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BF93_11520 BF93_11520 sucD sucD pckG pckG BF93_18140 BF93_18140 BF93_10490 BF93_10490 aspA aspA sucC sucC BF93_01255 BF93_01255 BF93_01260 BF93_01260 BF93_01265 BF93_01265 BF93_01270 BF93_01270 BF93_02335 BF93_02335 mqo mqo BF93_03235 BF93_03235 BF93_03240 BF93_03240 BF93_03245 BF93_03245 BF93_04620 BF93_04620 BF93_04625 BF93_04625 BF93_04630 BF93_04630 BF93_06380 BF93_06380 BF93_06495 BF93_06495 BF93_06500 BF93_06500 acnA acnA kgd kgd
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BF93_11520Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. (742 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa)
pckGHypothetical protein; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (412 aa)
BF93_18140Catalyzes the reduction of mycothione or glutathione to mycothione or glutathione disulfide; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
BF93_10490Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (516 aa)
aspAAspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (469 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)
BF93_01255Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (252 aa)
BF93_01260Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (591 aa)
BF93_01265Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa)
BF93_01270Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)
BF93_02335Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (465 aa)
mqoMalate:quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (496 aa)
BF93_03235Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (438 aa)
BF93_03240Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
BF93_03245Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
BF93_04620Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
BF93_046252-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
BF93_04630Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (493 aa)
BF93_06380Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (916 aa)
BF93_06495Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (599 aa)
BF93_06500Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
acnAAconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (928 aa)
kgdAlpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology. (1148 aa)
Your Current Organism:
Brachybacterium phenoliresistens
NCBI taxonomy Id: 396014
Other names: B. phenoliresistens, BCRC 17589, Brachybacterium phenoliresistens Chou et al. 2007, Brachybacterium sp. phenol-A, JCM 15157, LMG 23707, LMG:23707, strain phenol-A
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