STRINGSTRING
Aave_0065 Aave_0065 Aave_0245 Aave_0245 Aave_0273 Aave_0273 Aave_0309 Aave_0309 Aave_0314 Aave_0314 Aave_0351 Aave_0351 Aave_0426 Aave_0426 Aave_0434 Aave_0434 Aave_0435 Aave_0435 Aave_0436 Aave_0436 apaG apaG Aave_0652 Aave_0652 Aave_0739 Aave_0739 Aave_0740 Aave_0740 Aave_0809 Aave_0809 Aave_0832 Aave_0832 Aave_0844 Aave_0844 Aave_0862 Aave_0862 Aave_0932 Aave_0932 Aave_0933 Aave_0933 Aave_0991 Aave_0991 Aave_1125 Aave_1125 Aave_1150 Aave_1150 Aave_1195 Aave_1195 Aave_1315 Aave_1315 Aave_1316 Aave_1316 Aave_1388 Aave_1388 Aave_1435 Aave_1435 Aave_1443 Aave_1443 Aave_1579 Aave_1579 Aave_1797 Aave_1797 Aave_1802 Aave_1802 Aave_1832 Aave_1832 Aave_1852 Aave_1852 Aave_1853 Aave_1853 Aave_1854 Aave_1854 Aave_1879 Aave_1879 Aave_1882 Aave_1882 Aave_1883 Aave_1883 Aave_1927 Aave_1927 Aave_1996 Aave_1996 Aave_2152 Aave_2152 Aave_2200 Aave_2200 Aave_2205 Aave_2205 tam tam Aave_2208 Aave_2208 Aave_2209 Aave_2209 Aave_2211 Aave_2211 Aave_2280 Aave_2280 Aave_2457 Aave_2457 Aave_2601 Aave_2601 greA greA Aave_2613 Aave_2613 Aave_2633 Aave_2633 Aave_2634 Aave_2634 Aave_2640 Aave_2640 Aave_2641 Aave_2641 Aave_2642 Aave_2642 Aave_2649 Aave_2649 Aave_2804 Aave_2804 Aave_2842 Aave_2842 Aave_2989 Aave_2989 Aave_2991 Aave_2991 Aave_3003 Aave_3003 Aave_3113 Aave_3113 Aave_3114 Aave_3114 Aave_3115 Aave_3115 Aave_3116 Aave_3116 Aave_3118 Aave_3118 Aave_3279 Aave_3279 Aave_3303 Aave_3303 Aave_3304 Aave_3304 Aave_3309 Aave_3309 Aave_3310 Aave_3310 Aave_3317 Aave_3317 Aave_3371 Aave_3371 Aave_3386 Aave_3386 Aave_3604 Aave_3604 Aave_3605 Aave_3605 mutM mutM Aave_3607 Aave_3607 Aave_3608 Aave_3608 Aave_3701 Aave_3701 Aave_3836 Aave_3836 Aave_3837 Aave_3837 Aave_3838 Aave_3838 Aave_3861 Aave_3861 Aave_3904 Aave_3904 Aave_4081 Aave_4081 Aave_4187 Aave_4187 Aave_4194 Aave_4194 Aave_4202 Aave_4202 Aave_4223 Aave_4223 Aave_4280 Aave_4280 Aave_4343 Aave_4343 Aave_4344 Aave_4344 Aave_4432 Aave_4432 Aave_4508 Aave_4508 Aave_4509 Aave_4509 Aave_4525 Aave_4525 Aave_4526 Aave_4526 Aave_4527 Aave_4527 Aave_4528 Aave_4528 Aave_4529 Aave_4529 Aave_4597 Aave_4597 Aave_4620 Aave_4620 Aave_4630 Aave_4630 Aave_4639 Aave_4639 Aave_4642 Aave_4642 Aave_4666 Aave_4666 Aave_4671 Aave_4671 Aave_4672 Aave_4672 Aave_4678 Aave_4678 def-2 def-2 Aave_4689 Aave_4689 Aave_4691 Aave_4691 Aave_4692 Aave_4692 Aave_4760 Aave_4760 Aave_4761 Aave_4761
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Aave_0065KEGG: rfr:Rfer_0054 methyltransferase type 12. (271 aa)
Aave_0245KEGG: pol:Bpro_1033 hypothetical protein. (319 aa)
Aave_0273PFAM: protein of unknown function DUF1228; KEGG: pol:Bpro_1488 protein of unknown function DUF1228. (427 aa)
Aave_0309KEGG: pol:Bpro_0233 putative lipoprotein. (220 aa)
Aave_0314TIGRFAM: hemerythrin-like metal-binding protein; PFAM: Hemerythrin HHE cation binding domain protein; KEGG: reu:Reut_A0820 hypothetical protein. (171 aa)
Aave_0351KEGG: pol:Bpro_0295 hypothetical protein. (189 aa)
Aave_0426PFAM: SEC-C motif domain protein; KEGG: reu:Reut_B5710 sec-C motif. (278 aa)
Aave_0434Uncharacterized enzyme; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (374 aa)
Aave_0435Transporter, CPA2 family (2.A.37); PFAM: sodium/hydrogen exchanger; KEGG: pol:Bpro_4469 sodium/hydrogen exchanger; TC 2.A.37. (419 aa)
Aave_0436KEGG: rfr:Rfer_0530 putative site-specific recombinase transmembrane protein. (663 aa)
apaGPFAM: ApaG domain protein; KEGG: pol:Bpro_4467 ApaG. (136 aa)
Aave_0652KEGG: pol:Bpro_0441 hypothetical protein. (274 aa)
