STRINGSTRING
SEMA3E SEMA3E RND1 RND1 CXCR4 CXCR4 RAC3 RAC3 UNC5D UNC5D PLXNA1 PLXNA1 CFL2 CFL2 RAF1 RAF1 CDK5 CDK5 ENSSBOP00000003528 ENSSBOP00000003528 UNC5C UNC5C SLIT2 SLIT2 PPP3CC PPP3CC LRRC4C LRRC4C MET MET ENSSBOP00000005039 ENSSBOP00000005039 SEMA4A SEMA4A BOC BOC PDK1 PDK1 TRPC6 TRPC6 PIK3CA PIK3CA SSH2 SSH2 EFNB1 EFNB1 UNC5A UNC5A SLIT3 SLIT3 PIK3CB PIK3CB ARHGEF12 ARHGEF12 WNT5A WNT5A PLXNB1 PLXNB1 NRAS NRAS SLIT1 SLIT1 RRAS RRAS RAC2 RAC2 EPHB2 EPHB2 PPP3R1 PPP3R1 PTK2 PTK2 EPHB1 EPHB1 PLXNA4 PLXNA4 NCK2 NCK2 EFNA2 EFNA2 PARD6G PARD6G DPYSL5 DPYSL5 ENSSBOP00000010668 ENSSBOP00000010668 GDF7 GDF7 KRAS KRAS EPHA8 EPHA8 LRRC4 LRRC4 SEMA3F SEMA3F NTN1 NTN1 DPYSL2 DPYSL2 GSK3B GSK3B EPHA5 EPHA5 HRAS HRAS RGMA RGMA NFATC2 NFATC2 NTNG1 NTNG1 ROBO3 ROBO3 BMPR1B BMPR1B TRPC5 TRPC5 SEMA3C SEMA3C ITGB1 ITGB1 RASA1 RASA1 SEMA7A SEMA7A RYK RYK LIMK2 LIMK2 SEMA6C SEMA6C TRPC4 TRPC4 RAC1 RAC1 PLXNB2 PLXNB2 PIK3R3 PIK3R3 PLXNB3 PLXNB3 BMPR2 BMPR2 CAMK2A CAMK2A CDC42 CDC42 TRPC1 TRPC1 EPHA1 EPHA1 PRKCZ PRKCZ CFL1 CFL1 ROCK2 ROCK2 PLCG2 PLCG2 SEMA4C SEMA4C NTN3 NTN3 SEMA4G SEMA4G WNT4 WNT4 UNC5B UNC5B ILK ILK PAK6 PAK6 NFATC4 NFATC4 NFATC3 NFATC3 SEMA6D SEMA6D SEMA5B SEMA5B RHOC RHOC EFNB3 EFNB3 PTCH1 PTCH1 GNAI2 GNAI2 PLCG1 PLCG1 MAPK1 MAPK1 NTN4 NTN4 EPHA6 EPHA6 SRGAP3 SRGAP3 ROBO1 ROBO1 ROBO2 ROBO2 EFNA4 EFNA4 SEMA4B SEMA4B SEMA4D SEMA4D NEO1 NEO1 BMP7 BMP7 PAK5 PAK5 ABL1 ABL1 SRC SRC RHOD RHOD SRGAP1 SRGAP1 GNAI1 GNAI1 SRGAP2 SRGAP2 PPP3CB PPP3CB FES FES NTNG2 NTNG2 SEMA4F SEMA4F CXCL12 CXCL12 PAK4 PAK4 MAPK3 MAPK3 NGEF NGEF SEMA3D SEMA3D EFNB2 EFNB2 FZD3 FZD3 EFNA3 EFNA3 RGS3 RGS3 SEMA3A SEMA3A NRP1 NRP1 SEMA6A SEMA6A ABLIM3 ABLIM3 FYN FYN EPHA7 EPHA7 EPHA4 EPHA4 PARD3 PARD3 PARD6A PARD6A ENSSBOP00000032178 ENSSBOP00000032178 DCC DCC SEMA5A SEMA5A PARD6B PARD6B EPHB6 EPHB6 EPHB4 EPHB4 PLXNA2 PLXNA2 L1CAM L1CAM EPHB3 EPHB3 NCK1 NCK1 PAK2 PAK2 WNT5B WNT5B PPP3CA PPP3CA PIK3R2 PIK3R2 PLXNC1 PLXNC1 ROCK1 ROCK1 SSH3 SSH3 SMO SMO PRKCA PRKCA PLXNA3 PLXNA3 EFNA5 EFNA5 SEMA3B SEMA3B PAK1 PAK1 EFNA1 EFNA1 PIK3R1 PIK3R1 MYL9 MYL9 TRPC3 TRPC3 SSH1 SSH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (774 aa)
RND1Rho family GTPase 1. (232 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (392 aa)
RAC3Rac family small GTPase 3. (311 aa)
UNC5DUnc-5 netrin receptor D. (941 aa)
PLXNA1Plexin A1. (1938 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
ENSSBOP00000003528Uncharacterized protein. (1061 aa)
UNC5CUnc-5 netrin receptor C. (931 aa)
SLIT2Slit guidance ligand 2. (1541 aa)
PPP3CCSerine/threonine-protein phosphatase. (520 aa)
LRRC4CLeucine rich repeat containing 4C. (640 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1406 aa)
ENSSBOP00000005039Uncharacterized protein. (178 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (761 aa)
BOCBOC cell adhesion associated, oncogene regulated. (1115 aa)
PDK1Protein-serine/threonine kinase. (429 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (890 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SSH2Slingshot protein phosphatase 2. (1448 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (346 aa)
UNC5AUnc-5 netrin receptor A. (856 aa)
SLIT3Slit guidance ligand 3. (1530 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1091 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1543 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
PLXNB1Plexin B1. (2137 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
SLIT1Slit guidance ligand 1. (1534 aa)
RRASRAS related. (218 aa)
RAC2Rac family small GTPase 2. (192 aa)
EPHB2EPH receptor B2. (1088 aa)
PPP3R1Uncharacterized protein. (189 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (979 aa)
EPHB1EPH receptor B1. (984 aa)
PLXNA4Plexin A4. (1894 aa)
NCK2Cytoplasmic protein. (380 aa)
EFNA2Ephrin A2; Belongs to the ephrin family. (197 aa)
PARD6GPar-6 family cell polarity regulator gamma. (352 aa)
DPYSL5Dihydropyrimidinase like 5. (564 aa)
ENSSBOP00000010668Uncharacterized protein. (129 aa)
GDF7Growth differentiation factor 7. (363 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
EPHA8EPH receptor A8. (1019 aa)
LRRC4Leucine rich repeat containing 4. (609 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (785 aa)
NTN1Netrin 1. (575 aa)
DPYSL2Dihydropyrimidinase like 2. (662 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
EPHA5EPH receptor A5. (1038 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
RGMARepulsive guidance molecule BMP co-receptor a. (454 aa)
NFATC2Nuclear factor of activated T cells 2. (937 aa)
NTNG1Netrin G1. (539 aa)
ROBO3Roundabout guidance receptor 3. (1383 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (751 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
