STRINGSTRING
BAG43293.1 BAG43293.1 BAG42179.1 BAG42179.1 glmS glmS glmU glmU scrK scrK BAG42240.1 BAG42240.1 BMULJ_00328 BMULJ_00328 BAG42396.1 BAG42396.1 BAG42630.1 BAG42630.1 galE galE BAG42693.1 BAG42693.1 glmS-2 glmS-2 galE-2 galE-2 manB manB glk glk BAG42905.1 BAG42905.1 BAG42907.1 BAG42907.1 gph-2 gph-2 ugd ugd nagZ nagZ glmM glmM galU galU scrK-2 scrK-2 nanK nanK yfbE yfbE dpm1 dpm1 galE-3 galE-3 BAG43753.1 BAG43753.1 pgi pgi ahpC ahpC comEC comEC ascD ascD murB murB xerD xerD BAG44417.1 BAG44417.1 BAG44513.1 BAG44513.1 BAG44564.1 BAG44564.1 BAG44565.1 BAG44565.1 BAG44592.1 BAG44592.1 BAG44593.1 BAG44593.1 BAG44628.1 BAG44628.1 BAG44643.1 BAG44643.1 pts-Nag-EIIB pts-Nag-EIIB BAG44664.1 BAG44664.1 nagA nagA pts-Unk-EIIA pts-Unk-EIIA murA murA msrQ msrQ nagK nagK BAG45071.1 BAG45071.1 glmS-3 glmS-3 manC manC ugd-2 ugd-2 BAG45544.1 BAG45544.1 BAG45758.1 BAG45758.1 gmd gmd galU-2 galU-2 ahpC-2 ahpC-2 glmS-4 glmS-4 BAG45937.1 BAG45937.1 manC-2 manC-2 murA-2 murA-2 BAG46199.1 BAG46199.1 BAG46299.1 BAG46299.1 rfbB-2 rfbB-2 galE-5 galE-5 ugd-3 ugd-3 BAG46671.1 BAG46671.1 manA manA BAG47107.1 BAG47107.1 dan dan BAG47482.1 BAG47482.1 BAG47551.1 BAG47551.1 BAG47605.1 BAG47605.1 BAG47624.1 BAG47624.1 BAG47656.1 BAG47656.1 rfbB-3 rfbB-3 BAG47908.1 BAG47908.1 BAG47962.1 BAG47962.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
BAG43293.1COG1737: Transcriptional regulators, Ralstonia solanacearum. (294 aa)
BAG42179.1NADH dehydrogenase; COG0702: Predicted nucleoside-diphosphate-sugar epimerases, Ralstonia solanacearum; KEGG, K00329. (319 aa)
glmSGlucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (605 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (453 aa)
scrKFructokinase; COG0524: Sugar kinases, ribokinase family, Deinococcus radiodurans; KEGG, K00847. (302 aa)
BAG42240.1Putative N-acylglucosamine 2-epimerase family protein; COG2942: N-acyl-D-glucosamine 2-epimerase, Xylella fastidiosa 9a5c. (426 aa)
BMULJ_00328Probable peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysins; Inactivated hypothetical protein. (281 aa)
BAG42396.1Tyrosine recombinase. (188 aa)
BAG42630.1Peroxidase; COG0450: Peroxiredoxin, Ralstonia solanacearum; KEGG, K00430. (212 aa)
galEUDP-glucose 4-epimerase; COG0451: Nucleoside-diphosphate-sugar epimerases, Vibrio cholerae; KEGG, K01784. (321 aa)
BAG42693.1Putative polysaccharide biosynthesis protein; COG1086: Predicted nucleoside-diphosphate sugar epimerases, Bacillus halodurans. (628 aa)
glmS-2Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (605 aa)
galE-2COG1087: UDP-glucose 4-epimerase, Ralstonia solanacearum; KEGG, K01784; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (340 aa)
manBCOG1109: Phosphomannomutase, Ralstonia solanacearum; KEGG, K01840. (464 aa)
glkCOG0837: Glucokinase, Neisseria meningitidis Z2491; KEGG, K00845; Belongs to the bacterial glucokinase family. (642 aa)
BAG42905.1Putative integrase/recombinase for integrative and conjugative element; COG0582: Integrase, Sinorhizobium meliloti. (310 aa)
BAG42907.1Tyrosine recombinase; COG0582: Integrase, Sinorhizobium meliloti; Belongs to the 'phage' integrase family. (394 aa)
gph-2COG0546: Predicted phosphatases, Ralstonia solanacearum; KEGG, K01091. (238 aa)
ugdCOG1004: Predicted UDP-glucose 6-dehydrogenase, Ralstonia solanacearum; KEGG, K00012. (466 aa)
