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BAG42068.1 BAG42068.1 serA serA serA-2 serA-2 gph gph glcD glcD glcD-2 glcD-2 glcD-3 glcD-3 dld dld BAG42645.1 BAG42645.1 serC serC ykgG ykgG gyaR gyaR gph-3 gph-3 lldD lldD BAG43634.1 BAG43634.1 gcl gcl gip gip garR garR glxK glxK garR-2 garR-2 aceA aceA glcB glcB BAG44021.1 BAG44021.1 BAG44022.1 BAG44022.1 BAG44587.1 BAG44587.1 BAG45666.1 BAG45666.1 gph-5 gph-5 gph-6 gph-6 serA-4 serA-4 glcB-2 glcB-2 BAG47280.1 BAG47280.1 BAG47524.1 BAG47524.1 ykgG-2 ykgG-2 BAG47526.1 BAG47526.1 BAG47527.1 BAG47527.1 cydB-3 cydB-3 cydA-3 cydA-3 BAG47544.1 BAG47544.1 lldD-2 lldD-2 fdh-5 fdh-5
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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BAG42068.1LctP family lactate transporter; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (554 aa)
serACOG0111: Phosphoglycerate dehydrogenase and related dehydrogenases, Ralstonia solanacearum; KEGG, K00058; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (337 aa)
serA-2COG0111: Phosphoglycerate dehydrogenase and related dehydrogenases, Ralstonia solanacearum; KEGG, K00058. (313 aa)
gphPhosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (256 aa)
glcD(S)-2-hydroxy-acid oxidase; COG0247: Fe-S oxidoreductase, Ralstonia solanacearum; KEGG, K00104. (408 aa)
glcD-2(S)-2-hydroxy-acid oxidase; COG0277: FAD/FMN-containing dehydrogenases, Ralstonia solanacearum; KEGG, K00104. (362 aa)
glcD-3(S)-2-hydroxy-acid oxidase; COG0277: FAD/FMN-containing dehydrogenases, Ralstonia solanacearum; KEGG, K00104. (497 aa)
dldCytochrome D-lactate dehydrogenase; COG0277: FAD/FMN-containing dehydrogenases, Ralstonia solanacearum; KEGG, K00102. (469 aa)
BAG42645.1Aminotransferase; COG0075: Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase, Vibrio cholerae; KEGG, K00839. (403 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (360 aa)
ykgGCOG1556: Uncharacterized conserved protein, Ralstonia solanacearum; KEGG, K00782. (220 aa)
gyaRGlyoxylate reductase; COG1052: Lactate dehydrogenase and related dehydrogenases, Ralstonia solanacearum; KEGG, K00015; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)
gph-3COG0546: Predicted phosphatases, Ralstonia solanacearum; KEGG, K01091. (219 aa)
lldDCOG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases, Mycobacterium leprae; KEGG, K00101. (405 aa)
BAG43634.1Gluconate 2-dehydrogenase; COG1052: Lactate dehydrogenase and related dehydrogenases, Escherichia coli K12; KEGG, K00090; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (321 aa)
gclTartronate-semialdehyde synthase; COG3960: Glyoxylate carboligase, Pseudomonas aeruginosa; KEGG, K01608; Belongs to the TPP enzyme family. (591 aa)
gipCOG3622: Hydroxypyruvate isomerase, Ralstonia solanacearum; KEGG, K01816; Belongs to the hyi family. (269 aa)
garR2-hydroxy-3-oxopropionate reductase; COG2084: 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases, Mesorhizobium loti; KEGG, K00042. (296 aa)
glxKCOG1929: Glycerate kinase, Pseudomonas aeruginosa; KEGG, K00865; Belongs to the glycerate kinase type-1 family. (381 aa)
garR-22-hydroxy-3-oxopropionate reductase; COG2084: 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases, Pseudomonas aeruginosa; KEGG, K00042. (296 aa)
aceACOG2224: Isocitrate lyase, Ralstonia solanacearum; KEGG, K01637. (435 aa)
glcBCOG2225: Malate synthase, Ralstonia solanacearum; KEGG, K01638. (530 aa)
BAG44021.1COG1139: Uncharacterized conserved protein containing a ferredoxin-like domain, Ralstonia solanacearum; contains a ferredoxin-like domain. (470 aa)
BAG44022.1COG0247: Fe-S oxidoreductase, Ralstonia solanacearum; KEGG, K08263. (240 aa)
BAG44587.1COG0277: FAD/FMN-containing dehydrogenases, Ralstonia solanacearum. (1344 aa)
BAG45666.1Hypothetical protein. (131 aa)
gph-5COG0546: Predicted phosphatases, Sinorhizobium meliloti; KEGG, K01091. (224 aa)
gph-6COG0546: Predicted phosphatases, Ralstonia solanacearum; KEGG, K01091. (207 aa)
serA-4COG1052: Lactate dehydrogenase and related dehydrogenases, Ralstonia solanacearum; KEGG, K00058; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (309 aa)
glcB-2Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (724 aa)
BAG47280.1COG0277: FAD/FMN-containing dehydrogenases, Salmonella typhimurium LT2; KEGG, K06911. (1023 aa)
BAG47524.1Predicted membrane protein. (659 aa)
ykgG-2Conserved hypothetical protein; KEGG, K00782. (199 aa)
BAG47526.1COG1139: Uncharacterized conserved protein containing a ferredoxin-like domain, Bacillus halodurans; contains a ferredoxin-like domain. (457 aa)
BAG47527.1COG0247: Fe-S oxidoreductase, Bacillus halodurans. (247 aa)
cydB-3COG1294: Cytochrome bd-type quinol oxidase, subunit 2, Pseudomonas aeruginosa; KEGG, K00426. (325 aa)
cydA-3COG1271: Cytochrome bd-type quinol oxidase, subunit 1, Ralstonia solanacearum; KEGG, K00425. (476 aa)
BAG47544.1LctP family lactate transporter; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (553 aa)
lldD-2COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases, Pseudomonas aeruginosa; KEGG, K00101. (383 aa)
fdh-5Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (386 aa)
Your Current Organism:
Burkholderia multivorans
NCBI taxonomy Id: 395019
Other names: B. multivorans ATCC 17616, Burkholderia multivorans ATCC 17616, Burkholderia multivorans str. ATCC 17616, Burkholderia multivorans strain ATCC 17616
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