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Ccel_0016 Ccel_0016 fhs fhs Ccel_0138 Ccel_0138 Ccel_0175 Ccel_0175 Ccel_0259 Ccel_0259 Ccel_0413 Ccel_0413 Ccel_0438 Ccel_0438 Ccel_0494 Ccel_0494 Ccel_0553 Ccel_0553 Ccel_0554 Ccel_0554 Ccel_0555 Ccel_0555 Ccel_0556 Ccel_0556 folD folD Ccel_0700 Ccel_0700 Ccel_0932 Ccel_0932 Ccel_0933 Ccel_0933 Ccel_0934 Ccel_0934 accD accD accA accA Ccel_0986 Ccel_0986 Ccel_1164 Ccel_1164 Ccel_1189 Ccel_1189 pgi pgi Ccel_1469 Ccel_1469 Ccel_1537 Ccel_1537 Ccel_1640 Ccel_1640 Ccel_1671 Ccel_1671 Ccel_1672 Ccel_1672 glyA glyA ackA ackA Ccel_2137 Ccel_2137 Ccel_2140 Ccel_2140 Ccel_2176 Ccel_2176 Ccel_2177 Ccel_2177 Ccel_2222 Ccel_2222 pfp pfp eno eno gpmI gpmI tpiA tpiA fabV fabV Ccel_2275 Ccel_2275 Ccel_2373 Ccel_2373 Ccel_2421 Ccel_2421 Ccel_2422 Ccel_2422 Ccel_2473 Ccel_2473 Ccel_2569 Ccel_2569 Ccel_2571 Ccel_2571 Ccel_2576 Ccel_2576 pfkA pfkA Ccel_2918 Ccel_2918 prs prs Ccel_3186 Ccel_3186 Ccel_3191 Ccel_3191 Ccel_3192 Ccel_3192 Ccel_3221 Ccel_3221 Ccel_3325 Ccel_3325 Ccel_3415 Ccel_3415 Ccel_3425 Ccel_3425
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Ccel_0016PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cpy:Cphy_3558 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein. (1183 aa)
fhsPFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: cth:Cthe_2399 formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (556 aa)
Ccel_0138PFAM: malic protein domain protein; malic protein NAD-binding; KEGG: cth:Cthe_0344 malate dehydrogenase. (391 aa)
Ccel_0175PFAM: metalloenzyme domain protein; KEGG: cth:Cthe_2087 metalloenzyme. (297 aa)
Ccel_0259TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase; KEGG: cth:Cthe_2597 ribose-5-phosphate isomerase. (149 aa)
Ccel_0413PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: ypm:YP_3381 pyridoxal-phosphate dependent protein. (326 aa)
Ccel_0438TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane; KEGG: cth:Cthe_2801 carbon-monoxide dehydrogenase, catalytic subunit. (663 aa)
Ccel_0494PFAM: AMP-dependent synthetase and ligase; KEGG: cth:Cthe_0551 AMP-dependent synthetase and ligase. (552 aa)
Ccel_0553PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cth:Cthe_0867 2-oxoglutarate ferredoxin oxidoreductase, delta subunit. (68 aa)
Ccel_0554PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: cth:Cthe_0866 pyruvate flavodoxin/ferredoxin oxidoreductase-like protein. (352 aa)
Ccel_0555PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: cth:Cthe_0865 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin). (248 aa)
Ccel_0556PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: cth:Cthe_0864 2-oxoglutarate ferredoxin oxidoreductase, gamma subunit. (177 aa)
folDTetrahydrofolate dehydrogenase/cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa)
Ccel_0700PFAM: ROK family protein; KEGG: cth:Cthe_2938 glucokinase. (325 aa)
Ccel_0932PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: mja:MJ1229 pyruvate carboxylase subunit A. (513 aa)
Ccel_0933Biotin/lipoyl attachment domain-containing protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (145 aa)
Ccel_0934acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (458 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (288 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (260 aa)
Ccel_0986PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: npu:Npun_R3442 3-hydroxyacyl-CoA dehydrogenase, NAD-binding. (281 aa)
Ccel_1164PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cdf:CD2682 pyruvate-flavodoxin oxidoreductase. (1176 aa)
Ccel_1189TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: csc:Csac_1304 D-3-phosphoglycerate dehydrogenase. (535 aa)
pgiPFAM: phosphoglucose isomerase (PGI); KEGG: cth:Cthe_0217 glucose-6-phosphate isomerase; Belongs to the GPI family. (450 aa)
Ccel_1469PFAM: AMP-dependent synthetase and ligase; KEGG: cth:Cthe_0551 AMP-dependent synthetase and ligase. (559 aa)
Ccel_1537PFAM: ribulose-phosphate 3-epimerase; KEGG: cth:Cthe_0576 ribulose-5-phosphate 3-epimerase. (222 aa)
