STRINGSTRING
ORB29237.1 ORB29237.1 recG recG ORB31678.1 ORB31678.1 ORB32014.1 ORB32014.1 BST38_04720 BST38_04720 ORB31127.1 ORB31127.1 ORB31136.1 ORB31136.1 ORB31176.1 ORB31176.1 recF recF dnaX dnaX recR recR ORB30840.1 ORB30840.1 ORB30416.1 ORB30416.1 ORB29968.1 ORB29968.1 ORB29992.1 ORB29992.1 ORB29997.1 ORB29997.1 ORB29998.1 ORB29998.1 ORB29719.1 ORB29719.1 ORB29103.1 ORB29103.1 ORB29108.1 ORB29108.1 ORB29109.1 ORB29109.1 ORB28456.1 ORB28456.1 recO recO priA-2 priA-2 dnaE2 dnaE2 ORB27849.1 ORB27849.1 ruvB ruvB ruvA ruvA ruvC ruvC ORB27659.1 ORB27659.1 recC recC recB recB recD recD ORB27575.1 ORB27575.1 ORB26636.1 ORB26636.1 polA polA ORB25873.1 ORB25873.1 recA recA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ORB29237.1Cell filamentation protein Fic; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (756 aa)
ORB31678.1DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (755 aa)
ORB32014.1DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
BST38_04720Hypothetical protein; Frameshifted; internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
ORB31127.1MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
ORB31136.1Single-stranded DNA-binding protein; Binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa)
ORB31176.1DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (398 aa)
recFDNA replication/repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (386 aa)
dnaXDNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (670 aa)
recRRecombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (203 aa)
ORB30840.13'-5' exonuclease of DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
ORB30416.1DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1180 aa)
ORB29968.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
ORB29992.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (578 aa)
ORB29997.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (152 aa)
ORB29998.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (285 aa)
ORB29719.1Single-stranded DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (169 aa)
ORB29103.1Flap endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
ORB29108.1Protein pafC; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
ORB29109.1WYL domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
ORB28456.1DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
recODNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. (273 aa)
priA-2Primosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (666 aa)
dnaE2Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1097 aa)
ORB27849.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
ruvBHolliday junction branch migration DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (355 aa)
ruvAHolliday junction branch migration protein RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (195 aa)
ruvCCrossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (197 aa)
ORB27659.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
recCExodeoxyribonuclease V subunit gamma; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] (1087 aa)
recBExodeoxyribonuclease V subunit beta; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and rep [...] (1099 aa)
recDExodeoxyribonuclease V subunit alpha; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] (562 aa)
ORB27575.1Hypothetical protein; Contains 3'-5'exonuclease domain; Derived by automated computational analysis using gene prediction method: Protein Homology. (613 aa)
ORB26636.1DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (909 aa)
ORB25873.1AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (777 aa)
recARecombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (350 aa)
Your Current Organism:
Mycolicibacterium parafortuitum
NCBI taxonomy Id: 39692
Other names: ATCC 19686, CCUG 20999, CIP 106802, DSM 43528, JCM 6367, M. parafortuitum, Mycobacterium parafortuitum, NCTC 10411, NRRL B-4035
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