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murA murA Ccel_0348 Ccel_0348 Ccel_0367 Ccel_0367 Ccel_0700 Ccel_0700 Ccel_0954 Ccel_0954 Ccel_0969 Ccel_0969 Ccel_0971 Ccel_0971 Ccel_1011 Ccel_1011 Ccel_1036 Ccel_1036 Ccel_1179 Ccel_1179 glmM glmM glmS glmS Ccel_1221 Ccel_1221 Ccel_1229 Ccel_1229 Ccel_1231 Ccel_1231 Ccel_1233 Ccel_1233 Ccel_1234 Ccel_1234 Ccel_1235 Ccel_1235 Ccel_1255 Ccel_1255 Ccel_1259 Ccel_1259 Ccel_1417 Ccel_1417 pgi pgi Ccel_1549 Ccel_1549 Ccel_1550 Ccel_1550 Ccel_1940 Ccel_1940 galT galT murB murB Ccel_2354 Ccel_2354 Ccel_2806 Ccel_2806 Ccel_2807 Ccel_2807 Ccel_2929 Ccel_2929 Ccel_3093 Ccel_3093 Ccel_3221 Ccel_3221 Ccel_3237 Ccel_3237 galK galK murA-2 murA-2 Ccel_3400 Ccel_3400 glgC glgC Ccel_3407 Ccel_3407 Ccel_3412 Ccel_3412 Ccel_3438 Ccel_3438 gmd gmd fcl fcl Ccel_3448 Ccel_3448 Ccel_3452 Ccel_3452
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (420 aa)
Ccel_0348PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; KEGG: cth:Cthe_1961 nucleotidyl transferase. (810 aa)
Ccel_0367TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: drm:Dred_3002 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (337 aa)
Ccel_0700PFAM: ROK family protein; KEGG: cth:Cthe_2938 glucokinase. (325 aa)
Ccel_0954PFAM: PfkB domain protein; KEGG: tpd:Teth39_0632 ribokinase-like domain-containing protein. (321 aa)
Ccel_0969PFAM: NAD-dependent epimerase/dehydratase; polysaccharide biosynthesis protein CapD; Male sterility domain; KEGG: dol:Dole_0520 NAD-dependent epimerase/dehydratase. (342 aa)
Ccel_0971PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: mja:MJ0211 UDP-glucose 4-epimerase (GalE). (309 aa)
Ccel_1011PFAM: glycoside hydrolase family 43; KEGG: cpy:Cphy_0531 alpha-N-arabinofuranosidase; Belongs to the glycosyl hydrolase 43 family. (471 aa)
Ccel_1036PFAM: alpha-L-arabinofuranosidase domain protein; KEGG: gtn:GTNG_1791 alpha-L-arabinofuranosidase. (501 aa)
Ccel_1179TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I; KEGG: cno:NT01CX_1588 mannose-6-phosphate isomerase, class I. (349 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (449 aa)
glmSGlucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (608 aa)
Ccel_1221PFAM: alpha-L-arabinofuranosidase domain protein; KEGG: gtn:GTNG_1791 alpha-L-arabinofuranosidase. (502 aa)
Ccel_1229Carbohydrate binding family 6; PFAM: cellulosome protein dockerin type I; Carbohydrate binding family 6; glycoside hydrolase family 43; SMART: cellulose binding type IV; KEGG: cth:Cthe_1271 carbohydrate-binding family 6 protein; Belongs to the glycosyl hydrolase 43 family. (535 aa)
Ccel_1231Carbohydrate binding family 6; PFAM: cellulosome protein dockerin type I; Carbohydrate binding family 6; glycoside hydrolase family 43; SMART: cellulose binding type IV; KEGG: cth:Cthe_2196 carbohydrate-binding family 6 protein; Belongs to the glycosyl hydrolase 43 family. (524 aa)
Ccel_1233Carbohydrate binding family 6; PFAM: cellulosome protein dockerin type I; Carbohydrate binding family 6; glycoside hydrolase family 43; SMART: cellulose binding type IV; KEGG: bfs:BF0575 putative glycosyl hydrolase/xylanase. (746 aa)
Ccel_1234Carbohydrate binding family 6; PFAM: cellulosome protein dockerin type I; Carbohydrate binding family 6; glycoside hydrolase family 62; SMART: cellulose binding type IV; KEGG: cth:Cthe_2194 carbohydrate-binding family 6 protein. (536 aa)