Ccel_1640TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase; KEGG: msu:MS0383 RpiB protein. (152 aa)
Ccel_1671PFAM: PfkB domain protein; KEGG: cpy:Cphy_0227 ribokinase-like domain-containing protein. (338 aa)
Ccel_1672TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; KEGG: cpy:Cphy_0054 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase. (320 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (412 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
Ccel_2137TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; KEGG: cth:Cthe_1029 phosphotransacetylase. (331 aa)
Ccel_2140Proposed homoserine kinase; TIGRFAM: phosphonopyruvate decarboxylase-related protein; proposed homoserine kinase; PFAM: metalloenzyme domain protein; Homoserine kinase family protein; KEGG: cth:Cthe_1292 phosphoglycerate mutase. (403 aa)
Ccel_2176TIGRFAM: aconitate hydratase; PFAM: aconitate hydratase domain protein; KEGG: cth:Cthe_3158 aconitate hydratase. (642 aa)
Ccel_2177PFAM: pyruvate carboxyltransferase; KEGG: cth:Cthe_3157 pyruvate carboxyltransferase. (457 aa)
Ccel_2222TIGRFAM: ketose-bisphosphate aldolase; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II; KEGG: cth:Cthe_0349 fructose-bisphosphate aldolase. (311 aa)
pfpPhosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (415 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (431 aa)
gpmIPhosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (511 aa)
tpiAPhosphoglycerate kinase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (646 aa)
fabVShort-chain alcohol dehydrogenase; Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA); Belongs to the TER reductase family. (395 aa)
Ccel_2275TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; KEGG: cth:Cthe_0137 glyceraldehyde-3-phosphate dehydrogenase. (335 aa)
Ccel_2373PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: hya:HY04AAS1_1586 predicted phospho-2-dehydro-3-deoxyheptonate aldolase. (267 aa)
Ccel_2421TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: cth:Cthe_3091 tartrate/fumarate subfamily Fe-S type hydro-lyase beta subunit. (185 aa)
Ccel_2422TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; KEGG: cth:Cthe_3090 fumarate hydratase. (280 aa)
Ccel_2473PFAM: dihydropteroate synthase DHPS; KEGG: mta:Moth_1207 methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase. (261 aa)
Ccel_2569TIGRFAM: pyruvate kinase; PFAM: PEP-utilising protein mobile region; Pyruvate kinase barrel; Pyruvate kinase alpha/beta; KEGG: csc:Csac_1831 pyruvate kinase; Belongs to the pyruvate kinase family. (580 aa)
Ccel_2571PFAM: Citrate synthase; KEGG: mta:Moth_1122 methylcitrate synthase; Belongs to the citrate synthase family. (450 aa)
Ccel_2576TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: ckl:CKL_0546 isocitrate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (402 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (327 aa)
Ccel_2918TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane; KEGG: amt:Amet_1177 carbon-monoxide dehydrogenase, catalytic subunit. (710 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (319 aa)
Ccel_3186TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cpy:Cphy_0011 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. (310 aa)
Ccel_3191PFAM: PfkB domain protein; KEGG: ote:Oter_4259 ribokinase-like domain-containing protein. (366 aa)
Ccel_3192TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; KEGG: amt:Amet_1261 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase. (214 aa)
Ccel_3221PFAM: hexokinase; KEGG: hmo:HM1_0763 hexokinase, putative. (431 aa)
Ccel_3325TIGRFAM: serine O-acetyltransferase; KEGG: cth:Cthe_2066 serine O-acetyltransferase. (243 aa)
Ccel_3415Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (662 aa)
Ccel_3425PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: ppd:Ppro_2951 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (319 aa)
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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