STRINGSTRING
Aave_0181 Aave_0181 Aave_0555 Aave_0555 Aave_0558 Aave_0558 Aave_0646 Aave_0646 Aave_0675 Aave_0675 Aave_0676 Aave_0676 mutL mutL Aave_1916 Aave_1916 polA polA mutS mutS sbcD sbcD Aave_2637 Aave_2637 Aave_3185 Aave_3185 Aave_3186 Aave_3186 Aave_3242 Aave_3242 Aave_3773 Aave_3773 Aave_4005 Aave_4005 Aave_4627 Aave_4627 recA recA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Aave_0181KEGG: rfr:Rfer_0459 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. (705 aa)
Aave_0555Hypothetical protein; KEGG: dar:Daro_2290 ATP-binding region, ATPase-like. (523 aa)
Aave_0558KEGG: xac:XAC2212 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. (680 aa)
Aave_0646PFAM: UvrD/REP helicase; KEGG: rru:Rru_A1536 UvrD/REP helicase. (665 aa)
Aave_0675PFAM: UvrD/REP helicase; KEGG: bfs:BF1103 putative ATP-dependent DNA helicase. (599 aa)
Aave_0676KEGG: bfs:BF1102 conserved hypothetical protein with RecF/RecN/SMC N-terminal domain. (712 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (698 aa)
Aave_1916PFAM: UvrD/REP helicase; KEGG: pol:Bpro_1723 UvrD/REP helicase. (818 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (927 aa)
mutSDNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (890 aa)
sbcDExodeoxyribonuclease I subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (406 aa)
Aave_2637PFAM: SMC domain protein; KEGG: dar:Daro_1919 SMC protein, N-terminal. (1164 aa)
Aave_3185KEGG: sat:SYN_02907 ATP-dependent endonuclease family protein. (641 aa)
Aave_3186PFAM: UvrD/REP helicase; KEGG: sat:SYN_02908 ATP-dependent DNA helicase. (603 aa)
Aave_3242SMART: helicase c2; DEAD-like helicases-like; KEGG: rfr:Rfer_2316 helicase C2. (740 aa)
Aave_3773PFAM: DNA repair protein RadC; KEGG: rfr:Rfer_3252 DNA repair protein RadC; Belongs to the UPF0758 family. (237 aa)
Aave_4005KEGG: nmu:Nmul_A2304 ATP-dependent DNA helicase, RecQ family; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. (630 aa)
Aave_4627KEGG: rfr:Rfer_3955 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: SWIB/MDM2 domain protein; TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. (982 aa)
recArecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (354 aa)
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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