STRINGSTRING
SEC88730.1 SEC88730.1 SEB58804.1 SEB58804.1 SEB70428.1 SEB70428.1 SEB74412.1 SEB74412.1 SEB90112.1 SEB90112.1 topA topA SEC21722.1 SEC21722.1 SEC22979.1 SEC22979.1 groL groL rhlB rhlB SEC51591.1 SEC51591.1 rnr rnr hfq hfq SEC63813.1 SEC63813.1 SEC75416.1 SEC75416.1 SEC75500.1 SEC75500.1 ppk ppk rho rho SEC83387.1 SEC83387.1 rppH rppH rhlE rhlE SEC91417.1 SEC91417.1 cca cca SEC99707.1 SEC99707.1 SEC99833.1 SEC99833.1 pcnB pcnB dnaK dnaK pnp pnp SED08280.1 SED08280.1 hscA hscA eno eno rnd rnd rne rne SED33652.1 SED33652.1 deaD deaD SED54753.1 SED54753.1 SED59281.1 SED59281.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SEC88730.1ATP-dependent RNA helicase DbpA; Belongs to the DEAD box helicase family. (461 aa)
SEB58804.1Polyphosphate kinase 2, PA0141 family. (273 aa)
SEB70428.1TCP-1/cpn60 chaperonin family protein. (80 aa)
SEB74412.1Cobalamin biosynthesis protein CobW. (355 aa)
SEB90112.1Hypothetical protein. (179 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (875 aa)
SEC21722.1ATP-dependent DNA helicase RecQ. (708 aa)
SEC22979.1Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family. (446 aa)
groLChaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (547 aa)
rhlBATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. (495 aa)
SEC51591.1Hypothetical chaperone protein. (421 aa)
rnrRNAse R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (878 aa)
hfqRNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. (86 aa)
SEC63813.1ATP-dependent DNA helicase, RecQ-like. (652 aa)
SEC75416.1GTPase, G3E family. (401 aa)
SEC75500.1CobW/HypB/UreG, nucleotide-binding domain. (323 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (740 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (419 aa)
SEC83387.1HD domain-containing protein. (213 aa)
rppHPutative (di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. (159 aa)
rhlEATP-dependent RNA helicase RhlE; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. (622 aa)
SEC91417.1comF family protein. (246 aa)
ccatRNA nucleotidyltransferase (CCA-adding enzyme); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. (409 aa)
SEC99707.1Uncharacterized conserved protein, LabA/DUF88 family. (159 aa)
SEC99833.1Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family. (445 aa)
pcnBpoly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (466 aa)
dnaKMolecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (638 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (701 aa)
SED08280.1RNAse G. (485 aa)
hscAChaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. (620 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (429 aa)
rndRibonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. (377 aa)
rneRNAse E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (1063 aa)
SED33652.1polyphosphate:AMP phosphotransferase. (507 aa)
deaDATP-dependent RNA helicase DeaD; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (557 aa)
SED54753.1Polyphosphate kinase 2, PA0141 family. (305 aa)
SED59281.1DNA topoisomerase-3. (649 aa)
Your Current Organism:
Pseudomonas mohnii
NCBI taxonomy Id: 395600
Other names: Arthrobacter sp. BDR2P2B2-M, CCUG 53115, DSM 18327, P. mohnii, Pseudomonas mohnii Camara et al. 2007, strain IpA-2
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.