STRINGSTRING
gpmI gpmI tpiA tpiA pgk pgk kdpD kdpD CUP02802.1 CUP02802.1 eno_2 eno_2 pdxK pdxK tmk tmk ypdA ypdA pgk/tpi pgk/tpi dhaK_2 dhaK_2 dhaL_2 dhaL_2 glpK_5 glpK_5 CUP13672.1 CUP13672.1 phoR_3 phoR_3 araB_3 araB_3 cobU cobU CUP20790.1 CUP20790.1 coaX coaX glpK_4 glpK_4 araB_2 araB_2 arcC1_2 arcC1_2 ackA ackA pykF pykF thiN thiN prkC_12 prkC_12 gmk_2 gmk_2 yjbM yjbM adrA_3 adrA_3 thiD thiD thiM thiM relA_1 relA_1 lysC lysC glcK glcK gmk_1 gmk_1 aroL aroL argB argB senX3_1 senX3_1 cmk cmk CUN67459.1 CUN67459.1 arlS_1 arlS_1 CUN69120.1 CUN69120.1 walK_1 walK_1 pgi pgi relA_2 relA_2 yehU_1 yehU_1 pyk pyk graS graS selD selD xylB xylB phoR_1 phoR_1 ywaC_1 ywaC_1 galK galK prkC_1 prkC_1 spoIIAB spoIIAB prkC_2 prkC_2 prkC_3 prkC_3 ppk_2 ppk_2 prkC_4 prkC_4 CUN97447.1 CUN97447.1 spkF spkF prkC_5 prkC_5 pknB_1 pknB_1 prkC_6 prkC_6 CUN98435.1 CUN98435.1 prkC_7 prkC_7 prkC_8 prkC_8 lacC lacC desK desK hprK hprK pfkA_1 pfkA_1 mprB mprB phoR_2 phoR_2 yehU_2 yehU_2 CUO11267.1 CUO11267.1 CUO11411.1 CUO11411.1 creC creC arlS_2 arlS_2 dagK dagK CUO12495.1 CUO12495.1 eno_1 eno_1 pknB_2 pknB_2 prkC_9 prkC_9 pknB_3 pknB_3 prkC_10 prkC_10 pknB_4 pknB_4 prkC_11 prkC_11 ywaC_2 ywaC_2 proB proB arlS_3 arlS_3 yehU_3 yehU_3 CUO23056.1 CUO23056.1 mtnK_1 mtnK_1 mtnK_2 mtnK_2 CUO24033.1 CUO24033.1 CUO24239.1 CUO24239.1 CUO24291.1 CUO24291.1 mtnK_3 mtnK_3 CUO27008.1 CUO27008.1 glpK_1 glpK_1 ispE ispE CUO28364.1 CUO28364.1 pfkA_2 pfkA_2 rbsK rbsK CUO31068.1 CUO31068.1 ptsI ptsI araB_1 araB_1 manX manX luxQ_1 luxQ_1 ppnK ppnK CUO43893.1 CUO43893.1 CUO44485.1 CUO44485.1 lsrK lsrK glpK_2 glpK_2 lyx lyx walK_2 walK_2 baeS baeS ywaC_3 ywaC_3 ppdK ppdK prs prs CUO64889.1 CUO64889.1 glpK_3 glpK_3 pyrH pyrH ribF ribF CUO69582.1 CUO69582.1 coaE coaE ppk_1 ppk_1 sulD sulD arcC1_1 arcC1_1 ywaC_4 ywaC_4 senX3_2 senX3_2 adk adk pfkA1 pfkA1 CUO98017.1 CUO98017.1 prkC_13 prkC_13 dhaL_1 dhaL_1 dhaK_1 dhaK_1 CUO93771.1 CUO93771.1 CUO93742.1 CUO93742.1 cpsD cpsD
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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gpmI2%2C3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (514 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (249 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (403 aa)
kdpDSensor protein KdpD. (524 aa)
CUP02802.1Cytidylate kinase. (205 aa)
eno_2Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa)
pdxKPyridoxine kinase; Belongs to the pyridoxine kinase family. (273 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (209 aa)
ypdAInner membrane protein ypdA. (631 aa)
pgk/tpiBifunctional PGK/TIM. (257 aa)
dhaK_2PTS-dependent dihydroxyacetone kinase%2C dihydroxyacetone-binding subunit dhaK. (338 aa)
dhaL_2PTS-dependent dihydroxyacetone kinase%2C ADP-binding subunit dhaL. (216 aa)
glpK_5Glycerol kinase. (494 aa)
CUP13672.1Uncharacterised protein. (1858 aa)
phoR_3Alkaline phosphatase synthesis sensor protein phoR. (521 aa)
araB_3Ribulokinase. (554 aa)
cobUAdenosylcobinamide kinase. (185 aa)
CUP20790.1Cytidylate kinase. (198 aa)
coaXType III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (257 aa)
glpK_4Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (498 aa)
araB_2Ribulokinase; Belongs to the FGGY kinase family. (517 aa)
arcC1_2Carbamate kinase 1; Belongs to the carbamate kinase family. (309 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (411 aa)
