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| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (204 aa) |
| | ACL42770.1 | PFAM: SMC domain protein; KEGG: mar:MAE_39710 ATPase. (430 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (325 aa) |
| | ACL43299.1 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: npu:Npun_AF183 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein. (445 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form th [...] (381 aa) |
| | ACL43343.1 | PFAM: Creatininase; KEGG: amr:AM1_3305 creatininase. (259 aa) |
| | ACL43348.1 | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mms:mma_1841 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein. (156 aa) |
| | ACL43356.1 | Magnesium chelatase ATPase subunit I; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. (369 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (293 aa) |
| | pdhA | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (342 aa) |
| | tmk | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (234 aa) |
| | ACL43379.1 | KEGG: npu:Npun_F6434 DNA polymerase III, delta prime subunit. (325 aa) |
| | ACL43418.1 | KEGG: cyt:cce_0538 precorrin-2 C20-methyltransferase; TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. (245 aa) |
| | ACL43429.1 | KEGG: cyt:cce_3678 hypothetical protein. (121 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (352 aa) |
| | ACL43459.1 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: ava:Ava_3297 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (327 aa) |
| | ACL43467.1 | PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: amr:AM1_5801 CobW/P47K domain-containing protein. (384 aa) |
| | moaC | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (182 aa) |
| | ACL43577.1 | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: amr:AM1_2009 sirohydrochlorin cobaltochelatase (CbiX). (365 aa) |
| | ctaB | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (324 aa) |
| | ACL43589.1 | PFAM: cytochrome oxidase assembly; KEGG: npu:Npun_R5530 cytochrome oxidase assembly. (336 aa) |
| | pdxH | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (213 aa) |
| | ACL43659.1 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: syp:SYNPCC7002_A0528 precorrin isomerase (precorrin-8X methylmutase). (205 aa) |
| | ACL43663.1 | KEGG: amr:AM1_3665 precorrin-6y C5,15-methyltransferase; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. (428 aa) |
| | ACL43664.1 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: cyt:cce_3969 precorrin-8X methylmutase. (203 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (195 aa) |
| | rpoA | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (314 aa) |
| | ACL43712.1 | PFAM: Radical SAM domain protein; KEGG: amr:AM1_5084 radical SAM domain-containing protein. (337 aa) |
| | rpoZ | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (75 aa) |
| | bioD | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (226 aa) |
| | ACL43748.1 | PFAM: adenosine/AMP deaminase; KEGG: cyt:cce_4185 putative adenosine/AMP deaminase. (341 aa) |
| | ACL43758.1 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (400 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (549 aa) |
| | ACL43807.1 | KEGG: gvi:gll1166 hypothetical protein. (182 aa) |
| | purH | KEGG: npu:Npun_R6316 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. (514 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (267 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (257 aa) |
| | ACL43850.1 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa) |
| | atpB | ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (257 aa) |
| | atpE | ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (82 aa) |
| | atpG | H+transporting two-sector ATPase B/B' subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria. Belongs to the ATPase B chain family. (138 aa) |
| | atpF | H+transporting two-sector ATPase B/B' subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (181 aa) |
| | atpH | ATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (185 aa) |
| | atpA | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (505 aa) |
| | atpG-2 | ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (315 aa) |
| | ACL43879.1 | TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; KEGG: npu:Npun_F6048 dihydroorotase, multifunctional complex type. (414 aa) |
| | sigA | RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (378 aa) |
| | ACL43886.1 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (405 aa) |
| | nadK | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (308 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (388 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (92 aa) |
| | ACL43932.1 | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: ter:Tery_3993 adenylate/guanylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (435 aa) |
| | ACL43954.1 | RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (327 aa) |
