52 items (Saimiri boliviensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PLA2G4B	Phospholipase A2. (781 aa)
	SPHK1	Sphingosine kinase 1. (488 aa)
	RAC3	Rac family small GTPase 3. (311 aa)
	CASP9	Caspase 9; Belongs to the peptidase C14A family. (401 aa)
	RAF1	Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (520 aa)
	NOS3	Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (486 aa)
	PIK3CB	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1091 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	MAPK12	Mitogen-activated protein kinase. (367 aa)
	RAC2	Rac family small GTPase 2. (192 aa)
	PPP3R1	Uncharacterized protein. (189 aa)
	PTK2	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (979 aa)
	PRKCG	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa)
	KRAS	KRAS proto-oncogene, GTPase. (189 aa)
	MAP2K1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
	HRAS	HRas proto-oncogene, GTPase. (189 aa)
	NFATC2	Nuclear factor of activated T cells 2. (937 aa)
	RAC1	Uncharacterized protein. (207 aa)
	PIK3R3	Uncharacterized protein. (461 aa)
	KDR	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
	CDC42	Uncharacterized protein. (191 aa)
	BAD	BCL2 associated agonist of cell death. (167 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	PLA2G4E	Phospholipase A2. (862 aa)
	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1288 aa)
	MAPK1	Mitogen-activated protein kinase 1. (305 aa)
	PRKCB	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
	MAPKAPK2	MAPK activated protein kinase 2. (396 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	SRC	Tyrosine-protein kinase. (542 aa)
	PLA2G4D	Phospholipase A2. (817 aa)
	PTGS2	Prostaglandin-endoperoxide synthase 2. (604 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (496 aa)
	PLA2G4A	Phospholipase A2. (655 aa)
	MAPK3	Mitogen-activated protein kinase. (322 aa)
	VEGFA	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (193 aa)
	SPHK2	Sphingosine kinase 2. (656 aa)
	MAPKAPK3	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (382 aa)
	MAP2K2	Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (369 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (505 aa)
	PIK3R2	Uncharacterized protein. (674 aa)
	MAPK13	Mitogen-activated protein kinase. (450 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
	MAPK11	Mitogen-activated protein kinase. (372 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (727 aa)
	PLA2G4F	Phospholipase A2. (849 aa)
	SH2D2A	SH2 domain containing 2A. (389 aa)

Your Current Organism:

Saimiri boliviensis

NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSSBOP00000006552	ENSSBOP00000038751	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.971
AKT1	AKT3	ENSSBOP00000006552	ENSSBOP00000026533	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.937
AKT1	BAD	ENSSBOP00000006552	ENSSBOP00000018634	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	BCL2 associated agonist of cell death.	0.982
AKT1	CASP9	ENSSBOP00000006552	ENSSBOP00000001771	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Caspase 9; Belongs to the peptidase C14A family.	0.975
AKT1	CDC42	ENSSBOP00000006552	ENSSBOP00000018173	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.540
AKT1	HRAS	ENSSBOP00000006552	ENSSBOP00000012967	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	HRas proto-oncogene, GTPase.	0.614
AKT1	KRAS	ENSSBOP00000006552	ENSSBOP00000011323	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	KRAS proto-oncogene, GTPase.	0.513
AKT1	MAP2K2	ENSSBOP00000006552	ENSSBOP00000035042	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.	0.426
AKT1	MAPK1	ENSSBOP00000006552	ENSSBOP00000023855	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase 1.	0.958
AKT1	MAPK11	ENSSBOP00000006552	ENSSBOP00000037671	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.936
AKT1	MAPK12	ENSSBOP00000006552	ENSSBOP00000008484	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.931
AKT1	MAPK13	ENSSBOP00000006552	ENSSBOP00000037013	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.933
AKT1	MAPK14	ENSSBOP00000006552	ENSSBOP00000022944	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.964
AKT1	MAPK3	ENSSBOP00000006552	ENSSBOP00000028392	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.947
AKT1	MAPKAPK2	ENSSBOP00000006552	ENSSBOP00000025247	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	MAPK activated protein kinase 2.	0.666
AKT1	NOS3	ENSSBOP00000006552	ENSSBOP00000005123	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Nitric oxide synthase; Produces nitric oxide (NO).	0.980
AKT1	NRAS	ENSSBOP00000006552	ENSSBOP00000008278	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	NRAS proto-oncogene, GTPase.	0.507
AKT1	PIK3CA	ENSSBOP00000006552	ENSSBOP00000006220	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.980
AKT1	PIK3CB	ENSSBOP00000006552	ENSSBOP00000007916	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.979
AKT1	PIK3R1	ENSSBOP00000006552	ENSSBOP00000039285	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphoinositide-3-kinase regulatory subunit 1.	0.972