STRINGSTRING
thrB thrB BAG47963.1 BAG47963.1 BAG47938.1 BAG47938.1 BAG47873.1 BAG47873.1 BAG47864.1 BAG47864.1 BAG47848.1 BAG47848.1 rpoN-2 rpoN-2 BAG47822.1 BAG47822.1 BAG47763.1 BAG47763.1 ackA-2 ackA-2 BAG47487.1 BAG47487.1 fruK fruK ackA ackA BAG47450.1 BAG47450.1 BAG47435.1 BAG47435.1 prsA-2 prsA-2 ppsA-2 ppsA-2 BAG47336.1 BAG47336.1 BAG47260.1 BAG47260.1 dak1 dak1 repA4 repA4 BAG47194.1 BAG47194.1 BAG47191.1 BAG47191.1 BAG47176.1 BAG47176.1 BAG47175.1 BAG47175.1 cheR-3 cheR-3 BAG47054.1 BAG47054.1 BAG47033.1 BAG47033.1 selD selD BAG46976.1 BAG46976.1 BAG46900.1 BAG46900.1 otnK otnK BMULJ_04996 BMULJ_04996 coaA coaA BAG46746.1 BAG46746.1 rstB rstB BAG46682.1 BAG46682.1 BAG46674.1 BAG46674.1 BAG46648.1 BAG46648.1 gntK-2 gntK-2 BAG46575.1 BAG46575.1 BAG46259.1 BAG46259.1 BAG46223.1 BAG46223.1 BAG46203.1 BAG46203.1 BAG46164.1 BAG46164.1 xylB-3 xylB-3 BAG46118.1 BAG46118.1 BAG46108.1 BAG46108.1 BAG46054.1 BAG46054.1 cusS-2 cusS-2 tctE tctE baeS baeS dpx dpx manC-2 manC-2 BAG45957.1 BAG45957.1 BAG45952.1 BAG45952.1 BAG45908.1 BAG45908.1 BAG45902.1 BAG45902.1 BAG45901.1 BAG45901.1 cheY-3 cheY-3 BAG45859.1 BAG45859.1 BAG45834.1 BAG45834.1 glpK-2 glpK-2 galU-2 galU-2 BAG45682.1 BAG45682.1 BAG45680.1 BAG45680.1 dnaG dnaG polA polA BAG45555.1 BAG45555.1 BAG45513.1 BAG45513.1 BAG45494.1 BAG45494.1 BAG45487.1 BAG45487.1 BAG45471.1 BAG45471.1 manC manC cheA-2 cheA-2 BAG45373.1 BAG45373.1 BAG45354.1 BAG45354.1 BAG45307.1 BAG45307.1 BAG45292.1 BAG45292.1 hydH hydH BAG45171.1 BAG45171.1 polB polB BAG45065.1 BAG45065.1 nagK nagK cheA cheA fliA fliA BAG44921.1 BAG44921.1 rpoB rpoB rpoC rpoC rpoA rpoA aroK aroK aceK aceK BAG44745.1 BAG44745.1 baf baf dctB dctB pts-Unk-EIIA pts-Unk-EIIA pts-EI-2 pts-EI-2 BAG44668.1 BAG44668.1 dnaE-2 dnaE-2 pts-EI pts-EI pts-Nag-EIIB pts-Nag-EIIB coaD coaD prsA prsA ispE ispE hprK hprK ptsN ptsN rpoN rpoN ubiB ubiB BAG44565.1 BAG44565.1 glpK glpK BAG44502.1 BAG44502.1 pgk pgk pyk pyk sua5-2 sua5-2 BAG44470.1 BAG44470.1 xylB-2 xylB-2 scrK-3 scrK-3 xylB xylB BAG44404.1 BAG44404.1 adk-2 adk-2 kdsB kdsB lpxK-2 lpxK-2 lpxK lpxK ribF ribF cysD cysD cysN cysN holC holC cobV cobV cobP cobP BAG44262.1 BAG44262.1 dnaE dnaE nadD nadD kdpD kdpD dgk-2 dgk-2 pssA pssA pnp pnp acpT acpT glnL glnL dinB dinB bphP bphP lysC lysC dpo dpo thiD-2 thiD-2 glnD glnD pyrH pyrH cds1 cds1 BAG43891.1 BAG43891.1 ppsA ppsA ispD ispD envZ envZ glxK glxK selO selO BAG43792.1 BAG43792.1 tmk tmk holB holB BAG43731.1 BAG43731.1 dnaX dnaX ndk ndk kdgK-2 kdgK-2 kdgK kdgK prkA prkA rbsK rbsK scrK-2 scrK-2 relA-2 relA-2 galU galU BAG43300.1 BAG43300.1 iolC iolC BAG43235.1 BAG43235.1 ppk ppk phoR phoR dnaQ-2 dnaQ-2 citG citG mdcG mdcG pdxK pdxK pgsA pgsA acpS acpS mobA mobA mog mog rfaE rfaE cmk cmk cusS cusS dnaQ dnaQ rpoZ rpoZ gmk gmk BAG42792.1 BAG42792.1 rph rph glk glk livK livK rfe rfe BAG42693.1 BAG42693.1 BAG42692.1 BAG42692.1 thiD thiD rfbA rfbA BAG42591.1 BAG42591.1 pcnB pcnB folK folK dgk dgk nadK nadK glnE glnE anmK anmK gntK gntK holA holA thiL thiL dgoK dgoK adk adk proB proB coaE coaE mraY mraY BAG42278.1 BAG42278.1 scrK scrK glmU glmU cca cca BAG42158.1 BAG42158.1 srkA srkA BAG42119.1 BAG42119.1 argB argB BAG42106.1 BAG42106.1 BAG42091.1 BAG42091.1 dnaN dnaN BAG42022.1 BAG42022.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
thrBCOG2334: Putative homoserine kinase type II (protein kinase fold), Ralstonia solanacearum; KEGG, K02204; Belongs to the pseudomonas-type ThrB family. (332 aa)
BAG47963.1Conserved hypothetical protein. (158 aa)
BAG47938.1COG0642: Signal transduction histidine kinase, Bacillus subtilis. (505 aa)
BAG47873.1COG2334: Putative homoserine kinase type II (protein kinase fold), Mesorhizobium loti. (362 aa)
BAG47864.1Putative signal transduction histidine kinase. (528 aa)