| | ACL43968.1 | PFAM: Glycosyl transferase, family 3-like; KEGG: npu:Npun_F1535 glycosyl transferase family protein. (351 aa) |
| | ACL43971.1 | KEGG: npu:Npun_R1575 magnesium protoporphyrin O-methyltransferase; TIGRFAM: magnesium protoporphyrin O-methyltransferase; PFAM: Magnesium-protoporphyrin IX methyltransferase domain protein; Methyltransferase type 11; Methyltransferase type 12. (253 aa) |
| | queG | Iron-sulfur cluster binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (312 aa) |
| | thiG | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (277 aa) |
| | ACL44010.1 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: amr:AM1_3600 RNA polymerase sigma factor RpoE; Belongs to the sigma-70 factor family. ECF subfamily. (221 aa) |
| | ACL44031.1 | KEGG: ava:Ava_0120 dihydroorotase; TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase. (469 aa) |
| | ACL44033.1 | TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase FAD-binding; KEGG: syp:SYNPCC7002_A2476 geranylgeranyl reductase. (407 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (367 aa) |
| | carB | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: tel:tll2332 carbamoyl-phosphate synthase pyrimidine-specific large chain; Belongs to the CarB family. (1107 aa) |
| | ACL44042.1 | RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (318 aa) |
| | ACL44044.1 | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: amr:AM1_4688 bifunctional CbiG protein and precorrin-3B C17-methyltransferase. (629 aa) |
| | ACL44045.1 | TIGRFAM: competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; CinA domain protein; KEGG: tel:tlr2129 putative competence-damage protein; Belongs to the CinA family. (418 aa) |
| | ACL44053.1 | KEGG: syp:SYNPCC7002_A0163 hypothetical protein. (230 aa) |
| | ACL44055.1 | RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: amr:AM1_4757 RNA polymerase sigma factor SigF. (263 aa) |
| | ACL44118.1 | PFAM: GCN5-related N-acetyltransferase; KEGG: ana:all0118 hypothetical protein. (167 aa) |
| | queA | S-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (381 aa) |
| | purD | KEGG: ava:Ava_3227 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. (433 aa) |
| | ACL44155.1 | RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (455 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (170 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (690 aa) |
| | ACL44254.1 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: amr:AM1_4582 precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. (262 aa) |
| | ACL42734.1 | PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; KEGG: ana:alr0297 hypothetical protein; Belongs to the UPF0284 family. (368 aa) |
| | cbiD | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (379 aa) |
| | guaA | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (537 aa) |
| | ACL42682.1 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (1272 aa) |
| | ACL42672.1 | KEGG: ana:all3132 ABC transport protein, ATP-binding subunit. (382 aa) |
| | ACL42641.1 | PFAM: Proto-chlorophyllide reductase 57 kD subunit; KEGG: amr:AM1_1085 hypothetical protein. (61 aa) |
| | ACL42632.1 | KEGG: npu:Npun_F4648 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. (167 aa) |
| | queF | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (142 aa) |
| | fcl | NAD-dependent epimerase/dehydratase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (314 aa) |
| | ACL42595.1 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (374 aa) |
| | hemF | Coproporphyrinogen oxidase; Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. (345 aa) |
| | ACL44276.1 | PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: npu:Npun_R3841 cobalamin synthesis protein, P47K. (323 aa) |
| | carA | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: ava:Ava_4410 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. (389 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (245 aa) |
| | ACL44363.1 | Light-dependent protochlorophyllide reductase; Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide). (320 aa) |
| | ACL44401.1 | PFAM: transcriptional coactivator/pterin dehydratase; KEGG: ana:asr4549 pterin-4a-carbinolamine dehydratase. (97 aa) |
| | ACL44408.1 | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (208 aa) |
| | ACL44439.1 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (285 aa) |
| | nusA | NusA antitermination factor; Participates in both transcription termination and antitermination. (413 aa) |
| | ACL44459.1 | PFAM: protein of unknown function DUF927; KEGG: seh:SeHA_C2642 zinc-binding domain of primase-helicase family. (1051 aa) |
| | ACL44490.1 | KEGG: ana:alr4529 hypothetical protein. (215 aa) |
| | ACL44510.1 | KEGG: sez:Sez_0212 abortive phage resistance protein. (196 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (408 aa) |
| | ACL44597.1 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (465 aa) |
