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ND1 ND1 ND2 ND2 COX1 COX1 COX2 COX2 ATP8 ATP8 ATP6 ATP6 COX3 COX3 ND3 ND3 ND4L ND4L ND4 ND4 ND5 ND5 ND6 ND6 CYTB CYTB SDHC SDHC NDUFA4L2 NDUFA4L2 POLR2A POLR2A DCTN5 DCTN5 HTT HTT SLC25A31 SLC25A31 ATP5F1A ATP5F1A ENSSBOP00000001155 ENSSBOP00000001155 PPARGC1A PPARGC1A ENSSBOP00000001323 ENSSBOP00000001323 PSMC3 PSMC3 PPARG PPARG CASP9 CASP9 ENSSBOP00000001979 ENSSBOP00000001979 DNAH2 DNAH2 AP2M1 AP2M1 ATP5G2 ATP5G2 ENSSBOP00000002452 ENSSBOP00000002452 PPIF PPIF NDUFS4 NDUFS4 DCTN3 DCTN3 SHFM1 SHFM1 POLR2G POLR2G TAF4 TAF4 ATP5PB ATP5PB DNALI1 DNALI1 WIPI2 WIPI2 POLR2D POLR2D NDUFA13 NDUFA13 TUBB4A TUBB4A NDUFV3 NDUFV3 CREB3L2 CREB3L2 NDUFA4 NDUFA4 MAPK9 MAPK9 TBPL2 TBPL2 ACTR1A ACTR1A CREB5 CREB5 PSMA2 PSMA2 NDUFA8 NDUFA8 NDUFA3 NDUFA3 ENSSBOP00000006366 ENSSBOP00000006366 CACNA1B CACNA1B NDUFAB1 NDUFAB1 COX7A1 COX7A1 DNAH1 DNAH1 PSMC2 PSMC2 NDUFS8 NDUFS8 ENSSBOP00000008160 ENSSBOP00000008160 TUBB TUBB ENSSBOP00000008273 ENSSBOP00000008273 TUBA8 TUBA8 GPX3 GPX3 ACTR10 ACTR10 NDUFA6 NDUFA6 GPX5 GPX5 GNAQ GNAQ ENSSBOP00000009158 ENSSBOP00000009158 BECN1 BECN1 PSMA3 PSMA3 NDUFA2 NDUFA2 VDAC2 VDAC2 NDUFB4 NDUFB4 NDUFA5 NDUFA5 DNAH5 DNAH5 AMBRA1 AMBRA1 GRIA2 GRIA2 IFT57 IFT57 SP1 SP1 ENSSBOP00000010642 ENSSBOP00000010642 PSMC6 PSMC6 TUBA1B TUBA1B CREB3L3 CREB3L3 CASP3 CASP3 TUBB6 TUBB6 AP2A1 AP2A1 SLC1A3 SLC1A3 ATP5MC3 ATP5MC3 NRF1 NRF1 TBPL1 TBPL1 DNAH12 DNAH12 PSMB3 PSMB3 ITPR1 ITPR1 NDUFC2 NDUFC2 COX5B COX5B PSMA8 PSMA8 SDHB SDHB POLR2F POLR2F TUBB2A TUBB2A NDUFB11 NDUFB11 COX7C COX7C PSMC1 PSMC1 PSMD14 PSMD14 NDUFA9 NDUFA9 DNAH7 DNAH7 TAF4B TAF4B DNAI1 DNAI1 NDUFB3 NDUFB3 PSMD2 PSMD2 COX7B COX7B KLC4 KLC4 ATP5F1C ATP5F1C RB1CC1 RB1CC1 COX8A COX8A PSMD1 PSMD1 NDUFS2 NDUFS2 PLCB1 PLCB1 SDHA SDHA PSMA4 PSMA4 ATG101 ATG101 PSMB6 PSMB6 ENSSBOP00000016113 ENSSBOP00000016113 PSMB4 PSMB4 TFAM TFAM ENSSBOP00000016197 ENSSBOP00000016197 TUBB4B TUBB4B ENSSBOP00000017323 ENSSBOP00000017323 GRIA4 GRIA4 GRIA3 GRIA3 POLR2J POLR2J HDAC1 HDAC1 VDAC1 VDAC1 DNAH11 DNAH11 DNAL1 DNAL1 HDAC2 HDAC2 ATG2A ATG2A ADRM1 ADRM1 UCP1 UCP1 KLC2 KLC2 CREB3L1 CREB3L1 CYC1 CYC1 GPX1 GPX1 PSMD3 PSMD3 DNAH9 DNAH9 ACTR1B ACTR1B DNAH14 DNAH14 DNAH6 DNAH6 POLR2E POLR2E SIN3A SIN3A EP300 EP300 CASP8 CASP8 GPX6 GPX6 NDUFB7 NDUFB7 COX6A1 COX6A1 KIF5A KIF5A SDHD SDHD CREBBP CREBBP BDNF BDNF SLC25A4 SLC25A4 GPX2 GPX2 ATG2B ATG2B TUBB3 TUBB3 PSMD11 PSMD11 DNAH3 DNAH3 DCTN6 DCTN6 PSMB7 PSMB7 DNAH17 DNAH17 ENSSBOP00000023602 ENSSBOP00000023602 TRAF2 TRAF2 ENSSBOP00000023806 ENSSBOP00000023806 NRBF2 NRBF2 COX6A2 COX6A2 TUBAL3 TUBAL3 NDUFS1 NDUFS1 ENSSBOP00000024485 ENSSBOP00000024485 ATP5G1 ATP5G1 PIK3C3 PIK3C3 TGM2 TGM2 KLC1 KLC1 PSMB1 PSMB1 ENSSBOP00000025572 ENSSBOP00000025572 KCNJ10 KCNJ10 MAPK10 MAPK10 CLTB CLTB ENSSBOP00000025905 ENSSBOP00000025905 PLCB4 PLCB4 UQCRC1 UQCRC1 GRM5 GRM5 NDUFS6 NDUFS6 ATP5O ATP5O NDUFB5 NDUFB5 TUBA4A TUBA4A POLR2C POLR2C PSMA7 PSMA7 PSMA5 PSMA5 ATG14 ATG14 CREB3 CREB3 PSMB5 PSMB5 NDUFV1 NDUFV1 COX4I1 COX4I1 POLR2I POLR2I UQCRQ UQCRQ CLTCL1 CLTCL1 PSMA6 PSMA6 NDUFB10 NDUFB10 SLC1A2 SLC1A2 TUBB1 TUBB1 NDUFB2 NDUFB2 ATP5PF ATP5PF PLCB2 PLCB2 NDUFS5 NDUFS5 PSMD7 PSMD7 ULK2 ULK2 MAP3K5 MAP3K5 UQCRFS1 UQCRFS1 NDUFA11 NDUFA11 APAF1 APAF1 TBP TBP REST REST DCTN4 DCTN4 ENSSBOP00000032312 ENSSBOP00000032312 ATP5F1E ATP5F1E AP2S1 AP2S1 NDUFB8 NDUFB8 SLC25A6 SLC25A6 POLR2H POLR2H KLC3 KLC3 DNAH10 DNAH10 GPX8 GPX8 PIK3R4 PIK3R4 ENSSBOP00000035257 ENSSBOP00000035257 SOD2 SOD2 DNAH8 DNAH8 CREB1 CREB1 PSMA1 PSMA1 AP2B1 AP2B1 PSMC4 PSMC4 DNAI2 DNAI2 PSMC5 PSMC5 VDAC3 VDAC3 UQCRB UQCRB MTOR MTOR DCTN2 DCTN2 NDUFA10 NDUFA10 MAPK8 MAPK8 PSMD9 PSMD9 CLTC CLTC GRIN1 GRIN1 GRIN2B GRIN2B PLCB3 PLCB3 STX1A STX1A PSMB2 PSMB2 COX7A2L COX7A2L GRIA1 GRIA1 NDUFB9 NDUFB9 CREB3L4 CREB3L4 ERN1 ERN1 ATP5F1B ATP5F1B NDUFV2 NDUFV2 SOD1 SOD1 PSMD8 PSMD8 KIF5B KIF5B DLG4 DLG4 AP2A2 AP2A2 WIPI1 WIPI1 DCTN1 DCTN1 NDUFA12 NDUFA12 DNAL4 DNAL4 ENSSBOP00000040325 ENSSBOP00000040325