BAG47848.1COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; KEGG, K00936; contains a signal receiver domain. (767 aa)
rpoN-2RNA polymerase sigma54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (475 aa)
BAG47822.1COG1793: ATP-dependent DNA ligase, Agrobacterium tumefaciens strain C58. (927 aa)
BAG47763.1COG0642: Signal transduction histidine kinase, Ralstonia solanacearum. (760 aa)
ackA-2Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (392 aa)
BAG47487.1COG0642: Signal transduction histidine kinase, Pseudomonas aeruginosa; KEGG, K07645. (459 aa)
fruK1-phosphofructokinase; COG1105: Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB), Mycobacterium tuberculosis CDC1551; KEGG, K00882; Belongs to the carbohydrate kinase PfkB family. (311 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (404 aa)
BAG47450.1COG4585: Signal transduction histidine kinase, Ralstonia solanacearum. (671 aa)
BAG47435.1COG2187: Uncharacterized protein conserved in bacteria, Pseudomonas aeruginosa; KEGG, K07028; conserved in bacteria. (536 aa)
prsA-2Ribose-phosphate pyrophosphokinase; COG0462: Phosphoribosylpyrophosphate synthetase, Fusobacterium nucleatum; KEGG, K00948. (335 aa)
ppsA-2Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (803 aa)
BAG47336.1Putative PAS protein. (356 aa)
BAG47260.1COG3395: Uncharacterized protein conserved in bacteria, Sinorhizobium meliloti. (432 aa)
dak1Dihydroxyacetone kinase; Inactivated permease of the major facilitator superfamily. (566 aa)
repA4RepA4 protein. (438 aa)
BAG47194.1COG0642: Signal transduction histidine kinase, Caulobacter vibrioides; contains a signal receiver domain. (758 aa)
BAG47191.1Putative diguanylate cyclase protein; Contains GGDEF domain. (312 aa)
BAG47176.1Two-component system sensor kinase; COG4564: Signal transduction histidine kinase, Ralstonia solanacearum; KEGG, K02480. (459 aa)
BAG47175.1Putative diguanylate cyclase; COG2199: FOG: GGDEF domain, Ralstonia solanacearum; contains GGDEF domain. (522 aa)
cheR-3Chemotaxis protein methyltransferase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (1380 aa)
BAG47054.1Conserved hypothetical protein. (179 aa)
BAG47033.1Aminoglycoside/hydroxyurea antibiotic resistance kinase; COG3570: Streptomycin 6-kinase, Sinorhizobium meliloti. (265 aa)
selDSelenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (357 aa)
BAG46976.1COG4191: Signal transduction histidine kinase regulating C4-dicarboxylate transport system, Ralstonia solanacearum. (627 aa)
BAG46900.1COG0642: Signal transduction histidine kinase, Sinorhizobium meliloti. (442 aa)
otnKConserved hypothetical protein; Catalyzes the ATP-dependent phosphorylation of 3-oxo- tetronate to 3-oxo-tetronate 4-phosphate. (428 aa)
BMULJ_04996Signal transduction histidine kinase; COG5295: Autotransporter adhesin, Mesorhizobium loti; truncated YadA/haemagluttinin like protein. (785 aa)
coaACOG1072: Panthothenate kinase, Sinorhizobium meliloti; KEGG, K00867. (217 aa)
BAG46746.1Putative diguanylate cyclase; COG2199: FOG: GGDEF domain, Yersinia pestis; contains GGDEF domain. (422 aa)
rstBOmpR family two-component system sensor histidine kinase; KEGG, K07639; RstB protein. (376 aa)
BAG46682.1Putative signal transduction histidine kinase; KEGG, K00936. (685 aa)
BAG46674.1COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; KEGG, K00936. (456 aa)
BAG46648.1COG0642: Signal transduction histidine kinase, Pseudomonas aeruginosa. (594 aa)
gntK-2Gluconokinase; COG1070: Sugar (pentulose and hexulose) kinases, Thermotoga maritima; KEGG, K00851. (515 aa)
BAG46575.1COG2068: Uncharacterized MobA-related protein, Ralstonia solanacearum; KEGG, K07141. (194 aa)
BAG46259.1Hypothetical protein. (166 aa)
BAG46223.1COG0642: Signal transduction histidine kinase, Mesorhizobium loti; contains a signal receiver domain. (588 aa)