nagZbeta-N-acetylhexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (342 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (451 aa)
galUUTP-glucose-1-phosphate uridylyltransferase; COG1210: UDP-glucose pyrophosphorylase, Ralstonia solanacearum; KEGG, K00963. (294 aa)
scrK-2Fructokinase; COG0524: Sugar kinases, ribokinase family, Ralstonia solanacearum; KEGG, K00847. (319 aa)
nanKCOG1940: Transcriptional regulator/sugar kinase, Agrobacterium tumefaciens strain C58; KEGG, K00885. (416 aa)
yfbEPutative lipopolysaccharide biosynthesis protein; COG0399: Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis, Ralstonia solanacearum; KEGG, K07806; Belongs to the DegT/DnrJ/EryC1 family. (383 aa)
dpm1Dolichol-phosphate mannosyltransferase; COG0463: Glycosyltransferases involved in cell wall biogenesis, Ralstonia solanacearum; KEGG, K00721. (341 aa)
galE-3UDP-glucose 4-epimerase; COG0451: Nucleoside-diphosphate-sugar epimerases, Ralstonia solanacearum; KEGG, K01784. (351 aa)
BAG43753.1Polysaccharide deacetylase family protein; COG0726: Predicted xylanase/chitin deacetylase, Ralstonia solanacearum. (298 aa)
pgiCOG0166: Glucose-6-phosphate isomerase, Deinococcus radiodurans; KEGG, K01810; Belongs to the GPI family. (540 aa)
ahpCAlkyl hydroperoxide reductase subunit C; COG0450: Peroxiredoxin, Ralstonia solanacearum; KEGG, K03386. (182 aa)
comECCompetence protein; COG0658: Predicted membrane metal-binding protein, Ralstonia solanacearum; ComEC protein; KEGG, K02238. (824 aa)
ascDCOG0543: 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases, Ralstonia solanacearum; KEGG, K00523. (343 aa)
murBUDP-N-acetylmuramate dehydrogenase; Cell wall formation. (349 aa)
xerDTyrosine recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (316 aa)
BAG44417.1Putative hydrolase; COG0802: Predicted ATPase or kinase, Ralstonia solanacearum; KEGG, K06925. (184 aa)
BAG44513.1COG0662: Mannose-6-phosphate isomerase, Neisseria meningitidis Z2491. (103 aa)
BAG44564.1Conserved hypothetical protein; COG3178: Predicted phosphotransferase related to Ser/Thr protein kinases, Ralstonia solanacearum; KEGG, K07102. (348 aa)
BAG44565.1Mannose-1-phosphate guanylyltransferase; COG1208: Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon), Ralstonia solanacearum; KEGG, K00966. (240 aa)
BAG44592.1COG3653: N-acyl-D-aspartate/D-glutamate deacylase, Ralstonia solanacearum; KEGG, K06015. (493 aa)
BAG44593.1COG1737: Transcriptional regulators, Ralstonia solanacearum. (311 aa)
BAG44628.1Probable ATP-binding protein; Displays ATPase and GTPase activities. (302 aa)
BAG44643.1Tyrosine recombinase. (188 aa)
pts-Nag-EIIBCOG1263: Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific, Pseudomonas aeruginosa; KEGG, K02803. (596 aa)
BAG44664.1COG2222: Predicted phosphosugar isomerases, Pseudomonas aeruginosa; KEGG, K01504. (335 aa)
nagACOG1820: N-acetylglucosamine-6-phosphate deacetylase, Pseudomonas aeruginosa; KEGG, K01443. (367 aa)
pts-Unk-EIIACOG2893: Phosphotransferase system, mannose/fructose-specific component IIA, Ralstonia solanacearum; KEGG, K02821. (156 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (449 aa)
msrQPutative membrane protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, usin [...] (233 aa)
nagKCOG2971: Predicted N-acetylglucosamine kinase, Mesorhizobium loti; KEGG, K00884. (293 aa)
