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| | CDC25A | Cell division cycle 25A. (422 aa) |
| | ENSSBOP00000016736 | AAA domain-containing protein. (399 aa) |
| | PSME3 | Proteasome activator subunit 3. (265 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (448 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) |
| | PSMB6 | Proteasome subunit beta. (240 aa) |
| | TM4SF19 | Uncharacterized protein. (205 aa) |
| | MCM9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1139 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (271 aa) |
| | ENSSBOP00000015845 | Uncharacterized protein. (360 aa) |
| | PSMA4 | Proteasome subunit alpha type. (284 aa) |
| | ENSSBOP00000015560 | SMC hinge domain-containing protein. (1083 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa) |
| | ENSSBOP00000015121 | Uncharacterized protein. (71 aa) |
| | CA6-2 | Uncharacterized protein. (229 aa) |
| | ENSSBOP00000015041 | Proteasome subunit alpha type. (192 aa) |
| | PDS5B | PDS5 cohesin associated factor B. (1404 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (949 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa) |
| | ENSSBOP00000014362 | Protein kinase domain-containing protein. (281 aa) |
| | ENSSBOP00000014262 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (86 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (808 aa) |
| | FZR1 | Fizzy and cell division cycle 20 related 1. (496 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) |
| | PSMC1 | AAA domain-containing protein; Belongs to the AAA ATPase family. (448 aa) |
| | ENSSBOP00000013349 | Uncharacterized protein. (210 aa) |
| | ENSSBOP00000013296 | Protein kinase domain-containing protein. (283 aa) |
| | RBX1 | Ring-box 1. (105 aa) |
| | ENSSBOP00000013190 | Uncharacterized protein. (198 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | PSMA8 | Proteasome subunit alpha type. (250 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa) |
| | ESCO2 | Establishment of sister chromatid cohesion N-acetyltransferase 2. (511 aa) |
| | PSMB3 | Proteasome subunit beta. (208 aa) |
| | ENSSBOP00000011888 | Proteasome subunit beta. (198 aa) |
| | ENSSBOP00000011574 | Uncharacterized protein. (112 aa) |
| | PSMD5 | Proteasome 26S subunit, non-ATPase 5. (508 aa) |
| | PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (364 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | GINS1 | GINS complex subunit 1. (196 aa) |
| | ENSSBOP00000010326 | MCM domain-containing protein; Belongs to the MCM family. (846 aa) |
| | PSME4 | Uncharacterized protein. (1826 aa) |
| | ENSSBOP00000010190 | Uncharacterized protein. (155 aa) |
| | ENSSBOP00000010168 | RING-type domain-containing protein. (84 aa) |
| | RAD21L1 | RAD21 cohesin complex component like 1. (556 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | FAM89A | Uncharacterized protein. (77 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | ENSSBOP00000008293 | Uncharacterized protein. (89 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (813 aa) |
| | ENSSBOP00000008066 | Proteasome endopeptidase complex. (151 aa) |
| | ENSSBOP00000008061 | Uncharacterized protein. (187 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (472 aa) |
| | MNAT1 | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (847 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | ENSSBOP00000006618 | DOC domain-containing protein. (79 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (486 aa) |
| | POLE3 | DNA polymerase epsilon 3, accessory subunit. (178 aa) |
| | LIN9 | Lin-9 DREAM MuvB core complex component. (570 aa) |
| | KIAA2012 | KIAA2012. (1158 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | GINS3 | GINS complex subunit 3. (216 aa) |
| | PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (416 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | ENSSBOP00000036013 | DNA ligase. (504 aa) |
| | PSMA1 | Proteasome endopeptidase complex. (189 aa) |
| | ENSSBOP00000035656 | Uncharacterized protein. (70 aa) |
| | POLD2 | DNA polymerase delta 2, accessory subunit. (479 aa) |
| | ENSSBOP00000035335 | AAA domain-containing protein; Belongs to the AAA ATPase family. (395 aa) |
| | ENSSBOP00000035298 | Proteasome subunit alpha type. (224 aa) |
| | ENSSBOP00000035224 | Ubiquitin-like domain-containing protein. (65 aa) |
| | ENSSBOP00000035130 | Ubiquitin-like domain-containing protein. (135 aa) |
| | ENSSBOP00000034838 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (215 aa) |
| | POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (520 aa) |
| | ENSSBOP00000034799 | PCI domain-containing protein. (484 aa) |
| | CDC27 | Cell division cycle 27. (824 aa) |
