STRINGSTRING
Aave_0058 Aave_0058 pckG pckG opgD opgD Aave_0235 Aave_0235 Aave_0267 Aave_0267 Aave_0268 Aave_0268 Aave_0287 Aave_0287 Aave_0302 Aave_0302 Aave_0438 Aave_0438 gph gph Aave_0598 Aave_0598 Aave_0599 Aave_0599 Aave_0600 Aave_0600 lpxC lpxC Aave_0871 Aave_0871 pgi pgi Aave_0948 Aave_0948 Aave_0949 Aave_0949 Aave_0952 Aave_0952 Aave_0953 Aave_0953 Aave_0957 Aave_0957 Aave_0958 Aave_0958 Aave_0960 Aave_0960 Aave_0962 Aave_0962 Aave_0963 Aave_0963 Aave_0964 Aave_0964 Aave_1037 Aave_1037 Aave_1038 Aave_1038 Aave_1039 Aave_1039 Aave_1040 Aave_1040 Aave_1041 Aave_1041 Aave_1042 Aave_1042 Aave_1043 Aave_1043 Aave_1206 Aave_1206 Aave_1207 Aave_1207 Aave_1209 Aave_1209 Aave_1210 Aave_1210 tpiA tpiA kdsA kdsA Aave_1382 Aave_1382 lpxD lpxD fabZ fabZ lpxA lpxA lpxB lpxB fbp fbp Aave_2004 Aave_2004 glgE glgE glgB glgB Aave_2065 Aave_2065 Aave_2068 Aave_2068 Aave_2074 Aave_2074 Aave_2172 Aave_2172 Aave_2193 Aave_2193 Aave_2259 Aave_2259 lpxH lpxH Aave_2532 Aave_2532 kdsB kdsB lpxK lpxK Aave_2591 Aave_2591 Aave_2623 Aave_2623 Aave_2634 Aave_2634 Aave_2820 Aave_2820 Aave_2849 Aave_2849 glgC glgC Aave_2984 Aave_2984 glgA glgA gpmA gpmA glmU glmU Aave_4061 Aave_4061 Aave_4063 Aave_4063 Aave_4064 Aave_4064 Aave_4065 Aave_4065 Aave_4140 Aave_4140 Aave_4141 Aave_4141 Aave_4142 Aave_4142 Aave_4164 Aave_4164 Aave_4210 Aave_4210 Aave_4212 Aave_4212 Aave_4328 Aave_4328 Aave_4330 Aave_4330 Aave_4366 Aave_4366 Aave_4407 Aave_4407 Aave_4576 Aave_4576 Aave_4585 Aave_4585 Aave_4610 Aave_4610 Aave_4697 Aave_4697 Aave_4784 Aave_4784
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Aave_0058PFAM: GtrA family protein; KEGG: rso:RSc0167 hypothetical protein. (143 aa)
pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (620 aa)
opgDPeriplasmic glucan biosynthesis protein, MdoG; Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs). Belongs to the OpgD/OpgG family. (534 aa)
Aave_0235Gluconolactonase; PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: rfr:Rfer_0479 senescence marker protein-30 (SMP-30). (323 aa)
Aave_0267PFAM: O-antigen polymerase; KEGG: xac:XAC3797 hypothetical protein. (430 aa)
Aave_0268PFAM: glycosyl transferase, group 1; KEGG: sth:STH1101 glycosyl transferase. (387 aa)
Aave_0287PFAM: aldo/keto reductase; KEGG: rso:RSc1154 putative reductase oxidoreductase protein. (277 aa)
Aave_0302KEGG: pol:Bpro_4369 L-serine dehydratase 1; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. (462 aa)
Aave_0438PFAM: ribulose-phosphate 3-epimerase; KEGG: rfr:Rfer_0532 ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (226 aa)
gphPhosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (235 aa)
Aave_0598PFAM: GtrA family protein; KEGG: mfa:Mfla_1376 GtrA-like protein. (134 aa)
Aave_0599PFAM: glycosyl transferase, family 2; KEGG: lpn:lpg2478 glycosyltransferase, group 2 family protein (glycan biosynthesis). (343 aa)
Aave_0600KEGG: reu:Reut_B3508 putative 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family. (507 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (307 aa)
Aave_0871PFAM: glycosyl transferase, family 2; KEGG: pol:Bpro_1115 glycosyl transferase, family 2. (694 aa)
pgiPFAM: phosphoglucose isomerase (PGI); KEGG: pol:Bpro_0753 glucose-6-phosphate isomerase; Belongs to the GPI family. (532 aa)
Aave_0948KEGG: dar:Daro_2389 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase, type II; Nucleotidyl transferase; Cupin 2, conserved barrel domain protein. (505 aa)
