTA3 MTA3 PSMB5 PSMB5 MTA1 MTA1 PSMA5 PSMA5 CBX4 CBX4 AGO3 AGO3 PSMA7 PSMA7 SALL4 SALL4 ATN1 ATN1 TNRC6B TNRC6B HDAC7 HDAC7 RNF146 RNF146 AKT3 AKT3 ENSSBOP00000026258 ENSSBOP00000026258 GATAD2A GATAD2A PTEN PTEN PSMB1 PSMB1 NPTX2 NPTX2 ENSSBOP00000025422 ENSSBOP00000025422 RERE RERE KIAA1671 KIAA1671 SALL2 SALL2 MAPK1 MAPK1 MAF1 MAF1 PSMB7 PSMB7 RCOR1 RCOR1 OTUD3 OTUD3 PSMD11 PSMD11 ENSSBOP00000022373 ENSSBOP00000022373 ENSSBOP00000022344 ENSSBOP00000022344 PSMD4 PSMD4 ENSSBOP00000022060 ENSSBOP00000022060 AIRE AIRE ENSSBOP00000021549 ENSSBOP00000021549 NR2E1 NR2E1 ENSSBOP00000020952 ENSSBOP00000020952 SLC38A9 SLC38A9 PSMD3 PSMD3 PSMB8 PSMB8 PSME1 PSME1 USP13 USP13 ENSSBOP00000020408 ENSSBOP00000020408 RPTOR RPTOR AGO4 AGO4 HDAC5 HDAC5 CSNK2A2 CSNK2A2 ENSSBOP00000019567 ENSSBOP00000019567 TRIM27 TRIM27 SNAI3 SNAI3 EZH1 EZH1 ENSSBOP00000019452 ENSSBOP00000019452 CBX7 CBX7 ENSSBOP00000019441 ENSSBOP00000019441 OTUD4 OTUD4 SUZ12 SUZ12 HDAC2 HDAC2 MLST8 MLST8 CRYGN CRYGN EZH2 EZH2 RBBP4 RBBP4 HDAC1 HDAC1 ATF2 ATF2 KDM1A KDM1A ENSSBOP00000017299 ENSSBOP00000017299 SCML1 SCML1 ENSSBOP00000016736 ENSSBOP00000016736 STUB1 STUB1 RNF2 RNF2 LAMTOR4 LAMTOR4 ENSSBOP00000000409 ENSSBOP00000000409 ENSSBOP00000000486 ENSSBOP00000000486 CHD5 CHD5 PSMD6 PSMD6 ENSSBOP00000000870 ENSSBOP00000000870 MOV10 MOV10 ENSSBOP00000001426 ENSSBOP00000001426 PSMC3 PSMC3 PPARG PPARG RRAGA RRAGA PSMB11 PSMB11 ENSSBOP00000001749 ENSSBOP00000001749 ENSSBOP00000001989 ENSSBOP00000001989 CSNK2A1 CSNK2A1 ENSSBOP00000002041 ENSSBOP00000002041 PHC3 PHC3 RRAGB RRAGB PHC2 PHC2 PML PML ENSSBOP00000003417 ENSSBOP00000003417 ENSSBOP00000003537 ENSSBOP00000003537 PSMD13 PSMD13 ENSSBOP00000004204 ENSSBOP00000004204 TNKS TNKS ENSSBOP00000004490 ENSSBOP00000004490 SCMH1 SCMH1 ENSSBOP00000004997 ENSSBOP00000004997 WWP2 WWP2 AGO2 AGO2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
ENSSBOP00000040634CAF1C_H4-bd domain-containing protein. (121 aa)
ENSSBOP00000040527WD_REPEATS_REGION domain-containing protein. (413 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
RRAGDRas related GTP binding D. (399 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
LAMTOR5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (156 aa)
LAMTOR2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (125 aa)
ENSSBOP00000039148Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (392 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PSMB2Proteasome subunit beta. (201 aa)
NPTXRNeuronal pentraxin receptor. (438 aa)
RHEBL1RHEB like 1. (183 aa)
RHEBUncharacterized protein. (492 aa)
ENSSBOP00000037817Proteasome subunit alpha type. (221 aa)
PSMD9PDZ domain-containing protein. (223 aa)
SNAI1Snail family transcriptional repressor 1. (265 aa)
ENSSBOP00000037087Hist_deacetyl domain-containing protein. (226 aa)
ENSSBOP00000036975PROTEASOME_ALPHA_1 domain-containing protein. (233 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
MKRN2Makorin ring finger protein 2. (416 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (416 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMA1Proteasome endopeptidase complex. (189 aa)
ENSSBOP00000035658Uncharacterized protein. (102 aa)
ENSSBOP00000035335AAA domain-containing protein; Belongs to the AAA ATPase family. (395 aa)
ENSSBOP00000035298Proteasome subunit alpha type. (224 aa)
ENSSBOP00000035224Ubiquitin-like domain-containing protein. (65 aa)
RBBP7RB binding protein 7, chromatin remodeling factor. (446 aa)
ENSSBOP00000035130Ubiquitin-like domain-containing protein. (135 aa)
CBX8Chromobox 8. (414 aa)
ENSSBOP00000034838Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (215 aa)
ENSSBOP00000034799PCI domain-containing protein. (484 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa)
CRYBB3Crystallin beta B3; Belongs to the beta/gamma-crystallin family. (211 aa)
ENSSBOP00000033331Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (164 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
TXNDC11Thioredoxin domain containing 11. (868 aa)
CBX6Chromobox 6. (422 aa)
PSME2Proteasome activator subunit 2. (239 aa)
ENSSBOP00000032291RING-type domain-containing protein. (363 aa)
RESTRE1 silencing transcription factor. (1110 aa)
LAMTOR1Uncharacterized protein. (161 aa)
NPTX1Neuronal pentraxin 1. (388 aa)
LY6G5BUncharacterized protein. (298 aa)
