STRINGSTRING
ACL42696.1 ACL42696.1 ACL42697.1 ACL42697.1 ACL42921.1 ACL42921.1 ACL42922.1 ACL42922.1 ACL42923.1 ACL42923.1 ACL42924.1 ACL42924.1 ACL43120.1 ACL43120.1 clpP clpP clpP-2 clpP-2 ACL43890.1 ACL43890.1 ACL43891.1 ACL43891.1 ACL44074.1 ACL44074.1 ACL44075.1 ACL44075.1 ACL44212.1 ACL44212.1 ftsH ftsH ACL44370.1 ACL44370.1 ACL44483.1 ACL44483.1 groL groL ACL44801.1 ACL44801.1 ACL44802.1 ACL44802.1 ACL45064.1 ACL45064.1 ACL45300.1 ACL45300.1 ACL45305.1 ACL45305.1 clpB clpB ftsH-2 ftsH-2 ACL46165.1 ACL46165.1 ACL46218.1 ACL46218.1 ACL46415.1 ACL46415.1 ACL46416.1 ACL46416.1 ACL46417.1 ACL46417.1 ACL46418.1 ACL46418.1 ACL46419.1 ACL46419.1 dnaK dnaK ACL46442.1 ACL46442.1 ACL46499.1 ACL46499.1 dnaK-2 dnaK-2 ACL46555.1 ACL46555.1 ftsH-3 ftsH-3 clpP-3 clpP-3 clpX clpX clpB-2 clpB-2 ACL46907.1 ACL46907.1 dnaJ dnaJ dnaK-3 dnaK-3 grpE grpE ACL47009.1 ACL47009.1 hrcA hrcA groL-2 groL-2 groS groS ACL47457.1 ACL47457.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACL42696.1PFAM: glutaredoxin; KEGG: amr:AM1_3463 membrane associated glutaredoxin, putative. (278 aa)
ACL42697.1Transcriptional regulator, MerR family; PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: cyt:cce_1699 MerR family transcriptional regulator. (154 aa)
ACL42921.1PFAM: protein of unknown function UPF0027; KEGG: amr:AM1_4754 hypothetical protein. (393 aa)
ACL42922.1PFAM: band 7 protein; KEGG: tel:tlr2184 hypothetical protein. (317 aa)
ACL42923.1PFAM: protein of unknown function DUF107; KEGG: amr:AM1_3972 hypothetical protein. (167 aa)
ACL42924.1PFAM: cyclic nucleotide-binding; MscS Mechanosensitive ion channel; KEGG: tel:tlr1736 hypothetical protein. (472 aa)
ACL43120.1PFAM: heat shock protein DnaJ domain protein; KEGG: ter:Tery_1240 heat shock protein DnaJ-like. (232 aa)
clpPEndopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (218 aa)
clpP-2Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (198 aa)
ACL43890.1PFAM: heat shock protein DnaJ domain protein; KEGG: amr:AM1_0181 DnaJ-like protein, putative. (228 aa)
ACL43891.1PFAM: AIG2 family protein; KEGG: tel:tlr1143 hypothetical protein. (134 aa)
ACL44074.1KEGG: cya:CYA_0855 hypothetical protein. (330 aa)
ACL44075.1PFAM: heat shock protein DnaJ domain protein; KEGG: mar:MAE_24530 heat shock protein DnaJ-like. (188 aa)
ACL44212.1PFAM: band 7 protein; KEGG: npu:Npun_F2648 band 7 protein. (280 aa)
ftsHATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (612 aa)
ACL44370.1ATP-binding region ATPase domain protein; Molecular chaperone. Has ATPase activity. (656 aa)
ACL44483.1PFAM: heat shock protein Hsp20; KEGG: npu:Npun_F0198 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. (180 aa)
groLChaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (553 aa)
ACL44801.1PFAM: Heat shock protein 70; KEGG: cya:CYA_0343 DnaK family protein. (520 aa)
ACL44802.1KEGG: cyb:CYB_1504 hypothetical protein. (213 aa)
ACL45064.1Transcriptional regulator, MerR family; PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: syp:SYNPCC7002_A0131 MerR family transcriptional regulator. (150 aa)
ACL45300.1PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: amr:AM1_1111 heat shock protein DnaJ. (340 aa)
ACL45305.1Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; Clp domain protein; KEGG: amr:AM1_6307 transcriptional regulator with ATPase activity. (224 aa)
clpBATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (872 aa)
ftsH-2ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (631 aa)
ACL46165.1PFAM: Heat shock protein 70; KEGG: amr:AM1_2057 DnaK family protein. (532 aa)
ACL46218.1PFAM: TPR repeat-containing protein; heat shock protein DnaJ domain protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: amr:AM1_3990 DnaJ-like protein, putative. (341 aa)
ACL46415.1PFAM: protein of unknown function DUF323; KEGG: npu:Npun_R3273 hypothetical protein. (358 aa)
ACL46416.1PFAM: Heat shock protein 70; KEGG: cya:CYA_0343 DnaK family protein. (520 aa)
ACL46417.1KEGG: cyb:CYB_1504 hypothetical protein. (250 aa)
ACL46418.1KEGG: cyb:CYB_1805 hypothetical protein. (71 aa)
ACL46419.1PFAM: leucine rich repeat variant; KEGG: dge:Dgeo_0869 leucine-rich repeat-containing protein. (759 aa)
dnaKChaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (630 aa)
ACL46442.1PFAM: heat shock protein Hsp20; KEGG: npu:Npun_F1627 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. (154 aa)
ACL46499.1PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: amr:AM1_5693 DnaJ-like protein. (333 aa)
dnaK-2Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (691 aa)
ACL46555.1PFAM: ATP-dependent Clp protease adaptor protein ClpS; KEGG: mes:Meso_2130 ATP-dependent Clp protease adaptor; Belongs to the ClpS family. (234 aa)
ftsH-3ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (632 aa)
clpP-3ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (236 aa)
clpXATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (447 aa)
clpB-2ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (899 aa)
ACL46907.1PFAM: band 7 protein; KEGG: pab:PAB1933 stomatin-like protein. (315 aa)
dnaJChaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (374 aa)
dnaK-3Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (643 aa)
grpEGrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] (246 aa)
ACL47009.1PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: tel:tll0307 ATP-dependent Clp protease regulatory subunit; Belongs to the ClpA/ClpB family. (825 aa)
hrcAHeat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. (364 aa)
groL-2Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (545 aa)
groSChaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (103 aa)
ACL47457.1PFAM: band 7 protein; KEGG: ote:Oter_1052 band 7 protein. (298 aa)
Your Current Organism:
Cyanothece sp. PCC7425
NCBI taxonomy Id: 395961
Other names: C. sp. PCC 7425, Cyanothece sp. ATCC 29141, Cyanothece sp. PCC 7425, Synechococcus sp. PCC 7425
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