STRINGSTRING
cobO cobO cobD cobD cobB cobB cobO-2 cobO-2 BAG43578.1 BAG43578.1 cobJ cobJ cobI cobI cobH cobH cobL cobL cbiD cbiD cobK cobK cobM cobM cobQ cobQ cobP cobP cobD-2 cobD-2 cobC cobC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cobOcob(I)alamin adenosyltransferase; COG2096: Uncharacterized conserved protein, Ralstonia solanacearum; KEGG, K00798; Belongs to the Cob(I)alamin adenosyltransferase family. (183 aa)
cobDAdenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (312 aa)
cobBHydrogenobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (434 aa)
cobO-2cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (200 aa)
BAG43578.1Cobalamin biosynthesis protein. (125 aa)
cobJCOG1010: Precorrin-3B methylase, Pseudomonas aeruginosa; KEGG, K00594. (571 aa)
cobIPrecorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. (244 aa)
cobHprecorrin-8X methylmutase; COG2082: Precorrin isomerase, Pseudomonas aeruginosa; KEGG, K01833. (208 aa)
cobLprecorrin-6Y C5,15-methyltransferase; COG2242: Precorrin-6B methylase 2, Pseudomonas aeruginosa; KEGG, K00595. (412 aa)
cbiDCobalamin biosynthesis protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (362 aa)
cobKCOG2099: Precorrin-6x reductase, Pseudomonas aeruginosa; KEGG, K00221. (243 aa)
cobMCOG2875: Precorrin-4 methylase, Pseudomonas aeruginosa; KEGG, K00596. (242 aa)
cobQAdenosylcobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (501 aa)
cobPAdenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (186 aa)
cobD-2Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (314 aa)
cobCCobalamin biosynthetic protein; COG0079: Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase, Ralstonia solanacearum; CobC protein; KEGG, K02225. (339 aa)
Your Current Organism:
Burkholderia multivorans
NCBI taxonomy Id: 395019
Other names: B. multivorans ATCC 17616, Burkholderia multivorans ATCC 17616, Burkholderia multivorans str. ATCC 17616, Burkholderia multivorans strain ATCC 17616
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.