pykFPyruvate kinase I; Belongs to the pyruvate kinase family. (358 aa)
thiNThiamine pyrophosphokinase. (227 aa)
prkC_12Serine/threonine-protein kinase PrkC. (698 aa)
gmk_2Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (215 aa)
yjbMGTP pyrophosphokinase yjbM. (266 aa)
adrA_3Probable diguanylate cyclase AdrA. (455 aa)
thiDHydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (483 aa)
thiMHydroxyethylthiazole kinase. (287 aa)
relA_1GTP pyrophosphokinase. (183 aa)
lysCAspartokinase 2; Belongs to the aspartokinase family. (402 aa)
glcKGlucokinase. (309 aa)
gmk_1Guanylate kinase. (357 aa)
aroLShikimate kinase 2; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (167 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (298 aa)
senX3_1Signal-transduction histidine kinase senX3. (453 aa)
cmkCytidylate kinase. (221 aa)
CUN67459.1Hpt domain. (115 aa)
arlS_1Signal transduction histidine-protein kinase ArlS. (382 aa)
CUN69120.1Predicted sensor domain. (430 aa)
walK_1Sensor protein kinase walK. (386 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (527 aa)
relA_2GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (758 aa)
yehU_1Probable sensor-like histidine kinase YehU. (627 aa)
pykPyruvate kinase; Belongs to the pyruvate kinase family. (473 aa)
graSSensor histidine kinase graS. (345 aa)
selDSelenide%2C water dikinase; Synthesizes selenophosphate from selenide and ATP. (342 aa)
xylBXylulose kinase. (512 aa)
phoR_1Alkaline phosphatase synthesis sensor protein phoR. (437 aa)
ywaC_1GTP pyrophosphokinase ywaC. (223 aa)
galKGalactokinase; Belongs to the GHMP kinase family. (424 aa)
prkC_1Serine/threonine-protein kinase PrkC. (581 aa)
spoIIABAnti-sigma F factor. (153 aa)
prkC_2Serine/threonine-protein kinase PrkC. (604 aa)
prkC_3Serine/threonine-protein kinase PrkC. (744 aa)
ppk_2Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (681 aa)
prkC_4Serine/threonine-protein kinase PrkC. (699 aa)
CUN97447.1Uncharacterised protein. (519 aa)
spkFSerine/threonine-protein kinase F. (626 aa)
prkC_5Serine/threonine-protein kinase PrkC. (304 aa)
pknB_1Serine/threonine-protein kinase pknB. (649 aa)
prkC_6Serine/threonine-protein kinase PrkC. (454 aa)
CUN98435.1Histidine kinase-%2C DNA gyrase B-%2C and HSP90-like ATPase. (224 aa)
prkC_7Serine/threonine-protein kinase PrkC. (535 aa)
prkC_8Serine/threonine-protein kinase PrkC. (610 aa)
lacCTagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (302 aa)
desKSensor histidine kinase desK. (458 aa)
hprKHPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon [...] (314 aa)
pfkA_16-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (330 aa)
mprBSignal transduction histidine-protein kinase/phosphatase mprB. (393 aa)
phoR_2Alkaline phosphatase synthesis sensor protein phoR. (301 aa)
yehU_2Probable sensor-like histidine kinase YehU. (585 aa)
CUO11267.1Cytidylate kinase. (198 aa)
CUO11411.1Uncharacterized protein related to capsule biosynthesis enzymes. (386 aa)
creCSensor protein CreC. (472 aa)
arlS_2Signal transduction histidine-protein kinase ArlS. (459 aa)
dagKDiacylglycerol kinase. (300 aa)
CUO12495.1Cytidylate kinase. (198 aa)
eno_1Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (431 aa)
pknB_2Serine/threonine-protein kinase pknB. (623 aa)