Aave_0739KEGG: pol:Bpro_0443 hypothetical protein. (95 aa)
Aave_0740KEGG: pol:Bpro_0444 hypothetical protein. (231 aa)
Aave_0809KEGG: pol:Bpro_1065 hypothetical protein. (602 aa)
Aave_0832KEGG: rfr:Rfer_2431 integral membrane protein-like. (167 aa)
Aave_0844PFAM: O-antigen polymerase; KEGG: pol:Bpro_4672 O-antigen polymerase. (556 aa)
Aave_0862KEGG: rfr:Rfer_3349 histone protein. (212 aa)
Aave_0932PFAM: porin, Gram-negative type; KEGG: pol:Bpro_3679 porin, gram-negative type. (344 aa)
Aave_0933PFAM: porin, Gram-negative type; KEGG: rme:Rmet_4834 porin, gram-negative type. (374 aa)
Aave_0991PFAM: beta-lactamase domain protein; KEGG: reu:Reut_A0043 beta-lactamase-like. (278 aa)
Aave_1125PFAM: porin, Gram-negative type; KEGG: rso:RS00714 probable porin precursor transmembrane protein. (341 aa)
Aave_1150PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: rso:RS00711 putative HNS-like transcription regulator protein. (99 aa)
Aave_1195KEGG: rfr:Rfer_1742 putative transmembrane protein. (133 aa)
Aave_1315Diguanylate phosphodiesterase; PFAM: EAL domain protein; HDOD; KEGG: mfa:Mfla_1965 diguanylate phosphodiesterase (EAL domain). (449 aa)
Aave_1316Diguanylate phosphodiesterase; PFAM: EAL domain protein; HDOD; KEGG: cvi:CV3451 putative signal transduction protein containing EAL and modified HD-GYP domains. (419 aa)
Aave_1388KEGG: pol:Bpro_3120 putative transcriptional regulator. (111 aa)
Aave_1435PFAM: phosphoribosyltransferase; KEGG: rfr:Rfer_2295 phosphoribosyltransferase. (174 aa)
Aave_1443KEGG: rfr:Rfer_2980 conserved hypothetical signal peptide protein. (172 aa)
Aave_1579KEGG: rme:Rmet_1193 hypothetical protein. (224 aa)
Aave_1797PFAM: peptidase M14, carboxypeptidase A; KEGG: pol:Bpro_2152 peptidase M14, carboxypeptidase A. (618 aa)
Aave_1802KEGG: rfr:Rfer_2170 hypothetical protein. (747 aa)
Aave_1832PFAM: outer membrane chaperone Skp (OmpH); KEGG: pol:Bpro_2686 outer membrane chaperone Skp (OmpH); Belongs to the skp family. (175 aa)
Aave_1852Putative metal dependent phosphohydrolase; KEGG: rfr:Rfer_2693 HD-GYP domain-like. (349 aa)
Aave_1853KEGG: pol:Bpro_1595 hypothetical protein. (214 aa)
Aave_1854PFAM: protein of unknown function DUF520; KEGG: rfr:Rfer_2692 protein of unknown function DUF520; Belongs to the UPF0234 family. (161 aa)
Aave_1879PFAM: OmpA domain protein transmembrane region-containing protein; KEGG: pol:Bpro_2709 OmpA-like transmembrane region. (200 aa)
Aave_1882KEGG: rfr:Rfer_1400 hypothetical protein. (153 aa)
Aave_1883PFAM: GCN5-related N-acetyltransferase; KEGG: pol:Bpro_1689 GCN5-related N-acetyltransferase. (197 aa)
Aave_1927KEGG: pol:Bpro_1726 hypothetical protein. (271 aa)
Aave_1996PFAM: HemY domain protein; KEGG: pol:Bpro_3661 putative porphyrin biosynthesis related protein. (425 aa)
Aave_2152Molecular chaperone; PFAM: CS; KEGG: pol:Bpro_3264 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. (124 aa)
Aave_2200PFAM: protein of unknown function DUF339; KEGG: pol:Bpro_3604 protein of unknown function DUF339. (97 aa)
Aave_2205Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein; KEGG: pol:Bpro_3599 transcriptional regulator, GntR family. (278 aa)
tamTrans-aconitate 2-methyltransferase; Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate. (260 aa)
Aave_2208PFAM: HpcH/HpaI aldolase; KEGG: pol:Bpro_3597 HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family. (341 aa)
Aave_2209KEGG: pol:Bpro_3596 hypothetical protein. (236 aa)