BAG46203.1Putative diguanylate cyclase; Contains GGDEF domain. (649 aa)
BAG46164.1Putative diguanylate cyclase; COG2199: FOG: GGDEF domain, Caulobacter vibrioides; contains GGDEF domain. (514 aa)
xylB-3Xylulokinase; COG1070: Sugar (pentulose and hexulose) kinases, Salmonella typhimurium LT2; KEGG, K00854. (492 aa)
BAG46118.1COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; contains a signal receiver domain. (654 aa)
BAG46108.1COG4585: Signal transduction histidine kinase, Ralstonia solanacearum. (703 aa)
BAG46054.1COG0840: Methyl-accepting chemotaxis protein, Ralstonia solanacearum. (659 aa)
cusS-2Two-component system heavy metal sensor histidine kinase; Member of a two-component regulatory system. (485 aa)
tctEOmpR family two-component system sensor histidine kinase; COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; KEGG, K07649; TctE protein. (476 aa)
baeSOmpR family two-component system sensor histidine kinase; BaeS protein; COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; KEGG, K07642. (361 aa)
dpxCOG1796: DNA polymerase IV (family X), Methanothermobacter thermautotrophicus; KEGG, K02347. (588 aa)
manC-2COG0836: Mannose-1-phosphate guanylyltransferase, Yersinia pestis; KEGG, K00971; Belongs to the mannose-6-phosphate isomerase type 2 family. (535 aa)
BAG45957.1Protein-tyrosine kinase; COG3206: Uncharacterized protein involved in exopolysaccharide biosynthesis, Ralstonia solanacearum; KEGG, K00903. (761 aa)
BAG45952.1COG2326: Uncharacterized conserved protein, Pseudomonas aeruginosa. (314 aa)
BAG45908.1Putative family X DNA polymerase IV. (292 aa)
BAG45902.1Putative CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (226 aa)
BAG45901.1Putative 2OG-Fe(II) oxygenase. (269 aa)
cheY-3Two-component system response regulator; COG0784: FOG: CheY-like receiver, Pseudomonas aeruginosa; CheY protein; KEGG, K03413. (121 aa)
BAG45859.1Putative signal transduction histidine kinase. (803 aa)
BAG45834.1PleD-related family two-component system response regulator; COG3706: Response regulator containing a CheY-like receiver domain and a GGDEF domain, Pseudomonas aeruginosa; KEGG, K02488. (345 aa)
glpK-2COG0554: Glycerol kinase, Deinococcus radiodurans; KEGG, K00864; Belongs to the FGGY kinase family. (513 aa)
galU-2UTP-glucose-1-phosphate uridylyltransferase; COG1210: UDP-glucose pyrophosphorylase, Ralstonia solanacearum; KEGG, K00963. (295 aa)
BAG45682.1Putative diguanylate cyclase; COG2199: FOG: GGDEF domain, Ralstonia solanacearum; contains GGDEF domain. (492 aa)
BAG45680.1Signal transduction histidine kinase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (1218 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (622 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (917 aa)
BAG45555.1COG3344: Retron-type reverse transcriptase, Nostoc sp. PCC 7120. (339 aa)
BAG45513.1Probable bacteriophage protein. (931 aa)
BAG45494.1COG0642: Signal transduction histidine kinase, Ralstonia solanacearum. (258 aa)
BAG45487.1Conserved hypothetical protein. (233 aa)
BAG45471.1Protein-tyrosine kinase; COG3206: Uncharacterized protein involved in exopolysaccharide biosynthesis, Ralstonia solanacearum; KEGG, K00903. (741 aa)
manCCOG0836: Mannose-1-phosphate guanylyltransferase, Yersinia pestis; KEGG, K00971; Belongs to the mannose-6-phosphate isomerase type 2 family. (508 aa)
cheA-2Two-component system sensor kinase; COG0643: Chemotaxis protein histidine kinase and related kinases, Mesorhizobium loti; CheA protein; KEGG, K03407. (766 aa)
BAG45373.1Putative diguanylate cyclase; COG2199: FOG: GGDEF domain, Ralstonia solanacearum; contains GGDEF domain. (510 aa)
BAG45354.1Putative aminoglycoside phosphotransferase. (396 aa)