RASA1RAS p21 protein activator 1. (1049 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (624 aa)
RYKReceptor like tyrosine kinase. (529 aa)
LIMK2LIM domain kinase 2. (638 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (893 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (982 aa)
RAC1Uncharacterized protein. (207 aa)
PLXNB2Plexin B2. (1839 aa)
PIK3R3Uncharacterized protein. (461 aa)
PLXNB3Plexin B3. (1909 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
CDC42Uncharacterized protein. (191 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (800 aa)
EPHA1EPH receptor A1. (972 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (587 aa)
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (175 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1386 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (820 aa)
NTN3Netrin 3. (507 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (844 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (341 aa)
UNC5BUnc-5 netrin receptor B. (1006 aa)
ILKIntegrin linked kinase. (483 aa)
PAK6Non-specific serine/threonine protein kinase. (706 aa)
NFATC4Nuclear factor of activated T cells 4. (963 aa)
NFATC3Nuclear factor of activated T cells 3. (1088 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1086 aa)
SEMA5BSemaphorin 5B. (1157 aa)
RHOCUncharacterized protein. (100 aa)
EFNB3Ephrin B3; Belongs to the ephrin family. (340 aa)
PTCH1Patched 1. (1440 aa)
GNAI2G protein subunit alpha i2. (355 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1288 aa)
MAPK1Mitogen-activated protein kinase 1. (305 aa)
NTN4Netrin 4. (625 aa)
EPHA6EPH receptor A6. (1018 aa)
SRGAP3SLIT-ROBO Rho GTPase activating protein 3. (1099 aa)
ROBO1Roundabout guidance receptor 1. (1651 aa)
ROBO2Roundabout guidance receptor 2. (1439 aa)
EFNA4Ephrin A4; Belongs to the ephrin family. (201 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (829 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (887 aa)
NEO1Neogenin 1. (1463 aa)
BMP7Bone morphogenetic protein 7. (430 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
SRCTyrosine-protein kinase. (542 aa)
RHODRas homolog family member D. (195 aa)
SRGAP1SLIT-ROBO Rho GTPase activating protein 1. (1085 aa)
GNAI1G protein subunit alpha i1. (311 aa)
SRGAP2Uncharacterized protein. (1071 aa)
PPP3CBSerine/threonine-protein phosphatase. (496 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (821 aa)
NTNG2Netrin G2. (512 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (770 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
PAK4Non-specific serine/threonine protein kinase. (594 aa)
MAPK3Mitogen-activated protein kinase. (322 aa)
NGEFNeuronal guanine nucleotide exchange factor. (707 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (777 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (336 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
EFNA3Ephrin RBD domain-containing protein; Belongs to the ephrin family. (232 aa)
RGS3Regulator of G protein signaling 3. (1091 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (772 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
ABLIM3Actin binding LIM protein family member 3. (702 aa)
FYNTyrosine-protein kinase. (537 aa)
EPHA7EPH receptor A7. (998 aa)
EPHA4EPH receptor A4. (949 aa)
PARD3Par-3 family cell polarity regulator. (1316 aa)
PARD6APar-6 family cell polarity regulator alpha. (385 aa)
ENSSBOP00000032178Uncharacterized protein. (185 aa)
DCCDCC netrin 1 receptor. (1447 aa)
SEMA5ASemaphorin 5A. (1074 aa)
PARD6BPar-6 family cell polarity regulator beta. (361 aa)
EPHB6EPH receptor B6. (1022 aa)
EPHB4EPH receptor B4. (987 aa)
PLXNA2Plexin A2. (1909 aa)
L1CAML1 cell adhesion molecule. (1263 aa)
EPHB3EPH receptor B3. (989 aa)
NCK1Cytoplasmic protein. (377 aa)
PAK2Non-specific serine/threonine protein kinase. (525 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (400 aa)
PPP3CASerine/threonine-protein phosphatase. (505 aa)
PIK3R2Uncharacterized protein. (674 aa)
PLXNC1Plexin C1. (1499 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
SSH3Slingshot protein phosphatase 3. (652 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (775 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
PLXNA3Plexin A3. (1896 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (667 aa)
PAK1Non-specific serine/threonine protein kinase. (555 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (727 aa)
MYL9Myosin light chain 9. (172 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (921 aa)
SSH1Slingshot protein phosphatase 1. (1006 aa)
Your Current Organism:
Saimiri boliviensis
NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis
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