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cobJ cobJ BAG42237.1 BAG42237.1 BAG42308.1 BAG42308.1 hemA hemA BAG42476.1 BAG42476.1 cobO cobO hemH hemH BAG42642.1 BAG42642.1 hemN hemN hemL hemL hemN-2 hemN-2 cobD cobD cobB cobB cobO-2 cobO-2 BAG43578.1 BAG43578.1 cysG cysG chlI chlI chlD chlD cobI cobI cobH cobH cobL cobL cbiD cbiD cobK cobK cobM cobM hemF hemF hemY hemY hemX hemX hemC hemC cobQ cobQ cobP cobP cobD-2 cobD-2 cobC cobC cobV cobV cobU cobU cbiX cbiX cysG-2 cysG-2 cyoE cyoE cox1 cox1 hemB hemB hemE hemE BAG45490.1 BAG45490.1 cobT cobT cysG-3 cysG-3 hemL-2 hemL-2 BAG47173.1 BAG47173.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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cobJCOG1010: Precorrin-3B methylase, Pseudomonas aeruginosa; KEGG, K00594. (571 aa)
BAG42237.1Conserved hypothetical protein. (64 aa)
BAG42308.1COG0500: SAM-dependent methyltransferases, Ralstonia solanacearum. (296 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (432 aa)
BAG42476.1COG1981: Predicted membrane protein, Ralstonia solanacearum; KEGG, K08973. (140 aa)
cobOcob(I)alamin adenosyltransferase; COG2096: Uncharacterized conserved protein, Ralstonia solanacearum; KEGG, K00798; Belongs to the Cob(I)alamin adenosyltransferase family. (183 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (369 aa)
BAG42642.1cob(II)yrinic acid a,c-diamide reductase; COG0778: Nitroreductase, Ralstonia solanacearum; KEGG, K04719. (275 aa)
hemNCOG0635: Coproporphyrinogen III oxidase and related Fe-S oxidoreductases, Ralstonia solanacearum; KEGG, K02495; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (463 aa)
hemLCOG0001: Glutamate-1-semialdehyde aminotransferase, Ralstonia solanacearum; KEGG, K01845. (427 aa)
hemN-2Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (404 aa)
cobDAdenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (312 aa)
cobBHydrogenobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (434 aa)
cobO-2cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (200 aa)
BAG43578.1Cobalamin biosynthesis protein. (125 aa)
cysGuroporphyrin-III C-methyltransferase; COG0007: Uroporphyrinogen-III methylase, Pseudomonas aeruginosa; KEGG, K02302. (254 aa)
chlICOG1239: Mg-chelatase subunit ChlI, Pseudomonas aeruginosa; KEGG, K03405. (360 aa)
chlDCOG1240: Mg-chelatase subunit ChlD, Pseudomonas aeruginosa; KEGG, K03404. (225 aa)
cobIPrecorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. (244 aa)
cobHprecorrin-8X methylmutase; COG2082: Precorrin isomerase, Pseudomonas aeruginosa; KEGG, K01833. (208 aa)
cobLprecorrin-6Y C5,15-methyltransferase; COG2242: Precorrin-6B methylase 2, Pseudomonas aeruginosa; KEGG, K00595. (412 aa)
cbiDCobalamin biosynthesis protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (362 aa)
cobKCOG2099: Precorrin-6x reductase, Pseudomonas aeruginosa; KEGG, K00221. (243 aa)
cobMCOG2875: Precorrin-4 methylase, Pseudomonas aeruginosa; KEGG, K00596. (242 aa)
hemFCoproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (307 aa)
hemYHemY protein; COG3071: Uncharacterized enzyme of heme biosynthesis, Ralstonia solanacearum; KEGG, K02498. (395 aa)
hemXuroporphyrin-III C-methyltransferase; COG1587: Uroporphyrinogen-III synthase, Ralstonia solanacearum; KEGG, K02496. (656 aa)
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (333 aa)
cobQAdenosylcobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (501 aa)
cobPAdenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (186 aa)
cobD-2Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (314 aa)
cobCCobalamin biosynthetic protein; COG0079: Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase, Ralstonia solanacearum; CobC protein; KEGG, K02225. (339 aa)
cobVadenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (257 aa)
cobUNicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (351 aa)
cbiXSirohydrochlorin cobaltochelatase; COG2138: Uncharacterized conserved protein, Ralstonia solanacearum; KEGG, K03795. (126 aa)
cysG-2uroporphyrin-III C-methyltransferase; COG0007: Uroporphyrinogen-III methylase, Ralstonia solanacearum; KEGG, K02302; Belongs to the precorrin methyltransferase family. (252 aa)
cyoEProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (300 aa)
cox1COG1612: Uncharacterized protein required for cytochrome oxidase assembly, Ralstonia solanacearum; KEGG, K02259. (370 aa)
hemBPorphobilinogen synthase; COG0113: Delta-aminolevulinic acid dehydratase, Ralstonia solanacearum; KEGG, K01698; Belongs to the ALAD family. (332 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (364 aa)
BAG45490.1COG0500: SAM-dependent methyltransferases, Agrobacterium tumefaciens strain C58. (234 aa)
cobTCOG4547: Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase), Caulobacter vibrioides; CobT protein; KEGG, K06050. (573 aa)
cysG-3uroporphyrin-III C-methyltransferase; COG0007: Uroporphyrinogen-III methylase, Pseudomonas aeruginosa; KEGG, K02302. (251 aa)
hemL-2COG0001: Glutamate-1-semialdehyde aminotransferase, Pseudomonas aeruginosa; KEGG, K01845; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (452 aa)
BAG47173.1Conserved hypothetical protein; COG3193: Uncharacterized protein, possibly involved in utilization of glycolate and propanediol, Pseudomonas aeruginosa. (134 aa)
Your Current Organism:
Burkholderia multivorans
NCBI taxonomy Id: 395019
Other names: B. multivorans ATCC 17616, Burkholderia multivorans ATCC 17616, Burkholderia multivorans str. ATCC 17616, Burkholderia multivorans strain ATCC 17616
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