STRINGSTRING
SYT11 SYT11 AAK1 AAK1 NETO1 NETO1 RPS27A RPS27A AP2A2 AP2A2 TACR1 TACR1 ENSSBOP00000040466 ENSSBOP00000040466 UBQLN2 UBQLN2 STON2 STON2 ENSSBOP00000035389 ENSSBOP00000035389 ENSSBOP00000035224 ENSSBOP00000035224 BTC BTC CD3G CD3G AREG AREG SLC18A3 SLC18A3 CHRM2 CHRM2 APOB APOB TGFA TGFA TOR1A TOR1A AP2M1 AP2M1 PGBD4 PGBD4 COPS7A COPS7A ENSSBOP00000003537 ENSSBOP00000003537 COPS5 COPS5 REPS2 REPS2 HGS HGS SYT2 SYT2 SH3GL1 SH3GL1 KIAA0319 KIAA0319 ENSSBOP00000005954 ENSSBOP00000005954 ENSSBOP00000006203 ENSSBOP00000006203 UBL7 UBL7 SCARB2 SCARB2 UBQLN1 UBQLN1 ENSSBOP00000007293 ENSSBOP00000007293 ADRB2 ADRB2 WNT5A WNT5A FCHO1 FCHO1 VAMP3 VAMP3 COPS6 COPS6 ENSSBOP00000009071 ENSSBOP00000009071 CLTA CLTA EPS15 EPS15 UBQLN4 UBQLN4 CBL CBL ENSSBOP00000010142 ENSSBOP00000010142 NECAP1 NECAP1 EPN2 EPN2 AP2A1 AP2A1 TOR1B TOR1B EREG EREG NECAP2 NECAP2 SH3GL3 SH3GL3 PICALM PICALM GPS1 GPS1 VAMP5 VAMP5 DVL2 DVL2 UBA52 UBA52 COPS2 COPS2 IGF2R IGF2R ARRB2 ARRB2 ENSSBOP00000035130 ENSSBOP00000035130 GRB2 GRB2 AGFG1 AGFG1 COPS7B COPS7B COPS4 COPS4 NEDD8 NEDD8 SYT1 SYT1 ENSSBOP00000034105 ENSSBOP00000034105 ENSSBOP00000033923 ENSSBOP00000033923 ENSSBOP00000033753 ENSSBOP00000033753 SGIP1 SGIP1 AP2S1 AP2S1 SH3GL2 SH3GL2 SYT9 SYT9 LRP2 LRP2 CLHC1 CLHC1 IL7R IL7R AVPR2 AVPR2 COPS8 COPS8 ARR3 ARR3 ZFYVE1 ZFYVE1 VAMP8 VAMP8 VAMP2 VAMP2 CD3D CD3D FCHO2 FCHO2 SLC2A8 SLC2A8 COPS3 COPS3 MCTP1 MCTP1 VAMP7 VAMP7 ENSSBOP00000019452 ENSSBOP00000019452 M6PR M6PR STAM STAM EPS15L1 EPS15L1 FZD4 FZD4 REPS1 REPS1 ITSN1 ITSN1 BMP2K BMP2K ENSSBOP00000020952 ENSSBOP00000020952 LMBRD2 LMBRD2 STAM2 STAM2 ARRB1 ARRB1 ENSSBOP00000022506 ENSSBOP00000022506 ENSSBOP00000022667 ENSSBOP00000022667 GRK2 GRK2 EGFR EGFR ENTHD1 ENTHD1 SYT8 SYT8 LDLR LDLR AGTR1 AGTR1 MCTP2 MCTP2 CLTB CLTB ENSSBOP00000025905 ENSSBOP00000025905 SYT4 SYT4 NETO2 NETO2 SNAP91 SNAP91 VAMP4 VAMP4 TF TF CLPB CLPB CLTCL1 CLTCL1 ZFYVE19 ZFYVE19 KIAA0319L KIAA0319L CD4 CD4 HBEGF HBEGF ENSSBOP00000028846 ENSSBOP00000028846 PPP1R42 PPP1R42 AP2B1 AP2B1 ITSN2 ITSN2 EPN3 EPN3 EPN1 EPN1 EPGN EPGN EGF EGF CFTR CFTR TFRC TFRC STON1 STON1 CLTC CLTC AGFG2 AGFG2 LDLRAP1 LDLRAP1 DAB2 DAB2 GRK3 GRK3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SYT11Synaptotagmin 11. (431 aa)
AAK1AP2 associated kinase 1. (965 aa)
NETO1Neuropilin and tolloid like 1. (533 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (969 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
ENSSBOP00000040466Uncharacterized protein. (704 aa)
UBQLN2Ubiquilin 2. (624 aa)
STON2Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family. (934 aa)
ENSSBOP00000035389Ubiquitin-like domain-containing protein. (73 aa)
ENSSBOP00000035224Ubiquitin-like domain-containing protein. (65 aa)
BTCBetacellulin. (203 aa)
CD3GCD3g molecule. (181 aa)
AREGAmphiregulin. (275 aa)
SLC18A3Solute carrier family 18 member A3. (532 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (482 aa)
APOBApolipoprotein B. (4562 aa)
TGFATransforming growth factor alpha. (187 aa)
TOR1ATorsin. (332 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (435 aa)