BAG45071.1Tyrosine recombinase; COG0582: Integrase, Ralstonia solanacearum; Belongs to the 'phage' integrase family. (337 aa)
glmS-3Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (609 aa)
manCCOG0836: Mannose-1-phosphate guanylyltransferase, Yersinia pestis; KEGG, K00971; Belongs to the mannose-6-phosphate isomerase type 2 family. (508 aa)
ugd-2COG1004: Predicted UDP-glucose 6-dehydrogenase, Ralstonia solanacearum; KEGG, K00012. (470 aa)
BAG45544.1COG3409: Putative peptidoglycan-binding domain-containing protein, Ralstonia solanacearum. (266 aa)
BAG45758.1NAD-dependent epimerase/dehydratase; COG0451: Nucleoside-diphosphate-sugar epimerases, Xylella fastidiosa 9a5c; KEGG, K01711. (324 aa)
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (347 aa)
galU-2UTP-glucose-1-phosphate uridylyltransferase; COG1210: UDP-glucose pyrophosphorylase, Ralstonia solanacearum; KEGG, K00963. (295 aa)
ahpC-2Alkyl hydroperoxide reductase subunit C; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (187 aa)
glmS-4Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (607 aa)
BAG45937.1COG1737: Transcriptional regulators, Ralstonia solanacearum. (314 aa)
manC-2COG0836: Mannose-1-phosphate guanylyltransferase, Yersinia pestis; KEGG, K00971; Belongs to the mannose-6-phosphate isomerase type 2 family. (535 aa)
murA-2COG0766: UDP-N-acetylglucosamine enolpyruvyl transferase, Borrelia burgdorferi; KEGG, K00790. (433 aa)
BAG46199.1Integrase; Belongs to the 'phage' integrase family. (397 aa)
BAG46299.1Putative RpiR family transcriptional regulator. (291 aa)
rfbB-2dTDP-glucose 4,6-dehydratase; COG0451: Nucleoside-diphosphate-sugar epimerases, Sinorhizobium meliloti; KEGG, K01710. (335 aa)
galE-5COG1087: UDP-glucose 4-epimerase, Sinorhizobium meliloti; KEGG, K01784; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (329 aa)
ugd-3COG1004: Predicted UDP-glucose 6-dehydrogenase, Sinorhizobium meliloti; KEGG, K00012. (471 aa)
BAG46671.1COG1737: Transcriptional regulators, Mesorhizobium loti. (286 aa)
manAMannose-6-phosphate isomerase; COG2942: N-acyl-D-glucosamine 2-epimerase, Ralstonia solanacearum; KEGG, K01809. (369 aa)
BAG47107.1Dihydroflavonol-4-reductase; COG0451: Nucleoside-diphosphate-sugar epimerases, Nostoc sp. PCC 7120; KEGG, K00091. (335 aa)
danCOG3653: N-acyl-D-aspartate/D-glutamate deacylase, Ralstonia solanacearum; KEGG, K06015. (491 aa)
BAG47482.1COG3876: Uncharacterized protein conserved in bacteria, Bacillus subtilis. (785 aa)
BAG47551.1Tyrosine recombinase; Belongs to the 'phage' integrase family. (380 aa)
BAG47605.1Tyrosine recombinase; Belongs to the 'phage' integrase family. (392 aa)
BAG47624.1Tyrosine recombinase. (226 aa)
BAG47656.1Tyrosine recombinase; Belongs to the 'phage' integrase family. (490 aa)
rfbB-3dTDP-glucose 4,6-dehydratase; COG0451: Nucleoside-diphosphate-sugar epimerases, Xylella fastidiosa 9a5c; KEGG, K01710. (348 aa)
BAG47908.1Tyrosine recombinase; COG0582: Integrase, Ralstonia solanacearum; Belongs to the 'phage' integrase family. (575 aa)
BAG47962.1Tyrosine recombinase. (313 aa)
Your Current Organism:
Burkholderia multivorans
NCBI taxonomy Id: 395019
Other names: B. multivorans ATCC 17616, Burkholderia multivorans ATCC 17616, Burkholderia multivorans str. ATCC 17616, Burkholderia multivorans strain ATCC 17616
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