STRINGSTRING
fadA-2 fadA-2 atoB-4 atoB-4 atoB-3 atoB-3 BAG47611.1 BAG47611.1 fabI fabI ptb-2 ptb-2 ptb ptb BAG47141.1 BAG47141.1 yhhY yhhY yfiQ yfiQ BAG47065.1 BAG47065.1 BAG47042.1 BAG47042.1 fabV fabV fadA-5 fadA-5 BAG46978.1 BAG46978.1 BAG46898.1 BAG46898.1 BAG46845.1 BAG46845.1 BAG46638.1 BAG46638.1 BAG46461.1 BAG46461.1 BAG46406.1 BAG46406.1 bmuI bmuI nhoA nhoA yncA-2 yncA-2 BAG46225.1 BAG46225.1 BAG46168.1 BAG46168.1 BAG45967.1 BAG45967.1 BAG45959.1 BAG45959.1 pta pta BAG45767.1 BAG45767.1 BAG45764.1 BAG45764.1 BAG45760.1 BAG45760.1 gcp gcp BAG45298.1 BAG45298.1 BAG45203.1 BAG45203.1 cysE-2 cysE-2 kbl kbl BAG44914.1 BAG44914.1 bioF-2 bioF-2 lipB lipB atoB-2 atoB-2 fadA-4 fadA-4 lnt lnt ygiH ygiH BAG44348.1 BAG44348.1 speG-2 speG-2 argA argA pdhC-2 pdhC-2 cysE cysE rimI rimI dapD dapD lpxD lpxD fabZ fabZ lpxA lpxA BAG43863.1 BAG43863.1 BAG43840.1 BAG43840.1 yhbS yhbS fadA-3 fadA-3 BAG43786.1 BAG43786.1 pdhC pdhC atoB atoB dltC dltC BAG43452.1 BAG43452.1 sucB sucB BMULJ_01439 BMULJ_01439 BAG43265.1 BAG43265.1 BAG43224.1 BAG43224.1 BAG43223.1 BAG43223.1 fabD-2 fabD-2 astA-2 astA-2 astA astA elaA elaA yncA yncA fabF fabF fabD fabD fabH fabH plsX plsX BAG42987.1 BAG42987.1 BAG42776.1 BAG42776.1 plsC plsC BAG42601.1 BAG42601.1 bioF bioF argJ argJ fadA fadA glmU glmU metX metX speG speG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fadA-2COG0183: Acetyl-CoA acetyltransferase, Sinorhizobium meliloti; KEGG, K00632; Belongs to the thiolase-like superfamily. Thiolase family. (388 aa)
atoB-4COG0183: Acetyl-CoA acetyltransferase, Brucella melitensis; KEGG, K00626; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
atoB-3COG0183: Acetyl-CoA acetyltransferase, Ralstonia solanacearum; KEGG, K00626; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
BAG47611.1GCN5-related N-acetyltransferase. (142 aa)
fabICOG0623: Enoyl-[acyl-carrier-protein] reductase (NADH), Aquifex aeolicus; KEGG, K00208. (259 aa)
ptb-2Phosphate butyryltransferase; COG0280: Phosphotransacetylase, Rickettsia prowazekii; KEGG, K00634. (313 aa)
ptbPhosphate butyryltransferase; COG0280: Phosphotransacetylase, Rickettsia prowazekii; KEGG, K00634. (343 aa)
BAG47141.1Putative N-acetyltransferase; COG0454: Histone acetyltransferase HPA2 and related acetyltransferases, Ralstonia solanacearum. (168 aa)
yhhYCOG0454: Histone acetyltransferase HPA2 and related acetyltransferases, Salmonella typhimurium LT2; KEGG, K03825. (166 aa)
yfiQConserved hypothetical protein; COG1042: Acyl-CoA synthetase (NDP forming), Mesorhizobium loti; KEGG, K09181. (785 aa)
BAG47065.1Histone acetyltransferase. (159 aa)
BAG47042.1Putative N-acetyltransferase; COG0454: Histone acetyltransferase HPA2 and related acetyltransferases, Pseudomonas aeruginosa. (176 aa)
fabVPutative short-chain alcohol dehydrogenase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (400 aa)
fadA-5COG0183: Acetyl-CoA acetyltransferase, Ralstonia solanacearum; KEGG, K00632; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
BAG46978.1Conserved hypothetical protein. (118 aa)
BAG46898.1GCN5-related N-acetyltransferase. (180 aa)
BAG46845.1COG1020: Non-ribosomal peptide synthetase modules and related proteins, Pseudomonas aeruginosa. (995 aa)
BAG46638.1GCN5-related N-acetyltransferase; COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins, Ralstonia solanacearum. (199 aa)
