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panC panC guaA_2 guaA_2 etfB_1 etfB_1 etfA_1 etfA_1 ttcA_1 ttcA_1 nadE nadE leuS leuS guaA_1 guaA_1 trpS2 trpS2 argG argG glnS glnS cysS cysS mnmA mnmA gltX gltX CUO93907.1 CUO93907.1 queC queC CUO89383.1 CUO89383.1 tmcAL tmcAL ribF ribF cysD_2 cysD_2 thiI thiI ttcA_2 ttcA_2 nadD nadD tyrS tyrS etfA_2 etfA_2 etfB_2 etfB_2 metG metG lysS lysS ileS ileS coaD coaD cysD_1 cysD_1 argS argS valS valS
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (280 aa)
guaA_2GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. (515 aa)
etfB_1Electron transfer flavoprotein small subunit. (261 aa)
etfA_1Electron transfer flavoprotein large subunit. (346 aa)
ttcA_1tRNA 2-thiocytidine biosynthesis protein TtcA; Belongs to the TtcA family. (390 aa)
nadEGlutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (643 aa)
leuSLeucine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (803 aa)
guaA_1GMP synthase [glutamine-hydrolyzing]. (269 aa)
trpS2Tryptophan--tRNA ligase 2; Belongs to the class-I aminoacyl-tRNA synthetase family. (353 aa)
argGArgininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (409 aa)
glnSGlutamine--tRNA ligase. (555 aa)
cysSCysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (464 aa)
mnmAtRNA-specific 2-thiouridylase mnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (354 aa)
gltXGlutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (483 aa)
CUO93907.1DUF218 domain. (250 aa)
queC7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). (221 aa)
CUO89383.1DUF218 domain. (213 aa)
tmcALProtein of uncharacterised function (DUF795); Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. (456 aa)
ribFRiboflavin biosynthesis protein ribF; Belongs to the ribF family. (309 aa)
cysD_2Sulfate adenylyltransferase subunit 2. (300 aa)
thiIProbable tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (394 aa)
ttcA_2tRNA 2-thiocytidine biosynthesis protein TtcA; Belongs to the TtcA family. (241 aa)
nadDProbable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (214 aa)
tyrSTyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (410 aa)
etfA_2Electron transfer flavoprotein large subunit. (334 aa)
etfB_2Electron transfer flavoprotein small subunit. (267 aa)
metGMethionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (654 aa)
lysSLysine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (681 aa)
ileSIsoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1052 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (160 aa)
cysD_1Sulfate adenylyltransferase subunit 2. (300 aa)
argSArginine--tRNA ligase. (564 aa)
valSValine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (880 aa)
Your Current Organism:
Anaerobutyricum hallii
NCBI taxonomy Id: 39488
Other names: A. hallii, ATCC 27751, DSM 3353, Eubacterium hallii, VPI B4-27
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