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lptA lptA Aave_0418 Aave_0418 Aave_0631 Aave_0631 lpxC lpxC Aave_0980 Aave_0980 Aave_0981 Aave_0981 kdsA kdsA Aave_1336 Aave_1336 bamB bamB bamA bamA lpxD lpxD fabZ fabZ lpxA lpxA lpxB lpxB kdsB kdsB lpxK lpxK Aave_2820 Aave_2820 Aave_3163 Aave_3163 Aave_3164 Aave_3164 bamD bamD Aave_4175 Aave_4175 lptE lptE bamE bamE lptD lptD Aave_4783 Aave_4783 Aave_4784 Aave_4784 Aave_4785 Aave_4785
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lptAOstA family protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. (216 aa)
Aave_0418PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: pol:Bpro_4486 ABC transporter-related protein. (263 aa)
Aave_0631KEGG: rfr:Rfer_3874 phosphoheptose isomerase. (200 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (307 aa)
Aave_0980PFAM: lipid A biosynthesis acyltransferase; KEGG: rfr:Rfer_3881 putative acyltransferase. (287 aa)
Aave_0981PFAM: lipid A biosynthesis acyltransferase; KEGG: pol:Bpro_0769 lipid A biosynthesis acyltransferase. (290 aa)
kdsATIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: pol:Bpro_3182 2-dehydro-3-deoxyphosphooctonate aldolase. (285 aa)
Aave_1336PFAM: NlpBDapX family lipoprotein; KEGG: rfr:Rfer_2096 NlpBDapX lipoprotein. (364 aa)
bamBPyrrolo-quinoline quinone; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (385 aa)
bamASurface antigen (D15); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (765 aa)
lpxDUDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (333 aa)
fabZ3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (146 aa)
lpxAacyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (262 aa)
lpxBlipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (383 aa)
kdsB3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (263 aa)
lpxKlipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (347 aa)
Aave_2820Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (450 aa)
Aave_3163PFAM: permease YjgP/YjgQ family protein; KEGG: rfr:Rfer_2115 permease YjgP/YjgQ. (365 aa)
Aave_3164PFAM: permease YjgP/YjgQ family protein; KEGG: rfr:Rfer_2114 permease YjgP/YjgQ. (365 aa)
bamDPutative transmembrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (265 aa)
Aave_4175D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase; TIGRFAM: histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; KEGG: pol:Bpro_4201 histidinol-phosphate phosphatase. (183 aa)
lptERare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family. (168 aa)
bamESmpA/OmlA domain protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (185 aa)
lptDOrganic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Belongs to the LptD family. (820 aa)
Aave_4783PFAM: protein of unknown function DUF1239; KEGG: rfr:Rfer_4235 protein of unknown function DUF1239. (205 aa)
Aave_4784TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; KEGG: pol:Bpro_4897 phosphatase KdsC. (204 aa)
Aave_4785KEGG: rfr:Rfer_4237 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. (339 aa)
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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