STRINGSTRING
cbiD cbiD ACL42747.1 ACL42747.1 cobD cobD ACL42870.1 ACL42870.1 ACL43077.1 ACL43077.1 ACL43185.1 ACL43185.1 ACL43356.1 ACL43356.1 ACL43418.1 ACL43418.1 ACL43459.1 ACL43459.1 ACL43577.1 ACL43577.1 ACL43659.1 ACL43659.1 ACL43663.1 ACL43663.1 ACL43664.1 ACL43664.1 ACL43908.1 ACL43908.1 ACL43971.1 ACL43971.1 ACL44033.1 ACL44033.1 ACL44044.1 ACL44044.1 ACL44254.1 ACL44254.1 hemF hemF ACL44363.1 ACL44363.1 ACL44484.1 ACL44484.1 ACL44615.1 ACL44615.1 ACL44658.1 ACL44658.1 ACL44659.1 ACL44659.1 ACL44987.1 ACL44987.1 cobQ cobQ ACL45243.1 ACL45243.1 ACL45302.1 ACL45302.1 cbiA cbiA ACL45649.1 ACL45649.1 cobS cobS hemA hemA ACL45879.1 ACL45879.1 ACL45880.1 ACL45880.1 chlB chlB ACL46111.1 ACL46111.1 ACL46162.1 ACL46162.1 chlL chlL chlN chlN ACL46586.1 ACL46586.1 ACL46587.1 ACL46587.1 ACL46638.1 ACL46638.1 acsF acsF hemL hemL hemE hemE ACL46733.1 ACL46733.1 hemH hemH ACL46881.1 ACL46881.1 ACL46927.1 ACL46927.1 ACL47083.1 ACL47083.1 ACL47084.1 ACL47084.1 ACL47085.1 ACL47085.1 acsF-2 acsF-2 ACL47121.1 ACL47121.1 ACL47147.1 ACL47147.1 pcyA pcyA hemC hemC ACL47279.1 ACL47279.1 ACL47387.1 ACL47387.1 ACL47427.1 ACL47427.1 ACL47535.1 ACL47535.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
cbiDCobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (379 aa)
ACL42747.1PFAM: PUCC protein; major facilitator superfamily MFS_1; KEGG: tel:tlr0140 similar to light-harvesting 1 (B870) complex assembly protein PucC. (488 aa)
cobDCobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (332 aa)
ACL42870.1PFAM: conserved hypothetical protein; KEGG: ava:Ava_2765 hypothetical protein. (195 aa)
ACL43077.1PFAM: cobalbumin biosynthesis protein; KEGG: ava:Ava_3872 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase. (193 aa)
ACL43185.1Magnesium chelatase ATPase subunit D; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. (664 aa)
ACL43356.1Magnesium chelatase ATPase subunit I; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. (369 aa)
ACL43418.1KEGG: cyt:cce_0538 precorrin-2 C20-methyltransferase; TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. (245 aa)
ACL43459.1Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: ava:Ava_3297 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (327 aa)
ACL43577.1PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: amr:AM1_2009 sirohydrochlorin cobaltochelatase (CbiX). (365 aa)
ACL43659.1PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: syp:SYNPCC7002_A0528 precorrin isomerase (precorrin-8X methylmutase). (205 aa)
ACL43663.1KEGG: amr:AM1_3665 precorrin-6y C5,15-methyltransferase; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. (428 aa)
ACL43664.1PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: cyt:cce_3969 precorrin-8X methylmutase. (203 aa)
ACL43908.1PFAM: Phosphoglycerate mutase; KEGG: gvi:glr0999 hypothetical protein. (213 aa)
ACL43971.1KEGG: npu:Npun_R1575 magnesium protoporphyrin O-methyltransferase; TIGRFAM: magnesium protoporphyrin O-methyltransferase; PFAM: Magnesium-protoporphyrin IX methyltransferase domain protein; Methyltransferase type 11; Methyltransferase type 12. (253 aa)
ACL44033.1TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase FAD-binding; KEGG: syp:SYNPCC7002_A2476 geranylgeranyl reductase. (407 aa)
ACL44044.1TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: amr:AM1_4688 bifunctional CbiG protein and precorrin-3B C17-methyltransferase. (629 aa)
ACL44254.1TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: amr:AM1_4582 precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. (262 aa)
hemFCoproporphyrinogen oxidase; Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. (345 aa)
ACL44363.1Light-dependent protochlorophyllide reductase; Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide). (320 aa)
ACL44484.1PFAM: UbiA prenyltransferase; KEGG: amr:AM1_D0196 UbiA family prenyltransferase. (294 aa)
ACL44615.1PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; KEGG: npu:Npun_R5367 coenzyme F420 hydrogenase/dehydrogenase beta subunit. (402 aa)
ACL44658.1TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; Lycopene beta and epsilon cyclase; KEGG: amr:AM1_5508 geranylgeranyl reductase family protein. (374 aa)
ACL44659.1PFAM: NHL repeat containing protein; KEGG: rha:RHA1_ro00505 serine/threonine-protein kinase. (295 aa)
ACL44987.1Magnesium chelatase, H subunit; KEGG: ava:Ava_1940 hydrogenobyrinic acid a,c-diamide cobaltochelatase; TIGRFAM: magnesium chelatase, H subunit; PFAM: CobN/magnesium chelatase. (1233 aa)
cobQCobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (502 aa)
ACL45243.1Cobaltochelatase, CobN subunit; KEGG: ter:Tery_0132 cobaltochelatase; TIGRFAM: cobaltochelatase, CobN subunit; PFAM: CobN/magnesium chelatase. (1348 aa)