BAG46461.1Putative N-acetyltransferase; COG0454: Histone acetyltransferase HPA2 and related acetyltransferases, Caulobacter vibrioides. (177 aa)
BAG46406.1Putative GCN5-related N-acetyltransferase. (143 aa)
bmuICOG3916: N-acyl-L-homoserine lactone synthetase, Ralstonia solanacearum. (202 aa)
nhoAN-hydroxyarylamine O-acetyltransferase; COG2162: Arylamine N-acetyltransferase, Mesorhizobium loti; KEGG, K00675; Belongs to the arylamine N-acetyltransferase family. (276 aa)
yncA-2Acetyltransferase; COG1247: Sortase and related acyltransferases, Caulobacter vibrioides; KEGG, K03823. (186 aa)
BAG46225.1GCN5-related N-acetyltransferase; COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins, Saccharomyces cerevisiae. (399 aa)
BAG46168.1Putative N-acetyltransferase; COG0454: Histone acetyltransferase HPA2 and related acetyltransferases, Agrobacterium tumefaciens strain C58. (186 aa)
BAG45967.1ElaA family protein. (194 aa)
BAG45959.1Predicted acyltransferase. (365 aa)
ptaPhosphate acetyltransferase; COG0280: Phosphotransacetylase, Sinorhizobium meliloti; KEGG, K00625. (344 aa)
BAG45767.1COG1835: Predicted acyltransferases, Sinorhizobium meliloti. (372 aa)
BAG45764.1Putative lipopolysaccharide biosynthesis-related membrane protein. (391 aa)
BAG45760.1Acyltransferase family protein. (354 aa)
gcpO-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (346 aa)
BAG45298.1Putative N-acetyltransferase; COG0454: Histone acetyltransferase HPA2 and related acetyltransferases, Yersinia pestis. (167 aa)
BAG45203.1COG3503: Predicted membrane protein, Pseudomonas aeruginosa. (389 aa)
cysE-2Serine O-acetyltransferase; KEGG, K00640. (306 aa)
kblGlycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (399 aa)
BAG44914.1Putative N-acetyltransferase; COG0454: Histone acetyltransferase HPA2 and related acetyltransferases, Ralstonia solanacearum. (215 aa)
bioF-28-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (394 aa)
lipBLipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (248 aa)
atoB-2COG0183: Acetyl-CoA acetyltransferase, Ralstonia solanacearum; KEGG, K00626; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
fadA-4COG0183: Acetyl-CoA acetyltransferase, Ralstonia solanacearum; KEGG, K00632; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
lntApolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (553 aa)
ygiHPutative membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (212 aa)
BAG44348.1COG0456: Acetyltransferases, Yersinia pestis. (151 aa)
speG-2Diamine N-acetyltransferase; COG0454: Histone acetyltransferase HPA2 and related acetyltransferases, Sinorhizobium meliloti; KEGG, K00657. (165 aa)
argAAmino-acid N-acetyltransferase; COG0548: Acetylglutamate kinase, Ralstonia solanacearum; KEGG, K00619; Belongs to the acetyltransferase family. ArgA subfamily. (459 aa)
pdhC-2Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (555 aa)
cysECOG1045: Serine acetyltransferase, Ralstonia solanacearum; KEGG, K00640. (257 aa)
rimIRibosomal-protein-alanine N-acetyltransferase; COG0456: Acetyltransferases, Ralstonia solanacearum; KEGG, K03789. (165 aa)
dapDCOG2171: Tetrahydrodipicolinate N-succinyltransferase, Ralstonia solanacearum; KEGG, K00674. (275 aa)
lpxDUDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (360 aa)
fabZ3R-hydroxymyristoyl ACP dehydrase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (155 aa)
lpxAUDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (262 aa)
BAG43863.1Putative methyl-accepting chemotaxis protein. (133 aa)
