STRINGSTRING
CERS1 CERS1 DEGS2 DEGS2 NEU2 NEU2 CERK CERK SPHK1 SPHK1 SGPP2 SGPP2 UGCG UGCG PPAP2C PPAP2C PPAP2B PPAP2B GBA GBA KDSR KDSR SMPD3 SMPD3 NEU1 NEU1 CERS4 CERS4 ACER3 ACER3 SGMS1 SGMS1 CERS3 CERS3 ARSA ARSA SGMS2 SGMS2 ENPP7 ENPP7 SMPD1 SMPD1 GALC GALC CERS6 CERS6 SPTLC1 SPTLC1 GLB1 GLB1 ACER1 ACER1 SPTLC3 SPTLC3 GBA2 GBA2 SPTLC2 SPTLC2 PSAP PSAP UGT8 UGT8 ASAH1 ASAH1 DEGS1 DEGS1 SGPL1 SGPL1 SPHK2 SPHK2 ASAH2 ASAH2 NEU3 NEU3 ACER2 ACER2 CERS2 CERS2 SMPD2 SMPD2 NEU4 NEU4 B4GALT6 B4GALT6 GLA GLA GAL3ST1 GAL3ST1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CERS1TLC domain-containing protein. (239 aa)
DEGS2Delta 4-desaturase, sphingolipid 2. (323 aa)
NEU2Neuraminidase 2. (379 aa)
CERKCeramide kinase. (467 aa)
SPHK1Sphingosine kinase 1. (488 aa)
SGPP2Sphingosine-1-phosphate phosphatase 2. (353 aa)
UGCGUDP-glucose ceramide glucosyltransferase. (297 aa)
PPAP2CacidPPc domain-containing protein. (224 aa)
PPAP2BacidPPc domain-containing protein. (311 aa)
GBAGlucosylceramidase. (536 aa)
KDSR3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
NEU1Neuraminidase 1. (414 aa)
CERS4Ceramide synthase 4. (400 aa)
ACER3Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (225 aa)
SGMS1Sphingomyelin synthase 1. (413 aa)
CERS3Ceramide synthase 3. (382 aa)
ARSAArylsulfatase A. (509 aa)
SGMS2Sphingomyelin synthase 2. (365 aa)
ENPP7Ectonucleotide pyrophosphatase/phosphodiesterase 7. (450 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa)
GALCGalactosylceramidase. (685 aa)
CERS6Ceramide synthase 6. (375 aa)
SPTLC1Aminotran_1_2 domain-containing protein. (498 aa)
GLB1Galactosidase beta 1; Belongs to the glycosyl hydrolase 35 family. (583 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa)
SPTLC3Serine palmitoyltransferase long chain base subunit 3. (553 aa)
GBA2Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (923 aa)
SPTLC2Serine palmitoyltransferase long chain base subunit 2. (497 aa)
PSAPProsaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. (524 aa)
UGT8UDP glycosyltransferase 8; Belongs to the UDP-glycosyltransferase family. (541 aa)
ASAH1N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (432 aa)
DEGS1Delta 4-desaturase, sphingolipid 1. (323 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (568 aa)
SPHK2Sphingosine kinase 2. (656 aa)
ASAH2Neutral ceramidase. (778 aa)
NEU3Neuraminidase 3. (461 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
CERS2Ceramide synthase 2. (431 aa)
SMPD2Sphingomyelin phosphodiesterase 2. (422 aa)
NEU4Neuraminidase 4. (491 aa)
B4GALT6Beta-1,4-galactosyltransferase 6. (382 aa)
GLAAlpha-galactosidase. (429 aa)
GAL3ST1Galactose-3-O-sulfotransferase 1. (482 aa)
Your Current Organism:
Saimiri boliviensis
NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.