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| | ftsH_3 | ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (604 aa) |
| | CUP20007.1 | Uncharacterized protein conserved in bacteria. (161 aa) |
| | ppaC | Manganese-dependent inorganic pyrophosphatase. (551 aa) |
| | CUP16289.1 | Bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon. (832 aa) |
| | ppx | Exopolyphosphatase. (307 aa) |
| | clpA | ATP-dependent Clp protease ATP-binding subunit ClpA. (627 aa) |
| | pcrA_2 | ATP-dependent DNA helicase pcrA. (738 aa) |
| | rarA | Replication-associated recombination protein A. (441 aa) |
| | ffh | Fifty-four homolog; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (451 aa) |
| | CUP03319.1 | Uncharacterised protein. (1024 aa) |
| | hypF | Carbamoyltransferase hypF; Belongs to the carbamoyltransferase HypF family. (809 aa) |
| | CUO98238.1 | Uncharacterised protein. (475 aa) |
| | copA_2 | Probable copper-importing P-type ATPase A. (845 aa) |
| | CUO08194.1 | Uncharacterised protein. (178 aa) |
| | soj_3 | Sporulation initiation inhibitor protein soj. (261 aa) |
| | cysNC | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family. (609 aa) |
| | CUO12776.1 | ATPase family associated with various cellular activities (AAA). (557 aa) |
| | hppA1 | Putative K(+)-stimulated pyrophosphate-energized sodium pump; Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily. (662 aa) |
| | CUO17292.1 | Adenosine nucleotide hydrolase NudE. (210 aa) |
| | recG_2 | ATP-dependent DNA helicase recG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (673 aa) |
| | ftsH_2 | ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (634 aa) |
| | mutS2 | MutS2 protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (791 aa) |
| | yccX | Acylphosphatase. (96 aa) |
| | prfC | Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (529 aa) |
| | CUO28766.1 | Uncharacterised protein. (540 aa) |
| | mutL | DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (731 aa) |
| | minD | Cell division inhibitor MinD. (263 aa) |
| | yjcD_2 | Putative ATP-dependent DNA helicase yjcD. (667 aa) |
| | uppP | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (273 aa) |
| | CUO38998.1 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (194 aa) |
| | smc | Chromosome partition protein Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1187 aa) |
| | soj_2 | Sporulation initiation inhibitor protein soj. (256 aa) |
| | ftsY | Cell division protein FtsY homolog; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (313 aa) |
| | ruvA | Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (230 aa) |
| | ruvB | Holliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (334 aa) |
| | obg | Spo0B-associated GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (429 aa) |
| | soj_4 | Sporulation initiation inhibitor protein soj. (256 aa) |
| | dnaB | Replicative DNA helicase. (337 aa) |
| | CUO47714.1 | AAA domain (dynein-related subfamily). (303 aa) |
| | pcrA_1 | ATP-dependent DNA helicase pcrA. (641 aa) |
| | soj_5 | Sporulation initiation inhibitor protein soj. (239 aa) |
| | CUO56728.1 | Uncharacterised protein. (146 aa) |
| | soj_6 | Sporulation initiation inhibitor protein soj. (239 aa) |
| | mcrB | 5-methylcytosine-specific restriction enzyme B. (634 aa) |
| | cysN | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (549 aa) |
| | dnaC_2 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (449 aa) |
| | addA | ATP-dependent helicase/nuclease subunit A. (1221 aa) |
| | addB | ATP-dependent helicase/deoxyribonuclease subunit B; ATP-dependent DNA helicase. (1134 aa) |
| | infB | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (835 aa) |
| | era | Bex protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (301 aa) |
| | CUO73258.1 | Guanosine pentaphosphate phosphohydrolase. (511 aa) |
| | scpB | Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (190 aa) |
| | clpB | Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (863 aa) |
| | CUO79725.1 | DNA-dependent helicase II. (668 aa) |
| | CUO80624.1 | Plasmid recombination enzyme. (416 aa) |
| | tetM_1 | Tetracycline resistance protein tetM from transposon Tn916. (398 aa) |
| | tetM_2 | Tetracycline resistance protein tetM from transposon Tn916. (468 aa) |
| | CUO82331.1 | Predicted ATPase. (457 aa) |
| | spoIVA | Stage IV sporulation protein A. (489 aa) |
| | rsgA | Putative ribosome biogenesis GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (292 aa) |
| | engD | GTP-dependent nucleic acid-binding protein engD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (365 aa) |
| | ftsZ | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (384 aa) |
| | cadA | Cadmium%2C zinc and cobalt-transporting ATPase. (1120 aa) |
| | mnmE_1 | tRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (465 aa) |
| | maf | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (191 aa) |
| | CUO04972.1 | Antiporter inner membrane protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (276 aa) |
| | ftsH_1 | ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (677 aa) |
| | CUO03146.1 | Uncharacterised protein. (1489 aa) |
| | CUO01301.1 | Uncharacterised protein. (51 aa) |
| | gph_2 | Phosphoglycolate phosphatase. (215 aa) |
| | hflX | GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (432 aa) |
| | guaA_2 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. (515 aa) |
| | soj_1 | Sporulation initiation inhibitor protein soj. (261 aa) |
| | lon1_2 | Lon protease 1. (494 aa) |
| | fusA_2 | Vegetative protein 19. (887 aa) |
| | recD_2 | Exodeoxyribonuclease V alpha chain; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (736 aa) |
| | yncF | Probable deoxyuridine 5'-triphosphate nucleotidohydrolase yncF; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (145 aa) |
| | htpG | High temperature protein G. (660 aa) |
| | uvrB | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (664 aa) |
| | uvrA | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (950 aa) |
| | copA_1 | Copper-exporting P-type ATPase A. (699 aa) |
| | fusA_1 | Vegetative protein 19; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (709 aa) |
| | tuf | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (397 aa) |
| | ravA | ATPase ravA. (315 aa) |
| | typA | Tyrosine phosphorylated protein A. (611 aa) |
| | CUN71718.1 | Magnesium-transporting ATPase. (538 aa) |
| | clpX_3 | ATP-dependent Clp protease ATP-binding subunit ClpX. (538 aa) |
| | lon1_1 | Lon protease 1; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (768 aa) |
| | clpX_2 | ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (432 aa) |
| | gph_1 | Phosphoglycolate phosphatase. (220 aa) |
| | lepA | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (604 aa) |
| | yjcD_1 | Putative ATP-dependent DNA helicase yjcD. (613 aa) |
| | recD_1 | Exodeoxyribonuclease V alpha chain. (690 aa) |
| | clpX_1 | ATP-dependent Clp protease ATP-binding subunit ClpX. (363 aa) |
| | recG_1 | ATP-dependent DNA helicase recG. (663 aa) |
| | clpC | Negative regulator of genetic competence ClpC/MecB; Belongs to the ClpA/ClpB family. (820 aa) |
| | CUN47392.1 | Predicted ATP-binding protein involved in virulence. (175 aa) |
| | CUN47354.1 | Probable DNA double-strand break repair Rad50 ATPase. (88 aa) |
| | fus | Elongation factor G. (697 aa) |