Aave_2211PFAM: SbmABacA family protein; ABC transporter domain protein; KEGG: bmb:BruAb1_0398 BacA, bacteroid development protein. (340 aa)
Aave_2280PFAM: phosphoesterase, DHHA1; KEGG: rfr:Rfer_1390 phosphoesterase, DHHA1. (320 aa)
Aave_2457PFAM: glutaredoxin; KEGG: pol:Bpro_2856 glutaredoxin. (213 aa)
Aave_2601KEGG: mlo:mlr7906 hypothetical protein. (166 aa)
greATranscription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (158 aa)
Aave_2613KEGG: rfr:Rfer_2008 hypothetical protein. (136 aa)
Aave_2633TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: pol:Bpro_2259 MATE efflux family protein. (458 aa)
Aave_2634KEGG: rfr:Rfer_2901 putative inner membrane transmembrane protein. (581 aa)
Aave_2640KEGG: rfr:Rfer_2897 hypothetical protein. (883 aa)
Aave_2641DNA helicase/exodeoxyribonuclease V, subunit A; PFAM: UvrD/REP helicase; KEGG: pol:Bpro_2265 UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. (1168 aa)
Aave_2642PFAM: HI0933 family protein; FAD dependent oxidoreductase; KEGG: pol:Bpro_2266 HI0933-like protein. (482 aa)
Aave_2649KEGG: bxe:Bxe_A3305 hypothetical protein. (50 aa)
Aave_2804PFAM: Auxin Efflux Carrier; KEGG: pol:Bpro_1684 auxin efflux carrier. (322 aa)
Aave_2842SMART: ZipA, C-terminal FtsZ-binding region; KEGG: rfr:Rfer_2200 hypothetical protein. (374 aa)
Aave_2989KEGG: rfr:Rfer_2656 hypothetical protein. (898 aa)
Aave_2991PFAM: Lytic transglycosylase, catalytic; KEGG: rfr:Rfer_2657 lytic transglycosylase, catalytic. (295 aa)
Aave_3003PFAM: Calcium/calmodulin dependent protein kinase II, association-domain protein; KEGG: rso:RS03100 hypothetical signal peptide protein. (159 aa)
Aave_3113RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: pol:Bpro_2316 sigma-24 (FecI-like); Belongs to the sigma-70 factor family. ECF subfamily. (189 aa)
Aave_3114KEGG: rfr:Rfer_3320 putative transmembrane protein. (154 aa)
Aave_3115Hypothetical protein; KEGG: rfr:Rfer_3319 putative transmembrane protein. (290 aa)
Aave_3116PFAM: RDD domain containing protein; KEGG: pol:Bpro_2313 hypothetical protein. (189 aa)
Aave_3118PFAM: conserved hypothetical protein 730; KEGG: pol:Bpro_2311 conserved hypothetical protein 730; Belongs to the LOG family. (207 aa)
Aave_3279PFAM: OmpA/MotB domain protein; KEGG: pol:Bpro_1796 OmpA/MotB. (219 aa)
Aave_3303PFAM: major facilitator superfamily MFS_1; KEGG: pol:Bpro_3076 major facilitator superfamily MFS_1. (414 aa)
Aave_3304PFAM: protein of unknown function DUF195; KEGG: bbr:BB3410 conserved hypothetical lipoprotein. (474 aa)
Aave_3309TIGRFAM: phasin family protein; KEGG: pol:Bpro_3088 phasin. (192 aa)
Aave_3310PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: pol:Bpro_3050 hypothetical protein. (91 aa)
Aave_3317KEGG: rfr:Rfer_2777 hypothetical protein. (115 aa)
Aave_3371KEGG: pol:Bpro_2439 hypothetical protein. (182 aa)
Aave_3386KEGG: pol:Bpro_1834 hypothetical protein. (134 aa)
Aave_3604A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs. (363 aa)
Aave_3605KEGG: pol:Bpro_1298 hypothetical protein. (653 aa)
mutMDNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (271 aa)
Aave_3607PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: pol:Bpro_1296 tetratricopeptide TPR_4. (584 aa)
Aave_3608KEGG: pol:Bpro_1295 putative lipoprotein. (174 aa)
Aave_3701KEGG: rfr:Rfer_3233 hypothetical protein. (318 aa)
Aave_3836PFAM: protein of unknown function DUF161; KEGG: ret:RHE_CH00545 hypothetical protein. (237 aa)
Aave_3837KEGG: pol:Bpro_0908 putative lipoprotein. (189 aa)
Aave_3838KEGG: pol:Bpro_0907 hypothetical protein. (67 aa)
