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manC-2 manC-2 BAG42179.1 BAG42179.1 glmU glmU rfbD rfbD rfbC rfbC rfbA rfbA rfbB rfbB galE galE BAG42693.1 BAG42693.1 galE-2 galE-2 ugd ugd galU galU ascD ascD BAG44513.1 BAG44513.1 manC manC ugd-2 ugd-2 BAG45758.1 BAG45758.1 gmd gmd galU-2 galU-2 galE-5 galE-5 ugd-3 ugd-3 BAG47107.1 BAG47107.1 rfbD-2 rfbD-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
manC-2COG0836: Mannose-1-phosphate guanylyltransferase, Yersinia pestis; KEGG, K00971; Belongs to the mannose-6-phosphate isomerase type 2 family. (535 aa)
BAG42179.1NADH dehydrogenase; COG0702: Predicted nucleoside-diphosphate-sugar epimerases, Ralstonia solanacearum; KEGG, K00329. (319 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (453 aa)
rfbDdTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (300 aa)
rfbCdTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (183 aa)
rfbAGlucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (297 aa)
rfbBCOG1088: dTDP-D-glucose 4,6-dehydratase, Ralstonia solanacearum; KEGG, K01710; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (353 aa)
galEUDP-glucose 4-epimerase; COG0451: Nucleoside-diphosphate-sugar epimerases, Vibrio cholerae; KEGG, K01784. (321 aa)
BAG42693.1Putative polysaccharide biosynthesis protein; COG1086: Predicted nucleoside-diphosphate sugar epimerases, Bacillus halodurans. (628 aa)
galE-2COG1087: UDP-glucose 4-epimerase, Ralstonia solanacearum; KEGG, K01784; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (340 aa)
ugdCOG1004: Predicted UDP-glucose 6-dehydrogenase, Ralstonia solanacearum; KEGG, K00012. (466 aa)
galUUTP-glucose-1-phosphate uridylyltransferase; COG1210: UDP-glucose pyrophosphorylase, Ralstonia solanacearum; KEGG, K00963. (294 aa)
ascDCOG0543: 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases, Ralstonia solanacearum; KEGG, K00523. (343 aa)
BAG44513.1COG0662: Mannose-6-phosphate isomerase, Neisseria meningitidis Z2491. (103 aa)
manCCOG0836: Mannose-1-phosphate guanylyltransferase, Yersinia pestis; KEGG, K00971; Belongs to the mannose-6-phosphate isomerase type 2 family. (508 aa)
ugd-2COG1004: Predicted UDP-glucose 6-dehydrogenase, Ralstonia solanacearum; KEGG, K00012. (470 aa)
BAG45758.1NAD-dependent epimerase/dehydratase; COG0451: Nucleoside-diphosphate-sugar epimerases, Xylella fastidiosa 9a5c; KEGG, K01711. (324 aa)
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (347 aa)
galU-2UTP-glucose-1-phosphate uridylyltransferase; COG1210: UDP-glucose pyrophosphorylase, Ralstonia solanacearum; KEGG, K00963. (295 aa)
galE-5COG1087: UDP-glucose 4-epimerase, Sinorhizobium meliloti; KEGG, K01784; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (329 aa)
ugd-3COG1004: Predicted UDP-glucose 6-dehydrogenase, Sinorhizobium meliloti; KEGG, K00012. (471 aa)
BAG47107.1Dihydroflavonol-4-reductase; COG0451: Nucleoside-diphosphate-sugar epimerases, Nostoc sp. PCC 7120; KEGG, K00091. (335 aa)
rfbD-2dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (333 aa)
Your Current Organism:
Burkholderia multivorans
NCBI taxonomy Id: 395019
Other names: B. multivorans ATCC 17616, Burkholderia multivorans ATCC 17616, Burkholderia multivorans str. ATCC 17616, Burkholderia multivorans strain ATCC 17616
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