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
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ND1NADH-ubiquinone oxidoreductase chain 1; Belongs to the complex I subunit 1 family. (318 aa)
ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (346 aa)
COX1Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (513 aa)
COX2Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (224 aa)
ATP8ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (66 aa)
ATP6ATP synthase subunit a. (226 aa)
COX3Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (261 aa)
ND3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (115 aa)
ND4LNADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (98 aa)
ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (458 aa)
ND5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (602 aa)
ND6NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (177 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa)
SDHCUncharacterized protein. (169 aa)
NDUFA4L2NDUFA4 mitochondrial complex associated like 2. (87 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa)
DCTN5Dynactin subunit 5. (182 aa)
HTTHuntingtin. (3059 aa)
SLC25A31Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (316 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (574 aa)
ENSSBOP00000001155Uncharacterized protein. (153 aa)
PPARGC1APPARG coactivator 1 alpha. (802 aa)
ENSSBOP00000001323Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (482 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (401 aa)
ENSSBOP00000001979Uncharacterized protein. (63 aa)
DNAH2Dynein axonemal heavy chain 2. (4426 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (435 aa)
ATP5G2ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (198 aa)
ENSSBOP00000002452Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (207 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (175 aa)
DCTN3Dynactin subunit 3. (186 aa)
SHFM1Uncharacterized protein. (70 aa)
POLR2GRNA polymerase II subunit G. (185 aa)
TAF4TATA-box binding protein associated factor 4. (634 aa)
ATP5PBATP synthase peripheral stalk-membrane subunit b. (256 aa)
DNALI1Dynein axonemal light intermediate chain 1. (281 aa)
WIPI2Uncharacterized protein. (430 aa)
POLR2DRPOL4c domain-containing protein. (110 aa)
NDUFA13NADH:ubiquinone oxidoreductase subunit A13. (144 aa)
TUBB4ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (372 aa)
NDUFV3NADH:ubiquinone oxidoreductase subunit V3. (474 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
NDUFA4Uncharacterized protein. (82 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
TBPL2TATA-box binding protein like 2. (364 aa)
ACTR1AActin related protein 1A. (376 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
NDUFA8NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (172 aa)
NDUFA3Uncharacterized protein. (84 aa)
ENSSBOP00000006366Uncharacterized protein. (429 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2320 aa)
NDUFAB1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (156 aa)
COX7A1Cytochrome c oxidase subunit 7A1. (80 aa)
DNAH1Dynein axonemal heavy chain 1. (4265 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (472 aa)
NDUFS8NADH:ubiquinone oxidoreductase core subunit S8. (211 aa)