BAG43840.1Acetyltransferase. (169 aa)
yhbSCOG3153: Predicted acetyltransferase, Corynebacterium glutamicum; KEGG, K03824. (185 aa)
fadA-3COG0183: Acetyl-CoA acetyltransferase, Ralstonia solanacearum; KEGG, K00632; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
BAG43786.1Putative N-acetyltransferase; COG0454: Histone acetyltransferase HPA2 and related acetyltransferases, Ralstonia solanacearum. (146 aa)
pdhCPyruvate dehydrogenase E2 component; COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily), Pseudomonas aeruginosa; KEGG, K00627. (371 aa)
atoBCOG0183: Acetyl-CoA acetyltransferase, Ralstonia solanacearum; KEGG, K00626; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
dltCD-alanine-poly(phosphoribitol) ligase; COG1020: Non-ribosomal peptide synthetase modules and related proteins, Pseudomonas aeruginosa; KEGG, K03367. (3219 aa)
BAG43452.1GNAT family acetyltransferase. (180 aa)
sucB2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (430 aa)
BMULJ_01439Truncated putative bacteriophage tail protein. (377 aa)
BAG43265.1Surface antigen. (127 aa)
BAG43224.1Putative multi-domain beta keto-acyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (2081 aa)
BAG43223.1Putative acyl transferase. (528 aa)
fabD-2COG0331: (acyl-carrier-protein) S-malonyltransferase, Pseudomonas aeruginosa; KEGG, K00645. (310 aa)
astA-2COG3138: Arginine/ornithine N-succinyltransferase beta subunit, Escherichia coli O157:H7; KEGG, K00673. (348 aa)
astACOG3138: Arginine/ornithine N-succinyltransferase beta subunit, Pseudomonas aeruginosa; KEGG, K00673. (350 aa)
elaAElaA protein; COG2153: Predicted acyltransferase, Pseudomonas aeruginosa; KEGG, K02348. (163 aa)
yncAAcetyltransferase; COG1247: Sortase and related acyltransferases, Ralstonia solanacearum; KEGG, K03823. (184 aa)
fabF3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (410 aa)
fabDCOG0331: (acyl-carrier-protein) S-malonyltransferase, Ralstonia solanacearum; KEGG, K00645. (310 aa)
fabH3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (329 aa)
plsXFatty acid/phospholipid synthesis protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (368 aa)
BAG42987.1Putative N-acetyltransferase; COG0454: Histone acetyltransferase HPA2 and related acetyltransferases, Ralstonia solanacearum. (161 aa)
BAG42776.1Putative acetyltransferase. (170 aa)
plsCCOG0204: 1-acyl-sn-glycerol-3-phosphate acyltransferase, Ralstonia solanacearum; KEGG, K00655. (285 aa)
BAG42601.1COG3321: Polyketide synthase modules and related proteins, Sinorhizobium meliloti. (2543 aa)
bioF8-amino-7-oxononanoate synthase; COG0156: 7-keto-8-aminopelargonate synthetase and related enzymes, Sinorhizobium meliloti; KEGG, K00652. (450 aa)
argJGlutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (413 aa)
fadACOG0183: Acetyl-CoA acetyltransferase, Ralstonia solanacearum; KEGG, K00632; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (453 aa)
metXHomoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. (381 aa)
speGDiamine N-acetyltransferase; COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins, Listeria innocua; KEGG, K00657. (180 aa)
Your Current Organism:
Burkholderia multivorans
NCBI taxonomy Id: 395019
Other names: B. multivorans ATCC 17616, Burkholderia multivorans ATCC 17616, Burkholderia multivorans str. ATCC 17616, Burkholderia multivorans strain ATCC 17616
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