BAG45307.1COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; KEGG, K00936. (517 aa)
BAG45292.1COG0642: Signal transduction histidine kinase, Xylella fastidiosa 9a5c. (469 aa)
hydHTwo-component system sensor histidine kinase; COG0642: Signal transduction histidine kinase, Agrobacterium tumefaciens strain C58; HydH protein; KEGG, K07709. (435 aa)
BAG45171.1COG0642: Signal transduction histidine kinase, Mesorhizobium loti. (601 aa)
polBCOG0417: DNA polymerase elongation subunit (family B), Pseudomonas aeruginosa; KEGG, K02336. (791 aa)
BAG45065.1COG0642: Signal transduction histidine kinase, Ralstonia solanacearum. (493 aa)
nagKCOG2971: Predicted N-acetylglucosamine kinase, Mesorhizobium loti; KEGG, K00884. (293 aa)
cheATwo-component system sensor kinase; COG0643: Chemotaxis protein histidine kinase and related kinases, Ralstonia solanacearum; CheA protein; KEGG, K03407. (761 aa)
fliARNA polymerase sigma factor for flagellar operon; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (244 aa)
BAG44921.1COG1881: Phospholipid-binding protein, Salmonella typhimurium LT2; KEGG, K06910. (196 aa)
rpoBDNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1368 aa)
rpoCDNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1413 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (325 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (184 aa)
aceKNADP-dependent isocitrate dehydrogenase kinase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (605 aa)
BAG44745.1Cytidyltransferase-related domain protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (160 aa)
bafPutative transcriptional regulator; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (262 aa)
dctBC4-dicarboxylate transport sensor protein; COG4191: Signal transduction histidine kinase regulating C4-dicarboxylate transport system, Ralstonia solanacearum; DctB protein. (668 aa)
pts-Unk-EIIACOG2893: Phosphotransferase system, mannose/fructose-specific component IIA, Ralstonia solanacearum; KEGG, K02821. (156 aa)
pts-EI-2Phosphotransferase system enzyme I; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (590 aa)
BAG44668.1COG0389: Nucleotidyltransferase/DNA polymerase involved in DNA repair, Ralstonia solanacearum; involved in DNA repair. (495 aa)
dnaE-2DNA polymerase III alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1071 aa)
pts-EICOG1080: Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria), Pseudomonas aeruginosa; KEGG, K02766; Belongs to the PEP-utilizing enzyme family. (860 aa)
pts-Nag-EIIBCOG1263: Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific, Pseudomonas aeruginosa; KEGG, K02803. (596 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (165 aa)
prsARibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (318 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (293 aa)
hprKHPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). (322 aa)
ptsNPTS system nitrogen regulatory IIA component; COG1762: Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type), Ralstonia solanacearum; KEGG, K02806. (151 aa)
rpoNRNA polymerase sigma54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (501 aa)
ubiBUbiquinone biosynthesis protein; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. (525 aa)
BAG44565.1Mannose-1-phosphate guanylyltransferase; COG1208: Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon), Ralstonia solanacearum; KEGG, K00966. (240 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (500 aa)
BAG44502.1OmpR family two-component system sensor histidine kinase; COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; KEGG, K07649. (515 aa)
pgkCOG0126: 3-phosphoglycerate kinase, Ralstonia solanacearum; KEGG, K00927. (398 aa)
pykCOG0469: Pyruvate kinase, Ralstonia solanacearum; KEGG, K00873. (478 aa)