Aave_3861PFAM: response regulator receiver; KEGG: pol:Bpro_0882 response regulator receiver domain protein (CheY-like). (131 aa)
Aave_3904KEGG: rfr:Rfer_1683 putative transmembrane protein. (75 aa)
Aave_4081PFAM: protein of unknown function DUF583; KEGG: rfr:Rfer_3896 protein of unknown function DUF583. (186 aa)
Aave_4187PFAM: GCN5-related N-acetyltransferase; KEGG: pol:Bpro_4211 GCN5-related N-acetyltransferase. (222 aa)
Aave_4194Acetyltransferase and hydrolase with the alpha/beta hydrolase fold-like protein; KEGG: pol:Bpro_4221 putative lipase transmembrane protein. (430 aa)
Aave_4202PFAM: beta-lactamase domain protein; KEGG: rfr:Rfer_3580 beta-lactamase-like. (317 aa)
Aave_4223KEGG: rfr:Rfer_0811 hypothetical protein. (64 aa)
Aave_4280PFAM: Carbohydrate-selective porin OprB; KEGG: rme:Rmet_0352 carbohydrate-selective porin OprB. (478 aa)
Aave_4343PFAM: porin, Gram-negative type; KEGG: rme:Rmet_1907 porin, gram-negative type. (329 aa)
Aave_4344PFAM: porin, Gram-negative type; KEGG: reu:Reut_B5850 porin, gram-negative type. (340 aa)
Aave_4432PFAM: HDOD; KEGG: cvi:CV3451 putative signal transduction protein containing EAL and modified HD-GYP domains. (409 aa)
Aave_4508PFAM: domain of unknown function DUF1745; KEGG: rfr:Rfer_0622 hypothetical protein. (439 aa)
Aave_4509KEGG: pol:Bpro_0449 hypothetical protein. (314 aa)
Aave_4525Two component transcriptional regulator, Fis family; PFAM: response regulator receiver; helix-turn-helix, Fis-type; KEGG: reu:Reut_A3402 helix-turn-helix, fis-type. (238 aa)
Aave_4526Multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein; SMART: PAS domain containing protein; KEGG: rfr:Rfer_3588 multi-sensor signal transduction histidine kinase. (772 aa)
Aave_4527KEGG: rfr:Rfer_3589 putative proline rich signal peptide protein. (217 aa)
Aave_4528TIGRFAM: sun protein; PFAM: Fmu (Sun) domain protein; KEGG: pol:Bpro_4436 sun protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (461 aa)
Aave_4529LemA; KEGG: pol:Bpro_4440 LemA. (197 aa)
Aave_4597Peptidase C26; PFAM: glutamine amidotransferase class-I; peptidase C26; KEGG: pol:Bpro_4701 peptidase C26. (307 aa)
Aave_4620PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: ade:Adeh_0453 methyltransferase type 12. (201 aa)
Aave_4630PFAM: Sporulation domain protein; KEGG: pol:Bpro_4717 putative signal peptide protein. (247 aa)
Aave_4639PFAM: regulatory protein, MarR; KEGG: pol:Bpro_4686 transcriptional regulator, MarR family. (186 aa)
Aave_4642KEGG: rfr:Rfer_3864 hypothetical protein. (795 aa)
Aave_4666Putative metal dependent phosphohydrolase; KEGG: rfr:Rfer_4051 HD-GYP domain-like. (403 aa)
Aave_4671KEGG: pol:Bpro_4663 hypothetical protein. (105 aa)
Aave_4672PFAM: protein of unknown function DUF1289; KEGG: pol:Bpro_4664 protein of unknown function DUF1289. (146 aa)
Aave_4678KEGG: rfr:Rfer_1264 O-antigen polymerase. (556 aa)
def-2Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (169 aa)
Aave_4689KEGG: pol:Bpro_0388 putative lipoprotein transmembrane. (167 aa)
Aave_4691PFAM: AzlC family protein; KEGG: pol:Bpro_4637 AzlC-like. (288 aa)
Aave_4692PFAM: branched-chain amino acid transport; KEGG: pol:Bpro_4636 branched-chain amino acid transport. (111 aa)
Aave_4760PFAM: guanine-specific ribonuclease N1 and T1; KEGG: pol:Bpro_4859 guanyl-specific ribonuclease SA. (134 aa)
Aave_4761KEGG: pol:Bpro_4860 hypothetical protein. (139 aa)
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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