| | ACL44598.1 | TIGRFAM: cytidyltransferase-related domain protein; PFAM: cytidylyltransferase; KEGG: amr:AM1_4897 nicotinate (nicotinamide) nucleotide adenylyltransferase; Belongs to the NadD family. (172 aa) |
| | nadE | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (558 aa) |
| | ACL44680.1 | KEGG: ava:Ava_0670 hypothetical protein. (146 aa) |
| | ACL44732.1 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (558 aa) |
| | ACL44733.1 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (559 aa) |
| | ACL44735.1 | PFAM: Forkhead-associated protein; adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: tel:tll2410 adenylate cyclase. (395 aa) |
| | ACL44741.1 | KEGG: npu:Npun_F0942 beta-lactamase domain-containing protein. (320 aa) |
| | ACL44742.1 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: amr:AM1_2652 riboflavin biosynthesis protein RibF; Belongs to the ribF family. (311 aa) |
| | ACL44786.1 | KEGG: amr:AM1_2681 hypothetical protein. (499 aa) |
| | ACL44789.1 | PFAM: VWA containing CoxE family protein; SMART: von Willebrand factor type A; KEGG: amr:AM1_3312 hypothetical protein. (403 aa) |
| | glmU | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (453 aa) |
| | ACL44852.1 | KEGG: amr:AM1_4618 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. (292 aa) |
| | thiE | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (346 aa) |
| | ACL44879.1 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: ava:Ava_5046 hypothetical protein. (77 aa) |
| | purA | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (445 aa) |
| | ribBA | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (580 aa) |
| | ACL44910.1 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (292 aa) |
| | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (447 aa) |
| | ribH | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (200 aa) |
| | ACL44947.1 | KEGG: npu:Npun_BF100 hypothetical protein. (173 aa) |
| | ACL44950.1 | PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; KEGG: amr:AM1_4350 circadian phase modifier CpmA. (258 aa) |
| | ACL44986.1 | KEGG: npu:Npun_F0315 hypothetical protein. (126 aa) |
| | ACL44987.1 | Magnesium chelatase, H subunit; KEGG: ava:Ava_1940 hydrogenobyrinic acid a,c-diamide cobaltochelatase; TIGRFAM: magnesium chelatase, H subunit; PFAM: CobN/magnesium chelatase. (1233 aa) |
| | ACL45015.1 | PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: bid:Bind_0505 oxidoreductase FAD/NAD(P)-binding subunit. (289 aa) |
| | cobQ | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (502 aa) |
| | ACL45111.1 | KEGG: ana:all2333 hypothetical protein. (599 aa) |
| | ACL45114.1 | KEGG: npu:Npun_F2861 hypothetical protein. (136 aa) |
| | ACL45146.1 | PFAM: histidine kinase HAMP region domain protein; KEGG: amr:AM1_0395 sensory transduction histidine kinase. (371 aa) |
| | ACL45232.1 | Protoporphyrinogen oxidase-like protein; KEGG: hne:HNE_0966 hypothetical protein. (496 aa) |
| | ACL45243.1 | Cobaltochelatase, CobN subunit; KEGG: ter:Tery_0132 cobaltochelatase; TIGRFAM: cobaltochelatase, CobN subunit; PFAM: CobN/magnesium chelatase. (1348 aa) |
| | ACL45282.1 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: gsu:GSU1572 riboflavin biosynthesis protein RibD domain-containing protein. (177 aa) |
| | ACL45297.1 | KEGG: ter:Tery_0192 hypothetical protein. (175 aa) |
| | ACL45393.1 | PFAM: Radical SAM domain protein; KEGG: ana:all2029 heme biosynthesis protein. (418 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (230 aa) |
| | thiC | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (458 aa) |
| | ACL45554.1 | PFAM: aldo/keto reductase; KEGG: sth:STH658 oxidoreductase. (277 aa) |
| | ACL45555.1 | Conserved hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (242 aa) |
| | ACL45585.1 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: gvi:gll2708 RNA polymerase ECF-type (group 3) sigma factor. (191 aa) |
| | ACL45586.1 | PFAM: protein of unknown function DUF1486; KEGG: ava:Ava_4985 steroid delta-5-3-ketosteroid isomerase. (137 aa) |
| | ACL45615.1 | Nucleotide sugar dehydrogenase; KEGG: ava:Ava_4589 UDP-glucose/GDP-mannose dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. (457 aa) |
| | ACL45616.1 | PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: tel:tll0665 dTDP-glucose 4,6-dehydratase. (321 aa) |
| | coaD | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (169 aa) |
| | ACL45654.1 | TIGRFAM: MoaD family protein; PFAM: thiamineS protein; KEGG: ana:asl4353 molybdenum cofactor biosynthesis protein D. (88 aa) |
| | panC/cmk | Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family. (529 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: amr:AM1_0430 phosphoribosylaminoimidazole synthetase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. (367 aa) |
| | cobS | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (256 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (432 aa) |
