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Ccel_1212 Ccel_1212 Ccel_1332 Ccel_1332 Ccel_1469 Ccel_1469 Ccel_1607 Ccel_1607 Ccel_1624 Ccel_1624 Ccel_1684 Ccel_1684 Ccel_1778 Ccel_1778 Ccel_1860 Ccel_1860 Ccel_1058 Ccel_1058 leuA leuA Ccel_1057 Ccel_1057 Ccel_0951 Ccel_0951 Ccel_0949 Ccel_0949 Ccel_0943 Ccel_0943 Ccel_0942 Ccel_0942 Ccel_0868 Ccel_0868 Ccel_0867 Ccel_0867 Ccel_0866 Ccel_0866 Ccel_0686 Ccel_0686 Ccel_0632 Ccel_0632 Ccel_0494 Ccel_0494 Ccel_0419 Ccel_0419 Ccel_3433 Ccel_3433 Ccel_3189 Ccel_3189 argB argB argC argC Ccel_2434 Ccel_2434 Ccel_1870 Ccel_1870 iscS iscS Ccel_2177 Ccel_2177
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Ccel_1212PFAM: aminoglycoside phosphotransferase; KEGG: cac:CAC2572 aminoglycoside phosphotransferase. (268 aa)
Ccel_1332TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: cno:NT01CX_0374 bifunctional folate synthesis protein. (157 aa)
Ccel_1469PFAM: AMP-dependent synthetase and ligase; KEGG: cth:Cthe_0551 AMP-dependent synthetase and ligase. (559 aa)
Ccel_1607Electron transfer flavoprotein alpha subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Electron transfer flavoprotein alpha/beta-subunit; Electron transfer flavoprotein alpha subunit; KEGG: cno:NT01CX_1204 electron transfer flavoprotein, alpha subunit. (399 aa)
Ccel_1624PFAM: pyruvate carboxyltransferase; KEGG: mth:MTH1630 trans-homoaconitate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (388 aa)
Ccel_1684PFAM: aminotransferase class V; KEGG: cth:Cthe_1064 aminotransferase, class V. (387 aa)
Ccel_1778PFAM: amine oxidase; KEGG: cpy:Cphy_2915 amine oxidase. (572 aa)
Ccel_1860PFAM: Rhomboid family protein; KEGG: cth:Cthe_1048 rhomboid family protein. (519 aa)
Ccel_1058PFAM: HI0933 family protein; FAD dependent oxidoreductase; KEGG: cbk:CLL_A1369 pyridine nucleotide-disulphide oxidoreductase domain protein. (425 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (508 aa)
Ccel_1057KEGG: cbk:CLL_A1370 pyridine nucleotide-disulphide oxidoreductase domain protein. (426 aa)
Ccel_0951KEGG: bcl:ABC3582 hypothetical protein. (432 aa)
Ccel_0949PFAM: FAD dependent oxidoreductase; KEGG: rle:RL3853 putative protein involved in invasion. (457 aa)
Ccel_0943PFAM: FAD dependent oxidoreductase; KEGG: rle:RL3853 putative protein involved in invasion. (457 aa)
Ccel_0942KEGG: cpy:Cphy_3243 hypothetical protein. (457 aa)
Ccel_0868PFAM: Beta-ketoacyl synthase; KEGG: bcl:ABC2546 3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (431 aa)
Ccel_0867PFAM: Beta-ketoacyl synthase; KEGG: tye:THEYE_A0103 beta-ketoacyl-acyl carrier protein synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (423 aa)
Ccel_0866PFAM: Beta-ketoacyl synthase; KEGG: tte:TTE1470 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (410 aa)
Ccel_06863-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (411 aa)
Ccel_0632KEGG: cts:Ctha_2703 hypothetical protein. (115 aa)
Ccel_0494PFAM: AMP-dependent synthetase and ligase; KEGG: cth:Cthe_0551 AMP-dependent synthetase and ligase. (552 aa)
Ccel_0419PFAM: metal-dependent protein hydrolase; KEGG: amt:Amet_0463 metal-dependent protein hydrolase. (331 aa)
Ccel_3433TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: cth:Cthe_2519 alpha-isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (520 aa)
Ccel_3189PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: cpy:Cphy_2083 biotin synthase. (345 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (303 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (313 aa)
Ccel_2434TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: amt:Amet_2650 putative agmatinase; Belongs to the arginase family. (287 aa)
Ccel_1870PFAM: thioesterase superfamily protein; KEGG: cpy:Cphy_2327 thioesterase superfamily protein. (159 aa)
iscSCysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (393 aa)
Ccel_2177PFAM: pyruvate carboxyltransferase; KEGG: cth:Cthe_3157 pyruvate carboxyltransferase. (457 aa)
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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