sua5-2Putative translation factor; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (342 aa)
BAG44470.1OmpR family two-component system sensor histidine kinase; COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; KEGG, K07645. (448 aa)
xylB-2Xylulokinase; COG1070: Sugar (pentulose and hexulose) kinases, Sinorhizobium meliloti; KEGG, K00854. (478 aa)
scrK-3Fructokinase; COG0524: Sugar kinases, ribokinase family, Ralstonia solanacearum; KEGG, K00847. (318 aa)
xylBXylulokinase; COG1070: Sugar (pentulose and hexulose) kinases, Ralstonia solanacearum; KEGG, K00854. (493 aa)
BAG44404.1COG2912: Uncharacterized conserved protein, Ralstonia solanacearum. (280 aa)
adk-2Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (220 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (263 aa)
lpxK-2Tetraacyldisaccharide 4'-kinase; COG2835: Uncharacterized conserved protein, Ralstonia solanacearum; KEGG, K00912; Belongs to the UPF0434 family. (64 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (342 aa)
ribFRiboflavin kinase; COG0196: FAD synthase, Ralstonia solanacearum; KEGG, K00861; Belongs to the ribF family. (330 aa)
cysDSulfate adenylyltransferase subunit 2; COG0175: 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes, Ralstonia solanacearum; KEGG, K00957. (320 aa)
cysNSulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (438 aa)
holCCOG2927: DNA polymerase III, chi subunit, Ralstonia solanacearum; KEGG, K02339. (138 aa)
cobVadenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (257 aa)
cobPAdenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (186 aa)
BAG44262.1OmpR family two-component system sensor kinase; COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; KEGG, K02484. (438 aa)
dnaECOG0587: DNA polymerase III, alpha subunit, Ralstonia solanacearum; KEGG, K02337. (1179 aa)
nadDCOG1057: Nicotinic acid mononucleotide adenylyltransferase, Ralstonia solanacearum; KEGG, K00969; Belongs to the NadD family. (196 aa)
kdpDTwo-component system sensor histidine kinase; COG2205: Osmosensitive K+ channel histidine kinase, Ralstonia solanacearum; KEGG, K07646; KdpD protein. (951 aa)
dgk-2Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (178 aa)
pssACOG1183: Phosphatidylserine synthase, Ralstonia solanacearum; KEGG, K00998; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (290 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (715 aa)
acpT4'-phosphopantetheinyl transferase; Frame shift-inactivated ABC amino acid transporter periplasmic ligand-binding protein; Belongs to the P-Pant transferase superfamily. (251 aa)
glnLTwo-component system nitrogen regulation sensor histidine kinase; COG3852: Signal transduction histidine kinase, nitrogen specific, Ralstonia solanacearum; GlnL protein; KEGG, K07708. (380 aa)
dinBDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (388 aa)
bphPPutative signal transduction histidine kinase; COG2202: FOG: PAS/PAC domain, Ralstonia solanacearum; KEGG, K00936; involved in catabolite control. (838 aa)
lysCCOG0527: Aspartokinases, Ralstonia solanacearum; KEGG, K00928; Belongs to the aspartokinase family. (416 aa)
dpoBacteriophage-type DNA polymerase; COG1573: Uracil-DNA glycosylase, Ralstonia solanacearum; KEGG, K02334. (358 aa)
thiD-2COG0351: Hydroxymethylpyrimidine/ phosphomethylpyrimidine kinase, Escherichia coli O157:H7; KEGG, K00941. (269 aa)
glnDCOG2844: UTP:GlnB (protein PII) uridylyltransferase, Ralstonia solanacearum; KEGG, K00990. (858 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (237 aa)
cds1Phosphatidate cytidylyltransferase; COG0575: CDP-diglyceride synthetase, Ralstonia solanacearum; KEGG, K00981; Belongs to the CDS family. (273 aa)
BAG43891.1Conserved hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. (271 aa)
