STRINGSTRING
recG_2 recG_2 topB_1 topB_1 recG_1 recG_1 recD_1 recD_1 topB_2 topB_2 yjcD_1 yjcD_1 sspC2 sspC2 recD_2 recD_2 recQ recQ topB_3 topB_3 CUN93815.1 CUN93815.1 mobA mobA gyrA_1 gyrA_1 gyrB gyrB CUO09131.1 CUO09131.1 CUO10151.1 CUO10151.1 CUO30092.1 CUO30092.1 yjcD_2 yjcD_2 ruvA ruvA ruvB ruvB dnaB dnaB pcrA_1 pcrA_1 CUO52258.1 CUO52258.1 CUO55740.1 CUO55740.1 dnaC_2 dnaC_2 addA addA addB addB CUO79725.1 CUO79725.1 CUO80015.1 CUO80015.1 CUO80660.1 CUO80660.1 CUO81533.1 CUO81533.1 CUO82618.1 CUO82618.1 priA priA CUO88108.1 CUO88108.1 pcrA_2 pcrA_2 topB_4 topB_4 parE parE gyrA_2 gyrA_2 comM comM topA topA CUP16289.1 CUP16289.1 CUP17048.1 CUP17048.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
recG_2ATP-dependent DNA helicase recG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (673 aa)
topB_1DNA topoisomerase 3. (723 aa)
recG_1ATP-dependent DNA helicase recG. (663 aa)
recD_1Exodeoxyribonuclease V alpha chain. (690 aa)
topB_2DNA topoisomerase 3. (827 aa)
yjcD_1Putative ATP-dependent DNA helicase yjcD. (613 aa)
sspC2SSP-3. (73 aa)
recD_2Exodeoxyribonuclease V alpha chain; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (736 aa)
recQATP-dependent DNA helicase recQ. (667 aa)
topB_3DNA topoisomerase 3. (690 aa)
CUN93815.1DNA repair protein RadA. (635 aa)
mobADNA strand transferase. (575 aa)
gyrA_1DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (852 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (643 aa)
CUO09131.1Relaxase/Mobilisation nuclease domain. (514 aa)
CUO10151.1Conjugal transfer relaxase TraA. (573 aa)
CUO30092.1Small%2C acid-soluble spore proteins%2C alpha/beta type. (70 aa)
yjcD_2Putative ATP-dependent DNA helicase yjcD. (667 aa)
ruvAHolliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (230 aa)
ruvBHolliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (334 aa)
dnaBReplicative DNA helicase. (337 aa)
pcrA_1ATP-dependent DNA helicase pcrA. (641 aa)
CUO52258.1Conjugal transfer relaxase TraA. (573 aa)
CUO55740.1Relaxase/Mobilisation nuclease domain. (460 aa)
dnaC_2Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (449 aa)
addAATP-dependent helicase/nuclease subunit A. (1221 aa)
addBATP-dependent helicase/deoxyribonuclease subunit B; ATP-dependent DNA helicase. (1134 aa)
CUO79725.1DNA-dependent helicase II. (668 aa)
CUO80015.1Relaxase/Mobilisation nuclease domain. (357 aa)
CUO80660.1DNA repair protein RadA. (276 aa)
CUO81533.1Relaxase/Mobilisation nuclease domain. (452 aa)
CUO82618.1Uncharacterised protein. (1250 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (750 aa)
CUO88108.1Type IV secretory pathway%2C VirB4 components. (1109 aa)
pcrA_2ATP-dependent DNA helicase pcrA. (738 aa)
topB_4DNA topoisomerase 3; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (720 aa)
parEDNA topoisomerase 4 subunit B. (638 aa)
gyrA_2DNA gyrase subunit A. (754 aa)
comMCompetence protein ComM. (550 aa)
topADNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (691 aa)
CUP16289.1Bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon. (832 aa)
CUP17048.1AIPR protein. (70 aa)
Your Current Organism:
Anaerobutyricum hallii
NCBI taxonomy Id: 39488
Other names: A. hallii, ATCC 27751, DSM 3353, Eubacterium hallii, VPI B4-27
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