STRINGSTRING
mrdA mrdA Aave_0332 Aave_0332 ftsI ftsI murE murE murF murF mraY mraY murD murD murG murG murC murC ddl ddl mtgA mtgA Aave_0995 Aave_0995 murA murA Aave_1827 Aave_1827 murB murB Aave_1957 Aave_1957 uppP uppP Aave_2469 Aave_2469 Aave_4568 Aave_4568 Aave_4580 Aave_4580
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mrdACell elongation-specific peptidoglycan D,D-transpeptidase; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (648 aa)
Aave_0332Penicillin-binding protein 6; PFAM: beta-lactamase; peptidase S11, D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: pol:Bpro_0250 serine-type D-Ala-D-Ala carboxypeptidase; Serine peptidase; MEROPS family S11; Belongs to the peptidase S11 family. (393 aa)
ftsIPeptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (581 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (519 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (501 aa)
mraYPhospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (392 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (667 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (355 aa)
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (475 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation. (334 aa)
mtgAMonofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (244 aa)
Aave_0995KEGG: rfr:Rfer_2918 penicillin-binding protein 1A; TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase. (797 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (434 aa)
Aave_1827Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (247 aa)
murBUDP-N-acetylmuramate dehydrogenase; Cell wall formation. (357 aa)
Aave_1957TIGRFAM: penicillin-binding protein 1C; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase; Penicillin-binding domain protein; KEGG: rme:Rmet_3529 penicillin-binding protein 1C. (784 aa)
uppPUndecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (274 aa)
Aave_2469PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase; KEGG: rme:Rmet_4835 glycosyl transferase, family 51. (846 aa)
Aave_4568D-Ala-D-Ala carboxypeptidase PBP3; TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13, D-Ala-D-Ala carboxypeptidase C; KEGG: rfr:Rfer_0191 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; Serine peptidase; MEROPS family S13. (486 aa)
Aave_4580PFAM: phosphoesterase, PA-phosphatase related; KEGG: bpm:BURPS1710b_A1526 PAP2 family protein. (197 aa)
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.