PGBD4PiggyBac transposable element derived 4. (585 aa)
COPS7ACOP9 signalosome subunit 7A. (234 aa)
ENSSBOP00000003537Ubiquitin-like domain-containing protein. (155 aa)
COPS5COP9 signalosome subunit 5. (334 aa)
REPS2RALBP1 associated Eps domain containing 2. (634 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (692 aa)
SYT2Synaptotagmin 2. (421 aa)
SH3GL1Uncharacterized protein. (367 aa)
KIAA0319KIAA0319. (1073 aa)
ENSSBOP00000005954Uncharacterized protein. (209 aa)
ENSSBOP00000006203Ubiquitin-like domain-containing protein. (156 aa)
UBL7Ubiquitin like 7. (370 aa)
SCARB2Scavenger receptor class B member 2; Belongs to the CD36 family. (478 aa)
UBQLN1Ubiquilin 1. (537 aa)
ENSSBOP00000007293SH3 domain-containing protein. (384 aa)
ADRB2Adrenoceptor beta 2. (399 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
FCHO1FCH domain only 1. (858 aa)
VAMP3Vesicle associated membrane protein 3. (122 aa)
COPS6COP9 signalosome subunit 6. (344 aa)
ENSSBOP00000009071Ubiquitin-like domain-containing protein. (81 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa)
EPS15Epidermal growth factor receptor pathway substrate 15. (891 aa)
UBQLN4Ubiquilin 4. (597 aa)
CBLCbl proto-oncogene. (748 aa)
ENSSBOP00000010142Longin domain-containing protein; Belongs to the synaptobrevin family. (212 aa)
NECAP1NECAP endocytosis associated 1. (275 aa)
EPN2Epsin 2. (641 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (967 aa)
TOR1BTorsin family 1 member B. (303 aa)
EREGEpiregulin. (164 aa)
NECAP2NECAP endocytosis associated 2. (271 aa)
SH3GL3SH3 domain containing GRB2 like 3, endophilin A3. (355 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (653 aa)
GPS1G protein pathway suppressor 1. (500 aa)
VAMP5Vesicle associated membrane protein 5. (115 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
COPS2COP9 signalosome subunit 2. (450 aa)
IGF2RInsulin like growth factor 2 receptor. (2472 aa)
ARRB2Arrestin beta 2. (469 aa)
ENSSBOP00000035130Ubiquitin-like domain-containing protein. (135 aa)
GRB2Growth factor receptor bound protein 2. (184 aa)
AGFG1ArfGAP with FG repeats 1. (533 aa)
COPS7BCOP9 signalosome subunit 7B. (277 aa)
COPS4COP9 signalosome subunit 4. (368 aa)
NEDD8Ubiquitin-like domain-containing protein. (81 aa)
SYT1Synaptotagmin 1. (419 aa)
ENSSBOP00000034105AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (458 aa)
ENSSBOP00000033923Uncharacterized protein. (354 aa)
ENSSBOP00000033753CSN7a_helixI domain-containing protein. (281 aa)
SGIP1SH3 domain GRB2 like endophilin interacting protein 1. (859 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (157 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (349 aa)
SYT9Synaptotagmin 9. (491 aa)
LRP2LDL receptor related protein 2. (4618 aa)
CLHC1Clathrin heavy chain linker domain-containing protein 1. (527 aa)
IL7RInterleukin 7 receptor. (459 aa)
AVPR2Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (371 aa)
COPS8COP9 signalosome subunit 8. (209 aa)
ARR3Arrestin 3. (386 aa)
ZFYVE1Zinc finger FYVE-type containing 1. (789 aa)
