STRINGSTRING
phrB phrB argG argG uspA uspA argS argS cysD cysD cysH cysH ribF ribF ileS ileS fixA fixA fixB fixB glnS glnS valS valS BAG43405.1 BAG43405.1 metG metG panC panC BAG44745.1 BAG44745.1 coaD coaD trmU trmU BAG43525.1 BAG43525.1 guaA guaA BAG43936.1 BAG43936.1 gltX gltX mesJ mesJ cysS cysS trpS trpS kdpD kdpD nadD nadD gltX-2 gltX-2 nadE nadE fixA-2 fixA-2 fixB-2 fixB-2 nadE-2 nadE-2 BAG47437.1 BAG47437.1 BAG47451.1 BAG47451.1 BAG47453.1 BAG47453.1 BAG47490.1 BAG47490.1 phrB-2 phrB-2 BAG47501.1 BAG47501.1 BAG47916.1 BAG47916.1 asnB asnB exsB exsB ttcA ttcA leuS leuS tyrS tyrS BAG46353.1 BAG46353.1 BAG46114.1 BAG46114.1 BAG46109.1 BAG46109.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
phrBCOG0415: Deoxyribodipyrimidine photolyase, Mesorhizobium loti; KEGG, K01669; Belongs to the DNA photolyase family. (476 aa)
argGCOG0137: Argininosuccinate synthase, Ralstonia solanacearum; KEGG, K01940; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (445 aa)
uspACOG0589: Universal stress protein UspA and related nucleotide-binding proteins, Ralstonia solanacearum. (158 aa)
argSCOG0018: Arginyl-tRNA synthetase, Ralstonia solanacearum; KEGG, K01887. (598 aa)
cysDSulfate adenylyltransferase subunit 2; COG0175: 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes, Ralstonia solanacearum; KEGG, K00957. (320 aa)
cysHPhosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. (247 aa)
ribFRiboflavin kinase; COG0196: FAD synthase, Ralstonia solanacearum; KEGG, K00861; Belongs to the ribF family. (330 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (945 aa)
fixACOG2086: Electron transfer flavoprotein, beta subunit, Ralstonia solanacearum; KEGG, K03521. (249 aa)
fixBCOG2025: Electron transfer flavoprotein, alpha subunit, Ralstonia solanacearum; KEGG, K03522. (311 aa)
glnSCOG0008: Glutamyl- and glutaminyl-tRNA synthetases, Ralstonia solanacearum; KEGG, K01886. (569 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (955 aa)
BAG43405.1COG1434: Uncharacterized conserved protein, Ralstonia solanacearum; conserved in bacteria. (238 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (722 aa)
panCPantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (279 aa)
BAG44745.1Cytidyltransferase-related domain protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (160 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (165 aa)
trmUtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (381 aa)
BAG43525.1UspA family putative universal stress protein. (165 aa)
guaAGlutamine-hydrolysing GMP synthase; Catalyzes the synthesis of GMP from XMP. (539 aa)
BAG43936.1COG0589: Universal stress protein UspA and related nucleotide-binding proteins, Ralstonia solanacearum. (144 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (469 aa)
mesJCell cycle protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (468 aa)
cysSCOG0215: Cysteinyl-tRNA synthetase, Ralstonia solanacearum; KEGG, K01882; Belongs to the class-I aminoacyl-tRNA synthetase family. (465 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (400 aa)
kdpDTwo-component system sensor histidine kinase; COG2205: Osmosensitive K+ channel histidine kinase, Ralstonia solanacearum; KEGG, K07646; KdpD protein. (951 aa)
nadDCOG1057: Nicotinic acid mononucleotide adenylyltransferase, Ralstonia solanacearum; KEGG, K00969; Belongs to the NadD family. (196 aa)
gltX-2glutamyl-tRNA synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (298 aa)
nadENAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (566 aa)
fixA-2COG2086: Electron transfer flavoprotein, beta subunit, Ralstonia solanacearum; KEGG, K03521. (261 aa)
fixB-2COG2025: Electron transfer flavoprotein, alpha subunit, Ralstonia solanacearum; KEGG, K03522. (389 aa)
nadE-2NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (292 aa)
BAG47437.1COG0589: Universal stress protein UspA and related nucleotide-binding proteins, Ralstonia solanacearum. (157 aa)
BAG47451.1COG0589: Universal stress protein UspA and related nucleotide-binding proteins, Ralstonia solanacearum. (155 aa)
BAG47453.1COG0589: Universal stress protein UspA and related nucleotide-binding proteins, Ralstonia solanacearum. (167 aa)
BAG47490.1Putative universal stress protein UspA. (317 aa)
phrB-2COG0415: Deoxyribodipyrimidine photolyase, Caulobacter vibrioides; KEGG, K01669; Belongs to the DNA photolyase family. (505 aa)
BAG47501.1Conserved hypothetical protein; COG3046: Uncharacterized protein related to deoxyribodipyrimidine photolyase, Vibrio cholerae; KEGG, K06876; related to deoxyribodipyrimidine photolyase. (509 aa)
BAG47916.1COG0589: Universal stress protein UspA and related nucleotide-binding proteins, Ralstonia solanacearum. (162 aa)
asnBCOG0367: Asparagine synthase (glutamine-hydrolyzing), Mesorhizobium loti; KEGG, K01953. (655 aa)
exsBExsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (244 aa)
ttcAPredicted ATPase of the PP-loop superfamily implicated in cell cycle control; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (331 aa)
leuSCOG0495: Leucyl-tRNA synthetase, Ralstonia solanacearum; KEGG, K01869; Belongs to the class-I aminoacyl-tRNA synthetase family. (864 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (413 aa)
BAG46353.1Conserved hypothetical protein. (144 aa)
BAG46114.1UspA family universal stress protein. (312 aa)
BAG46109.1COG0589: Universal stress protein UspA and related nucleotide-binding proteins, Ralstonia solanacearum. (159 aa)
Your Current Organism:
Burkholderia multivorans
NCBI taxonomy Id: 395019
Other names: B. multivorans ATCC 17616, Burkholderia multivorans ATCC 17616, Burkholderia multivorans str. ATCC 17616, Burkholderia multivorans strain ATCC 17616
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