ENSSBOP00000008160Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (302 aa)
TUBBTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
ENSSBOP00000008273Uncharacterized protein. (95 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (383 aa)
GPX3Uncharacterized protein. (72 aa)
ACTR10Actin related protein 10; Belongs to the actin family. (400 aa)
NDUFA6NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (128 aa)
GPX5Glutathione peroxidase; Belongs to the glutathione peroxidase family. (220 aa)
GNAQG protein subunit alpha q. (301 aa)
ENSSBOP00000009158Uncharacterized protein. (72 aa)
BECN1Uncharacterized protein. (450 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
NDUFA2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (99 aa)
VDAC2Uncharacterized protein. (294 aa)
NDUFB4NADH:ubiquinone oxidoreductase subunit B4. (128 aa)
NDUFA5Uncharacterized protein. (116 aa)
DNAH5Dynein axonemal heavy chain 5. (4624 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1299 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
IFT57Intraflagellar transport 57. (429 aa)
SP1Sp1 transcription factor. (726 aa)
ENSSBOP00000010642Uncharacterized protein. (131 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (364 aa)
TUBA1BTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (456 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (467 aa)
CASP3Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Belongs to the peptidase C14A family. (277 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (374 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (967 aa)
SLC1A3Amino acid transporter. (542 aa)
ATP5MC3ATP synthase membrane subunit c locus 3; Belongs to the ATPase C chain family. (141 aa)
NRF1Nuclear respiratory factor 1. (522 aa)
TBPL1TATA-box binding protein like 1. (186 aa)
DNAH12Uncharacterized protein. (3922 aa)
PSMB3Proteasome subunit beta. (208 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2747 aa)
NDUFC2NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (121 aa)
COX5BCytochrome c oxidase subunit 5B. (126 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (267 aa)
POLR2FRNA polymerase II subunit F. (147 aa)
TUBB2ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
NDUFB11Uncharacterized protein. (153 aa)
COX7CCytochrome c oxidase subunit 7C. (63 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (448 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
NDUFA9NADH:ubiquinone oxidoreductase subunit A9. (377 aa)
DNAH7Dynein axonemal heavy chain 7. (4024 aa)
TAF4BTATA-box binding protein associated factor 4b. (861 aa)
DNAI1Dynein axonemal intermediate chain 1. (802 aa)
NDUFB3NADH:ubiquinone oxidoreductase subunit B3. (98 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (808 aa)
COX7BCytochrome c oxidase subunit 7B. (82 aa)
KLC4Kinesin light chain 4. (618 aa)
ATP5F1CATP synthase subunit gamma. (298 aa)
RB1CC1RB1 inducible coiled-coil 1. (1548 aa)
COX8ACytochrome c oxidase subunit 8A. (69 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (949 aa)
NDUFS2NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (462 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (701 aa)
PSMA4Proteasome subunit alpha type. (284 aa)
ATG101Autophagy related 101. (218 aa)
PSMB6Proteasome subunit beta. (240 aa)
ENSSBOP00000016113Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (148 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
TFAMTranscription factor A, mitochondrial. (247 aa)
ENSSBOP00000016197Uncharacterized protein. (96 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (429 aa)
