STRINGSTRING
RAC3 RAC3 CSNK2A1 CSNK2A1 FER FER PTPRJ PTPRJ NLK NLK MET MET PTPRF PTPRF TGFBR1 TGFBR1 NECTIN3 NECTIN3 TJP1 TJP1 SMAD3 SMAD3 PTPN1 PTPN1 RAC2 RAC2 AFDN AFDN CTNNA1 CTNNA1 IGF1R IGF1R CDH1 CDH1 WASF2 WASF2 INSR INSR PTPN6 PTPN6 IQGAP1 IQGAP1 TCF7 TCF7 CTNNA2 CTNNA2 RAC1 RAC1 TCF7L1 TCF7L1 WASF3 WASF3 CDC42 CDC42 CTNND1 CTNND1 WASF1 WASF1 CSNK2A2 CSNK2A2 NECTIN1 NECTIN1 EP300 EP300 CREBBP CREBBP EGFR EGFR RHOC RHOC MAPK1 MAPK1 ACTN1 ACTN1 CTNNA3 CTNNA3 ERBB2 ERBB2 CTNNB1 CTNNB1 SMAD4 SMAD4 SRC SRC ACTN4 ACTN4 MAPK3 MAPK3 FYN FYN BAIAP2 BAIAP2 PARD3 PARD3 WAS WAS MAP3K7 MAP3K7 TGFBR2 TGFBR2 ACTB ACTB PTPRB PTPRB SNAI1 SNAI1 YES1 YES1 WASL WASL SNAI2 SNAI2 PTPRM PTPRM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAC3Rac family small GTPase 3. (311 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (385 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1293 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (519 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1406 aa)
PTPRFProtein tyrosine phosphatase receptor type F. (1899 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
NECTIN3Nectin cell adhesion molecule 3. (503 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1770 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
RAC2Rac family small GTPase 2. (192 aa)
AFDNAfadin, adherens junction formation factor. (1820 aa)
CTNNA1Catenin alpha 1. (906 aa)
IGF1RTyrosine-protein kinase receptor. (1366 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (819 aa)
WASF2WASP family member 2. (498 aa)
INSRTyrosine-protein kinase receptor. (1388 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1673 aa)
TCF7Transcription factor 7. (399 aa)
CTNNA2Catenin alpha 2. (953 aa)
RAC1Uncharacterized protein. (207 aa)
TCF7L1Transcription factor 7 like 1. (483 aa)
WASF3WASP family member 3. (502 aa)
CDC42Uncharacterized protein. (191 aa)
CTNND1Catenin delta 1. (967 aa)
WASF1WASP family member 1. (559 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (337 aa)
NECTIN1Nectin cell adhesion molecule 1. (516 aa)
EP300E1A binding protein p300. (2420 aa)
CREBBPCREB binding protein. (2439 aa)
EGFRReceptor protein-tyrosine kinase. (1196 aa)
RHOCUncharacterized protein. (100 aa)
MAPK1Mitogen-activated protein kinase 1. (305 aa)
ACTN1Actinin alpha 1. (914 aa)
CTNNA3Catenin alpha 3. (895 aa)
ERBB2Receptor protein-tyrosine kinase. (1254 aa)
CTNNB1Catenin beta 1. (781 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
SRCTyrosine-protein kinase. (542 aa)
ACTN4Actinin alpha 4. (930 aa)
MAPK3Mitogen-activated protein kinase. (322 aa)
FYNTyrosine-protein kinase. (537 aa)
BAIAP2BAI1 associated protein 2. (531 aa)
PARD3Par-3 family cell polarity regulator. (1316 aa)
WASWASP actin nucleation promoting factor. (502 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
ACTBActin beta. (378 aa)
PTPRBProtein tyrosine phosphatase receptor type B. (2217 aa)
SNAI1Snail family transcriptional repressor 1. (265 aa)
YES1Tyrosine-protein kinase. (548 aa)
WASLWASP like actin nucleation promoting factor. (507 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
PTPRMProtein tyrosine phosphatase receptor type M. (1440 aa)
Your Current Organism:
Saimiri boliviensis
NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis
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