STRINGSTRING
Aave_1207 Aave_1207 Aave_0268 Aave_0268 pyrE pyrE Aave_0476 Aave_0476 Aave_0529 Aave_0529 trpD trpD queA queA Aave_0600 Aave_0600 ftsW ftsW murG murG mtgA mtgA Aave_0844 Aave_0844 mrdB mrdB Aave_0871 Aave_0871 Aave_0909 Aave_0909 Aave_0957 Aave_0957 Aave_0958 Aave_0958 Aave_0960 Aave_0960 Aave_0962 Aave_0962 Aave_0963 Aave_0963 Aave_0964 Aave_0964 pncB pncB Aave_0995 Aave_0995 hisG hisG hisH hisH Aave_1038 Aave_1038 hisF hisF Aave_1206 Aave_1206 Aave_1210 Aave_1210 Aave_1341 Aave_1341 Aave_1435 Aave_1435 lgt lgt cobT cobT Aave_1617 Aave_1617 Aave_1633 Aave_1633 Aave_1649 Aave_1649 Aave_1772 Aave_1772 Aave_1787 Aave_1787 lpxB lpxB ppnP ppnP purF purF Aave_1957 Aave_1957 glgE glgE glgB glgB Aave_2065 Aave_2065 Aave_2068 Aave_2068 Aave_2074 Aave_2074 Aave_2104 Aave_2104 Aave_2357 Aave_2357 Aave_2469 Aave_2469 Aave_2475 Aave_2475 Aave_2650 Aave_2650 Aave_2727 Aave_2727 Aave_2820 Aave_2820 glgA glgA Aave_2991 Aave_2991 upp upp pncB-2 pncB-2 mltG mltG Aave_3471 Aave_3471 Aave_3669 Aave_3669 Aave_3851 Aave_3851 rlpA rlpA Aave_4140 Aave_4140 Aave_4142 Aave_4142 Aave_4212 Aave_4212 Aave_4407 Aave_4407 tgt tgt Aave_4659 Aave_4659 Aave_4678 Aave_4678 apt apt
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Aave_1207PFAM: glycosyl transferase, group 1; KEGG: pfo:Pfl_2019 glycosyl transferase, group 1. (323 aa)
Aave_0268PFAM: glycosyl transferase, group 1; KEGG: sth:STH1101 glycosyl transferase. (387 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (239 aa)
Aave_0476PFAM: Lytic transglycosylase, catalytic; KEGG: rme:Rmet_2520 lytic transglycosylase, catalytic. (256 aa)
Aave_0529PFAM: Lytic transglycosylase, catalytic; KEGG: xac:XAC2256 hypothetical protein. (202 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (345 aa)
queAQueuosine biosynthesis protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (369 aa)
Aave_0600KEGG: reu:Reut_B3508 putative 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family. (507 aa)
ftsWCell division-specific peptidoglycan biosynthesis regulator FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (427 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (355 aa)
mtgAMonofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (244 aa)
Aave_0844PFAM: O-antigen polymerase; KEGG: pol:Bpro_4672 O-antigen polymerase. (556 aa)
mrdBCell elongation-specific peptidoglycan biosynthesis regulator RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (386 aa)
Aave_0871PFAM: glycosyl transferase, family 2; KEGG: pol:Bpro_1115 glycosyl transferase, family 2. (694 aa)
Aave_0909PFAM: phosphoribosyltransferase; KEGG: rfr:Rfer_1379 phosphoribosyltransferase. (174 aa)
Aave_0957PFAM: glycosyl transferase, group 1; KEGG: ctc:CTC02266 glycosyl transferase. (397 aa)
Aave_0958PFAM: glycosyl transferase, group 1; KEGG: ade:Adeh_2772 glycosyl transferase, group 1. (401 aa)
Aave_0960PFAM: glycosyl transferase, group 1; KEGG: chu:CHU_2781 A-glycosyltransferase-related protein, glycosyltransferase family 4 protein. (430 aa)
Aave_0962KEGG: sth:STH1376 hypothetical protein. (378 aa)
Aave_0963PFAM: glycosyl transferase, group 1; KEGG: eba:ebA1527 mannosyltransferase. (369 aa)
Aave_0964PFAM: glycosyl transferase, family 2; glycosyl transferase, group 1; KEGG: eba:ebA1565 glycosyl transferase. (613 aa)
pncBNicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (398 aa)
Aave_0995KEGG: rfr:Rfer_2918 penicillin-binding protein 1A; TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase. (797 aa)
hisGATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (222 aa)
hisHImidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (222 aa)
Aave_1038PFAM: glycosyl transferase, group 1; KEGG: rso:RSc2271 hypothetical protein. (512 aa)
hisFImidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (266 aa)
Aave_1206KEGG: bur:Bcep18194_C7394 hypothetical protein. (306 aa)
Aave_1210PFAM: glycosyl transferase, group 1; KEGG: rme:Rmet_2717 glycosyl transferase, group 1. (373 aa)
Aave_1341PFAM: Lytic transglycosylase, catalytic; KEGG: pol:Bpro_3164 lytic transglycosylase, catalytic. (281 aa)
