STRINGSTRING
murG murG murD murD mraY mraY murF murF murE murE ftsI ftsI ddl-2 ddl-2 SEC55666.1 SEC55666.1 SEC58883.1 SEC58883.1 mtgA mtgA SEC70522.1 SEC70522.1 mpl mpl SEC98018.1 SEC98018.1 mrdA mrdA SEC98411.1 SEC98411.1 SED03796.1 SED03796.1 SED06604.1 SED06604.1 murA murA SED10104.1 SED10104.1 SED15506.1 SED15506.1 uppS uppS murB murB SED31037.1 SED31037.1 mrdA-2 mrdA-2 SED45097.1 SED45097.1 uppP uppP SED57517.1 SED57517.1 SED70025.1 SED70025.1 uppP-2 uppP-2 SEC08916.1 SEC08916.1 SEC23557.1 SEC23557.1 ddl ddl murC murC
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
murGUDP-N-acetylglucosamine-N- acetylmuramylpentapeptide N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (356 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (448 aa)
mraYPhospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (360 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (455 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (487 aa)
ftsIPeptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. (580 aa)
ddl-2D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (364 aa)
SEC55666.1Mig-14 protein. (298 aa)
SEC58883.1Penicillin-binding protein 1A. (813 aa)
mtgAMonofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (240 aa)
SEC70522.1N-acetylmuramoyl-L-alanine amidase. (259 aa)
mplUDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. (449 aa)
SEC98018.1Undecaprenyl-diphosphatase. (438 aa)
mrdAPeptidoglycan glycosyltransferase /cell elongation-specific peptidoglycan D,D-transpeptidase; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (631 aa)
SEC98411.1Penicillin-binding protein 6. Serine peptidase. MEROPS family S11; Belongs to the peptidase S11 family. (385 aa)
SED03796.1Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (774 aa)
SED06604.1AmpD protein. (189 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (421 aa)
SED10104.1N-acetyl-anhydromuramyl-L-alanine amidase AmpD. (256 aa)
SED15506.1Membrane carboxypeptidase (penicillin-binding protein). (1039 aa)
uppSUndecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. (251 aa)
murBUDP-N-acetylmuramate dehydrogenase; Cell wall formation. (339 aa)
SED31037.1GNAT-family acetyltransferase TIGR03103. (581 aa)
mrdA-2Peptidoglycan glycosyltransferase /cell elongation-specific peptidoglycan D,D-transpeptidase; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (630 aa)
SED45097.1murein-DD-endopeptidase. Serine peptidase. MEROPS family S11; Belongs to the peptidase S11 family. (312 aa)
uppPUndecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (290 aa)
SED57517.1Undecaprenyl-diphosphatase. (687 aa)
SED70025.1Membrane protein YqaA, SNARE-associated domain. (139 aa)
uppP-2Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (276 aa)
SEC08916.1D-alanyl-D-alanine carboxypeptidase / D-alanyl-D-alanine-endopeptidase (penicillin-binding protein 4). (500 aa)
SEC23557.1Hypothetical protein. (374 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (327 aa)
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (486 aa)
Your Current Organism:
Pseudomonas mohnii
NCBI taxonomy Id: 395600
Other names: Arthrobacter sp. BDR2P2B2-M, CCUG 53115, DSM 18327, P. mohnii, Pseudomonas mohnii Camara et al. 2007, strain IpA-2
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