VAMP8Vesicle associated membrane protein 8. (100 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (118 aa)
CD3DCD3d molecule. (171 aa)
FCHO2FCH domain only 2. (799 aa)
SLC2A8Solute carrier family 2 member 8; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (477 aa)
COPS3COP9 signalosome subunit 3. (326 aa)
MCTP1Multiple C2 and transmembrane domain containing 1. (931 aa)
VAMP7Vesicle associated membrane protein 7; Belongs to the synaptobrevin family. (263 aa)
ENSSBOP00000019452Ubiquitin-like domain-containing protein. (135 aa)
M6PRMannose-6-phosphate receptor, cation dependent. (278 aa)
STAMSignal transducing adaptor molecule. (541 aa)
EPS15L1Epidermal growth factor receptor pathway substrate 15 like 1. (910 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (539 aa)
REPS1RALBP1 associated Eps domain containing 1. (773 aa)
ITSN1Intersectin 1. (1690 aa)
BMP2KBMP2 inducible kinase. (1053 aa)
ENSSBOP00000020952Ubiquitin-like domain-containing protein. (140 aa)
LMBRD2LMBR1 domain containing 2. (695 aa)
STAM2Uncharacterized protein. (525 aa)
ARRB1Arrestin beta 1. (413 aa)
ENSSBOP00000022506Uncharacterized protein. (442 aa)
ENSSBOP00000022667DUF1681 domain-containing protein. (249 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (692 aa)
EGFRReceptor protein-tyrosine kinase. (1196 aa)
ENTHD1ENTH domain containing 1. (609 aa)
SYT8Synaptotagmin 8. (393 aa)
LDLRLow density lipoprotein receptor. (569 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (388 aa)
MCTP2Multiple C2 and transmembrane domain containing 2. (885 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (181 aa)
ENSSBOP00000025905Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (102 aa)
SYT4Synaptotagmin 4. (425 aa)
NETO2Neuropilin and tolloid like 2. (522 aa)
SNAP91Synaptosome associated protein 91. (907 aa)
VAMP4Vesicle associated membrane protein 4. (141 aa)
TFTransferrin; Belongs to the transferrin family. (700 aa)
CLPBClpB homolog, mitochondrial AAA ATPase chaperonin. (707 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1642 aa)
ZFYVE19Zinc finger FYVE-type containing 19. (462 aa)
KIAA0319LKIAA0319 like. (1049 aa)
CD4CD4 molecule. (457 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
ENSSBOP00000028846Uncharacterized protein. (3219 aa)
PPP1R42Protein phosphatase 1 regulatory subunit 42. (309 aa)
AP2B1AP complex subunit beta. (951 aa)
ITSN2Intersectin 2. (1688 aa)
EPN3Epsin 3. (567 aa)
EPN1Epsin 1. (640 aa)
EPGNEpithelial mitogen. (154 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1186 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1481 aa)
TFRCTransferrin receptor. (720 aa)
STON1Stonin-1; May be involved in the endocytic machinery. (735 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1682 aa)
AGFG2ArfGAP with FG repeats 2. (475 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (278 aa)
DAB2DAB adaptor protein 2. (767 aa)
GRK3G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (616 aa)
Your Current Organism:
Saimiri boliviensis
NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis
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