ENSSBOP00000017323Uncharacterized protein. (288 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (902 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (895 aa)
POLR2JRNA polymerase II subunit J. (117 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
VDAC1Voltage dependent anion channel 1. (283 aa)
DNAH11Dynein axonemal heavy chain 11. (4395 aa)
DNAL1Uncharacterized protein. (122 aa)
HDAC2Hist_deacetyl domain-containing protein. (314 aa)
ATG2AAutophagy related 2A. (1933 aa)
ADRM1Adhesion regulating molecule 1. (407 aa)
UCP1Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
KLC2Kinesin light chain 2. (729 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
CYC1Cytochrome c1. (266 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (145 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
DNAH9Dynein axonemal heavy chain 9. (4460 aa)
ACTR1BActin related protein 1B. (376 aa)
DNAH14Uncharacterized protein. (4500 aa)
DNAH6Dynein axonemal heavy chain 6. (4068 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
EP300E1A binding protein p300. (2420 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (494 aa)
GPX6Glutathione peroxidase; Belongs to the glutathione peroxidase family. (218 aa)
NDUFB7NADH:ubiquinone oxidoreductase subunit B7. (138 aa)
COX6A1Cytochrome c oxidase subunit 6A, mitochondrial. (108 aa)
KIF5AKinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1032 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa)
CREBBPCREB binding protein. (2439 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (330 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (296 aa)
GPX2Glutathione peroxidase; Belongs to the glutathione peroxidase family. (150 aa)
ATG2BAutophagy related 2B. (2079 aa)
TUBB3Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (440 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
DNAH3Dynein axonemal heavy chain 3. (4101 aa)
DCTN6Dynactin subunit 6. (190 aa)
PSMB7Proteasome subunit beta. (277 aa)
DNAH17Dynein axonemal heavy chain 17. (4386 aa)
ENSSBOP00000023602Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (467 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (526 aa)
ENSSBOP00000023806Uncharacterized protein. (96 aa)
NRBF2Uncharacterized protein. (273 aa)
COX6A2Cytochrome c oxidase subunit 6A, mitochondrial. (95 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
NDUFS1NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (728 aa)
ENSSBOP00000024485Uncharacterized protein. (69 aa)
ATP5G1ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (136 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
TGM2Transglutaminase 2. (687 aa)
KLC1Kinesin light chain 1. (704 aa)
PSMB1Proteasome subunit beta. (241 aa)
ENSSBOP00000025572Uncharacterized protein. (85 aa)
KCNJ10IRK domain-containing protein. (207 aa)
MAPK10Mitogen-activated protein kinase. (541 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (181 aa)
ENSSBOP00000025905Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (102 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
UQCRC1Ubiquinol-cytochrome c reductase core protein 1. (480 aa)
GRM5Glutamate metabotropic receptor 5. (1211 aa)
NDUFS6NADH:ubiquinone oxidoreductase subunit S6. (172 aa)
ATP5OUncharacterized protein. (213 aa)
NDUFB5Uncharacterized protein. (80 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
PSMA7Proteasome endopeptidase complex. (251 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
ATG14Autophagy related 14. (492 aa)
CREB3cAMP responsive element binding protein 3. (371 aa)
PSMB5Proteasome subunit beta. (283 aa)
NDUFV1Uncharacterized protein. (121 aa)
COX4I1Cytochrome c oxidase subunit 4I1. (169 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
UQCRQUbiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1642 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
NDUFB10NADH:ubiquinone oxidoreductase subunit B10. (173 aa)
SLC1A2Amino acid transporter. (577 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
NDUFB2Uncharacterized protein. (105 aa)
ATP5PFATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (119 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
NDUFS5Uncharacterized protein. (106 aa)
PSMD7MPN domain-containing protein. (324 aa)
ULK2Unc-51 like autophagy activating kinase 2. (925 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1354 aa)
UQCRFS1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (225 aa)
NDUFA11Uncharacterized protein. (141 aa)
APAF1Apoptotic peptidase activating factor 1. (1193 aa)
TBPTATA-box binding protein. (326 aa)
RESTRE1 silencing transcription factor. (1110 aa)
DCTN4Dynactin subunit 4. (467 aa)
ENSSBOP00000032312Uncharacterized protein. (56 aa)
ATP5F1EATP synthase F1 subunit epsilon. (55 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (157 aa)
NDUFB8NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa)
SLC25A6Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (156 aa)
POLR2HRNA polymerase II subunit H. (196 aa)
KLC3Kinesin light chain 3. (436 aa)
DNAH10Dynein axonemal heavy chain 10. (4394 aa)
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa)
ENSSBOP00000035257Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (91 aa)
SOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (155 aa)
DNAH8Dynein axonemal heavy chain 8. (4558 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
PSMA1Proteasome endopeptidase complex. (189 aa)
AP2B1AP complex subunit beta. (951 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
DNAI2Dynein axonemal intermediate chain 2. (605 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (416 aa)
VDAC3Voltage dependent anion channel 3. (314 aa)
UQCRBUbiquinol-cytochrome c reductase binding protein. (161 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
DCTN2Dynactin subunit 2. (406 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (316 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
PSMD9PDZ domain-containing protein. (223 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1682 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (864 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1483 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1229 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (288 aa)
PSMB2Proteasome subunit beta. (201 aa)
COX7A2LCytochrome c oxidase subunit 7A2 like. (113 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (915 aa)
NDUFB9NADH:ubiquinone oxidoreductase subunit B9; Belongs to the complex I LYR family. (185 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (413 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (964 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (467 aa)
NDUFV2NADH:ubiquinone oxidoreductase core subunit V2. (301 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (763 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (969 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (417 aa)
DCTN1CAP-Gly domain-containing protein. (1278 aa)
NDUFA12NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (145 aa)
DNAL4Dynein light chain. (105 aa)
ENSSBOP00000040325ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (159 aa)
Your Current Organism:
Saimiri boliviensis
NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis
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