STRINGSTRING
ACL42938.1 ACL42938.1 ACL43082.1 ACL43082.1 ACL43093.1 ACL43093.1 cofG cofG moaA moaA ACL43292.1 ACL43292.1 moaC moaC thiG thiG ACL44137.1 ACL44137.1 thiE thiE ACL44879.1 ACL44879.1 ACL44966.1 ACL44966.1 thiC thiC cofH cofH ACL45654.1 ACL45654.1 ACL46203.1 ACL46203.1 ACL46590.1 ACL46590.1 ACL46823.1 ACL46823.1 ACL47106.1 ACL47106.1 ACL47310.1 ACL47310.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACL42938.1PFAM: molybdopterin biosynthesis MoaE protein; KEGG: ana:all1638 molybdopterin converting factor, subunit 2. (161 aa)
ACL43082.1PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: npu:Npun_R3296 UBA/ThiF-type NAD/FAD binding protein. (212 aa)
ACL43093.1PFAM: peptidase S16 lon domain protein; KEGG: amr:AM1_1792 ATP-dependent protease La. (216 aa)
cofGRadical SAM domain protein; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. (321 aa)
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (329 aa)
ACL43292.1Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (418 aa)
moaCMolybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (182 aa)
thiGThiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (277 aa)
ACL44137.1PFAM: UBA/THIF-type NAD/FAD binding protein; Rhodanese domain protein; MoeZ/MoeB domain protein; KEGG: tel:tlr2403 molybdopterin biosynthesis protein. (423 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (346 aa)
ACL44879.1TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: ava:Ava_5046 hypothetical protein. (77 aa)
ACL44966.1KEGG: pfo:Pfl01_3049 hypothetical protein. (325 aa)
thiCThiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (458 aa)
cofHRadical SAM domain protein; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. (381 aa)
ACL45654.1TIGRFAM: MoaD family protein; PFAM: thiamineS protein; KEGG: ana:asl4353 molybdenum cofactor biosynthesis protein D. (88 aa)
ACL46203.1Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (187 aa)
ACL46590.1KEGG: cyb:CYB_2833 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. (279 aa)
ACL46823.1Molybdenum cofactor synthesis domain protein; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (174 aa)
ACL47106.1PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: ava:Ava_4256 MoeZ/MoeB. (265 aa)
ACL47310.1PFAM: thiamineS protein; KEGG: amr:AM1_0919 thiamineS protein, putative. (91 aa)
Your Current Organism:
Cyanothece sp. PCC7425
NCBI taxonomy Id: 395961
Other names: C. sp. PCC 7425, Cyanothece sp. ATCC 29141, Cyanothece sp. PCC 7425, Synechococcus sp. PCC 7425
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