Aave_0949PFAM: UDP-glucose/GDP-mannose dehydrogenase; KEGG: msu:MS1501 WecC protein; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (432 aa)
Aave_0952PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: cvi:CV4124 probable aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (366 aa)
Aave_0953PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: tth:TTC0285 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (360 aa)
Aave_0957PFAM: glycosyl transferase, group 1; KEGG: ctc:CTC02266 glycosyl transferase. (397 aa)
Aave_0958PFAM: glycosyl transferase, group 1; KEGG: ade:Adeh_2772 glycosyl transferase, group 1. (401 aa)
Aave_0960PFAM: glycosyl transferase, group 1; KEGG: chu:CHU_2781 A-glycosyltransferase-related protein, glycosyltransferase family 4 protein. (430 aa)
Aave_0962KEGG: sth:STH1376 hypothetical protein. (378 aa)
Aave_0963PFAM: glycosyl transferase, group 1; KEGG: eba:ebA1527 mannosyltransferase. (369 aa)
Aave_0964PFAM: glycosyl transferase, family 2; glycosyl transferase, group 1; KEGG: eba:ebA1565 glycosyl transferase. (613 aa)
Aave_1037KEGG: rme:Rmet_4161 putative transmembrane protein. (457 aa)
Aave_1038PFAM: glycosyl transferase, group 1; KEGG: rso:RSc2271 hypothetical protein. (512 aa)
Aave_1039KEGG: rso:RSc2272 probable transmembrane protein. (337 aa)
Aave_1040KEGG: rme:Rmet_4158 putative transmembrane protein. (467 aa)
Aave_1041KEGG: rso:RSc2274 putative lipoprotein. (184 aa)
Aave_1042PFAM: Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; KEGG: rso:RSc2275 putative signal peptide protein. (1345 aa)
Aave_1043KEGG: rso:RSc2276 putative signal peptide protein. (941 aa)
Aave_1206KEGG: bur:Bcep18194_C7394 hypothetical protein. (306 aa)
Aave_1207PFAM: glycosyl transferase, group 1; KEGG: pfo:Pfl_2019 glycosyl transferase, group 1. (323 aa)
Aave_1209PFAM: sugar transferase; KEGG: rme:Rmet_2718 sugar transferase. (436 aa)
Aave_1210PFAM: glycosyl transferase, group 1; KEGG: rme:Rmet_2717 glycosyl transferase, group 1. (373 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
kdsATIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: pol:Bpro_3182 2-dehydro-3-deoxyphosphooctonate aldolase. (285 aa)
Aave_1382Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (796 aa)
lpxDUDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (333 aa)
fabZ3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (146 aa)
lpxAacyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (262 aa)
lpxBlipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (383 aa)
fbpPFAM: Inositol phosphatase/fructose-1,6-bisphosphatase; KEGG: pol:Bpro_1586 inositol phosphatase/fructose-1,6-bisphosphatase. (335 aa)
Aave_2004KEGG: mfa:Mfla_2213 hypothetical protein. (205 aa)
glgEAlpha amylase, catalytic region; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. (707 aa)
glgB1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (677 aa)
Aave_2065PFAM: glycosyl transferase, group 1; KEGG: aeh:Mlg_2350 glycosyl transferase, group 1. (407 aa)
Aave_2068KEGG: aeh:Mlg_2351 hypothetical protein. (394 aa)
Aave_2074Trehalose 6-phosphate synthase; PFAM: glycosyl transferase, family 20; KEGG: rso:RS01697 probable trehalose-6-phosphate synthase (alpha,alpha-trehalose-phosphate synthase UDP-forming) protein. (548 aa)
Aave_2172PFAM: acyltransferase 3; KEGG: pol:Bpro_3139 acyltransferase 3. (393 aa)
Aave_2193PFAM: sulfatase; protein of unknown function DUF1705; KEGG: pol:Bpro_3130 sulfatase. (542 aa)
Aave_2259Gluconolactonase; PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: mxa:MXAN_3250 senescence marker protein-30 family protein. (315 aa)
lpxHUDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (277 aa)
Aave_2532PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: bpm:BURPS1710b_2735 low molecular weight protein-tyrosine-phosphatase. (162 aa)
kdsB3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (263 aa)
lpxKlipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (347 aa)
Aave_2591Gluconolactonase; PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: pst:PSPTO_1052 senescence marker protein-30 family protein. (312 aa)
Aave_2623Phosphohistidine phosphatase, SixA; PFAM: Phosphoglycerate mutase; KEGG: rfr:Rfer_2018 phosphohistidine phosphatase, SixA. (153 aa)
Aave_2634KEGG: rfr:Rfer_2901 putative inner membrane transmembrane protein. (581 aa)
Aave_2820Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (450 aa)
Aave_2849KEGG: xcv:XCV4246 putative acetyltransferase. (187 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (435 aa)
Aave_2984Maltooligosyl trehalose hydrolase; KEGG: tbd:Tbd_1173 alpha amylase, catalytic subdomain; TIGRFAM: malto-oligosyltrehalose trehalohydrolase; PFAM: glycoside hydrolase, family 13 domain protein; alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain. (607 aa)
glgAGlycogen synthase (ADP-glucose); Synthesizes alpha-1,4-glucan chains using ADP-glucose. (508 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (247 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (474 aa)
Aave_4061PFAM: acyltransferase 3; KEGG: xom:XOO_0713 putative O-antigen acetylase. (351 aa)
Aave_4063Hypothetical protein. (468 aa)
Aave_4064Hypothetical protein; KEGG: mta:Moth_2476 transporter. (140 aa)
Aave_4065PFAM: glycosyl transferase, family 2; KEGG: pfl:PFL_5488 glycosyl transferase, group 2 family protein. (338 aa)
Aave_4140PFAM: glycosyl transferase, family 4; KEGG: pol:Bpro_3998 glycosyl transferase, family 4. (367 aa)
Aave_4141KEGG: net:Neut_0179 glycosyl transferase, family 2. (262 aa)
Aave_4142PFAM: glycosyl transferase, family 2; Methionine biosynthesis MetW; Methyltransferase type 11; Methyltransferase type 12; KEGG: rru:Rru_B0044 glycosyl transferase, family 2. (1287 aa)
Aave_4164Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (291 aa)
Aave_4210Trehalose 6-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. (245 aa)
Aave_4212Trehalose 6-phosphate synthase; Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family. (459 aa)
Aave_4328KEGG: pfl:PFL_4879 hypothetical protein. (128 aa)
Aave_4330PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: dvu:DVUA0045 aminotransferase, DegT/DnrJ/EryC1/StrS family; Belongs to the DegT/DnrJ/EryC1 family. (412 aa)
Aave_4366PFAM: acyltransferase 3; KEGG: mxa:MXAN_1041 acyltransferase family protein. (386 aa)
Aave_4407PFAM: glycosyl transferase, family 2; glycosyl transferase, group 1; KEGG: xcb:XC_2258 O-antigen biosynthesis protein. (1359 aa)
Aave_4576Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
Aave_4585TIGRFAM: transketolase; PFAM: Transketolase domain protein; Transketolase, central region; KEGG: pol:Bpro_4827 transketolase; Belongs to the transketolase family. (695 aa)
Aave_4610PFAM: sulfatase; KEGG: pfo:Pfl_2584 sulfatase. (592 aa)
Aave_4697PFAM: acyltransferase 3; KEGG: bur:Bcep18194_B2871 acyltransferase 3. (342 aa)
Aave_4784TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; KEGG: pol:Bpro_4897 phosphatase KdsC. (204 aa)
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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