| | mtnP | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (290 aa) |
| | ACL45872.1 | PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: npu:Npun_F3487 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (189 aa) |
| | ACL45879.1 | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: ava:Ava_2921 cobalamin (vitamin B12) biosynthesis CbiX protein. (250 aa) |
| | ACL45880.1 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mar:MAE_47270 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (261 aa) |
| | ACL45883.1 | FHA domain containing protein; PFAM: Forkhead-associated protein; KEGG: amr:AM1_3967 adenylate/guanylate cyclase. (110 aa) |
| | ACL45898.1 | KEGG: mar:MAE_20590 hypothetical protein. (458 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (782 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (503 aa) |
| | chlB | Light-independent protochlorophyllide reductase, B subunit; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (ChlN-ChlB) is the catalytic component of the complex. (507 aa) |
| | ACL46074.1 | Adenylate/guanylate cyclase with Chase sensor; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; KEGG: tel:tll2280 adenylate cyclase. (678 aa) |
| | pyrB | TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: amr:AM1_1883 aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (323 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (203 aa) |
| | ACL46111.1 | PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; KEGG: amr:AM1_0830 hypothetical protein. (377 aa) |
| | ACL46162.1 | Chlorophyll synthase, ChlG; TIGRFAM: bacteriochlorophyll/chlorophyll synthetase; chlorophyll synthase, ChlG; PFAM: UbiA prenyltransferase; KEGG: ana:all4480 chlorophyll synthase 33 kD subunit. (340 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (306 aa) |
| | ACL46203.1 | Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (187 aa) |
| | acsA | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (657 aa) |
| | ACL46215.1 | PFAM: aminotransferase class-III; KEGG: tel:tlr0408 omega-amino acid:pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (444 aa) |
| | ndk | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (149 aa) |
| | chlL | Light-independent protochlorophyllide reductase, iron-sulfur ATP-binding protein; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP. (286 aa) |
| | chlN | Light-independent protochlorophyllide reductase, N subunit; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (ChlN-ChlB) is the catalytic component of the complex. (468 aa) |
| | ACL46265.1 | RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: tel:tlr0738 group 3 RNA polymerase sigma factor. (262 aa) |
| | nusG | NusG antitermination factor; Participates in transcription elongation, termination and antitermination. (217 aa) |
| | coaX | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (264 aa) |
| | ACL46341.1 | KEGG: npu:Npun_F4164 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; Belongs to the PdxA family. (327 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (287 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (233 aa) |
| | dxs | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (632 aa) |
| | ACL46543.1 | TIGRFAM: IMP dehydrogenase family protein; PFAM: IMP dehydrogenase/GMP reductase; KEGG: ava:Ava_2653 inositol-5-monophosphate dehydrogenase. (391 aa) |
| | ACL46546.1 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: tel:tll1829 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (431 aa) |
| | ACL46590.1 | KEGG: cyb:CYB_2833 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. (279 aa) |
| | ACL47535.1 | TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; KEGG: ava:Ava_1817 precorrin-6B methylase. (200 aa) |
| | queE | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (268 aa) |
| | ACL47497.1 | KEGG: pgn:PGN_1298 hypothetical protein. (146 aa) |
| | queC | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (229 aa) |
| | ACL47483.1 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (181 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (395 aa) |
| | ACL47427.1 | TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: amr:AM1_2859 cobalt-precorrin-6x reductase. (254 aa) |
| | ACL47419.1 | Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa) |
| | ACL47388.1 | TIGRFAM: deoxycytidine triphosphate deaminase; KEGG: npu:Npun_F2524 deoxycytidine triphosphate deaminase. (198 aa) |
| | ACL47387.1 | KEGG: npu:Npun_F2523 cob(I)alamin adenosyltransferase. (178 aa) |
| | trpC | PFAM: Indole-3-glycerol phosphate synthase; KEGG: amr:AM1_4360 indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (302 aa) |
| | ACL47333.1 | TIGRFAM: glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase; KEGG: amr:AM1_4291 glycine oxidase ThiO. (360 aa) |
| | atpD | ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (485 aa) |