prkC_9Serine/threonine-protein kinase PrkC. (719 aa)
pknB_3Serine/threonine-protein kinase pknB. (482 aa)
prkC_10Serine/threonine-protein kinase PrkC. (676 aa)
pknB_4Serine/threonine-protein kinase pknB. (782 aa)
prkC_11Serine/threonine-protein kinase PrkC. (731 aa)
ywaC_2GTP pyrophosphokinase ywaC. (264 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (257 aa)
arlS_3Signal transduction histidine-protein kinase ArlS. (455 aa)
yehU_3Probable sensor-like histidine kinase YehU. (411 aa)
CUO23056.1Uncharacterised protein. (517 aa)
mtnK_1Methylthioribose kinase. (407 aa)
mtnK_2Methylthioribose kinase. (417 aa)
CUO24033.1Cytidylate kinase. (320 aa)
CUO24239.1Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains. (451 aa)
CUO24291.1Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains. (397 aa)
mtnK_3Methylthioribose kinase. (409 aa)
CUO27008.1Cytidylate kinase. (201 aa)
glpK_1Glycerol kinase. (505 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (325 aa)
CUO28364.1Spore coat protein%2C CotS family. (334 aa)
pfkA_26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (357 aa)
rbsKRibokinase. (307 aa)
CUO31068.1Uncharacterised protein. (440 aa)
ptsIPhosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (569 aa)
araB_1Ribulokinase. (556 aa)
manXEIIAB-Man. (329 aa)
luxQ_1Autoinducer 2 sensor kinase/phosphatase luxQ. (256 aa)
ppnKProbable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (278 aa)
CUO43893.1Sensory histidine kinase DcuS. (275 aa)
CUO44485.1Signal transduction histidine kinase. (441 aa)
lsrKAutoinducer 2 kinase LsrK. (510 aa)
glpK_2Glycerol kinase. (495 aa)
lyxL-xylulose/3-keto-L-gulonate kinase. (506 aa)
walK_2Sensor protein kinase walK. (354 aa)
baeSSignal transduction histidine-protein kinase BaeS. (347 aa)
ywaC_3GTP pyrophosphokinase ywaC. (226 aa)
ppdKPyruvate%2C phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (876 aa)
prsRibose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (397 aa)
CUO64889.1Uncharacterised protein. (226 aa)
glpK_3Glycerol kinase. (493 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (237 aa)
ribFRiboflavin biosynthesis protein ribF; Belongs to the ribF family. (309 aa)
CUO69582.1Cytidylate kinase. (206 aa)
coaEDephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (210 aa)
ppk_1Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (716 aa)
sulDBifunctional folate synthesis protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (274 aa)
arcC1_1Carbamate kinase 1. (313 aa)
ywaC_4GTP pyrophosphokinase ywaC. (204 aa)
senX3_2Signal-transduction histidine kinase senX3. (421 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (213 aa)
pfkA16-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (408 aa)
CUO98017.1Protein kinase domain. (242 aa)
prkC_13Serine/threonine-protein kinase PrkC. (406 aa)
dhaL_1PTS-dependent dihydroxyacetone kinase%2C ADP-binding subunit dhaL. (207 aa)
dhaK_1PTS-dependent dihydroxyacetone kinase%2C dihydroxyacetone-binding subunit dhaK. (332 aa)
CUO93771.1Uncharacterised protein. (96 aa)
CUO93742.1Cytidylate kinase. (195 aa)
cpsDTyrosine-protein kinase CpsD. (245 aa)
Your Current Organism:
Anaerobutyricum hallii
NCBI taxonomy Id: 39488
Other names: A. hallii, ATCC 27751, DSM 3353, Eubacterium hallii, VPI B4-27
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