STRINGSTRING
GCK GCK KCNN1 KCNN1 ENSSBOP00000002529 ENSSBOP00000002529 CACNA1S CACNA1S KCNJ11 KCNJ11 GNA11 GNA11 KCNN4 KCNN4 SLC2A2 SLC2A2 CREB3L2 CREB3L2 CREB5 CREB5 KCNN3 KCNN3 ATP1A1 ATP1A1 GIP GIP ATF4 ATF4 ABCC8 ABCC8 SLC2A1 SLC2A1 GNAQ GNAQ PRKCG PRKCG ATF6B ATF6B ADCY3 ADCY3 ITPR3 ITPR3 CREB3L3 CREB3L3 RAB3A RAB3A KCNMB2 KCNMB2 ADCY8 ADCY8 ATP1B2 ATP1B2 PLCB1 PLCB1 CACNA1F CACNA1F RYR2 RYR2 ATP1B3 ATP1B3 VAMP2 VAMP2 CAMK2A CAMK2A ATF2 ATF2 ADCY2 ADCY2 TRPM4 TRPM4 GLP1R GLP1R ADCY5 ADCY5 KCNMB1 KCNMB1 CREB3L1 CREB3L1 KCNN2 KCNN2 ATP1A3 ATP1A3 CACNA1C CACNA1C ADCY6 ADCY6 ADCYAP1 ADCYAP1 PRKACA PRKACA PRKCB PRKCB KCNU1 KCNU1 CCKAR CCKAR PLCB4 PLCB4 CACNA1D CACNA1D ADCY7 ADCY7 CREB3 CREB3 RAPGEF4 RAPGEF4 PDX1 PDX1 PLCB2 PLCB2 GNAS GNAS INS INS GCG GCG PRKACB PRKACB ADCY1 ADCY1 ATP1B1 ATP1B1 FXYD2 FXYD2 CCK CCK KCNMB4 KCNMB4 ATP1B4 ATP1B4 CREB1 CREB1 PRKCA PRKCA PLCB3 PLCB3 STX1A STX1A ADCY4 ADCY4 CREB3L4 CREB3L4 PCLO PCLO SNAP25 SNAP25 ADCY9 ADCY9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GCKPhosphotransferase. (466 aa)
KCNN1Potassium calcium-activated channel subfamily N member 1. (543 aa)
ENSSBOP00000002529Uncharacterized protein. (247 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1880 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
GNA11G protein subunit alpha 11. (358 aa)
KCNN4Potassium calcium-activated channel subfamily N member 4. (427 aa)
SLC2A2Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (524 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
KCNN3Potassium calcium-activated channel subfamily N member 3. (739 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
GIPGastric inhibitory polypeptide. (124 aa)
ATF4Activating transcription factor 4. (351 aa)
ABCC8ATP binding cassette subfamily C member 8. (1582 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (498 aa)
GNAQG protein subunit alpha q. (301 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa)
ATF6BActivating transcription factor 6 beta. (689 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1144 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2673 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (467 aa)
RAB3ARAB3A, member RAS oncogene family. (220 aa)
KCNMB2KcnmB2_inactiv domain-containing protein. (235 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1209 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1981 aa)
RYR2Ryanodine receptor 2. (4909 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (274 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (118 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (507 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1216 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (428 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1018 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (518 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (1033 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2169 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1257 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (173 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
KCNU1Potassium calcium-activated channel subfamily U member 1. (1149 aa)
CCKARCholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family. (432 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2182 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1079 aa)
CREB3cAMP responsive element binding protein 3. (371 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (1001 aa)
PDX1Pancreatic and duodenal homeobox 1. (282 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
GNASGNAS complex locus. (897 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (108 aa)
GCGGlucagon. (180 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
FXYD2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
CCKCholecystokinin. (115 aa)
KCNMB4Potassium calcium-activated channel subfamily M regulatory beta subunit 4. (210 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (353 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1229 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (288 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1128 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (413 aa)
PCLOUncharacterized protein. (1217 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
Your Current Organism:
Saimiri boliviensis
NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis
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