ppsAATP:pyruvate, water phosphotransferase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (799 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (236 aa)
envZTwo-component system osmolarity sensor histidine kinase; COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; EnvZ protein; KEGG, K07638. (453 aa)
glxKCOG1929: Glycerate kinase, Pseudomonas aeruginosa; KEGG, K00865; Belongs to the glycerate kinase type-1 family. (381 aa)
selOConserved hypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). (522 aa)
BAG43792.1Putative diguanylate cyclase; COG2199: FOG: GGDEF domain, Aquifex aeolicus; contains GGDEF domain. (466 aa)
tmkdTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (207 aa)
holBDNA polymerase III delta' subunit; COG0470: ATPase involved in DNA replication, Ralstonia solanacearum; KEGG, K02341. (342 aa)
BAG43731.1ATP-NAD/AcoX kinase; COG3199: Uncharacterized conserved protein, Pseudomonas aeruginosa. (352 aa)
dnaXCOG2812: DNA polymerase III, gamma/tau subunits, Ralstonia solanacearum; KEGG, K02343. (821 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (141 aa)
kdgK-22-dehydro-3-deoxygluconokinase; COG0524: Sugar kinases, ribokinase family, Ralstonia solanacearum; KEGG, K00874. (308 aa)
kdgK2-dehydro-3-deoxygluconokinase; COG0524: Sugar kinases, ribokinase family, Pseudomonas aeruginosa; KEGG, K00874. (328 aa)
prkACOG2766: Putative Ser protein kinase, Pseudomonas aeruginosa; KEGG, K07180. (640 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (310 aa)
scrK-2Fructokinase; COG0524: Sugar kinases, ribokinase family, Ralstonia solanacearum; KEGG, K00847. (319 aa)
relA-2GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (744 aa)
galUUTP-glucose-1-phosphate uridylyltransferase; COG1210: UDP-glucose pyrophosphorylase, Ralstonia solanacearum; KEGG, K00963. (294 aa)
BAG43300.1Periplasmic sensor signal transduction histidine kinase; COG4252: Predicted transmembrane sensor domain, Pseudomonas aeruginosa. (794 aa)
iolC5-dehydro-2-deoxygluconokinase; COG0524: Sugar kinases, ribokinase family, Ralstonia solanacearum; KEGG, K03338. (651 aa)
BAG43235.1Signal transduction GGDEF/EAL domain protein; COG2200: FOG: EAL domain, Pseudomonas aeruginosa. (805 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP); Belongs to the polyphosphate kinase 1 (PPK1) family. (687 aa)
phoROmpR family two-component system phosphate regulon sensor histidine kinase; COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; KEGG, K07636; PhoR protein. (439 aa)
dnaQ-2DNA polymerase III epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (244 aa)
citGtriphosphoribosyl-dephospho-CoA synthase; Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase; Belongs to the CitG/MdcB family. (289 aa)
mdcGphosphoribosyl-dephospho-CoA transferase. (222 aa)
pdxKPyridoxine kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. (286 aa)
pgsACDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; COG0558: Phosphatidylglycerophosphate synthase, Ralstonia solanacearum; KEGG, K00995; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (195 aa)
acpSHolo-[acyl-carrier protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (146 aa)
mobAMolybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (206 aa)
mogCOG0521: Molybdopterin biosynthesis enzymes, Ralstonia solanacearum; KEGG, K03831; Mog protein. (205 aa)
rfaECOG2870: ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase, Ralstonia solanacearum; KEGG, K03272. (316 aa)
cmkCOG0283: Cytidylate kinase, Ralstonia solanacearum; KEGG, K00945. (228 aa)
cusSTwo-component system heavy metal sensor histidine kinase; Member of a two-component regulatory system. (473 aa)