| | atpC | ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (138 aa) |
| | ACL47310.1 | PFAM: thiamineS protein; KEGG: amr:AM1_0919 thiamineS protein, putative. (91 aa) |
| | ACL47281.1 | KEGG: scl:sce1431 hypothetical protein. (262 aa) |
| | ACL47280.1 | KEGG: scl:sce1430 hypothetical protein. (464 aa) |
| | ACL47279.1 | KEGG: tel:tlr0271 magnesium protoporphyrin IX chelatase subunit H; TIGRFAM: magnesium chelatase, H subunit; PFAM: CobN/magnesium chelatase. (1330 aa) |
| | ACL47275.1 | PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: tel:tll1299 dihydrolipoamide S-acetyltransferase. (432 aa) |
| | nadA | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (322 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (322 aa) |
| | ACL47213.1 | KEGG: ava:Ava_2114 hypothetical protein. (173 aa) |
| | nadK-2 | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (306 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (410 aa) |
| | pcyA | Ferredoxin-dependent bilin reductase; Catalyzes the four-electron reduction of biliverdin IX-alpha (2-electron reduction at both the A and D rings); the reaction proceeds via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin. Belongs to the HY2 family. (259 aa) |
| | ACL47147.1 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: npu:Npun_R1866 uroporphyrin-III C-methyltransferase. (520 aa) |
| | ACL47121.1 | cob(I)alamin adenosyltransferase; KEGG: syf:Synpcc7942_0957 cob(I)yrinic acid a,c-diamide adenosyltransferase; TIGRFAM: cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. (216 aa) |
| | acsF-2 | Magnesium-protoporphyrin IX monomethyl ester aerobic oxidative cyclase; Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME); Belongs to the AcsF family. (355 aa) |
| | ACL47084.1 | KEGG: ava:Ava_4393 coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (465 aa) |
| | ACL47083.1 | Response regulator receiver protein; KEGG: rrs:RoseRS_0942 magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase; TIGRFAM: magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase; PFAM: response regulator receiver; cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (675 aa) |
| | ACL47074.1 | Hypothetical protein. (103 aa) |
| | lipA-2 | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (306 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (330 aa) |
| | ACL47034.1 | PFAM: BolA family protein; KEGG: npu:Npun_R3910 BolA family protein; Belongs to the BolA/IbaG family. (85 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (411 aa) |
| | ACL47025.1 | KEGG: npu:Npun_F6540 hypothetical protein. (264 aa) |
| | proA-2 | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (426 aa) |
| | dacA | Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (327 aa) |
| | ACL46989.1 | TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; KEGG: ana:alr3444 putative DNA polymerase III, delta subunit. (328 aa) |
| | ACL42747.1 | PFAM: PUCC protein; major facilitator superfamily MFS_1; KEGG: tel:tlr0140 similar to light-harvesting 1 (B870) complex assembly protein PucC. (488 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (424 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (242 aa) |
| | ACL46927.1 | PFAM: ferrochelatase; KEGG: ter:Tery_0602 ferrochelatase; Belongs to the ferrochelatase family. (403 aa) |
| | ACL46866.1 | Conserved hypothetical protein; KEGG: ana:alr3583 unknown protein. (207 aa) |
| | ACL46859.1 | PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: tel:tll1325 hypothetical protein. (213 aa) |
| | pdxJ | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (240 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (387 aa) |
| | ACL46823.1 | Molybdenum cofactor synthesis domain protein; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (174 aa) |
| | purC | KEGG: ana:alr2268 phosphoribosylaminoimidazolesuccinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. (242 aa) |
| | ACL46790.1 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (698 aa) |
| | ACL46775.1 | PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: gvi:gll1135 hypothetical protein. (480 aa) |
| | ACL46757.1 | PFAM: protein of unknown function DUF201; KEGG: npu:Npun_R4714 hypothetical protein. (427 aa) |
| | ACL46743.1 | KEGG: pin:Ping_3621 uridine kinase. (209 aa) |
| | ACL46739.1 | PFAM: phosphoribulokinase/uridine kinase; KEGG: cyb:CYB_0441 phosphoribulokinase. (313 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (349 aa) |
| | ACL46717.1 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: npu:Npun_F1237 deaminase-reductase domain-containing protein. (228 aa) |
| | ACL46698.1 | TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: mar:MAE_50290 riboflavin synthase subunit alpha. (222 aa) |
| | lipA | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (307 aa) |
| | ACL46680.1 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. (347 aa) |
