STRINGSTRING
Aave_0294 Aave_0294 Aave_0295 Aave_0295 Aave_0296 Aave_0296 mrdA mrdA Aave_0332 Aave_0332 Aave_0415 Aave_0415 mraZ mraZ rsmH rsmH ftsL ftsL ftsI ftsI murE murE murF murF mraY mraY murD murD ftsW ftsW murG murG murC murC ddl ddl ftsQ ftsQ ftsA ftsA ftsZ ftsZ mtgA mtgA mrdB mrdB mpl mpl Aave_0855 Aave_0855 Aave_0995 Aave_0995 murA murA murJ murJ Aave_1169 Aave_1169 Aave_1423 Aave_1423 murB murB Aave_1957 Aave_1957 Aave_2469 Aave_2469 Aave_2650 Aave_2650 Aave_2652 Aave_2652 rnhA rnhA Aave_3237 Aave_3237 Aave_3409 Aave_3409 mltG mltG Aave_3414 Aave_3414 Aave_3977 Aave_3977 Aave_3978 Aave_3978 Aave_3979 Aave_3979 Aave_3980 Aave_3980 Aave_3981 Aave_3981 Aave_3982 Aave_3982 Aave_4046 Aave_4046 anmK anmK rlpA rlpA Aave_4203 Aave_4203 Aave_4204 Aave_4204 Aave_4568 Aave_4568 Aave_4651 Aave_4651 Aave_4652 Aave_4652
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Aave_0294TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: cell shape determining protein MreB/Mrl; KEGG: pol:Bpro_0222 cell shape determining protein, MreB/Mrl family. (347 aa)
Aave_0295Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. (306 aa)
Aave_0296KEGG: pol:Bpro_0224 putative rod shape-determining MreD transmembrane protein. (172 aa)
mrdACell elongation-specific peptidoglycan D,D-transpeptidase; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (648 aa)
Aave_0332Penicillin-binding protein 6; PFAM: beta-lactamase; peptidase S11, D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: pol:Bpro_0250 serine-type D-Ala-D-Ala carboxypeptidase; Serine peptidase; MEROPS family S11; Belongs to the peptidase S11 family. (393 aa)
Aave_0415PFAM: Sporulation domain protein; KEGG: rfr:Rfer_0774 sporulation related. (218 aa)
mraZTIGRFAM: MraZ protein; PFAM: protein of unknown function UPF0040; KEGG: rfr:Rfer_3434 protein of unknown function UPF0040; Belongs to the MraZ family. (165 aa)
rsmHS-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (311 aa)
ftsLCell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (109 aa)
ftsIPeptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (581 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (519 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (501 aa)
mraYPhospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (392 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (667 aa)
ftsWCell division-specific peptidoglycan biosynthesis regulator FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (427 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (355 aa)
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (475 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation. (334 aa)
ftsQPolypeptide-transport-associated domain protein, FtsQ-type; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (275 aa)
ftsACell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (409 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (410 aa)
mtgAMonofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (244 aa)
mrdBCell elongation-specific peptidoglycan biosynthesis regulator RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (386 aa)
mplUDP-N-acetylmuramate; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. (473 aa)
Aave_0855KEGG: pol:Bpro_1097 hypothetical protein. (200 aa)
Aave_0995KEGG: rfr:Rfer_2918 penicillin-binding protein 1A; TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase. (797 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (434 aa)
murJIntegral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (545 aa)
Aave_1169KEGG: pol:Bpro_3568 hypothetical protein. (283 aa)
Aave_1423KEGG: pol:Bpro_2609 hypothetical protein. (318 aa)
murBUDP-N-acetylmuramate dehydrogenase; Cell wall formation. (357 aa)
Aave_1957TIGRFAM: penicillin-binding protein 1C; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase; Penicillin-binding domain protein; KEGG: rme:Rmet_3529 penicillin-binding protein 1C. (784 aa)
Aave_2469PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase; KEGG: rme:Rmet_4835 glycosyl transferase, family 51. (846 aa)
Aave_2650PFAM: Lytic transglycosylase, catalytic; MLTD_N domain protein; KEGG: pol:Bpro_2278 lytic transglycosylase, catalytic. (514 aa)
Aave_2652PFAM: Methyltransferase type 11; KEGG: pol:Bpro_2280 hypothetical protein. (251 aa)
rnhARNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (149 aa)
Aave_3237TIGRFAM: lytic murein transglycosylase; PFAM: Peptidoglycan-binding domain 1 protein; KEGG: rfr:Rfer_0327 lytic murein transglycosylase. (470 aa)
Aave_3409TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: rfr:Rfer_2258 TatD-related deoxyribonuclease. (264 aa)
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (334 aa)
Aave_3414PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: pol:Bpro_2521 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family. (304 aa)
Aave_3977KEGG: rfr:Rfer_0823 hypothetical protein. (145 aa)
Aave_3978KEGG: reu:Reut_A2583 hypothetical protein. (175 aa)
Aave_3979ABC transporter-related protein; PFAM: ABC transporter, transmembrane region; ABC transporter-related protein; SMART: AAA ATPase; KEGG: pol:Bpro_1417 ABC transporter-related protein. (773 aa)
Aave_3980TIGRFAM: cyanophycin synthetase; PFAM: phosphoribosylglycinamide synthetase; RimK domain protein ATP-grasp; KEGG: pol:Bpro_1416 cyanophycin synthetase. (723 aa)
Aave_3981TIGRFAM: cyanophycin synthetase; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; RimK domain protein ATP-grasp; KEGG: pol:Bpro_1415 cyanophycin synthetase. (861 aa)
Aave_3982PFAM: CreA family protein; KEGG: nmu:Nmul_A1715 CreA. (168 aa)
Aave_4046PFAM: peptidase M23B; KEGG: rfr:Rfer_0727 peptidase M23B. (453 aa)
anmKProtein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (378 aa)
rlpARare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (108 aa)
Aave_4203PFAM: Lytic transglycosylase, catalytic; KEGG: pol:Bpro_0652 lytic transglycosylase, catalytic. (660 aa)
Aave_4204PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: rfr:Rfer_1087 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (191 aa)
Aave_4568D-Ala-D-Ala carboxypeptidase PBP3; TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13, D-Ala-D-Ala carboxypeptidase C; KEGG: rfr:Rfer_0191 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; Serine peptidase; MEROPS family S13. (486 aa)
Aave_4651PFAM: MltA domain protein; 3D domain protein; KEGG: rfr:Rfer_0365 MltA. (433 aa)
Aave_4652PFAM: OmpA/MotB domain protein; KEGG: rfr:Rfer_0206 OmpA/MotB. (217 aa)
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.