Ccel_1235Carbohydrate binding family 6; PFAM: cellulosome protein dockerin type I; Carbohydrate binding family 6; glycoside hydrolase family 43; SMART: cellulose binding type IV; KEGG: cth:Cthe_2196 carbohydrate-binding family 6 protein; Belongs to the glycosyl hydrolase 43 family. (509 aa)
Ccel_1255PFAM: alpha-L-arabinofuranosidase domain protein; KEGG: bcl:ABC3371 alpha-L-arabinofuranosidase. (492 aa)
Ccel_1259PFAM: glycoside hydrolase family 39; KEGG: csc:Csac_2409 xylan 1,4-beta-xylosidase. (501 aa)
Ccel_1417PFAM: phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: cth:Cthe_1265 alpha-phosphoglucomutase. (576 aa)
pgiPFAM: phosphoglucose isomerase (PGI); KEGG: cth:Cthe_0217 glucose-6-phosphate isomerase; Belongs to the GPI family. (450 aa)
Ccel_1549KEGG: pmo:Pmob_0233 putative outer membrane protein. (644 aa)
Ccel_1550PFAM: glycoside hydrolase family 18; cellulosome protein dockerin type I; SMART: chitinase II; KEGG: bcl:ABC0646 chitinase; Belongs to the glycosyl hydrolase 18 family. (482 aa)
Ccel_1940PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; KEGG: cth:Cthe_1079 nucleotidyl transferase. (818 aa)
galTPFAM: galactose-1-phosphate uridyl transferase domain protein; KEGG: tte:TTE1929 galactose-1-phosphate uridylyltransferase. (524 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (319 aa)
Ccel_2354Glycosyltransferase 36; PFAM: putative carbohydrate binding; glycosyltransferase 36; glycosyltransferase 36 associated; KEGG: dth:DICTH_0484 N,N'-diacetylchitobiose phosphorylase. (796 aa)
Ccel_2806PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility domain; KEGG: cac:CAC0794 nucleoside-diphosphate-sugar epimerase (UDP-glucose 4-epimerase). (317 aa)
Ccel_2807TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: ckl:CKL_3169 polysaccharide biosynthesis protein. (428 aa)
Ccel_2929TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: bat:BAS5120 UDP-N-acetyl-D-mannosamine dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (424 aa)
Ccel_3093UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (390 aa)
Ccel_3221PFAM: hexokinase; KEGG: hmo:HM1_0763 hexokinase, putative. (431 aa)
Ccel_3237TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: cth:Cthe_0186 UDP-galactose 4-epimerase. (328 aa)
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (397 aa)
murA-2UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (421 aa)
Ccel_3400TIGRFAM: glucose-1-phosphate adenylyltransferase, GlgD subunit; PFAM: Nucleotidyl transferase; KEGG: cth:Cthe_3167 glucose-1-phosphate adenylyltransferase, GlgD subunit; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (372 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (426 aa)
Ccel_3407TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: cth:Cthe_2183 UDP-glucose pyrophosphorylase. (290 aa)
Ccel_3412Glycosyltransferase 36; PFAM: putative carbohydrate binding; glycosyltransferase 36; glycosyltransferase 36 associated; KEGG: dth:DICTH_0484 N,N'-diacetylchitobiose phosphorylase. (824 aa)
Ccel_3438PFAM: glycoside hydrolase family 43; KEGG: oih:OB2087 arabinofuranosidase; Belongs to the glycosyl hydrolase 43 family. (519 aa)
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (345 aa)
fclNAD-dependent epimerase/dehydratase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (310 aa)
Ccel_3448PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: pfu:PF1357 UDP-or dTTP-glucose 4-epimerase or 4-6-dehydratase. (350 aa)
Ccel_3452PFAM: Nucleotidyl transferase; KEGG: csc:Csac_2018 mannose-1-phosphate guanylyltransferase (GDP). (357 aa)
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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