PSMD7MPN domain-containing protein. (324 aa)
ENSSBOP00000030724WD_REPEATS_REGION domain-containing protein. (433 aa)
RNF141Ring finger protein 141. (230 aa)
ENSSBOP00000005508Uncharacterized protein. (1842 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
ENSSBOP00000006203Ubiquitin-like domain-containing protein. (156 aa)
ENSSBOP00000006404Proteasome subunit alpha type. (244 aa)
MTA2Metastasis associated 1 family member 2. (668 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (486 aa)
MECOMMDS1 and EVI1 complex locus. (1230 aa)
EEDEmbryonic ectoderm development. (466 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (472 aa)
CHD3Chromodomain helicase DNA binding protein 3. (2000 aa)
AGO1Argonaute RISC component 1; Belongs to the argonaute family. (857 aa)
ENSSBOP00000008066Proteasome endopeptidase complex. (151 aa)
ENSSBOP00000008293Uncharacterized protein. (89 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
CHD4Uncharacterized protein. (1881 aa)
PHC1Polyhomeotic homolog 1. (1021 aa)
LAMTOR3Uncharacterized protein. (124 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
RING1Ring finger protein 1. (406 aa)
PSME4Uncharacterized protein. (1826 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (364 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1319 aa)
ENSSBOP00000011053Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (249 aa)
TNKS2Poly [ADP-ribose] polymerase. (1166 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (508 aa)
ENSSBOP00000011888Proteasome subunit beta. (198 aa)
ENSSBOP00000012173WD_REPEATS_REGION domain-containing protein. (341 aa)
PSMB3Proteasome subunit beta. (208 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
PREX2Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2. (1606 aa)
ENSSBOP00000013349Uncharacterized protein. (210 aa)
ENSSBOP00000013362Uncharacterized protein. (447 aa)
SCML2Scm polycomb group protein like 2. (701 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (448 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (808 aa)
ENSSBOP00000014361Uncharacterized protein. (282 aa)
MKRN1Makorin ring finger protein 1. (377 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
TRIM7Tripartite motif containing 7. (319 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (949 aa)
ENSSBOP00000015041Proteasome subunit alpha type. (192 aa)
CA6-2Uncharacterized protein. (229 aa)
FRKTyrosine-protein kinase. (505 aa)
PSMA4Proteasome subunit alpha type. (284 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PSMB6Proteasome subunit beta. (240 aa)
PSME3Proteasome activator subunit 3. (265 aa)
BMI1RING-type domain-containing protein. (326 aa)
ENSSBOP00000030215Uncharacterized protein. (406 aa)
MBD3Methyl-CpG binding domain protein 3. (272 aa)
ENSSBOP00000029926AAA domain-containing protein; Belongs to the AAA ATPase family. (430 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMB10Proteasome subunit beta 10. (302 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1112 aa)
RRAGCRas related GTP binding C. (333 aa)
GUF1Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (669 aa)
GATAD2BGATA zinc finger domain containing 2B. (601 aa)
ENSSBOP00000028579PCI domain-containing protein. (402 aa)
MAPK3Mitogen-activated protein kinase. (322 aa)
MTA3Metastasis associated 1 family member 3. (621 aa)
PSMB5Proteasome subunit beta. (283 aa)
MTA1Metastasis associated 1. (697 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
CBX4Chromobox 4. (507 aa)
AGO3Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa)
PSMA7Proteasome endopeptidase complex. (251 aa)
SALL4Spalt like transcription factor 4. (1053 aa)
ATN1Atrophin 1. (1183 aa)
TNRC6BTrinucleotide repeat containing adaptor 6B. (1818 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1000 aa)
RNF146Uncharacterized protein. (359 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ENSSBOP00000026258Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (379 aa)
GATAD2AGATA zinc finger domain containing 2A. (634 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
PSMB1Proteasome subunit beta. (241 aa)
NPTX2Neuronal pentraxin 2. (494 aa)
ENSSBOP00000025422Chromo domain-containing protein. (503 aa)
REREArginine-glutamic acid dipeptide repeats. (1535 aa)
KIAA1671KIAA1671. (1794 aa)
