STRINGSTRING
ISL1 ISL1 BDNF BDNF OTX2 OTX2 NES NES WNT1 WNT1 THY1 THY1 PAX6 PAX6 LHX2 LHX2 RPE65 RPE65 SIX3 SIX3 CRX CRX POU4F2 POU4F2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ISL1ISL LIM homeobox 1. (349 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (330 aa)
OTX2Orthodenticle homeobox 2. (297 aa)
NESNestin; Belongs to the intermediate filament family. (1414 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
THY1Thy-1 cell surface antigen. (161 aa)
PAX6Paired box 6. (488 aa)
LHX2LIM homeobox 2. (406 aa)
RPE65Retinoid isomerohydrolase RPE65. (533 aa)
SIX3SIX homeobox 3. (329 aa)
CRXCone-rod homeobox. (299 aa)
POU4F2POU domain protein. (408 aa)
Your Current Organism:
Saimiri boliviensis
NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis
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