| | PRIM2 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (505 aa) |
| | SMC1A | Structural maintenance of chromosomes protein. (1233 aa) |
| | WEE1 | WEE1 G2 checkpoint kinase. (432 aa) |
| | POLA2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (573 aa) |
| | UBE2D1 | Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (148 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2268 aa) |
| | ORC5 | Origin recognition complex subunit 5. (404 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | PSME2 | Proteasome activator subunit 2. (239 aa) |
| | ENSSBOP00000032117 | Uncharacterized protein. (165 aa) |
| | MAX | MYC associated factor X. (160 aa) |
| | PSMD7 | MPN domain-containing protein. (324 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | UBE2S | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (222 aa) |
| | CDC16 | Cell division cycle 16. (625 aa) |
| | ENSSBOP00000029926 | AAA domain-containing protein; Belongs to the AAA ATPase family. (430 aa) |
| | PSMA6 | Proteasome subunit alpha type. (246 aa) |
| | PSMB10 | Proteasome subunit beta 10. (302 aa) |
| | CKS2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (59 aa) |
| | RFC5 | Replication factor C subunit 5. (340 aa) |
| | ENSSBOP00000028878 | Uncharacterized protein. (111 aa) |
| | RAD21 | Uncharacterized protein. (631 aa) |
| | ENSSBOP00000028579 | PCI domain-containing protein. (402 aa) |
| | PSMB5 | Proteasome subunit beta. (283 aa) |
| | ENSSBOP00000028194 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (223 aa) |
| | TCERG1L | Transcription elongation regulator 1 like. (472 aa) |
| | WAPL | WAPL cohesin release factor. (1261 aa) |
| | LIN54 | Lin-54 DREAM MuvB core complex component. (749 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (578 aa) |
| | ENSSBOP00000027650 | Uncharacterized protein. (134 aa) |
| | STAG2 | Stromal antigen 2. (1179 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | POLD4 | Uncharacterized protein. (107 aa) |
| | TFDP2 | Transcription factor. (447 aa) |
| | PSMA7 | Proteasome endopeptidase complex. (251 aa) |
| | TFDP1 | Transcription factor. (411 aa) |
| | ENSSBOP00000027147 | Protein kinase domain-containing protein. (395 aa) |
| | ANAPC2 | Anaphase promoting complex subunit 2; Belongs to the cullin family. (806 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | ENSSBOP00000026166 | SMC_N domain-containing protein. (573 aa) |
| | GINS2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa) |
| | ANAPC7 | Anaphase promoting complex subunit 7. (565 aa) |
| | ENSSBOP00000025824 | Uncharacterized protein; Belongs to the SKP1 family. (158 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | POLD1 | DNA polymerase. (1088 aa) |
| | E2F1 | E2F transcription factor 1. (352 aa) |
| | E2F4 | E2F transcription factor 4. (415 aa) |
| | GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (244 aa) |
| | ENSSBOP00000024179 | Uncharacterized protein. (86 aa) |
| | ESCO1 | Establishment of sister chromatid cohesion N-acetyltransferase 1. (840 aa) |
| | ENSSBOP00000023935 | Uncharacterized protein. (78 aa) |
| | ANAPC10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (406 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) |
| | UBE2E1 | Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa) |
| | UBE2C | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) |
| | RB1 | RB transcriptional corepressor 1. (926 aa) |
| | ANAPC5 | Anaphase promoting complex subunit 5. (742 aa) |
| | ENSSBOP00000022344 | Uncharacterized protein. (217 aa) |
| | TM7SF3 | Transmembrane 7 superfamily member 3. (570 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (391 aa) |
| | ENSSBOP00000022060 | VWFA domain-containing protein. (373 aa) |
| | ENSSBOP00000021788 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (80 aa) |
| | WEE2 | Wee1-like protein kinase. (571 aa) |
| | ENSSBOP00000021340 | Uncharacterized protein; Belongs to the SKP1 family. (163 aa) |
| | ENSSBOP00000020952 | Ubiquitin-like domain-containing protein. (140 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (534 aa) |
| | PSMB8 | Proteasome subunit beta. (308 aa) |
| | PSME1 | Proteasome activator subunit 1. (250 aa) |
| | RCBTB2 | RCC1 and BTB domain containing protein 2. (556 aa) |
| | ENSSBOP00000020408 | Uncharacterized protein; Belongs to the AAA ATPase family. (360 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (859 aa) |
| | ENSSBOP00000019963 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (76 aa) |
| | RFC4 | Replication factor C subunit 4. (319 aa) |
| | LIN52 | Lin-52 DREAM MuvB core complex component. (116 aa) |
| | FAM89B | Family with sequence similarity 89 member B. (119 aa) |