dnaQCOG0847: DNA polymerase III, epsilon subunit and related 3'-5' exonucleases, Neisseria meningitidis Z2491; KEGG, K02342. (375 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (67 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (227 aa)
BAG42792.1Conserved hypothetical protein; COG1561: Uncharacterized stress-induced protein, Ralstonia solanacearum. (307 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (246 aa)
glkCOG0837: Glucokinase, Neisseria meningitidis Z2491; KEGG, K00845; Belongs to the bacterial glucokinase family. (642 aa)
livKCOG0683: ABC-type branched-chain amino acid transport systems, periplasmic component, Ralstonia solanacearum; KEGG, K01999. (435 aa)
rfeUndecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase; COG0472: UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase, Ralstonia solanacearum; KEGG, K02851. (368 aa)
BAG42693.1Putative polysaccharide biosynthesis protein; COG1086: Predicted nucleoside-diphosphate sugar epimerases, Bacillus halodurans. (628 aa)
BAG42692.1Putative phospho-N-acetylmuramoyl-pentapeptide-transferase; COG0472: UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase, Pseudomonas aeruginosa. (338 aa)
thiDCOG0351: Hydroxymethylpyrimidine/ phosphomethylpyrimidine kinase, Pseudomonas aeruginosa; KEGG, K00941. (288 aa)
rfbAGlucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (297 aa)
BAG42591.1ABC-2 type transport system permease protein; COG3524: Capsule polysaccharide export protein, Campylobacter jejuni; KEGG, K01992. (373 aa)
pcnBpoly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (512 aa)
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, Ralstonia solanacearum; KEGG, K00950. (179 aa)
dgkCOG1428: Deoxynucleoside kinases, Ralstonia solanacearum; KEGG, K00904. (228 aa)
nadKNAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (300 aa)
glnEGlutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] (934 aa)
anmKanhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (382 aa)
gntKGluconokinase; COG3265: Gluconate kinase, Ralstonia solanacearum; KEGG, K00851. (167 aa)
holACOG1466: DNA polymerase III, delta subunit, Ralstonia solanacearum; KEGG, K02340. (364 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (332 aa)
dgoK2-dehydro-3-deoxygalactonokinase; COG3734: 2-keto-3-deoxy-galactonokinase, Sinorhizobium meliloti; KEGG, K00883. (341 aa)
adkCOG0524: Sugar kinases, ribokinase family, Ralstonia solanacearum; KEGG, K00856. (298 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (372 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (202 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (389 aa)
BAG42278.1Putative lipoprotein. (210 aa)
scrKFructokinase; COG0524: Sugar kinases, ribokinase family, Deinococcus radiodurans; KEGG, K00847. (302 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (453 aa)
ccatRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. (413 aa)
BAG42158.1Putative signal transduction histidine kinase. (274 aa)
srkAPutative homoserine kinase type II; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. (340 aa)
BAG42119.1COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; KEGG, K00936. (467 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (299 aa)
BAG42106.1COG2326: Uncharacterized conserved protein, Ralstonia solanacearum. (279 aa)
BAG42091.1COG5000: Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation, Ralstonia solanacearum; KEGG, K00936. (800 aa)
dnaNDNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] (368 aa)
BAG42022.1COG0642: Signal transduction histidine kinase, Mesorhizobium loti. (455 aa)
Your Current Organism:
Burkholderia multivorans
NCBI taxonomy Id: 395019
Other names: B. multivorans ATCC 17616, Burkholderia multivorans ATCC 17616, Burkholderia multivorans str. ATCC 17616, Burkholderia multivorans strain ATCC 17616
Server load: low (28%) [HD]