SALL2Spalt like transcription factor 2. (1009 aa)
MAPK1Mitogen-activated protein kinase 1. (305 aa)
MAF1Repressor of RNA polymerase III transcription MAF1; Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA. Belongs to the MAF1 family. (258 aa)
PSMB7Proteasome subunit beta. (277 aa)
RCOR1REST corepressor 1. (464 aa)
OTUD3OTU deubiquitinase 3. (337 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
ENSSBOP00000022373Uncharacterized protein. (483 aa)
ENSSBOP00000022344Uncharacterized protein. (217 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (391 aa)
ENSSBOP00000022060VWFA domain-containing protein. (373 aa)
AIREAutoimmune regulator. (530 aa)
ENSSBOP00000021549Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (421 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (421 aa)
ENSSBOP00000020952Ubiquitin-like domain-containing protein. (140 aa)
SLC38A9Solute carrier family 38 member 9. (563 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
PSMB8Proteasome subunit beta. (308 aa)
PSME1Proteasome activator subunit 1. (250 aa)
USP13Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (826 aa)
ENSSBOP00000020408Uncharacterized protein; Belongs to the AAA ATPase family. (360 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1335 aa)
AGO4Argonaute RISC component 4; Belongs to the argonaute family. (855 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1088 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (337 aa)
ENSSBOP00000019567Proteasome subunit beta. (223 aa)
TRIM27Tripartite motif containing 27. (440 aa)
SNAI3Snail family transcriptional repressor 3. (282 aa)
EZH1Enhancer of zeste 1 polycomb repressive complex 2 subunit. (751 aa)
ENSSBOP00000019452Ubiquitin-like domain-containing protein. (135 aa)
CBX7Chromobox 7. (251 aa)
ENSSBOP00000019441Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (231 aa)
OTUD4OTU deubiquitinase 4. (1102 aa)
SUZ12SUZ12 polycomb repressive complex 2 subunit. (542 aa)
HDAC2Hist_deacetyl domain-containing protein. (314 aa)
MLST8MTOR associated protein, LST8 homolog. (326 aa)
CRYGNCrystallin gamma N; Belongs to the beta/gamma-crystallin family. (147 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa)
RBBP4CAF1C_H4-bd domain-containing protein. (134 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (507 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (883 aa)
ENSSBOP00000017299Uncharacterized protein. (226 aa)
SCML1Scm polycomb group protein like 1. (319 aa)
ENSSBOP00000016736AAA domain-containing protein. (399 aa)
STUB1STIP1 homology and U-box containing protein 1. (250 aa)
RNF2Ring finger protein 2. (336 aa)
LAMTOR4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (99 aa)
ENSSBOP00000000409AAA domain-containing protein. (370 aa)
ENSSBOP00000000486AAA domain-containing protein; Belongs to the AAA ATPase family. (216 aa)
CHD5Chromodomain helicase DNA binding protein 5. (1908 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (441 aa)
ENSSBOP00000000870Uncharacterized protein. (183 aa)
MOV10Mov10 RISC complex RNA helicase. (1003 aa)
ENSSBOP00000001426Uncharacterized protein. (375 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
RRAGAUncharacterized protein. (313 aa)
PSMB11Proteasome subunit beta. (304 aa)
ENSSBOP00000001749CAF1C_H4-bd domain-containing protein. (96 aa)
ENSSBOP00000001989RING-type domain-containing protein. (262 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (385 aa)
ENSSBOP00000002041Uncharacterized protein. (199 aa)
PHC3Polyhomeotic homolog 3. (983 aa)
RRAGBRas related GTP binding B. (374 aa)
PHC2Polyhomeotic homolog 2. (852 aa)
PMLPromyelocytic leukemia. (806 aa)
ENSSBOP00000003417Uncharacterized protein. (200 aa)
ENSSBOP00000003537Ubiquitin-like domain-containing protein. (155 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (395 aa)
ENSSBOP00000004204WD_REPEATS_REGION domain-containing protein. (379 aa)
TNKSPoly [ADP-ribose] polymerase. (1325 aa)
ENSSBOP00000004490Uncharacterized protein. (359 aa)
SCMH1Scm polycomb group protein homolog 1. (659 aa)
ENSSBOP00000004997Uncharacterized protein. (147 aa)
WWP2E3 ubiquitin-protein ligase. (870 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (874 aa)
Your Current Organism:
Saimiri boliviensis
NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis
Server load: low (18%) [HD]