| | ACL46669.1 | KEGG: amr:AM1_1737 FolC bifunctional protein (includes: folylpolyglutamate synthetase and dihydrofolate synthetase); TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain protein; Belongs to the folylpolyglutamate synthase family. (427 aa) |
| | ACL46665.1 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (392 aa) |
| | hemL | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: amr:AM1_0549 glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (432 aa) |
| | nusB | NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (209 aa) |
| | acsF | Magnesium-protoporphyrin IX monomethyl ester aerobic oxidative cyclase; Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME); Belongs to the AcsF family. (358 aa) |
| | ACL46647.1 | TIGRFAM: uracil phosphoribosyltransferase; KEGG: tel:tlr1764 uracil phosphoribosyltransferase; Belongs to the UPRTase family. (216 aa) |
| | ACL46644.1 | KEGG: gvi:glr3934 DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein. (1162 aa) |
| | ACL46638.1 | TIGRFAM: cobalamin biosynthesis protein CobW; PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: ana:all3392 cobalamin synthesis protein. (358 aa) |
| | ACL43292.1 | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (418 aa) |
| | moaA | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (329 aa) |
| | ACL43251.1 | PFAM: glutamine amidotransferase class-I; KEGG: amr:AM1_0995 glutamine amidotransferase, class I, putative. (246 aa) |
| | ACL43242.1 | PFAM: Forkhead-associated protein; adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: tel:tll2410 adenylate cyclase. (350 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (982 aa) |
| | ACL43212.1 | TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH; PFAM: Radical SAM domain protein; KEGG: tel:tll0596 probable heme d1 biosynthesis protein NirJ. (337 aa) |
| | pyrD | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (375 aa) |
| | comB | PFAM: 2-phosphosulfolactate phosphatase; KEGG: npu:Npun_R4542 2-phosphosulfolactate phosphatase; Belongs to the ComB family. (244 aa) |
| | ACL43201.1 | PFAM: thymidylate synthase; KEGG: cyt:cce_0382 hypothetical protein. (508 aa) |
| | ACL43185.1 | Magnesium chelatase ATPase subunit D; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. (664 aa) |
| | ACL43161.1 | PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: npu:Npun_F5749 pyridoxamine 5'-phosphate oxidase-related, FMN-binding. (193 aa) |
| | trpF | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: cyt:cce_0998 N-(5'-phosphoribosyl) anthranilate isomerase; Belongs to the TrpF family. (219 aa) |
| | ACL43118.1 | KEGG: cyb:CYB_0478 purine phosphoribosyltransferase, putative. (198 aa) |
| | ACL43113.1 | PFAM: UbiA prenyltransferase; KEGG: ava:Ava_3472 tocopherol phytyltransferase. (314 aa) |
| | ACL43077.1 | PFAM: cobalbumin biosynthesis protein; KEGG: ava:Ava_3872 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase. (193 aa) |
| | ACL43063.1 | PFAM: Rho termination factor domain protein; KEGG: tel:tll2067 hypothetical protein. (413 aa) |
| | ACL42973.1 | KEGG: amr:AM1_3314 hypothetical protein. (137 aa) |
| | ACL42959.1 | RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (372 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (836 aa) |
| | ACL42938.1 | PFAM: molybdopterin biosynthesis MoaE protein; KEGG: ana:all1638 molybdopterin converting factor, subunit 2. (161 aa) |
| | thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (329 aa) |
| | rpoB | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1099 aa) |
| | rpoC1 | DNA-directed RNA polymerase, gamma subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (622 aa) |
| | rpoC2 | DNA-directed RNA polymerase, beta'' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily. (1335 aa) |
| | bioF | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (399 aa) |
| | ACL42870.1 | PFAM: conserved hypothetical protein; KEGG: ava:Ava_2765 hypothetical protein. (195 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (433 aa) |
| | ACL46609.1 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (298 aa) |
| | ACL46608.1 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (181 aa) |
| | folE | PFAM: GTP cyclohydrolase I; KEGG: tel:tll1309 GTP cyclohydrolase I. (235 aa) |
| | cobD | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (332 aa) |
| | ACL42819.1 | PFAM: DRTGG domain protein; KEGG: npu:Npun_R4741 DRTGG domain-containing protein. (362 aa) |
| | ACL42821.1 | PFAM: Radical SAM domain protein; KEGG: amr:AM1_4577 hypothetical protein. (324 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (173 aa) |
| | ACL42823.1 | SMART: Hedgehog/intein hint domain protein; AAA ATPase; KEGG: syn:sll1360 DNA polymerase III subunit gamma/tau [Contains: Ssp dnaX intein]. (1232 aa) |
| | ACL42824.1 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: ana:alr4554 6-pyruvoyl-tetrahydropterin synthase homolog. (294 aa) |
| | ACL42849.1 | KEGG: tel:tll1399 hypothetical protein. (520 aa) |