Aave_1435PFAM: phosphoribosyltransferase; KEGG: rfr:Rfer_2295 phosphoribosyltransferase. (174 aa)
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (270 aa)
cobTNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (357 aa)
Aave_1617TIGRFAM: phage portal protein, HK97 family; PFAM: phage portal protein; KEGG: ppu:PP_3879 phage portal protein, HK97 family. (426 aa)
Aave_1633KEGG: mag:amb0396 hypothetical protein. (138 aa)
Aave_1649KEGG: pol:Bpro_3073 hypothetical protein. (362 aa)
Aave_1772TIGRFAM: phage portal protein, HK97 family; PFAM: phage portal protein; KEGG: eba:ebA5484 putative phage portal protein. (451 aa)
Aave_1787KEGG: ppu:PP_1583 structural protein P5, putative. (138 aa)
lpxBlipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (383 aa)
ppnPProtein of unknown function DUF1255; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (105 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (501 aa)
Aave_1957TIGRFAM: penicillin-binding protein 1C; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase; Penicillin-binding domain protein; KEGG: rme:Rmet_3529 penicillin-binding protein 1C. (784 aa)
glgEAlpha amylase, catalytic region; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. (707 aa)
glgB1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (677 aa)
Aave_2065PFAM: glycosyl transferase, group 1; KEGG: aeh:Mlg_2350 glycosyl transferase, group 1. (407 aa)
Aave_2068KEGG: aeh:Mlg_2351 hypothetical protein. (394 aa)
Aave_2074Trehalose 6-phosphate synthase; PFAM: glycosyl transferase, family 20; KEGG: rso:RS01697 probable trehalose-6-phosphate synthase (alpha,alpha-trehalose-phosphate synthase UDP-forming) protein. (548 aa)
Aave_2104PFAM: glycosyl transferase, family 3; KEGG: pol:Bpro_3280 glycosyl transferase, family 3. (308 aa)
Aave_2357KEGG: mag:amb0396 hypothetical protein. (140 aa)
Aave_2469PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase; KEGG: rme:Rmet_4835 glycosyl transferase, family 51. (846 aa)
Aave_2475PFAM: protein of unknown function DUF152; KEGG: rfr:Rfer_2564 protein of unknown function DUF152; Belongs to the multicopper oxidase YfiH/RL5 family. (269 aa)
Aave_2650PFAM: Lytic transglycosylase, catalytic; MLTD_N domain protein; KEGG: pol:Bpro_2278 lytic transglycosylase, catalytic. (514 aa)
Aave_2727PFAM: Lytic transglycosylase, catalytic; KEGG: mta:Moth_1608 lytic transglycosylase, catalytic. (192 aa)
Aave_2820Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (450 aa)
glgAGlycogen synthase (ADP-glucose); Synthesizes alpha-1,4-glucan chains using ADP-glucose. (508 aa)
Aave_2991PFAM: Lytic transglycosylase, catalytic; KEGG: rfr:Rfer_2657 lytic transglycosylase, catalytic. (295 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (215 aa)
pncB-2Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (402 aa)
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (334 aa)
Aave_3471KEGG: psp:PSPPH_4981 hypothetical protein. (218 aa)
Aave_3669PFAM: Lytic transglycosylase, catalytic; KEGG: pol:Bpro_0832 lytic transglycosylase, catalytic. (226 aa)
Aave_3851KEGG: pol:Bpro_0902 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. (297 aa)
rlpARare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (108 aa)
Aave_4140PFAM: glycosyl transferase, family 4; KEGG: pol:Bpro_3998 glycosyl transferase, family 4. (367 aa)
Aave_4142PFAM: glycosyl transferase, family 2; Methionine biosynthesis MetW; Methyltransferase type 11; Methyltransferase type 12; KEGG: rru:Rru_B0044 glycosyl transferase, family 2. (1287 aa)
Aave_4212Trehalose 6-phosphate synthase; Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family. (459 aa)
Aave_4407PFAM: glycosyl transferase, family 2; glycosyl transferase, group 1; KEGG: xcb:XC_2258 O-antigen biosynthesis protein. (1359 aa)
tgttRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] (390 aa)
Aave_4659PFAM: UDP-glucuronosyl/UDP-glucosyltransferase; KEGG: bja:bll2692 putative glycosyltransferase. (443 aa)
Aave_4678KEGG: rfr:Rfer_1264 O-antigen polymerase. (556 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (184 aa)
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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