| | GMNN | Geminin DNA replication inhibitor. (204 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | PSMD9 | PDZ domain-containing protein. (223 aa) |
| | ENSSBOP00000037817 | Proteasome subunit alpha type. (221 aa) |
| | ENSSBOP00000038165 | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (304 aa) |
| | CDK4 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa) |
| | CDC25B | Cell division cycle 25B. (580 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | ENSSBOP00000038765 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (282 aa) |
| | RBL2 | RB transcriptional corepressor like 2. (1138 aa) |
| | ANAPC15 | Anaphase promoting complex subunit 15. (177 aa) |
| | CDK2 | Cyclin dependent kinase 2. (289 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (734 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (350 aa) |
| | PRIM1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (366 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (156 aa) |
| | CDT1 | Chromatin licensing and DNA replication factor 1. (475 aa) |
| | LIG1 | DNA ligase. (942 aa) |
| | ENSSBOP00000040024 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (154 aa) |
| | ENSSBOP00000006404 | Proteasome subunit alpha type. (244 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | ENSSBOP00000005904 | F-box domain-containing protein. (424 aa) |
| | POLA1 | DNA polymerase. (1474 aa) |
| | CDK7 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (289 aa) |
| | ENSSBOP00000005716 | Uncharacterized protein; Belongs to the SKP1 family. (137 aa) |
| | ENSSBOP00000005508 | Uncharacterized protein. (1842 aa) |
| | RPA3 | Replication protein A3. (121 aa) |
| | CCNH | Cyclin H; Belongs to the cyclin family. (329 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (158 aa) |
| | FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | CDC45 | Cell division cycle 45. (594 aa) |
| | ORC6 | Origin recognition complex subunit 6. (252 aa) |
| | RCBTB1 | RCC1 and BTB domain containing protein 1. (531 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (395 aa) |
| | ENSSBOP00000003537 | Ubiquitin-like domain-containing protein. (155 aa) |
| | ENSSBOP00000003417 | Uncharacterized protein. (200 aa) |
| | RFC1 | Replication factor C subunit 1. (1148 aa) |
| | ENSSBOP00000003115 | Uncharacterized protein. (131 aa) |
| | E2F5 | E2F transcription factor 5. (322 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (500 aa) |
| | MEIOB | Meiosis specific with OB-fold. (468 aa) |
| | PSMB11 | Proteasome subunit beta. (304 aa) |
| | ENSSBOP00000001560 | Uncharacterized protein. (573 aa) |
| | SKP1 | Uncharacterized protein; Belongs to the SKP1 family. (163 aa) |
| | PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa) |
| | ENSSBOP00000001426 | Uncharacterized protein. (375 aa) |
| | ENSSBOP00000001143 | Uncharacterized protein. (133 aa) |
| | CABLES1 | Cdk5 and Abl enzyme substrate 1. (527 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (441 aa) |
| | RFC3 | Replication factor C subunit 3. (356 aa) |
| | ENSSBOP00000000486 | AAA domain-containing protein; Belongs to the AAA ATPase family. (216 aa) |
| | CDC23 | Cell division cycle 23. (597 aa) |
| | ENSSBOP00000000409 | AAA domain-containing protein. (370 aa) |
| | ENSSBOP00000036975 | PROTEASOME_ALPHA_1 domain-containing protein. (233 aa) |
| | ENSSBOP00000006203 | Ubiquitin-like domain-containing protein. (156 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (828 aa) |
| | POLE4 | DNA polymerase epsilon 4, accessory subunit. (118 aa) |
| | POLD3 | DNA polymerase delta 3, accessory subunit. (466 aa) |
| | ENSSBOP00000019567 | Proteasome subunit beta. (223 aa) |
| | ENSSBOP00000019452 | Ubiquitin-like domain-containing protein. (135 aa) |
| | ENSSBOP00000019441 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (231 aa) |
| | LIN37 | Uncharacterized protein. (236 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (856 aa) |
| | ANAPC1 | Anaphase promoting complex subunit 1. (1863 aa) |
| | ENSSBOP00000018831 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (201 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (904 aa) |
| | ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (808 aa) |
| | PDS5A | PDS5 cohesin associated factor A. (1307 aa) |
| | ORC2 | Uncharacterized protein. (159 aa) |
| | ORC3 | Origin recognition complex subunit 3. (711 aa) |
| | CKS1B | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | STAG1 | Stromal antigen 1. (1259 aa) |
| | CDCA5 | Cell division cycle associated 5. (270 aa) |
| | PTK6 | Tyrosine-protein kinase. (483 aa) |
| | ENSSBOP00000017299 | Uncharacterized protein. (226 aa) |
| | ANAPC16 | Anaphase promoting complex subunit 16. (110 aa) |
