(5 nodes) Acetolactate synthase activity network (Eubacterium siraeum)

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	tdcB	L-threonine dehydratase catabolic TdcB; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (397 aa)
	ilvH_1	Acetolactate synthase small subunit. (163 aa)
	ilvB_1	Acetolactate synthase large subunit. (543 aa)
	ilvH_2	Acetolactate synthase small subunit. (157 aa)
	ilvB_2	Acetolactate synthase large subunit. (564 aa)

Your Current Organism:

Eubacterium siraeum

NCBI taxonomy Id: 39492
Other names: ATCC 29066, DSM 15702, DSM 3996, [. siraeum, [Eubacterium] siraeum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ilvB_1	ilvB_2	ERS852540_01603	ERS852540_01680	Acetolactate synthase large subunit.	Acetolactate synthase large subunit.	0.910
ilvB_1	ilvH_1	ERS852540_01603	ERS852540_01602	Acetolactate synthase large subunit.	Acetolactate synthase small subunit.	0.999
ilvB_1	ilvH_2	ERS852540_01603	ERS852540_01679	Acetolactate synthase large subunit.	Acetolactate synthase small subunit.	0.996
ilvB_1	tdcB	ERS852540_01603	ERS852540_01475	Acetolactate synthase large subunit.	L-threonine dehydratase catabolic TdcB; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	0.962
ilvB_2	ilvB_1	ERS852540_01680	ERS852540_01603	Acetolactate synthase large subunit.	Acetolactate synthase large subunit.	0.910
ilvB_2	ilvH_1	ERS852540_01680	ERS852540_01602	Acetolactate synthase large subunit.	Acetolactate synthase small subunit.	0.997
ilvB_2	ilvH_2	ERS852540_01680	ERS852540_01679	Acetolactate synthase large subunit.	Acetolactate synthase small subunit.	0.999
ilvB_2	tdcB	ERS852540_01680	ERS852540_01475	Acetolactate synthase large subunit.	L-threonine dehydratase catabolic TdcB; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	0.962
ilvH_1	ilvB_1	ERS852540_01602	ERS852540_01603	Acetolactate synthase small subunit.	Acetolactate synthase large subunit.	0.999
ilvH_1	ilvB_2	ERS852540_01602	ERS852540_01680	Acetolactate synthase small subunit.	Acetolactate synthase large subunit.	0.997
ilvH_1	ilvH_2	ERS852540_01602	ERS852540_01679	Acetolactate synthase small subunit.	Acetolactate synthase small subunit.	0.909
ilvH_1	tdcB	ERS852540_01602	ERS852540_01475	Acetolactate synthase small subunit.	L-threonine dehydratase catabolic TdcB; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	0.977
ilvH_2	ilvB_1	ERS852540_01679	ERS852540_01603	Acetolactate synthase small subunit.	Acetolactate synthase large subunit.	0.996
ilvH_2	ilvB_2	ERS852540_01679	ERS852540_01680	Acetolactate synthase small subunit.	Acetolactate synthase large subunit.	0.999
ilvH_2	ilvH_1	ERS852540_01679	ERS852540_01602	Acetolactate synthase small subunit.	Acetolactate synthase small subunit.	0.909
ilvH_2	tdcB	ERS852540_01679	ERS852540_01475	Acetolactate synthase small subunit.	L-threonine dehydratase catabolic TdcB; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	0.977
tdcB	ilvB_1	ERS852540_01475	ERS852540_01603	L-threonine dehydratase catabolic TdcB; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	Acetolactate synthase large subunit.	0.962
tdcB	ilvB_2	ERS852540_01475	ERS852540_01680	L-threonine dehydratase catabolic TdcB; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	Acetolactate synthase large subunit.	0.962
tdcB	ilvH_1	ERS852540_01475	ERS852540_01602	L-threonine dehydratase catabolic TdcB; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	Acetolactate synthase small subunit.	0.977
tdcB	ilvH_2	ERS852540_01475	ERS852540_01679	L-threonine dehydratase catabolic TdcB; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	Acetolactate synthase small subunit.	0.977