ACL45302.1PFAM: Haem oxygenase-like; KEGG: tel:tll0365 heme oxygenase 1. (239 aa)
cbiACobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (462 aa)
ACL45649.1PFAM: Ferritin Dps family protein; KEGG: mar:MAE_28690 bacterioferritin. (148 aa)
cobSCobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (256 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (432 aa)
ACL45879.1PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: ava:Ava_2921 cobalamin (vitamin B12) biosynthesis CbiX protein. (250 aa)
ACL45880.1TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mar:MAE_47270 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (261 aa)
chlBLight-independent protochlorophyllide reductase, B subunit; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (ChlN-ChlB) is the catalytic component of the complex. (507 aa)
ACL46111.1PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; KEGG: amr:AM1_0830 hypothetical protein. (377 aa)
ACL46162.1Chlorophyll synthase, ChlG; TIGRFAM: bacteriochlorophyll/chlorophyll synthetase; chlorophyll synthase, ChlG; PFAM: UbiA prenyltransferase; KEGG: ana:all4480 chlorophyll synthase 33 kD subunit. (340 aa)
chlLLight-independent protochlorophyllide reductase, iron-sulfur ATP-binding protein; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP. (286 aa)
chlNLight-independent protochlorophyllide reductase, N subunit; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (ChlN-ChlB) is the catalytic component of the complex. (468 aa)
ACL46586.1TIGRFAM: C-3',4' desaturase CrtD; PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: npu:Npun_R2959 phytoene dehydrogenase-related protein. (499 aa)
ACL46587.1KEGG: ana:alr2783 unknown protein. (279 aa)
ACL46638.1TIGRFAM: cobalamin biosynthesis protein CobW; PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: ana:all3392 cobalamin synthesis protein. (358 aa)
acsFMagnesium-protoporphyrin IX monomethyl ester aerobic oxidative cyclase; Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME); Belongs to the AcsF family. (358 aa)
hemLTIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: amr:AM1_0549 glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (432 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (349 aa)
ACL46733.1PFAM: Phosphoglycerate mutase; KEGG: amr:AM1_1138 phosphoglycerate mutase, putative. (222 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (387 aa)
ACL46881.1PFAM: nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; KEGG: ana:alr0607 ferredoxin--nitrite reductase. (521 aa)
ACL46927.1PFAM: ferrochelatase; KEGG: ter:Tery_0602 ferrochelatase; Belongs to the ferrochelatase family. (403 aa)
ACL47083.1Response regulator receiver protein; KEGG: rrs:RoseRS_0942 magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase; TIGRFAM: magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase; PFAM: response regulator receiver; cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (675 aa)
ACL47084.1KEGG: ava:Ava_4393 coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (465 aa)
ACL47085.1PFAM: Haem oxygenase-like; KEGG: syn:sll1875 heme oxygenase. (251 aa)
acsF-2Magnesium-protoporphyrin IX monomethyl ester aerobic oxidative cyclase; Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME); Belongs to the AcsF family. (355 aa)
ACL47121.1cob(I)alamin adenosyltransferase; KEGG: syf:Synpcc7942_0957 cob(I)yrinic acid a,c-diamide adenosyltransferase; TIGRFAM: cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. (216 aa)
ACL47147.1TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: npu:Npun_R1866 uroporphyrin-III C-methyltransferase. (520 aa)
pcyAFerredoxin-dependent bilin reductase; Catalyzes the four-electron reduction of biliverdin IX-alpha (2-electron reduction at both the A and D rings); the reaction proceeds via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin. Belongs to the HY2 family. (259 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (322 aa)
ACL47279.1KEGG: tel:tlr0271 magnesium protoporphyrin IX chelatase subunit H; TIGRFAM: magnesium chelatase, H subunit; PFAM: CobN/magnesium chelatase. (1330 aa)
ACL47387.1KEGG: npu:Npun_F2523 cob(I)alamin adenosyltransferase. (178 aa)
ACL47427.1TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: amr:AM1_2859 cobalt-precorrin-6x reductase. (254 aa)
ACL47535.1TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; KEGG: ava:Ava_1817 precorrin-6B methylase. (200 aa)
Your Current Organism:
Cyanothece sp. PCC7425
NCBI taxonomy Id: 395961
Other names: C. sp. PCC 7425, Cyanothece sp. ATCC 29141, Cyanothece sp. PCC 7425, Synechococcus sp. PCC 7425
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